scholarly journals Exercise Intensity and Postprandial Lipemia (La intensidad del ejercicio y la lipemia postprandial)

Retos ◽  
2015 ◽  
pp. 206-212
Author(s):  
Laurel A. Littlefield ◽  
Peter W. Grandjean
Keyword(s):  
Cardiovascular Disease ◽  
Aerobic Exercise ◽  
Exercise Intensity ◽  
Postprandial Lipemia ◽  
High Fat ◽  
Post Exercise ◽  
Increased Risk ◽  
Síndrome Metabólico ◽  
Fat Meal

Exaggerated postprandial lipemia has been observed in metabolic and cardiovascular diseases and is associated with increased risk for cardiovascular disease (CVD). Prior aerobic exercise reduces the triglyceride response to a high-fat meal. The purpose of this review is to examine the factors contributing to metabolic dyslipidemia and to review available evidence supporting the role of aerobic exercise in reducing postprandial lipemia. The contribution of exercise intensity and excess-post exercise oxygen consumption (EPOC) to changes in postprandial lipemia is examined.Key words. lipemia, Metabolic Syndrome, exercise, EPOC.Resumen. La exagerada lipemia postprandial exagerada ha sido observada en enfermedades metabólicas y cardiovasculares, y está asociada a un mayor riesgo de enfermedad cardiovascular (ECV). Se ha encontrado que el ejercicio aeróbico previo reduce la respuesta de los triglicéridos a una comida rica en grasas. El propósito de esta revisión es examinar los factores que contribuyen a la dislipidemia metabólica y revisar la evidencia disponible que respalda el papel del ejercicio aeróbico en la reducción de la lipemia postprandial. Se examina la contribución de la intensidad del ejercicio y el exceso de consumo de oxígeno post-ejercicio (EPOC) en los cambios en la lipemia postprandial.Palabras claves. lipemia, Síndrome Metabólico, ejercicio, EPOC

Effect Of Exercise Intensity On Postprandial Lipemia And Oxidative Stress Markers After A High-fat Meal

2016 ◽  
Vol 48 ◽  
pp. 818-819
Author(s):  
Renata L. Krüger ◽  
Bruno C. Teixeira ◽  
Juliano B. Farinha ◽  
Rodrigo C. O. Macedo ◽  
Gabriel A. Fonseca ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Exercise Intensity ◽  
Postprandial Lipemia ◽  
Oxidative Stress Markers ◽  
High Fat ◽  
Stress Markers ◽  
And Oxidative Stress ◽  
Fat Meal

Correction: Effect of exercise intensity on postprandial lipemia, markers of oxidative stress, and endothelial function after a high-fat meal

2020 ◽  
Vol 45 (12) ◽  
pp. 1400-1400
Author(s):  
Renata Lopes Krüger ◽  
Bruno Costa Teixeira ◽  
Juliano Boufleur Farinha ◽  
Rodrigo Cauduro Oliveira Macedo ◽  
Francesco Pinto Boeno ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Endothelial Function ◽  
Exercise Intensity ◽  
Postprandial Lipemia ◽  
High Fat ◽  
Correction Effect ◽  
Markers Of Oxidative Stress ◽  
Fat Meal

Aerobic Exercise Improves Postprandial Inflammatory and Hemostatic Markers After a High-Fat Meal: A Randomized Cross-Over Study

2020 ◽  
Author(s):  
Bruno Costa Teixeira ◽  
Renata L. Krüger ◽  
Juliano Boufleur Farinha ◽  
Francesco P Boeno ◽  
Rodrigo Cauduro Oliveira Macedo ◽  
...  
Keyword(s):  
Aerobic Exercise ◽  
Exercise Intensity ◽  
Inflammatory Markers ◽  
Factor Vii ◽  
Moderate Intensity ◽  
High Fat ◽  
Moderate Intensity Exercise ◽  
Postprandial State ◽  
Anti Inflammatory ◽  
Fat Meal

Exercise intensity modulates postprandial lipemia. It is still unknown, however, its effect on hemostatic and pro- and anti-inflammatory markers in the postprandial state. Eleven young males perform a 2-day trial on different conditions: (i) REST: rest for 45 min; (ii) MIE: moderate-intensity exercise; and (iii) HIE: heavy-intensity exercise. Experimental conditions were performed in the evening. On the following morning, blood samples were taken in the fasted state (0 h) and at 1, 3, and 5 h after the consumption of a high-fat meal (HFM). Interleukin-10 (IL-10) levels were higher in the HIE vs. MIE trial at 0 and 1 h (p < 0.033) and IL-10 iAUC was greater in the MIE (p = 0.027) and HIE (p = 0.045) vs. REST. Lower levels of anti-coagulation factor VII (FVII) were observed at 1 h in the MIE condition vs. REST (p = 0.043). In comparison with REST, MIE improved hemostatic (FVII) and anti-inflammatory markers (IL-10 iAUC) whereas HIE enhanced IL-10 in the postprandial state. Regardless of the exercise intensity, aerobic exercise mitigates the deleterious consequences of an HFM. Novelty Bullets: • Prior aerobic exercise at moderate-intensity attenuates next day’s postprandial FVII and IL-10 levels whereas exercise performed at heavy-intensity increases IL-10 levels. • Moderate-intensity exercise may be more beneficial to improve hemostatic (FVII) and anti-inflammatory (IL-10) responses while heavy-intensity exercise may improve anti-inflammatory (IL-10) levels only.

scholarly journals Regulatory Role of Sex Hormones in Cardiovascular Calcification

2021 ◽  
Vol 22 (9) ◽  
pp. 4620
Author(s):  
Holly J. Woodward ◽  
Dongxing Zhu ◽  
Patrick W. F. Hadoke ◽  
Victoria E. MacRae
Keyword(s):  
Cardiovascular Disease ◽  
Sex Differences ◽  
Sexual Dimorphism ◽  
Aortic Stenosis ◽  
Sex Hormones ◽  
Sex Hormone ◽  
Increased Risk ◽  
Male Sex ◽  
Primary Male

Sex differences in cardiovascular disease (CVD), including aortic stenosis, atherosclerosis and cardiovascular calcification, are well documented. High levels of testosterone, the primary male sex hormone, are associated with increased risk of cardiovascular calcification, whilst estrogen, the primary female sex hormone, is considered cardioprotective. Current understanding of sexual dimorphism in cardiovascular calcification is still very limited. This review assesses the evidence that the actions of sex hormones influence the development of cardiovascular calcification. We address the current question of whether sex hormones could play a role in the sexual dimorphism seen in cardiovascular calcification, by discussing potential mechanisms of actions of sex hormones and evidence in pre-clinical research. More advanced investigations and understanding of sex hormones in calcification could provide a better translational outcome for those suffering with cardiovascular calcification.

scholarly journals Plasma Branched-Chain Amino Acids and Incident Cardiovascular Disease in the PREDIMED Trial

2016 ◽  
Vol 62 (4) ◽  
pp. 582-592 ◽  
Author(s):  
Miguel Ruiz-Canela ◽  
Estefania Toledo ◽  
Clary B Clish ◽  
Adela Hruby ◽  
Liming Liang ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Amino Acids ◽  
Cardiovascular Death ◽  
Branched Chain Amino Acids ◽  
Control Group ◽  
Cvd Risk ◽  
Hazard Ratios ◽  
Increased Risk ◽  
Branched Chain

Abstract BACKGROUND The role of branched-chain amino acids (BCAAs) in cardiovascular disease (CVD) remains poorly understood. We hypothesized that baseline BCAA concentrations predict future risk of CVD and that a Mediterranean diet (MedDiet) intervention may counteract this effect. METHODS We developed a case-cohort study within the Prevención con Dieta Mediterránea (PREDIMED), with 226 incident CVD cases and 744 noncases. We used LC-MS/MS to measure plasma BCAAs (leucine, isoleucine, and valine), both at baseline and after 1 year of follow-up. The primary outcome was a composite of incident stroke, myocardial infarction, or cardiovascular death. RESULTS After adjustment for potential confounders, baseline leucine and isoleucine concentrations were associated with higher CVD risk: the hazard ratios (HRs) for the highest vs lowest quartile were 1.70 (95% CI, 1.05–2.76) and 2.09 (1.27–3.44), respectively. Stronger associations were found for stroke. For both CVD and stroke, we found higher HRs across successive quartiles of BCAAs in the control group than in the MedDiet groups. With stroke as the outcome, a significant interaction (P = 0.009) between baseline BCAA score and intervention with MedDiet was observed. No significant effect of the intervention on 1-year changes in BCAAs or any association between 1-year changes in BCAAs and CVD were observed. CONCLUSIONS Higher concentrations of baseline BCAAs were associated with increased risk of CVD, especially stroke, in a high cardiovascular risk population. A Mediterranean-style diet had a negligible effect on 1-year changes in BCAAs, but it may counteract the harmful effects of BCAAs on stroke.

scholarly journals Association between Risk Factors for Vascular Dementia and Adiponectin

2014 ◽  
Vol 2014 ◽  
pp. 1-13 ◽  
Author(s):  
Juhyun Song ◽  
Won Taek Lee ◽  
Kyung Ah Park ◽  
Jong Eun Lee
Keyword(s):  
Risk Factors ◽  
Cardiovascular Disease ◽  
Signal Transduction ◽  
Vascular Dementia ◽  
Case Control ◽  
Case Control Studies ◽  
Insulin Signal Transduction ◽  
Increased Risk ◽  
The Brain

Vascular dementia is caused by various factors, including increased age, diabetes, hypertension, atherosclerosis, and stroke. Adiponectin is an adipokine secreted by adipose tissue. Adiponectin is widely known as a regulating factor related to cardiovascular disease and diabetes. Adiponectin plasma levels decrease with age. Decreased adiponectin increases the risk of cardiovascular disease and diabetes. Adiponectin improves hypertension and atherosclerosis by acting as a vasodilator and antiatherogenic factor. Moreover, adiponectin is involved in cognitive dysfunction via modulation of insulin signal transduction in the brain. Case-control studies demonstrate the association between low adiponectin and increased risk of stroke, hypertension, and diabetes. This review summarizes the recent findings on the association between risk factors for vascular dementia and adiponectin. To emphasize this relationship, we will discuss the importance of research regarding the role of adiponectin in vascular dementia.

scholarly journals The Role of Fetuin-A in Disease Processes Prevalent in Postmenopausal Women (El papel de la fetuina A en los procesos de enfermedad prevalentes en mujeres posmenopáusicas)

Retos ◽  
2015 ◽  
pp. 172-179
Author(s):  
Annie A. Bane ◽  
Peter W. Grandjean
Keyword(s):  
Insulin Resistance ◽  
Cardiovascular Disease ◽  
Postmenopausal Women ◽  
Abdominal Fat ◽  
Mineral Density ◽  
Fetuin A ◽  
Increased Risk ◽  
Resistencia A La Insulina ◽  
Low Levels

The purpose of this review is to summarize the role of fetuin-A in disease processes prevalent in postmenopausal women and synthesize effective interventions in obtaining healthy fetuin-A levels. A review of databases for articles related to fetuin-A and diseases associated with postmenopausal women was conducted. Articles were limited to full-text access, published in English since 1944. High fetuin-A levels are closely associated with decreased bone mineral density, increased cardiovascular disease risks, impairment of insulin signaling and disruption of adipocyte functioning. Postmenopausal women have increased risk of osteoporosis, cardiovascular disease, insulin-resistance, intra-abdominal fat accumulation and vascular calcification. Low-levels of fetuin-A have been shown to be protective against the latter. The role of fetuin-A is multi-factorial and the mechanisms in which it is involved in each of these processes are vast. The present body of literature is inconsistent in defining high versus low levels of fetuin-A and their association with healthy-matched controls. The diseases associated with high levels of fetuin-A mimic diseases most prevalent in postmenopausal women. In addition, there is no research, to date, exploring fetuin-A levels in postmenopausal women and the associations it may or may not have in related diseases.Key words: fetuin-A; Alpha2-Heremans-Schmid glycoprotein; cardiovascular disease; and elderly, insulin-resistance, intra-abdominal fat, metabolic syndrome, exercise, weight-loss, calorie restriction and postmenopausal.Resumen. El propósito de esta revisión es sintetizar el papel de la fetuina A en los procesos de enfermedad prevalentes en mujeres posmenopáusicas y resumir las intervenciones efectivas que permiten obtener niveles saludables de fetuina A. Para ello, se revisaron bases de datos con artículos relacionados con fetuina A y las enfermedades asociadas con mujeres posmenopáusicas. La búsqueda de artículos se limitó a aquellos de texto completo publicados en el idioma inglés desde el año 1944. Se encontró que altos niveles de fetuina A están íntimamente relacionados con una reducción de la densidad mineral ósea, un aumento en el riesgo de enfermedad cardiovascular, deterioro de la señalización de la insulina y la alteración del funcionamiento de los adipocitos. Las mujeres posmenopáusicas tienen un mayor riesgo de osteoporosis, enfermedad cardiovascular, resistencia a la insulina, acumulación de grasa intra abdominal y calcificación vascular. Se ha demostrado que niveles bajos de fetuina A son protectores contra esta última condición. El papel de fetuina A es multifactorial y los mecanismos en los que está involucrado en cada uno de estos procesos son muy amplios. El estado actual de la literatura no es consistente en la definición de niveles de fetuina A altos versus bajos y su asociación con controles sanos. Las enfermedades asociadas con altos niveles de fetuina A asemejan las enfermedades más prevalentes en mujeres posmenopáusicas. Además, no existen investigaciones, hasta la fecha, en las que se   exploren los niveles de fetuina A en mujeres posmenopáusicas y las asociaciones que puede o no puede tener en las enfermedades relacionadas.Palabras claves: fetuina A, glicoproteína Alpha2-Heremans-Schmid, enfermedad cardiovascular, adulto mayor, resistencia a la insulina, grasa intra abdominal, síndrome metabólico, ejercicio, pérdida de peso, restricción calórica, posmenopausia.

The impact of acute and chronic exercise on thrombosis in cardiovascular disease

2009 ◽  
Vol 101 (03) ◽  
pp. 452-459 ◽  
Author(s):  
Roxanne Pelletier ◽  
Kim L. Lavoie ◽  
Simon L. Bacon
Keyword(s):  
Cardiovascular Disease ◽  
Aerobic Exercise ◽  
Acute Exercise ◽  
Risk Groups ◽  
Cardiovascular Fitness ◽  
Chronic Exercise ◽  
Warm Up ◽  
Increased Risk ◽  
Intensity Of Exercise ◽  
The Impact

SummaryThere is now a large and impressive literature showing that people who engage in chronic aerobic exercise or who have better cardiovascular fitness levels, tend to live longer and have lower levels of cardiovascular disease (CVD). However, there is a paradox, as acute aerobic exercise has been associated with an increased risk of CVD events. There are now a number of review articles suggesting that the differential benefits of chronic, relative to acute, exercise might be due to thrombotic changes, though the majority of this data is derived from healthy individuals. However, acute exercise is of greater concern and chronic exercise of greater benefit to patient populations. In addition, these higher risk groups tend to present with more complex profiles, e.g. they may be taking medications that influence thrombotic pathways. As such, the current review has focused on newer information relating to exercise, physical activity and thrombosis in patient populations, and highlights some of the growing area’s in the field. For example, the impact of warm-up exercise, the interaction of medications, and issues surrounding the optimal volume and intensity of exercise.

Effects of exercise and n–3 fatty acids on postprandial lipemia

2000 ◽  
Vol 88 (6) ◽  
pp. 2199-2204 ◽  
Author(s):  
Tom R. Thomas ◽  
Brian A. Fischer ◽  
William B. Kist ◽  
Kristen E. Horner ◽  
Richard H. Cox
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Beneficial Effect ◽  
Aerobic Exercise ◽  
Postprandial Lipemia ◽  
Fatty Acid Supplementation ◽  
Acid Supplementation ◽  
Parallel Experiment ◽  
Two Factors ◽  
Fat Meal

Because n–3 fatty acid ingestion and aerobic exercise each has been associated with diminished postprandial lipemia (PPL), the purpose of this study was to evaluate the effect of a combination of these two factors on PPL. Sedentary men underwent a standard dietary preparation, including a 12-h fast before each trial. Six subjects performed a control trial (fat meal, 100 g fat) and an n–3 fatty acid trial (fat meal after 3 wk of n–3 fatty acid supplementation at 4 g/day). In a parallel experiment, six different subjects underwent a control trial and n–3 fatty acid supplementation + 60 min of exercise before ingestion of the fat meal. Supplementation with n–3 fatty acid significantly decreased baseline triglyceride (TG) concentrations but did not significantly affect PPL. The combination of n–3 fatty acid and exercise had no effect on the postprandial TG response. The present study suggests that n–3 fatty acid supplementation lowers resting TG concentrations but inhibits the beneficial effect of aerobic exercise on the postprandial TG response.

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