scholarly journals PHARMACEUTICO-ANALYTICAL STUDY OF MALATYADI TAILA

2021 ◽  
Vol 9 (11) ◽  
pp. 2729-2735
Author(s):  
Yaramala Chetana ◽  
Sridurga Ch.

Analytical study of Ayurvedic preparations is the need of the present scientific era. Though the Ayurvedic drugs are time tested and have been used successfully in the management of various ailments it is now necessary to prove their quality, efficacy and safety to the scientific world through various modern analytical parameters. The Sneha Kalpa is par excellent to other dosage forms due to their wider advantages like increased absorption and extraction of fat-soluble active principles Sneha Kalpa is the only dosage form that can be administered conveniently both internally as well as externally. Malatyadi Taila is an important herbal formulation mentioned in Chakradutta for the management of the disease Darunaka. Dandruff is an irritative disease of the scalp in which shedding of dead tissue from the scalp with itching sensation is the cardinal feature. It can be correlated to Darunaka the cardinal symptoms of the disease Darunaka are Kandu (itching), Kesha Chyuti (falling of hair), Swapa (abnormalities of touch sensation), Rukshata (roughness or dryness of the skin) and Twak Sputana (breaking or cracking of the skin). Chakradutta has mentioned the application of Malatyadi Taila in the treatment of Darunaka. An attempt has been made in the present study to prepare Malatyadi Taila and standardise it through analytical parameters like organoleptic properties, refractive index, acid value, saponification value, iodine value, loss on drying for developing standards. All the parameters were found to be good and within the standards. Keywords: analytical standardization, Malatyadi Taila, saponification value, HPTLC.

2021 ◽  
Vol 10 (4) ◽  
pp. 117-121
Author(s):  
Chandekar Deepali Boudhadas ◽  
Pawade Uday Venkatrao ◽  
Nikam Ashwin Vithalrao ◽  
Anjankar Meghsham Pramodrao

Analytical study of Ayurvedic formulation is the need of present scientific era. Though the Ayurvedic drugs are time tested and have been used successfully in the management of various ailments, it is now necessary to prove their quality, efficacy and safety to the scientific world through various parameters. Agadtantra is a branch of Ayurveda dealing with classification, mode of action, clinical manifestations and treatment of various poisons. Arka (Calotropis procera) is included in Upavisha by Rasatarangini. Arka Kshara is an alkaline preparation of Upavisha Arka (Calotropis procera) described in treating many disorders. Till date no data is available regarding analytical profile of Arka Kshara. So, the present study is planned to prepare Arka Kshara and develop its analytical profile. These findings will be useful in establishing quality control standards and standardization of Arka Kshara in future.


2021 ◽  
Vol p5 (02) ◽  
pp. 2663-2670
Author(s):  
Deepti Negi ◽  
Anoop Kumar Singh ◽  
Vipin Kumar ◽  
Shweta G. Shukla

Having a healthy and flake free scalp is a great part of hair health. Dandruff can be a very common aliment to reduce our scalp health. If ones want to take care of his/her hair and scalp, oiling is the best thing. Herbal oils are now-a-days widely used by the people because less or no side effects. The present work was aimed to formulate Maltyadi Tail oil for antidandruff purpose (application in Hair and scalp) and was evaluated analytical study. The organoleptic parameters are appearance, color, touch and odor. The physicochemical parameters are Solubility test, Viscosity test, pH, Acid value, Peroxide value, Iodine value, Saponification value, Volatile matter, Ester value, TLC and Test for heavy / toxic metals. The result of the study showed that Maltyadi Tail fulfills all the criteria for ideal hair oil.


2019 ◽  
Author(s):  
Chem Int

The physicochemical properties of six imported and one locally produced edible vegetable oils (soybean oil, sunflower oil, sunlit oil, hayat oil, avena oil, USA vegetable oil and Niger oil) purchased from Bahir Dar city, Ethiopia, were examined for their compositional quality. All the oil samples were characterized for specific gravity, moisture content, color, relative viscosity, refractive indices, ash content, peroxide value, saponification value, smoke point, acid value, free fatty acid value and trace metals contents using established methods. The result clearly indicates that some of the oil samples exhibited unacceptable value when compared with physicochemical parameters recommended by the Codex Alimentations Commission of FAO/WHO and the specification of Ethiopian standards. The contents of nickel (Ni), copper (Cu) and iron (Fe) in seven samples were determined using ICP-OES and their concentrations were found in the range of 1.8-20.4, 45.8-82.2 and 136.04-445.0 mg/kg, respectively.


2020 ◽  
Vol 11 (4) ◽  
pp. 754-758
Author(s):  
Sangita Kamaliya ◽  
Vaghela D B ◽  
Harisha C R ◽  
Shukla V J

Background: Durvadi Ghrita is a Sneha Kalpana which is claimed to be effective in Madhumehajanya Timira (Diabetic Retinopathy).  In present study, it has been used for Nasya. Objective: Present study was planned to look out on herbal drugs used in the preparation of Durvadi Ghrita and standardization of drug by pharmacognostical and physicochemical parameters and HPTLC evaluation. Methods: Identification and authentication of all the raw drug was done by pharmacognostical study i.e. morphological characters, organoleptic characters and powder microscopy. Physicochemical evaluation and HPTLC of final product were done. Results: Pharmacognostical study of all the raw drugs of Durvadi Ghrita showed presence of oil globule, prismatic crystals of Durva. Lignified branched trichome, pollen grains of Utpala Kinjalaka. Trichome, border pitted vessels of Manjishtha. Collenchyma cells, border pitted vessel of Elvaluka. Lignified fibres, oil globules of Sita. Pitted fibres, pitted vessels of Usheera. Scalariform vessels, prismatic crystals of Musta. Pitted vessels and lignified fibres, crystal fibres of Chandana. Lignified cork, and stone cells of Padmaka etc. Pharmaceutical evaluation of Durvadi Ghrita showed results Specific Gravity 0.9125, Refractive Index 1.47, Acid Value 0.4608, Iodine Value 11.45 and Saponification Value 128.856. High Performance Thin Layer Chromatography, 12 spots were found at 254 nm and five spots were found at 366 nm. Conclusion: Identification and authentication of herbal drug used in the preparation of Durvadi Ghrita has been done. Pharmacognostical and physicochemical evaluation of prepared drug has been carried out which can be further useful for standardization of Durvadi Ghrita and other clinical researches.


2020 ◽  
Vol 7 (3) ◽  
pp. 581-586
Author(s):  
Aparna Yadav ◽  
◽  
Sudhakar Prasad Mishra ◽  
P. S. Kendurkar ◽  
Ajay Kumar ◽  
...  

The physiocochemical properties of Jatropha curcas kernel oils were characterized as potential biodiesel, including oil yield per plant, seed oil content, kernel oil content, acid value, iodine value, saponification value and cetane number. Twenty-five accessions of Jatropha curcas were used for oil content measurement sranging from 21.14 to 40.66 %with a mean value of 32.85% and Kernels oil 48.59 to 60.45 % with a mean value of 56.28 %. The seed index ranged significantly from a seed weight of 45.45 to 64.45 g. Oil yields per plant ranged from 0.44 to 2.85 kg with a mean value of 1.70 kg per plant, respectively. To understand the properties of acid value, iodine value, saponification and cetane number, experimental physio-chemical studies were performed. Since these properties are critical for determining the current oil condition. The current study confirms that accession seeds performed higher than international saponification value, iodine value and cetane number standards may be an important source for meeting potential energy requirements.


2021 ◽  
Vol 4 (1) ◽  
pp. 059-066
Author(s):  
Azuaga TI ◽  
Azuaga IC ◽  
Okpaegbe UC ◽  
Ibrahim AI ◽  
Manasseh CK

Soxhlet extraction of oil from seeds of Vitelleria paradoxa was carried out using n-hexane as the solvent. Standards methods were adopted in the analysis of the physiochemical properties; moisture content, melting point, total ash content, pH, specific gravity, iodine value, saponification value, acid value, free fatty acid value and ester value were all evaluated. The oil recovery rate was good with 32.6% yield, moisture content of 3.1%, melting point of 52oC and pH 5.7. Total ash content was 50.3%, specific gravity of 0.9 g/cm3, iodine value 39 mg/L, saponification value 224.6 mgKOH/g, acid value 59.9 mgKOH/g free fatty acid (FFA) 29.9 mgKOH/L and ester value 164.7 mg/L. The results shows that oil from Vitelleria paradoxa seed holds the potentials for wider applications in foods, cosmetics, pharmaceuticals, lubricants and soap making.


2021 ◽  
Vol 9 (7) ◽  
pp. 1334-1343
Author(s):  
Anagha. V. G ◽  
Vikram. S

Avartana is a unique concept mentioned for Sneha Kalpana. The more the number of Avartana the more potent will be the formulation. “Shata Paka Madhuka Taila" is one such formulation that is explained in Charaka Chikitsa Vataraktha Adhikara. Samples were subjected to pharmaceutico - Analytical study to compare the probable changes that would have happened pharmaceutically & analytically. Shata paka Madhuka Taila was prepared as per reference & samples were Analysed. The change in the organoleptic characters of all the Avartita samples was noted. Consistency of taila to semisolid consistency of ghruta in proceeding Avartana was observed. A slight increase in specific gravity & Refractive index were noted, decrease in acid value & iodine value was observed. Rancidity test passed & peroxide value was nil. slight acidic pH was noted. The presence of more bands with different Rf values was seen towards 50th, 75th & 100th Avartita samples on TLC. Pharmaceutical procedure reveals that concentration of the Active bio constituents of yastimadhu & milk fat gets increased in each Avartana., And it was evident from organoleptic characters like conversion of liquid Consistency of taila to semisolid consistency of ghruta (on cooling) in proceeding Avartana. A slight increase in specific gravity & Refractive index suggests more active constituents, decrease in acid value & iodine value suggests products are more stable & less chance of rancid on successive avartana. Rancidity & peroxide value tells product are not rancid. pH changes indicate slight acidicnature & may be irritant due to high potency. TLC shows the presence of more bands towards 50th, 75th& 100th avarti samples shows more active constituents. Hence Avartana process helps for potentiating the formulation by adding active constituents. Keywords: Sneha Kalpana, Avartana, Shata Paka Madhuka Taila.


INDIAN DRUGS ◽  
2012 ◽  
Vol 49 (04) ◽  
pp. 39-42
Author(s):  
M. S Kale ◽  
◽  
K. S. Laddha

Fixed oil obtained from the seeds of Momordica tuberosa (Roxb) Cogn. fruits (family: Cucurbitaceae) was analyzed using GC-MS. Five compounds, namely palmitic acid (hexadecanoic acid), oleic acid (9-octadecenoic acid), stearic acid (octadecanoic acid), ?-eleostearic acid (9, 11, 13-octadecatrienoic acid) and gama-linolenic acid (6, 9, 12-octadecatrienoic acid) were found to be major compounds in fixed oil obtained from the seeds of M. tuberosa fruits. Physical constants saponification value, unsaponifiable matter and acid value were found to be 182.4, 1.56% w/w and 11.44 respectively.


1935 ◽  
Vol 8 (4) ◽  
pp. 604-612
Author(s):  
Hidemaro Endô

Abstract (1) For the determination of the saponification value of the acetone extract, 20 cc. 0.2 N alcoholic potash is added to the extract and the flask is heated on a water bath for 60 minutes. It is then titrated with 0.1 N HCl solution, using phenolphthalein as indicator. (2) When the saponification values of the acetone extracts of 8, 16, and 24 hours are compared, the saponification value of the 8 hour extract is seen to be high, while those of 16 and 24 hour extracts are low. This indicates (a) that the 8 hour extract contains a higher percentage of saponifiable matter than the 16 and 24 hour extracts; (b) the quantity of rubber hydrocarbon which is dissolved in the acetone extract increases with increasing time of extraction, and (c) the acid value of the acetone extract decreases during the period of extraction from 16 to 24 hours. (3) Regarding the saponification values (R) of the acetone extracts of 8, 16, and 24 hours, similar remarks may be made as in (2) above.


2013 ◽  
Vol 8 (3) ◽  
pp. 1934578X1300800 ◽  
Author(s):  
Rachael Dangarembizi ◽  
Eliton Chivandi ◽  
Kennedy Erlwanger

Aloe ferox is an important medicinal plant in Southern Africa whose seeds could be useful as a source of oil. The fatty acid composition of A. ferox seed oil was determined using gas chromatography. The physicochemical properties of the oil were analysed using standard methods. The seeds yielded 19.4% of a light textured oil using the Blight and Dyer's method and 12.3% using the Soxhlet extraction method. The saponification value of the seed oil was 241.9 mg KOH/g and the peroxide value was 8.9 meq/kg. The acid value of the seed oil was 51.5 mg KOH/g (25.9% free fatty acids). The major fatty acids found in the seed oil were linoleic acid (71.8%), oleic acid (12.0%), palmitic acid (11.2%) and stearic acid (2.9%). The results obtained suggest that as A. ferox seed oil is high in linoleic acid, it could be potentially exploited in the cosmetic and pharmaceutical industries.


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