scholarly journals A Study on the Relationship of Glycaemic Status with Nature of Lesions in Acute Stroke Patients

2021 ◽  
Vol 6 (1) ◽  
pp. 13-20
Author(s):  
Justin Haobam ◽  
Chingakham Arunkumar ◽  
Konjengbam Ghanachandra Singh
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Clinical Outcome ◽  
Blood Glucose Level ◽  
Acute Stroke ◽  
Glucose Control ◽  
Control Group ◽  
Stroke Patients ◽  
Stress Hyperglycaemia ◽  
Stroke Lesion

Background: Stroke in patients of Diabetes Mellitus is a common complication all over the world. The present study was done with the aim to assess the blood glucose level in acute stroke patients of Manipur and find out any correlation with types, size and prognosis of different glycaemic group. Method: The study was a prospective cross-sectional study of all patients who were admitted as acute stroke in Medicine ward, Jawaharlal Nehru Institute of Medical Sciences (JNIMS), Imphal, Manipur. Clinical parameter including History and clinical examination findings were recorded. CT scan of brain, blood glucose level, HbA1c were taken in all the patients. Results: Of 109 patients of acute stroke patients included in the study, 34 were known cases of Diabetes, 10 were newly detected Diabetes cases summing up to a total of 64 cases of Diabetes, 44 of the cases had stress hyperglycaemia and 21 were euglycaemic. Maximum cases consisted of ischaemic strokes (84.4%) and maximum number of haemorrhagic strokes falls under the known diabetes group.None of the euglycaemic patients had any large sized lesions, maximum of them (89.5%) had small sized lesions. Most of the stress glycaemia patients had medium sized strokes while the known diabetes and newly detected diabetes groups had no case of small sized lesion with the maximum large sized lesions occurring in the known diabetes group (78.9%). Clinical outcome was worst in poor glucose control group with 70.3% fatality in this group while maximum clinical improvement was seen in Non-Diabetics (84.6%) consisting of euglycaemia and stress hyperglycaemia groups. Conclusion: There was a good correlation with admission day hyperglycaemia with the size of the stroke lesion in all cases of stroke. The diabetes especially poor glucose control group is associated with increased size of the stroke lesion, severity and poor clinical outcome. Keywords: Stroke, diabetes mellitus, stress hyperglycaemia, euglycaemia.

scholarly journals Nutritional Therapy In Ischemic Stroke Patients With Type 2 Diabetes Mellitus : A Case Report

2020 ◽  
Vol 3 (1) ◽  
pp. 33
Author(s):  
Cipuk Muhaswitri ◽  
Diyah Eka Andayani ◽  
Taufik Mesiano
Keyword(s):  
Diabetes Mellitus ◽  
Ischemic Stroke ◽  
Blood Glucose ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Nutritional Therapy ◽  
Facial Nerve Paralysis ◽  
Stroke Patients ◽  
Nerve Paralysis

<p><strong>Introduction</strong>: The prevalence of stroke in Indonesia increased from 8.3 per 1000 population in 2007 to 12.1 per 1000 population in 2013, based on Riset Kesehatan Dasar (RISKESDAS) 2013. Diabetes mellitus (DM) is an independent risk factor and can be modified. Hyperglycemia that occurs in the acute phase of stroke is associated with an increase in mortality and poor clinical outcome after stroke. Moreover, stroke patients are at risk of developing hypoalbuminemia due to poor intake and the presence of a chronic inflammatory process.<br /><strong>Methods:</strong> A 66-year-old female patient with third recurrent ischemic stroke, history of uncontrolled DM, conciousness based on GCS is E3M5Vaphasia, Nasogastric tube (NGT) was inserted and there was a right facial nerve paralysis and bilateral hemiparesis . Nutritional status of patient is obese-1. During follow up period, the patient's blood glucose level ranged from 194 g/dl-345 g/dl. Nutrition therapy is given with a target of 1350 kcal (32 kcal/kg). Its composition consists of 15% protein, 25% fat and 60% carbohydrate (preferred complex carbohydrates), in the form of DM-specific formula containing inulin and monounsaturated fatty acid (MUFA). This nutritional therapy was administrated six times per day via enteral pathway, followed by the administration of micronutrients of vitamins C, B and folic acid.<br /><strong>Result:</strong> During follow up period, the patient tolerated well with the diet. After the 14 days hospitalization, there was improvement of blood glucose level (&lt;200 g/dL). Albumin level increases from 2.5 g/dL to 2.9 g/dl by the nutritional therapy containing protein more than 1.2 g/kg/day.<br /><strong>Conclusion:</strong> Administering a diet with the recommended composition and formula helps control hyperglycemia and improve hypoalbuminemia in patients that can improve the patient's clinical condition.</p>

scholarly journals Metabolome of Cerebral Thrombi Reveals an Association between High Glycemia at Stroke Onset and Good Clinical Outcome

Metabolites ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. 483
Author(s):  
Laurent Suissa ◽  
Jean-Marie Guigonis ◽  
Fanny Graslin ◽  
Emilie Doche ◽  
Ophélie Osman ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Discriminant Analysis ◽  
Clinical Outcome ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Area Under The Curve ◽  
Stroke Onset ◽  
Stroke Patients ◽  
High Blood Glucose ◽  
High Blood Glucose Level

Despite the fact that glucose is the main fuel of the brain, hyperglycemia at hospital admission is generally associated with a poor functional outcome in stroke patients. This paradox may be explained by the lack of information about the blood glucose level at stroke onset. Here, we analyzed the metabolome of blood cells entrapped in cerebral thrombi to gain insight into their metabolism at stroke onset. Fourty-one consecutive stroke patients completely recanalized by mechanical thrombectomy within 6 h were included. The metabolome of retrieved thrombi was analyzed by liquid chromatography tandem with mass spectrometry. Discriminant Analysis (sparse Partial Least Squares Discriminant Analysis (sPLS-DA)) was performed to identify classification models and significant associated features of favorable clinical outcome at 3 months (modified Rankin Scale (mRS) < 2). sPLS-DA of the metabolomes of cerebral thrombi discriminated between stroke patients with a favorable or poor clinical outcome (Area Under the Curve (AUC) = 0.992 (0.931–1)). In addition, our results revealed that high sorbitol and glucose levels in the thrombi positively correlated with favorable clinical outcomes. Sorbitol, a short-term glycemic index reflecting a high blood glucose level at stroke onset, was found to be an independent predictor of good outcome (AUC = 0.908 (0.807–0.995)). This study demonstrates that a high blood glucose level at stroke onset is beneficial to the clinical outcome of the patient.

scholarly journals Effect of Baluran Gum Arabic on Blood Glucose Level in Diabetic Rat (Rattus Novergicus )

2021 ◽  
Vol 9 (2) ◽  
pp. 81
Author(s):  
Hidayat Teguh Wiyono ◽  
Eva Tyas Utami ◽  
Dinna Wahyu Putri Wardhani
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Gum Arabic ◽  
Diabetic Rat ◽  
Control Group ◽  
Normal Range ◽  
Reduce Blood Glucose ◽  
Reduce Blood Glucose Level

Diabetes mellitus is a metabolic disease which indicated with increasing blood glucose level. Carbohidrate, protein, mineral and secondary metabolite (alkaloid, tannin and saponin) can be benefical to treat diabetes mellitus. Rats were randomly divided into three groups. First, control group. Second, STZ group, untreated diabetic. Third, STZ+GA 15% group, diabetic treated with GA 15%. Result showed that blood glucose level before STZ induction on control and STZ group within normal range 78,57±11,90 mg/dL and 74,85±6,86 mg/dL. Blood glucose level significantly increase after STZ induction on STZ and STZ+GA 15% group become 375±6,53 mg/dL and 346,42±50,23 mg/dL. Diabetic rat treated with GA 15% revealed decrease in blood glucose level compared to untreated diabetic rat. Blood glucose level on STZ+GA 15% group continuously decrease become 96,42±13,45 mg/dL and 82,14±9,19 mg/dL. In conclusion, GA 15% could reduce blood glucose level on diabetic rat.

scholarly journals Effect of Ethanolic Extract of Swietenia mahagoni Seeds on Experimentally Induced Diabetes Mellitus in Rats

1970 ◽  
Vol 6 (2) ◽  
pp. 70-73 ◽  
Author(s):  
SMM Mahid-Al-Hasan ◽  
MI Khan ◽  
BU Umar
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Blood Glucose Level ◽  
Beta Cells ◽  
Ethanolic Extract ◽  
Diabetic Rats ◽  
Control Group ◽  
Group D ◽  
Swietenia Mahagoni ◽  
Experimentally Induced

Diabetes mellitus is a heterogeneous group of syndromes characterized by an elevation of blood glucose caused by a relative or absolute deficiency of insulin. The incidence of diabetes is growing rapidly worldwide. Drug treatment for diabetes mellitus is expensive and carries risks for many adverse effects. Bangladesh is a rich emporium of medicinal plants useful in the treatment of diabetes. The study was performed to investigate the blood glucose lowering effect of Swietenia mahagoni seeds in experimentally induced diabetic rats. Twenty four healthy Long Evans Norwegian strain of rats were included in the study and divided into four groups (A, B, C and D) comprising 6 rats each. Diabetes was induced by alloxan (120 mg/kg body weight). Administration of ethanolic extract of Swietenia mahagoni seeds (group-B) produced no significant change in the blood glucose level as compared to control (group-A). Administration of ethanolic extract of Swietenia mahagoni seeds in group-D produced a significant reduction in blood glucose level as compared to diabetic control (group-C). Histological examination of pancreas showed destruction of beta cells in Islets of pancreas in group-C whereas retaining of islets and few degranulations of beta cells of pancreas found in group-D. These observations and results provide information that ethanolic extract of Swietenia mahagoni seeds has hypoglycaemic effect in experimentally induced diabetic rats which requires further investigation. Key words: Diabetes mellitus; Swietenia mahagoni; Alloxan; Rat; Blood glucose. DOI: http://dx.doi.org/10.3329/fmcj.v6i2.9203 FMCJ 2011; 6(2): 70-73

scholarly journals Pengaruh Pemberian Sagu (Metroxylon spp) terhadap Kadar Glukosa Darah Mencit Putih Jantan (Mus musculus) Diabetes Melitus

2018 ◽  
Vol 8 (2) ◽  
pp. 193
Author(s):  
Wilda Laila
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Mus Musculus ◽  
Rice Flour ◽  
Control Group ◽  
P Value ◽  
Standard Diet ◽  
Significant Difference

Diabetes Mellitus (DM) causes various complications if it is not controlled properly. International Diabetes Federation (IDF, 2015) stated that the prevalence DM in 2014 were 8, 3% or equals to 387 million in the world. The objective of this research was to identify the influence of Sago (Metroxylon spp) on blood glucose levels of male white mouse (Mus musculus) with Diabetes Mellitus. This research was an experimental research with pre-test and post-test only group design, conducted from October to December 2016. The samples were twentyfive male white mice (Mus musculus) what were divided into five groups such as : negative control group was given standard diet, the positive control group was given induction of alloxan, three treatment groups (P1) 65mg/20g BW/day was given rice flour, groups (P2) 65mg/20g BW/day was given sago and P3 group was given sago 130mg/20g BW/day. The data were analyzed by Anova testing and Post Host Test testing with trust degree of 95%. The result was the blood glucose level of the mice showed that there was a significant difference with p value 0,012 on group (P2) with treatment, while in group treatment (P3), there was also significant difference with p value 0,019. It could be concluded that there was a significant difference in the average blood glucose level after the rice flour and sago treatment towards various groups.  Keyword : Sago, Rice Flour, Blood Glucose Level, and Diabetes Mellitus

scholarly journals Penerapan Modifikasi Psikoedukasi Pada Penderita Diabetes Mellitus Tipe2

2018 ◽  
Vol 6 (2) ◽  
pp. 147
Author(s):  
Nailiy Huzaimah
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Blood Glucose Level ◽  
Family Support ◽  
Glucose Level ◽  
Self Efficacy ◽  
Diabetes Management ◽  
Self Management ◽  
Control Group ◽  
Control Group Design

Controlled blood glucose level is one of the success indicator of the diabetes management. A good comprehension, high self-efficacy, and good family support is needed to encourage and strengthen the effort of individuals to achieved good behavioral diabetes self-management, which helped to control blood glucose level. This study aimed to determine the Psychoeducation Modification’s effects on comprehension, self-efficacy, family support, behavioral diabetes self-management, and blood glucose level of people with type 2 diabetes mellitus (T2DM). This study used pre and post test control group design. Respondents of this research are population with T2DM and their families who are undergoing outpatient treatment at Internal Medicine Outpatient Unit of Dr. H. Moh. Anwar Sumenep Hospital (n = 40). Collecting data included the patients comprehension, self-efficacy, behavioral self-management of diabetes, family support, and random blood glucose level. Data collection used questionnaires and the laboratory test of blood glucose level, then analyzed by a different test with the α value

scholarly journals Pengaruh Relaksasi Terhadap Penurunan Kadar Gula Darah Pada Pasien Diabetes Mellitus Tipe 2 di Sebuah Rumah Sakit di Tasikmalaya

2008 ◽  
Vol 12 (2) ◽  
pp. 108-114
Author(s):  
Asep Kuswandi ◽  
Ratna Sitorus ◽  
Dewi Gayatri
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Nursing Intervention ◽  
T Test ◽  
Control Group ◽  
Before And After ◽  
And Control

AbstrakTeknik relaksasi dapat menurunkan kadar gula darah pasien melalui penurunan stres. Penelitian ini bertujuan mengetahui perbedaan kadar gula darah pasien diabetes mellitus sebelum dan sesudah relaksasi di salah satu rumah sakit di Tasikmalaya, Jawa Barat. Penelitian ini merupakan penelitian kuantitatif dengan desain kuasi eksperimen menggunakan kontrol. Sampel berjumlah 100 responden, terdiri dari masing-masing 50 responden pada kelompok intervensi kontrol. Perbedaan kadar gula darah sebelum dan sesudah latihan relaksasi dengan diuji dengan paired-sample T test. Hasil menunjukkan terjadi penurunan kadar gula darah Rerata sebesar 53,6 mg/dL sesudah relaksasi, dengan nilai p = 0,000. Angka penurunan tertinggi terjadi pada hari ketujuh relaksasi dan angka terendah terjadi pada hari ketiga. Penelitian ini menyimpulkan relaksasi dapat menurunkan kadar gula darah pasien diabetes mellitus. AbstractRelaxation is a basic nursing intervention of to decrease the blood glucose level of diabetes mellitus patients. The aim of this study was to compare blood glucose level before and after relaxation on the experiment and control group of type 2 diabetes mellitus patients at a hospital in Tasikmalaya, West Java. This quasi experiment study with control group involved 100 participants, divided equally into the experiment and control group. Fifty participants were trained the relaxation technique whilst the control group didn’t. The difference of blood glucose level before and after relaxation was examined by the pairedsample T test. The blood level serum were significantly decreased about 53,6 mg/dL after relaxation with p value 0,000. The decreasing rate reached its highest on seventh day after relaxation whereas the lowest was on the third day after relaxation. In conclusion, relaxation can decrease the blood glucose level of the diabetic mellitus type 2 patients.

scholarly journals Investigation on Blood Glucose Control Nursing of ICU Severe Patients

2020 ◽  
Vol 4 (6) ◽  
Author(s):  
Shoutao Guo
Keyword(s):  
Blood Glucose ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Clinical Data ◽  
Sofa Score ◽  
Glucose Control ◽  
Blood Glucose Control ◽  
Control Group ◽  
Observation Group ◽  
The Difference

Objective: To analyze the effect of blood glucose control nursing in intensive care unit (ICU) patients. Methods: The clinical data of 70 severe patients in ICU of our hospital from January 2019 to May 2020 were retrospectively analyzed. The clinical data of 34 patients with routine intervention were divided into the control group, and the clinical data of 36 patients with routine intervention and blood glucose control nursing were divided into the observation group, all were intervened for 14 days. The blood glucose levels and prognosis of the two groups were compared before intervention and at the end of 14 days of intervention, the time required to achieve the standard blood glucose level of the two groups was recorded. Results: After 14 days of intervention, the fasting blood glucose level of the observation group was lower than the control group, the difference was statistically significant (P < 0.05); the time of blood glucose reaching the standard in the observation group was shorter than that in the control group, the difference was statistically significant (P < 0.05); on the 14th day of intervention, the sequential organ failure assessment score (SOFA) score of the two groups was lower than before intervention, the SOFA score of the observation group was lower than control group, the difference was statistically significant (P < 0.05). Conclusion: The effect of blood glucose control nursing in ICU is better, which effectively controlled the blood glucose level of patients and improved the prognosis of patients.

scholarly journals Effects of intermittently scanned continuous glucose monitoring on blood glucose control and the production of urinary ketone bodies in pregestational diabetes mellitus

2021 ◽  
Vol 13 (1) ◽  
Author(s):  
Shu-ying Li ◽  
Hang Guo ◽  
Yi Zhang ◽  
Pei Li ◽  
Pei Zhou ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Blood Sugar ◽  
Continuous Glucose Monitoring ◽  
Glucose Control ◽  
Ketone Bodies ◽  
Blood Glucose Control ◽  
Glucose Monitoring ◽  
Control Group ◽  
Pregestational Diabetes

Abstract Objective To investigate the effects of intermittently scanned continuous glucose monitoring (isCGM) on blood glucose control, clinical value of blood glucose monitoring and production of urinary ketone bodies in pregestational diabetes mellitus. Method A total of 124 patients with pregestational diabetes mellitus at 12–14 weeks of gestation admitted to the gestational diabetes clinic of our hospital from December 2016 to December 2018 were selected and randomly divided into two groups. Sixty patients adopted self-monitoring of blood glucose (SMBG) were taken as the control group, and the other 64 patients adopted isCGM system by wearing the device for 14 days. Blood sugar control, glycosylated albumin level, ketone production in urine, the maximum and minimum of blood sugar value measured by different monitoring methods and their occurrence time were observed in the two groups. Result (1) No statistically significant differences were found between the groups in terms of maternal age, gestational age at first visit, family history, duration of diabetes, education level, total insulin dose, chronic hypertension, abortion history, nulliparity, assisted reproductive technology, history of macrosomia childbirth, pre-pregnancy BMI, and overweight (%) at the first visit and hypoglycemia, (2) the value of Glycated Albumin was lower in the CGM group compared to the control group at 2ed weeks (14.6 ± 2.2 vs. 16.8 ± 2.7, p < 0.001). The women in the CGM group spent increased time in the recommended glucose control target range of 3.5–7.8 mmol/L (69 ± 10% vs. 62 ± 11%, p < 0.001) and reduced time above target compared with those in the control group at 2 weeks (25 ± 7% vs. 31 ± 8%, p < 0.001). In the second week of the study, the positive rate of urinary ketone body in isCGM group was lower than that in the control group (42 ± 5 vs. 54 ± 5, p < 0.001), and (3) the minimum blood glucose of 31.2% (20/64) cases in isCGM group appeared during 0:00–2:59 at night, and 26.6% (17/64) cases appeared during 3:00–5:59 at night. The minimum values of 40.0% (24/60) cases in the control group appeared within the 30 min before lunch, 23.3% (14/60) within the 30 min before breakfast, and 11.7% (7/60) within the 30 min before dinner. The cases of minimum of blood sugar before meals accounted for 75% of all the minimum values, and the cases of minimum at night only accounted for 8.3%. Conclusion Intermittently scanned continuous glucose monitoring can reduce hyperglycemia exposure and ketone body formation in pregestational diabetes mellitus. In addition, isCGM is better than SMBG in detecting nocturnal hypoglycemia.

scholarly journals Pengendalian status gizi, kadar glukosa darah, dan tekanan darah melalui terapi gizi medis pada pasien diabetes mellitus (DM) tipe 2 rawat jalan di RSU Mataram NTB

2010 ◽  
Vol 7 (2) ◽  
pp. 48
Author(s):  
Suhaema Suhaema ◽  
Ahmad Husain Asdie ◽  
Retno Pangastuti
Keyword(s):  
Diabetes Mellitus ◽  
Blood Pressure ◽  
Blood Glucose ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Nutrition Status ◽  
Control Group ◽  
Nutrition Counseling ◽  
Type 2 Dm

Background: The prevalence of diabetes mellitus (DM) is increasing globally, including in Indonesia. Studies by Diabetes Control and Complication Trial (DCCT) and U.K. Prospective Diabetes Study Group (UKPDS) prove the benefit of medical nutrition therapy (MNT) to glycemic control. Similar studies have not been done much in Indonesia.Objective: To identify the effects of MNT to nutrient intake, control of nutrition status, blood glucose and blood pressure of type 2 DM outpatients.Method: This was a randomized controlled trial. Subject of the study consisted of 60 people. The experiment group got MNT; whereas the control group got conventional nutrition counseling. Data were processed using computer, nutrients were analyzed using nutrisurvey. Statistical t-test was done to identify the effect of intervention.Result: Intake of energy, fat and carbohydrate of the experiment group decreased signifcantly close to the necessity at subsequent decrease as much as -14.05 (p= 0. 009), -35.64 (p=0.019) and -19.14 (p=0.035). Body mass index In the experiment group decreased -0.41kg/m  and waist circumference -0.24cm, where as the control group -0.23 kg/m  and -014cm. Blood glucose level during fasting decreased -23.6 mg/dl in the experiment group and -14.03 mg/dl in the control group (p=0.036). Systolic and dyastolic blood pressure of the experiment group decreased -3.33 mmHg (p=0.035) and 2 2 -1.67 mmgHg (p=0.895), whereas the control group + 0.5 mmHg  and -1.33 mmHg; the change was insignificant.Conclusion: Intake of nutrient, nutrition status, blood glucose level and blood pressure of type 2 DM patients that got MNT was more controllable than of those that got conventional nutrition counseling.

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