scholarly journals Efficacy of Mefenamic acid and Ginger on Pain Relief in Primary Dysmenorrhea Among Basic Sciences Students of Nepalgunj Medical College

2020 ◽  
Vol 2 (1) ◽  
pp. 4-10
Author(s):  
Ankita Singh ◽  
Bijay Aryal ◽  
Sushma Deo

Introduction: Primary dysmenorrhea has been reported as the most common cause of regular absenteeism among young women. Pain affects daily activities and quality of life. The aim of the study was to compare the efficacy between mefenamic acid (Meftal) and ginger capsules (Remezy) among Basic Sciences Students of Nepalgunj Medical College (NGMC), Chisapani. Adverse effects, if any, were also observed in both Meftal and ginger groups. Methodology: This was a prospective cross-sectional study conducted from July 2018 to February 2019. Out of 104 students, 87 were suffering menstrual pain. These 87 individuals received Mefenamic acid (Meftal) 500mg twice a day for three days and the same 87 individuals, in their next month of period, took ginger capsules (Remezy) 500mg twice daily for three days. Medication was started on the first day of their menstruation. The severity of pain before and after the medication was recorded with the help of a multi-dimensional scoring system (MSS). All the data were directly entered into SPSS 20.0 and compiled, analyzed and expressed in tables and charts. Results: Out of 104, 87 (83.7%) students had experienced menstrual pain. The mean±S.D age of the students was 19.64±1.02 while the mean±S.D menarche age was 13.21±1.01. The pain severity of dysmenorrhea was significantly reduced (p<0.05) with both meftal and ginger intake in both the first and second months consecutively. However, a comparison of efficacy between the two medications showed no statistically significant difference (p>0.05). Adverse effects were found to be significantly higher in students receiving meftal tablets.     Conclusion: A high proportion of students had dysmenorrhea. Similar efficacy of ginger and meftal was observed with minimal adverse effects in ginger. Findings suggest the need for educating students on appropriate and effective management of dysmenorrhea.

Author(s):  
Dr. Hitesh Kumar Solanki ◽  
Dr. Omnath P Yadav ◽  
Dr. Anita J Gojiya

The study was conducted in department of physiology, B J Medical College, Ahmedabad from Mar. 2012 to Feb. 2013. This was a cross-sectional study to evaluate the effect of smoking on lung   function and serum lipids in asymptomatic smokers   and comparable non   smokers. The mean of the various spirometric parameters were calculated of the subjects for both the groups. The mean FVC in group I and group II was 2.60 ± 0.62 L and 4.10 ± 0.64L respectively. The mean FEV1 in group I was 1.91 ± 0.57L and     3.19 ± 0.77L in group II Group I had mean FEF25% - 75% and PEFR of 1.98 ± 0.67L/sec and 4.50 ± 1.57L/sec respectively. Group II had mean FEF25 – 75% of 4.22 ± 1.23L/sec and a mean PEFR of 7.22 ± 1.42L/sec. In young smokers and asymptomatic, still the spirometric values were significantly deranged as compared to controls. Even smokers with history of less pack years of smoking also had significant abnormalities of lung function. All he spirometric values in the two groups had statistically highly significant difference and were higher in non-smokers as compared to smokers. The spirometric values were reduced in smokers with history of smoking for as low as two pack years. Keywords: Progression, PFT, Asymptomatic & Smokers


2020 ◽  
Vol 11 (2) ◽  
pp. 124-129
Author(s):  
Lutfun Nahar ◽  
Ahmad Seraji ◽  
Md Shofiur Rahman ◽  
Md Redwan Ahsanullah

Study on the Thicknesses and the Girths of Tendoachilles of Human Cadavers. Background: Tendoachilles is the chief planter flexor of the ankle joint. It provides elastic energy storage in walking and running. The present study was planned to collect data to find out possible variations of thickness and girth between right and left leg of both male and female. Materials and methods: A cross sectional analytical type of study was conducted in the department of Anatomy, Dhaka Medical College, Dhaka, from July 2013 to June 2014. The data was collected from both right and left tendoachilles of 60 human cadaver taken from Anatomy Department of different Government and Nongovernment Medical Colleges in Dhaka city. After dissection thickness and girth of tendoachilles was measured and recorded. Results: Among 60 human cadaver, 30 are male and 30 are female. The mean thickness of tendoachilles was greater in right leg than in left leg at its junction with gastrocnemius in male, (P<0.001) at the level of 4 cm above its junction with calcaneus and at the level of its junction with calcaneus in both male and female. No significant difference was observed in the measurement of thickness of right and left tendoachilles at the level of its junction with gastrocnemius in female. Mean girth of tendoachilles was greater in right leg than in left leg at its junction with gastrocnemius, at the level of 4 cm above its junction with calcaneus and at the level of its junction with calcaneus in both male and female. Conclusions: The present study revealed that thickness and girth of tendoachilles was greater in right leg than in left leg which were statistically significant. The difference in thickness and girth can be useful during repair of rupture tendon by orthopaedic and plastic surgeon. J Shaheed Suhrawardy Med Coll, December 2019, Vol.11(2); 124-129


2019 ◽  
Vol 15 (2) ◽  
pp. 139-143
Author(s):  
Nripendra Tiwari ◽  
Deepesh Budhathoki ◽  
Iju Shrestha ◽  
Ram Timsina ◽  
Santosh Kumar Shah ◽  
...  

Background: Venous network of hand is superficially placed and is easy to trace for clinical purposes. Ce-phalic vein on lateral aspect and basilic vein on medial aspect of the hand are clinically important for inva-sive and surgical procedures. Thus the study of cephalic and basilic veins at dorsal venous arch of hand was dissected to observe for length of dorsal venous arch and the diameter and thickness of cephalic and basilic veins. Methods: This is a cross-sectional observational study conducted in 50 hands of cadavers (36 hands of male cadavers, 14 hands of female cadavers) in Department of Anatomy, Kathmandu Medical College Teaching Hospital, Duwakot. Cadavers were performed to measure the length of dorsal venous arch, diame-ter and thickness of cephalic and basilic vein on dorsum of hands. Results: The mean±s.d. length of dorsal venous arch in male cadaver (19.03±2.84 cm.) was significantly greater than in female (16.51±1.36 cm.).There was no significant difference in length of dorsal venous arch on right (18.22 ±2.47 cm.) and left side (18.42±3.05 cm.) in either sex. The mean±s.d thickness of basilic vein (0.10±0.01mm) in either sex was significantly greater than that of cephalic vein (0.09±0.01mm). Conclusions: The length of the dorsal ve-nous arch in male cadavers was found significantly greater than in female cadavers. The diameters based on external and internal circumference of basilic veins was found to be more than diameter of cephalic veins in both male and female cadavers. The thickness of basilic vein was found to be more (0.10±0.01mm) than that of cephalic vein (0.09±0.01mm) in cadaver of both sexes.


2021 ◽  
Vol 20 (3) ◽  
Author(s):  
Hanish Singh Jayasingh Chellammal ◽  
Mohamed Mansor Manan ◽  
Thayashini Kupusamy ◽  
Long Chiau Ming ◽  
Shafeeq Mohd Faizal

INTRODUCTION: Awareness on antibiotics resistance among outpatients in hospital settings is reasonably explored and this study aimed to investigate the sociodemographic impact and the level of acquaintance towards antibiotics practice and resistance. MATERIALS AND METHODS: This cross-sectional study was conducted on 270 patients from the outpatient department of KPJ Seremban Specialist Hospital (KPJSSH), Malaysia. A pre-validated questionnaire was used to collect the data on the demographics of the patients, their knowledge, attitude, and usage of antibiotics. The study was approved by the KPJUC ethics committee (KPJUC/RMC/BPH/EC/2017/104). RESULTS: The mean age of the respondents was 36 ± 11.07 years and 50.37% of them have moderate knowledge on antibiotics. The knowledge and attitude on antibiotics usage exhibited a significant difference (p=0.001) amongst these patients in association with literacy. The results showed that the literate respondents have significant knowledge on the identification of antibiotics (p=0.021), their roles, and adverse effects (p=0.004). The attitude of the respondents towards following the prescription was significantly associated with their literacy (p=0.004). CONCLUSION: This study reveals that respondents have the least knowledge on antibiotic course compliance and termination of therapy, which could lead to antimicrobial resistance. In conclusion, inculcating the knowledge of antimicrobial resistance, adverse effects, and course compliance among the patients may help overcome the national and global issues on multi-drug-resistant diseases.


2018 ◽  
Vol 17 (3) ◽  
pp. 388-394
Author(s):  
Lutfun Nahar ◽  
Ahmad Seraji ◽  
Soniya Fahmi ◽  
Khandaker Nadia Afreen ◽  
Mahbuba Aktar ◽  
...  

Background: Tendoachilles is the chief plantar flexor of the ankle joint. The present study was conducted to find out the possible variations of tendoachilles between the right and the left leg of both male and female.Materials and methods: A cross sectional observational study was conducted in the department of Anatomy, Dhaka Medical College, Dhaka, from July 2013 to June 2014. The data were collected from both the right and the left tendoachilles of 60 human cadavers taken from Anatomy Departments of different Government and Nongovernment Medical Colleges in Dhaka city. Among the 60 cadavers, 30 were male and 30 were female. After dissection, the length of tendoachilles and the breadths at different levels of tendoachilles were measured and recorded.Results: The mean length of tendoachilles was significantly greater in the right than in the left leg of both male and female. The tendoachilles was longer in male than in female in both the right and the left leg (P<0.01). There was significant positive correlation between the height of cadaver and the length of tendoachilles of both the right leg and the left leg in case of male. Positive correlation was also observed between the height of cadaver and the length of tendoachilles of both the legs in case of female, but that was not statistically significant. The mean breadths of tendoachilles were significantly greater in the right leg than in the left leg at its junction with gastrocnemius and at the level of its junction with calcaneus in both male and female and also in male than in female in both legs. Significant difference was observed between the breadth of right and left tendoachilles at the level of 4 cm above its junction with calcaneus in male but not in female (P>0.05).Conclusion: Significantly greater values were observed in the length and in most of the breadths of tendoachilles in the right leg of both sexes and in male in both legs. There was significant positive correlation between the height of cadaver and the length of tendoachilles of both legs in case of male, but, not in female.Bangladesh Journal of Medical Science Vol.17(3) 2018 p.388-394


Author(s):  
Yodi Ertandri ◽  
Syahredi S. Adnani ◽  
Hafni Bachtiar

Objective: To investigate whether chronic primary dysmenorrhoea will significantly increase cortisol levels in the body. This study can provide an overview of the importance of handling primary dysmenorrhoea so that it does not continue to become menstrual disorders.Method: This study used a cross-sectional comparative study method with a total sample of 26 subjects with 13 subjects included in the dysmenorrhea group and 13 other subjects belonging to the non-dysmenorrhea group. The study was conducted at Department of Obstetrics and Gynecology Faculty of Medicine Universitas Andalas network primary healthcare and Dr. M. Djamil Padang Central General Hospital. Data were analyzed using computational calculation of SPSS program with bivariate test using X2 test or chi-square test with a significance degree of 0.05.Results: Twenty six subjects (13 each group) have been sampled in this study, the mean age of the dysmenorrhea group was 26.23 ± 3.92 while the mean age of the non-dysmenorrhea group was 28.62 ± 7.10. The age difference between groups was not statistically significant with a value of p = 0.30 (p> 0.05). In the comparison of cortisol levels between the two groups, it was found that the dysmenorrhea group had a higher cortisol level of 72.3077 (7.2 µg / dL) compared to the non-dysmenorrhoea group of 60.3846 (6 µg / dL). Based on the results of the bivariate analysis using the chi-square test, the value of p = 0.148 (P> 0.05) showed that there was no significant difference between the cortisol levels of the group with chronic primary dysmenorrhea compared with the non-dysmenorrhea group.Conclusion: Chronic primary dysmenorrhea can not significantly increase cortisol levels in the body.Keywords: comparative study, chronic primary dysmenorrhea, cortisol levels, non-dysmenorrhea, menstrual disorders Abstrak Tujuan :Mengetahui apakah dismenorea primer kronis akan meningkatkan kadar kortisol dalam tubuh secara signifikan. Penelitian ini dapat memberikan gambaran pentingnya penanganan dismenorea primer agar tidak berlanjut menjadi gangguan menstruasi.Metode :Penelitian ini merupakan penelitian dengan desain potong lintang studi banding dengan jumlah total sampel sebanyak 26 subjek dengan rincian 13 subjek termasuk ke dalam kelompok dismenore dan 13 subjek lainnya termasuk ke dalam kelompok non-dismenore. Penelitian dilakukan di Puskesmas jejaring PPDS Obgyn FK Unand dan RSUP Dr. M. Djamil Padang. Data dianalisis menggunakan perhitungan komputasi program SPSS dengan uji bivariat menggunakan ujiX2 atau uji chi-square dengan derajat kemaknaan 0,05. Hasil : Dari 26 subjek (masing-masing 13 subjek) yang dijadikan sampel dalam penelitian ini, didapatkan usia rerata kelompok dismenore ialah 26,23 ± 3,92 sedangkan usia rerata kelompok non-dismenore ialah 28,62 ± 7,10. Perbedaan rerata usia antar kelompok ini tidak signifikan secara statistik dengan nilai p = 0,30 (p > 0,05). Pada perbandingan kadar kortisol antar kedua kelompok, didapatkan kelompok dismenore memiliki kadar kortisol yang lebih tinggi yaitu 72,3077 (7.2 µg/dL) dibandingkan dengan kelompok non-dismenorea yaitu 60,3846 (6 µg/dL). Berdasarkan hasil analisis bivariat menggunakan uji chi-square, didapatkan nilai p = 0,148 (P > 0,05) yang menunjukkan tidak adanya perbedaan yang signifikan antara kadar kortisol kelompok dengan dismenore primer kronis dibandingkan dengan kelompok non-dismenore.Kesimpulan : Dismenore primer kronis dapat meningkatkan kadar kortisol dalam tubuh secara signifikan.Kata kunci :   dismenore primer, gangguan menstruasi, kadar kortisol, kronis, tidak dismenore, studi perbandingan


Author(s):  
Yogesh M. Shah ◽  
Adit M. Garg ◽  
Gaurav Paliwal ◽  
Amir S. Ansari ◽  
Chandni Jain ◽  
...  

<p class="abstract"><strong>Background:</strong> Keloid is a common presentation in clinical practice. Symptoms due to keloid are mild, but disfigurement and functional impairment can be severe. It is difficult to treat. Intralesional, injection triamcinolone acetonide, has limited efficacy, causes adverse effects such as local dermal atrophy, telengiectasia and hypopigmentation. Injection verapamil is reported to have similar efficacy, but lesser side effects, and is cheaper. Aim was to study efficacy and adverse effects of intralesional verapamil in treatment of keloid.</p><p class="abstract"><strong>Methods:</strong> An open label study on 25 patients of keloid, either gender, age 11 to 55 years at a medical college hospital. Injection verapamil 2.5 mg/ml was administered intralesionally, at an interval of 3 weeks, for a total of 6 sittings, over a period of 18 weeks. Vancouver scar scale (VSS) was used to assess the improvement. The statistical analysis was done using SPSS version 21.0.<strong></strong></p><p class="abstract"><strong>Results:</strong> Median duration of keloids was 8 months. The mean VSS score before treatment was 7.68 which reduced to 4.28 after treatment. Mean percentage change in VSS score was 46.21%, very highly significant (p&lt;0.001). Physician’s assessment was ‘very good’ in 32.0% and 'excellent' in 8.0%. The complaint of post-procedure pain was present in almost all.</p><p class="abstract"><strong>Conclusions:</strong> Intralesional injection verapamil, gives very good to excellent improvement in 40% of patients of keloid. Post injection pain persists for more than 24 hours. Drug does not cause local dermal atrophy or hypopigmentation.</p>


2015 ◽  
Vol 3 (2) ◽  
pp. 78-82
Author(s):  
Nazma Farhat ◽  
Humaira Naushaba ◽  
Md Shahjahan Chowdhury ◽  
Mallika Karmakar

Background: Estimation of intercanthal width and biocular breadth from digital photography is important in the evaluation of several systemic syndromes, craniofacial abnormalities and in surgical treatments of post-traumatic telecanthus. Dysmorphologists employ canthal measurements in evaluating the degree of hypertelorism. So intercanthal width and biocular breadth values are very important for clinicians, ophthalmologists, plastic and reconstructive surgeons. The reliability of estimation of intercanthal width from biocular breadth by using multiplication factor is high.Objective: To make an attempt to determine the multiplication factor for estimation of intercanthal width.Materials and method: This is a cross sectional study conducted in the Anatomy department of Sir Salimullah Medical College, Dhaka, Bangladesh from January 2010 to June 2011. One hundred Bangladeshi 25 to 45 years old women were selected purposively for the study.Results: The mean±SD intercanthal width was 3.456±0.3585 cm. Multiplication factor for measuring intercanthal width from biocular breadth (9.348±0.7174 cm) was 0.369±0.0232 cm. The mean±SD of estimated intercanthal width was 3.449±0.2647 cm. No significant difference was found between the measured and estimated intercanthal width.Conclusion: Multiplication factor can be used to determine intercanthal width in Bangladeshi women though agreement test would have been done to generalize the finding.Delta Med Col J. Jul 2015; 3(2): 78-82


1970 ◽  
Vol 4 (2) ◽  
pp. 74-77
Author(s):  
Rukshana Ahmed ◽  
Shamim Ara

Pathological changes in the prostate gland occur commonly with advancing age including inflammation, atrophy, hyperplasia and carcinoma and a change in volume is also evident. Estimation of volume of prostate may be useful in a variety of clinical settings. A cross-sectional descriptive study was designed to see the changes in volume of the prostate with advancing age and done in the Department of Anatomy, Dhaka Medical College, Dhaka from August 2006 to June 2007. The study was performed on 70 post-mortem human prostates collected from the unclaimed dead bodies that were under examination in the Department of Forensic Medicine, Dhaka Medical College, Dhaka. The samples were divided into three age groups; group A (10-20 years), group B (21-40 years) and group C (41-70 years). Volume of the sample was measured by using the ellipsoid formula. The mean ± SD volume of prostate was 7.68 ± 3.64 cm3 in group A, 10.61 ± 3.99 cm3 in group B and 15.40 ± 6.31 cm3 in group C. Mean difference in volume between group A and group C, group B and group C were statistically significant (p<0.001). Statistically significant positive correlation was found between age and volume of prostate (r = + 0.579, p < 0.001). Key Words: Prostate; volume; Bangladeshi. DOI: 10.3329/imcj.v4i2.6501Ibrahim Med. Coll. J. 2010; 4(2): 74-77


2020 ◽  
Vol 22 (3) ◽  
pp. 141-145
Author(s):  
Krishna Chandra Devkota ◽  
S Hamal ◽  
PP Panta

Pleural effusion is present when there is >15ml of fluid is accumulated in the pleural space. It can be divided into two types; exudative and transudative pleural effusion. Tuberculosis and parapneumonic effusion are the common cause of exudative pleural effusion whereas heart failure accounts for most of the cases of transudative pleural effusion. This study was a hospital based cross sectional study performed at Nepal Medical College during the period of January 2016-December 2016. A total of 50 patients who fulfilled the inclusion criteria were enrolled. Pleural effusion was confirmed by clinical examination and radiology. After confirmation of pleural effusion, pleural fluid was aspirated and was analysed for protein, LDH, cholesterol. The Heffner criteria was compared with Light criteria to classify exudative or transudative pleural effusion. Among 50 patients, 30 were male and 20 were female. The mean age of patient was 45.4±21.85 years. The sensitivity and specificity of using Light criteria to detect the two type of pleural effusion was 100% and 90.9%, whereas using Heffner criteria was 94.87%, 100% respectively(P<0.01). There are variety of causes for development of pleural effusion and no one criteria is definite to differentiate between exudative or transudative effusion. In this study Light criteria was more sensitive whereas Heffner criteria was more specific to classify exudative pleural effusion. Hence a combination of criteria might be useful in case where there is difficulty to identify the cause of pleural effusion.


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