scholarly journals Meta-Analysis: The Relationship of Fe Tablet Consumption Adherence and Anemia Prevalence in Pregnant Women

2021 ◽  
Vol 6 (4) ◽  
pp. 23-35
Author(s):  
Muti’ah Ma’rifati Ilma ◽  
Roselina Panghiyangani ◽  
Nia Kania

Anemia in pregnancy is anemia due to iron deficiency. The incidence of anemia in pregnant women ranges from 20% to 89%. As many as 40% of maternal deaths in developing countries are related to anemia in pregnancy and most often occur in developing countries, including Indonesia. In Indonesia, efforts made to overcome the problem of anemia in pregnant women are the administration of iron (Fe) tablets. This study aims to explain and analyse the relationship of adherence to Fe tablet consumption with anemia in pregnant women. This study uses a meta-analysis study. Researchers carried out research data collection by browsing online journals, using the Scopus and Google Scholar databases. In the meta-analysis process using the RevMan (Review Manager) 5.3 application, the results obtained Effect size (In Odds Ratio) of 2.44 (95% CI 1.30-4.60), which means that pregnant women who do not adhere to consuming Fe tablets have a risk 2.44 times affected by anemia compared to obedient pregnant women. There is a significant relationship between consuming Fe tablets and the incidence of anemia in pregnant women. Keywords: adherence, Fe tablets, anemia.

2021 ◽  
Vol 1 ◽  
pp. 1224-1232
Author(s):  
Ade Dian Oktavia ◽  
Emi Nurlaela

AbstractThe Number of Maternal Mortality in Indonesia was highest in 2019 due to bleeding in 1.280 cases. Bleeding can occur due to anemia in pregnancy. Anemia in pregnancy can be said to be a conditions where hemoglobin (Hb) levels are below 11 gr % in the I and III trimesters, while in the II trimester hemoglobin levels are below 10,5 gr %. One of the causes of anemia in pregnancy is a lack of nutrients or malnutritions. To find out the relationship of nutritional status with the incidence of anemia in pregnant women through literature review. This study used literature review method with 6 articles sourced from online database with electronic search on Google Scholar and Garuda Portal published in 2011-2021. Critical study instrument used is using JBI (Joanna Briggs Institute). The result of this study showed that there is a link between nutritional status and the incidences of anemia in pregnant women with the result of p value <0,05. Nutritional status is one of the factors thet can lead to anemia in pregnant women.Keywords: Anemia; nutritional status; pregnant women. AbstrakAngka Kematian Ibu di Indonesia paling tinggi tahun 2019 disebabkan oleh perdarahan sebanyak 1.280 kasus. Perdarahan dapat terjadi karena anemia dalam kehamilan. Anemia dalam kehamilan dapat dikatakan suatu kondisi dimana kadar hemoglobin (Hb) dibawah 11 gr % pada trimester I dan III, sedangkan pada trimester II kadar hemoglobin dibawah 10,5 gr %. Salah satu penyebab anemia dalam kehamilan adalah kurangnya zat gizi atau malnutrisi. Untuk mengetahui hubungan status gizi dengan kejadian anemia pada ibu hamil melalui literature review. Penelitian ini menggunakan metode literature review 6 artikel yang bersumber dari database online dengan penelusuran elektronik pada Google Scholar dan Portal Garuda yang dipublish pada tahun 2011-2021. Instrument telaah kritis yang digunakan yaitu dengan menggunakan JBI (Joanna Briggs Institute). Hasil penelitian literature review dari 6 artikel menunjukkan ada hubungan antara status gizi dengan kejadian anemia pada ibu hamil dengan hasil p value <0,05. Status gizi merupakan salah satu faktor yang dapat mengakibatkan anemia pada ibu hamil.Kata kunci: Anemia; ibu hamil; status gizi.


2019 ◽  
Vol 9 (2) ◽  
pp. 59
Author(s):  
Akhmad Mahyuni ◽  
Nirma Yunita ◽  
Eka Maya Putri

World Health Organization (WHO) data in 2010 noted 40% of maternal deaths in developing countries are associated with pregnancy anemia. Anemia anemia in pregnancy caused by iron deficiency and acute bleeding, even distance mutually interact with each other. Anemia in pregnancy is a major health problem in developing countries with high morbidity in pregnant women. The average pregnancy with anemia in Asia is estimated at 72.6%. The high prevalence of anemia in pregnant women is a problem that is being exposed to the government of Indonesia. Preliminary study results conducted by researchers through physical examination of pregnant women in third trimester, seen from signs of symptoms, as many as 10 people, there are 6 people (60%) who have anemia and 4 people (40%) were not anemic, of 6 people with anemia there were 3 (50%) unsafe parities, 1 person (16.7%) had infectious diseases, and 2 (33.3%) malnourished. The purpose of this study was to determine the relationship of parity, infectious diseases, and nutritional status with anemia status in third trimester pregnant women in the work area of ​​PuskesmasPasalingHulu Sungai Selatan in 2017. The method used was analytical with cross sectional approach. The result of this research are most of respondents who suffer from anemia that is as many as 33 people (67,3%), unsafe parity that is 29 people (59,2%), not enter as many as 34 people (69,4%), as many as 28 people (57.1%). there is a proven to have relationship of parity, nutritional status with anemia status in third trimester pregnant women in work area of ​​Puskesmas PasungkanHulu Sungai Selatan 2017, not proven to have relation of disease with anemia status in third trimester pregnant woman in working area of ​​Puskesmas PasungkanHuluSungai Selatan 2017 Keywords: Status of anemia, parity, infectious diseases, nutritional status


Author(s):  
Mukarromatul Khoiroh ◽  
Nurul Azizah

Postpartum hemorrhage is bleeding that occurs after the birth of the baby, placenta, and 2 hours after the placenta is born. One of the causes is anemia. Research in 2015, 60% of 100 mothers giving birth at RSIA Kirana Taman Sidoarjo experienced postpartum hemorrhage. The aim of the study was to determine the relationship of anemia in pregnancy with the incidence of postpartum hemorrhage in labor mothers. The study design used an analytical survey with a retrospective method. The population of 206 maternity mothers was taken with simple random sampling technique as many as 136 samples in August 2017. Data were analyzed by Chi Square statistical test with 0.05. The results showed that postpartum hemorrhage was more experienced by mothers with anemia (66.7%) than  those without anemia (26.2%). While those who did not experience postpartum hemorrhage were more experienced by mothers who were not anemic (73.8%) than those who were anemic (33.3%). Chi square test results  (p=0.000  <0.05),  which means there is a relationship  of anemia in pregnancy with the incidence of postpartum hemorrhage in labor mothers. Conclusions of the study were the relationship of anemia in pregnancy with the  incidence  of postpartum hemorrhage in labor mothers. It is expected that midwives and doctors conduct early detection of anemia so that appropriate care can be carried out.


2020 ◽  
Vol 6 (2) ◽  
pp. 29-34
Author(s):  
Metha Fahriani ◽  
Sefti Fusvita Sari ◽  
Yuni Ramadhaniati

In 2017 the number of maternal deaths was 28, consisting of 6 maternal deaths, 10 maternal deaths and 12 puerperal maternal deaths. The purpose of this study is to know the relationship of age and parity with the incidence of preeclampsia in pregnant women at dr. M. Yunus Hospital in Bengkulu year 2018. The type of research used is case control. The population in this study were all pregnant women in dr. M. Yunus Hospital in Bengkulu year 2018. The sampling technique was a case sample using total sampling, namely all pregnant women with preeclampsia and control samples using systematic random sampling technique that is sampling using multiples recorded in the hospital register of dr. M. Yunus Hospital in Bengkulu year 2018. The results of this study there is no relationship between age and the incidence of preeclampsia in pregnant women at RSUD dr. M. Yunus in 2018. With the value of p = 0.424> α = 0.05 and the value of Odds Ratio or Risk Estimate = 1.496 and there is a significant relationship between parity and the incidence of preeclampsia in pregnant women at RSUD dr. M. Yunus Bengkulu in 2018. With the value of p = 0.011 <α = 0.05 with the medium category.It is expected that the results of this study can be a program development and service improvement in reducing the prevalence of preeclampsia.


Author(s):  
Astika Candra Nirwana ◽  
◽  
Yulia Lanti Retno Dewi ◽  
Bhisma Murti ◽  
◽  
...  

ABSTRACT Background: Prophylactic oral iron is recommended during pregnancy to meet the increased requirement during the antenatal period. The most commonly used iron preparation for anemia in pregnancy is iron sucrose complex (ISC). The purpose of this study was to compare the effects of ferric carboxymaltose versus iron sucrose on the ferritin level in pregnant women with anemia. Subjects and Method: This was a meta-analysis study. The study was conducted by collecting published articles from 2010 to 2019 in PubMed, Science Direct, and Google Scholar databases. The keywords used to search the articles including “Ferric Carboxymaltose”, “Ferric Carboxymaltose and anemia in pregnancy”, and “the effect of Ferric Carboxymaltose for anemia”. The inclusion criteria was full text with randomized control trial study, anemia therapy provision using ferric carboxymaltose versus iron sucrose, and the study subjects were pregnant women with anemia. The selected articles were analyzed using Revman 5.3. Results: 5 articles that meet the inclusion criteria were selected for this study. There was high heterogeneity between experiment group (I2 = 96%; p= 0.020). Therefore, this study used random effect model. Ferric carboxymaltose provision increased feritin level 0.89 times than iron sucrose (Mean Difference= 0.89; 95% CI= 0.12 to 1.66; p<0.001). Conclusion: Ferric carboxymaltose is effective to increased feritin level in pregnant women. Keywords: ferric carboxymaltose, iron sucrose, randomized controlled trial Correspondence: Astika Candra Nirwana. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir Sutami 36A, Surakarta 57126, Central Java. Email: [email protected]. Mobile: 085640018896 DOI: https://doi.org/10.26911/the7thicph.05.48


2021 ◽  
Vol 49 (1) ◽  
Author(s):  
Felix Bongomin ◽  
Ronald Olum ◽  
Andrew Peter Kyazze ◽  
Sandra Ninsiima ◽  
Gloria Nattabi ◽  
...  

Abstract Background Anemia in pregnancy represents a global public health concern due to wide ranging maternal and neonatal adverse outcomes in all peripartum periods. We estimated the prevalence and factors associated with anemia in pregnancy at a national obstetrics and gynecology referral hospital in Uganda and in addition performed a systematic review and meta-analysis of the overall burden of anemia in pregnancy in Uganda. Methods We conducted a cross-sectional study among 263 pregnant women attending the antenatal care clinic of Kawempe National Referral Hospital, Kampala, Uganda, in September 2020. Anemia in pregnancy was defined as a hemoglobin level of < 11.0 g/dl and microcytosis as a mean corpuscular volume (MCV) of < 76 fL. We also performed a systematic review (PROSPERO Registration ID: CRD42020213001) and meta-analysis of studies indexed on MEDLINE, Embase, African Journal Online, ClinicalTrials.gov, ICTRP, and the Cochrane Library of systematic review between 1 January 2000 and 31 September 2020 reporting on the prevalence of anemia in pregnancy in Uganda. Results The prevalence of anemia was 14.1% (n= 37) (95%CI 10.4–18.8), of whom 21 (56.8%) had microcytic anemia. All cases of anemia occurred in the second or third trimester of pregnancy and none were severe. However, women with anemia had significantly lower MCV (75.1 vs. 80.2 fL, p<0.0001) and anthropometric measurements, such as weight (63.3 vs. 68.9kg; p=0.008), body mass index (25.2 vs. 27.3, p=0.013), hip (98.5 vs. 103.8 cm, p=0.002), and waist (91.1 vs. 95.1 cm, p=0.027) circumferences and mean systolic blood pressure (BP) (118 vs 125 mmHg, p=0.014). Additionally, most had BP within the normal range (59.5% vs. 34.1%, p=0.023). The comparison meta-analysis of pooled data from 17 published studies of anemia in pregnancy in Uganda, which had a total of 14,410 pregnant mothers, revealed a prevalence of 30% (95% CI 23–37). Conclusions Despite our study having a lower prevalence compared to other studies in Uganda, these findings further confirm that anemia in pregnancy is still of public health significance and is likely to have nutritional causes, requiring targeted interventions. A larger study would be necessary to demonstrate potential use of basic clinical parameters such as weight or blood pressure as screening predictors for anemia in pregnancy.


Author(s):  
Noer Saudah

Anemia during pregnancy caused death in the mother and fetus. Husband's support for reduction the risk of anemia during pregnancy was important. The purpose study was to determine relationship husband's support of anemia management with the incidence anemia in pregnant.  Design research used analytic correlation with a cross-sectional. The population were third trimesters  pregnantcy in Mojokerto City. Sample size were 54 pregnant women with purposive sampling. Independent variabel was husband support. Dependent variabel was anemia in pregnant.  Instrument used a questionnaire and Analyse data with spearman rank test. Results showed  the majority had positive support and not anemia, namely 24 respondents (44.4%) while mild support and mild anemia were 15 respondents (25.9%). Spearman rank test p = 0.0002 and  correlation coefficient  0.838. It’s means the relationship between two variables is significant. The correlation between the relationship of husband support with anemic events in pregnant women and the nature of one-way relationships. There is a significant and very strong relationship. Husbands who are able to provide positive support to pregnant women can reduce the risk of anemia during pregnancy. The husband must provide support to wife including giving attention, empathetic, advice,  knowledge so that the risk of anemia in pregnancy decreases


2020 ◽  
Vol 19 ◽  
pp. 153303382096358
Author(s):  
Tao Ye ◽  
Zhangqun Ye

Background: Non-coding RNA-activated by DNA damage (NORAD), a novel identified lncRNA, was found to be aberrantly expressed in various types of cancer. This meta-analysis was performed to evaluate the value of lncRNA NORAD as a prognostic biomarker in human cancers. Methods: We searched PubMed, Web of Science, PMC, and Embase databases thoroughly for eligible literatures. Studies which explored the relationship of lncRNA NORAD expression with clinical outcomes in human cancers were included in our meta-analysis. Review Manager version 5.3 and Stata SE 12.0 were used to perform the data analyses. Results: Our meta-analysis results indicated that cancer patients with high lncRNA NORAD expression tended to have unfavorable overall survival (OS) (HR = 1.67; 95% CI, 1.44-1.95; P < 0.00001). Moreover, elevated lncRNA NORAD expression showed a significant relationship with poor tumor grade (OR = 1.61; 95% CI, 1.01-2.56; P = 0.05) and more lymph node metastasis (LNM) (OR = 2.66; 95% CI, 1.60-4.43; P = 0.0002). Conclusions: LncRNA NORAD could serve as a valuable biomarker to predict poor prognosis and LNM in various human tumors.


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