Human Dietary Exposure to Hexachlorobenzene in Catalonia, Spain

2008 ◽  
Vol 71 (10) ◽  
pp. 2148-2152 ◽  
Author(s):  
ROSER MARTÍ-CID ◽  
JUAN M. LLOBET ◽  
VICTORIA CASTELL ◽  
JOSE L. DOMINGO

The concentrations of hexachlorobenzene (HCB) were measured in samples of foodstuffs widely consumed by the population of Catalonia, Spain. Food samples were randomly acquired in 12 cities of Catalonia between March and June of 2006. HCB levels were determined by high-resolution gas chromatography–high-resolution mass spectrometry. The dietary intake of HCB was subsequently estimated for the population of Catalonia, and the results were compared with those of a survey performed in 2000. The highest HCB concentrations were found in oils and fats, fish and seafood, and dairy products, with mean levels of 0.481, 0.330, and 0.284 ng/g of fresh weight, respectively. HCB intake was estimated for four population groups: children, adolescents, adults, and seniors (aged > 65 years). The highest and lowest HCB intake corresponded to children and seniors, respectively. Similar results were found in our 2000 survey. For a standard male adult of 70-kg body weight, in the 2000 study, total dietary intake of HCB was 166.2 ng/day (2.4 ng/kg of body weight per day), whereas in the current survey the intake was 71.6 ng/day (1.0 ng/kg of body weight per day). On a body-weight basis, it means a decrease of 57%, which was mainly due to the important reductions in the contribution of dairy products (mainly cheese), as well as those of meat and meat products and fish and seafood. All the intakes are considerably lower than the World Health Organization tolerable daily intake, which is 0.17 μg/kg/day for noncancer effects and 0.16 μg/kg/day for neoplastic effects in humans.

2021 ◽  
Vol 854 (1) ◽  
pp. 012057
Author(s):  
D Milicevic ◽  
D Vranic ◽  
V Koricanac ◽  
Z Petrovic ◽  
A Bajcic ◽  
...  

Abstract The aim of this study was to assess the dietary exposure of phosphorus in the Serbian adult population by combining individual consumption data with available data for analysed meat products. During a three years period of investigation (2018 to 2020), a total of 682 samples consisting of 425 cooked sausages and 257 smoked meat products were collected from different local retail markets across the Serbia to examine phosphorus concentrations. The mean phosphorus concentration, expressed as P2O5, varied from 4.68±0.88 g/kg to 6.05±1.30 g/kg in finely minced cooked sausages and smoked meat products, respectively. The average estimated daily dietary intake (exposure) (EDI) of phosphorus ranged from 1.115 mg/kg BW (body weight)/day (finely minced cooked sausages) to 1.441 mg/kg BW/day (smoked meat products). Phosphorus dietary intake (exposure) averaged 3.08% of the acceptable daily intake (ADI: 40 mg/kg BW/day). According to our results, the average phosphorus exposure in the Serbian adult population from consumption of these meat products is far below the European ADI.


2003 ◽  
Vol 66 (12) ◽  
pp. 2325-2331 ◽  
Author(s):  
GEMMA FALCÓ ◽  
JOSE L. DOMINGO ◽  
JUAN M. LLOBET ◽  
ANGEL TEIXIDÓ ◽  
CONRAD CASAS ◽  
...  

The dietary intake of 16 polycyclic aromatic hydrocarbons (PAHs) (naphthalene, acenaphthylene, acenaphthene, fluorene, phenanthrene, anthracene, fluoranthene, pyrene, benz[a]anthracene, chrysene, benzo[b]fluoranthene, benzo[k]fluoranthene, benzo[a]pyrene, dibenz[a,h]anthracene, benzo[g,h,i]perylene, and indeno[1,2,3-c,d]pyrene) by the general population of Catalonia, Spain, was calculated. Concentrations of PAHs in food samples randomly acquired in seven cities of Catalonia from June to August 2000 were measured. Eleven food groups were included in the study. High-performance liquid chromatography was used to analyze PAHs. The dietary intakes of total and carcinogenic PAHs was calculated for five population groups: children, adolescents, male adults, female adults, and seniors. Among the analyzed PAHs, there was a predominance of phenanthrene (16.7 μg/kg) and pyrene (10.7 μg/kg). By food group, the highest levels of total PAHs were detected in cereals (14.5 μg/kg) and in meat and meat products (13.4 μg/kg). The mean estimated dietary intake of the sum of the 16 PAHs was as follows: male adults, 8.4 μg/day; adolescents, 8.2 μg/day; children, 7.4 μg/day; seniors, 6.3 μg/day; female adults, 6.3 μg/day. The calculated daily intake of PAHs would be associated with a 5/106 increase in the risk for the development of cancer in a male adult with a body weight of 70 kg.


2003 ◽  
Vol 66 (3) ◽  
pp. 479-484 ◽  
Author(s):  
JUAN M. LLOBET ◽  
ANA BOCIO ◽  
JOSE L. DOMINGO ◽  
ANGEL TEIXIDÓ ◽  
CONRAD CASAS ◽  
...  

From June to August 2000, food samples were randomly acquired in seven cities in Catalonia, Spain. Polychlorinated biphenyl (PCB) concentrations were determined for 108 samples of vegetables, fruits, pulses, cereals, fish and shellfish, meats and meat products, eggs, milk and dairy products, and oils and fats. Levels of 11 PCB congeners (IUPAC 28, 52, 77, 101, 105, 118, 126, 138, 153, 169, and 180) were determined by high-resolution gas chromatography–high-resolution mass spectrometry. For toxic equivalent (TEQ) calculations, World Health Organization (WHO) toxicity equivalent factors (WHO-TEFs) were used. The highest levels of most congeners were found in fish and shellfish (11,864.18 ng/kg [wet weight]), and the next highest levels, which were substantially lower, were found in milk and dairy products (674.50 ng/kg [wet weight]). For the general population of Catalonia, the total dietary intake of PCBs was found to be 150.13 pg WHO-TEQ/day. The largest contribution to this intake came from fish and shellfish (82.87 pg WHO-TEQ/day) and dairy products (29.38 pg WHO-TEQ per day). A relatively large contribution was also noted for cereals (11.36 pg WHO-TEQ/day). Among the PCB congeners determined in this study, PCB 126 showed the largest contribution to total TEQ intake (50.56%). The data obtained in this study should be useful in risk assessment with regard to human PCB exposure through food in Catalonia.


Author(s):  
Claudia Foerster ◽  
Liliana Zúñiga-Venegas ◽  
Pedro Enríquez ◽  
Jacqueline Rojas ◽  
Claudia Zamora ◽  
...  

Persistent organic pollutants (POPs) are organic compounds that resist biochemical degradation, moving long distances across the atmosphere before deposition occurs. Our goal was to provide up-to-date data on the levels of polychlorinated dibenzo-p-dioxins/furans (PCDD/Fs) and dioxin-like polychlorinated biphenyls (DL-PCBs) in breast milk from Chilean women and to estimate the exposure of infants due to breast milk consumption. In Chile, we conducted a cross-sectional study based on methodologies proposed by the WHO, with a sample of 30 women recruited from three defined areas: 10 from the Arica Region (urban; Arica and Parinacota Region), 10 from Coltauco (rural; O’Higgins Region), and 10 from Molina (40% rural; Maule Region). High-resolution gas chromatography coupled with high-resolution mass spectrometry (HRGC/HRMS) was performed on pooled samples from each area. We calculated equivalent toxic concentrations (WHO-TEQ) based on the current WHO Toxic Equivalency Factors (TEF). The minimum and maximum values of ∑ PCDDs/Fs + DL-PCBs-TEQ were 4.317 pg TEQ/g fat in Coltauco and 6.31 pg TEQ/g fat in Arica. Molina had a total TEQ of 5.50 pg TEQ/g fat. The contribution of PCDD/Fs was approximately five-fold higher than that of DL-PCBs. The Estimated Daily Intake (EDI) of ∑ PCDDs/Fs + DL-PCBs based on the three pooled samples ranged between 6.71 and 26.28 pg TEQ/kg body weight (bw)/day, with a mean intake of 16.11 (±6.71) pg TEQ/kg bw/day in breastfed children from 0 to 24 months old. These levels were lower than those reported in international studies. Despite the fact that the observed levels were low compared to those in most industrialized countries, the detection of a variety of POPs in breast milk from Chilean women indicates the need for follow-up studies to determine whether such exposures during childhood could represent a health risk in adulthood.


2012 ◽  
Vol 30 (No. 3) ◽  
pp. 268-275 ◽  
Author(s):  
K. Joudalová ◽  
Z. Réblová

The intake of extractable antioxidants in theCzech Republicwas studied using the FRAP (ferric reducing antioxidant potential) method applied to water-methanol extracts. The daily intake of these antioxidants was 16.6 mmol generated Fe(II) for men and 15.0 mmol for women (i.e. 8300 and 7500 μmol Trolox equivalents). The largest sources of antioxidants were coffee (43.1% of overall intake for men and 54.6% for women) and beer (15% for men vs. 1.8% for women). Other significant sources of antioxidants were tea, vegetables and vegetable products (including potatoes and potato products), fruit and fruit products, cereal products, wine, sugars and sweets, spices and meat and meat products. Small amounts of antioxidants (less than 1.0% of overall intake) were supplied by nuts and seeds, milk and milk products and fats, while pulses, eggs and egg products, convenience foods and cheese were insignificant sources of antioxidants. Within the fruit and fruit products category, apples were the most significant source of extractable antioxidants, and in the vegetable and vegetable products category, peppers were the largest source of antioxidants.  


Author(s):  
Mingna Sun ◽  
Zhou Tong ◽  
Xu Dong ◽  
Yue Chu ◽  
Mei Wang ◽  
...  

Chlorfluazuron is used as a highly effective insect growth regulator to control a variety of crop pests. However, residues of this pesticide have been shown to be harmful to human health. To evaluate the residual dissipation pattern and risk for dietary intake of chlorfluazuron in various vegetables, a solid phase extraction-ultra performance liquid chromatography-tandem mass spectrometry method was established to analyze chlorfluazuron residues in Chinese cabbage, Chinese kale, Chinese lettuce, and cauliflower. The sample was extracted with acetonitrile and purified using an SPE amino column. The average recovery of the target sample in the analyzed four vegetables was between 75.0% and 104.1%, and the relative standard deviation was between 2.5% and 9.6%. The precision and accuracy of the analysis met the requirements of residue analysis standards. Dissipation kinetic testing of chlorfluazuron in different vegetables showed a half-life of 2.4–12.6 days, with a rapid dissipation rate. The estimated daily intake of the chlorfluazuron was 0.753–1.661 μg/(kg bw·d), and the risk quotient was 0.15–0.35. It showed that chlorfluazuron had a low risk of chronic dietary intake from vegetables in different populations in China. The results of this study has described the degradation rate of chlorfluazuron in four vegetables, evaluated the risk of dietary exposure to Chinese residents. Therefore, it provides supporting data and empirical basis for guiding the reasonable use of chlorfluazuron in vegetable production and in evaluating its dietary intake risk in vegetables.


2011 ◽  
Vol 74 (8) ◽  
pp. 1374-1378 ◽  
Author(s):  
Y. Z. FENG ◽  
X. H. LU ◽  
B. TAO ◽  
M. H. PANG ◽  
Y. C. LIU ◽  
...  

A total of 255 corn samples collected in 2010 from three main corn production provinces of China (Liaoning, Shandong, and Henan) were analyzed for contamination with fumonisins (FB1 and FB2). The incidence of contamination was significantly higher in samples from Liaoning than in samples from the other two provinces. Approximately 80.0% of the samples from Liaoning were contaminated with fumonisins, with a mean total fumonisin concentration of 3,990 ng/g. In contrast, the mean total fumonisin concentrations were 845 and 665 ng/g in samples from Shandong and Henan, respectively. The probable daily intake of fumonisins (0.3 μg/kg of body weight) is within the provisional maximum tolerable daily intake of 2.0 μg/kg of body weight set by the Joint Food and Agriculture Organization and World Health Organization Expert Committee on Food Additives.


Author(s):  
S. Uday Kumar Reddy ◽  
Sirshendu Chaudhuri ◽  
Syeda Fathima Amrin ◽  
Gunasekaran Rabeka

Background: Nutritional status and dietary intake during adolescent period play a crucial role in their mental and physical development. Objectives of the present study were to estimate the prevalence of undernutrition, as defined by the World Health Organization (WHO), among unmarried adolescent girls in rural area of Chittoor district; to estimate the average daily intake of different macro and micro-nutrients, i.e., calorie, protein and iron, by the same group by 24-hour dietary recall method; and to identify individual and family level determinants for undernutrition and decreased intake of nutrients.Methods: In this cross-sectional community-based survey anthropometric measurements were done, and dietary intake of unmarried adolescent girls was assessed by 24-hour recall method.Results: Majority is suffering from poor nutrient intake. This is more prominent for calcium [25.1-40.9% of the recommended daily allowance (RDA)] and energy intake (68.6-88.9% of RDA). Only 55% of the adolescents get iron supplementation; rests consume minimal iron (8.5gm) on average. Prevalence of thinness and stunting was 29.4% (95% CI: 20.4%, 38.4%) and 21.4% (95% CI: 13.3, 29.5%) respectively. Economic and housing conditions were associated with low dietary intake and poor nutritional status. Considerable cluster-wise variation exists for both the conditions.Conclusions: High prevalence of stunting and thinness together with substantial macro and micro-nutrient deficiency exist among adolescent girls. Existing national programs for this age group needs adequate supervision. Awareness development regarding locally available low-cost nutritious food together with periodic anthropometric measurements is required. 


Nutrients ◽  
2022 ◽  
Vol 14 (2) ◽  
pp. 242
Author(s):  
Jelena Milešević ◽  
Danijela Vranić ◽  
Mirjana Gurinović ◽  
Vladimir Korićanac ◽  
Branka Borović ◽  
...  

This study provides the data on dietary exposure of Serbian children to nitrites and phosphorus from meat products by combining individual consumption data with available analytical data of meat products. A total of 2603 and 1900 commercially available meat products were categorized into seven groups and analysed for nitrite and phosphorous content. The highest mean levels of nitrite content, expressed as NaNO2, were found in finely minced cooked sausages (40.25 ± 20.37 mg/kg), followed by canned meat (34.95 ± 22.12 mg/kg) and coarsely minced cooked sausages (32.85 ± 23.25 mg/kg). The EDI (estimated daily intake) of nitrites from meat products, calculated from a National Food Consumption Survey in 576 children aged 1–9 years, indicated that the Serbian children population exceeded the nitrite ADI (acceptable daily intake) proposed by EFSA (European Food Safety Authority) in 6.4% of children, with a higher proportion in 1–3-year-old participants. The mean phosphorus concentration varied from 2.71 ± 1.05 g/kg to 6.12 ± 1.33 g/kg in liver sausage and pate and smoked meat products, respectively. The EDI of phosphorus from meat products was far below the ADI proposed by EFSA, indicating that the use of phosphorus additives in Serbian meat products is generally in line with legislation.


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