scholarly journals HASTE INTRAMEDULAR DE POLIPROPILENO, COMBINADA OU NÃO A BIOMATERIAIS, NO TRATAMENTO DE FRATURAS INDUZIDAS NO ÚMERO DE POMBOS

2004 ◽  
Vol 9 (1) ◽  
Author(s):  
C.R. TEIXEIRA ◽  
S.C. RAHAL ◽  
A.F.M. LIMA ◽  
M.A. CORREA ◽  
P. QUEIROZ ◽  
...  

O trabalho teve por objetivo avaliar a utilização da haste intramedular de polipropileno, combinada ou não a biomateriais de origem bovina, no tratamento de fraturas transversas induzidas no terço médio do úmero direito de pombos-domésticos. No grupo I (n=7), a fratura foi estabilizada por meio de haste intramedular de polipropileno aplicada em ambos os fragmentos da fratura, sem ultrapassar as articulações. No grupo II (n=7) utilizou-se a mesma fixação, porém foi aplicado junto ao foco de fratura uma mistura de biomateriais, constituída de proteínas morfogenéticas do osso e aglutinante de colágeno liofilizado. Em ambos os grupos, a asa foi imobilizada junto ao corpo com bandagem em forma de 8 por um período de 30 dias. Com seis semanas de pós-operatório, cinco fraturas do grupo I e quatro do grupo II estavam totalmente consolidadas. Foram observadas uma não consolidação hipertrófica (grupo I) e duas não consolidações com deslocamento do eixo ósseo (grupo II). Exceto as três aves que apresentaram complicações nas fraturas, as demais recuperaram a capacidade de vôo. Foi possível concluir que a haste intramedular de polipropileno foi um método de imobilização de eficácia limitada e os biomateriais utilizados não estimularam a consolidação das fraturas. Use of polypropylene intramedullary rod alone or combined with biomaterials for treatment of induced humeral transverse fractures in pigeons Abstract The aim of this study was to evaluate a polypropylene intramedullary rod alone or combined with biomaterials from bovine origin for the treatment of transverse fractures induced in the midshaft of right humerus in pigeons. In group I (n=7) the fracture was immobilized using a polypropylene intramedullary rod inserted into both fractured extremities without entering the joints. The same device was used in group II (n=7). Additionally, the fractured site in group II animals received a mixture of biomaterials composed by bone morphogenetic proteins and lyophilized collagen. In both groups a cast was applied to the affected wing, which was immobilized with a figure-of-8 bandage applied to the body and wing during 30 days. Complete healing was observed after six weeks of surgery in five and four animals from groups I and II, respectively. Observed complications included one hypertrophic nonunion (group I) and two nonunion with bone shaft dislocation (group II). Except for the three pigeons that showed postoperative complications, the remaining animals recovered the ability of flight. It was possible to conclude that the polypropylene intramedullary rod is a limited method of immobilization and the biomaterials used in this study did not stimulate fracture healing.

2022 ◽  
Author(s):  
Makaeva Ayna Maratovna ◽  
Sizova Elena Anatolevna ◽  
Atlanderova Ksenya Nikolaevna

Determining which forms of mineral feed additives can increase farm animal productivity is a key area of research. This study assessed the mineral composition of ruminal fluid and the effectiveness of calcium and phosphorus used by animals after the introduction of finely dispersed particles (FDP) of SiO2 (group I) and FeCo (group II) with a hydrodynamic radius of 109.6 ± 16.6 and 265 ± 25 nm, respectively. The deposition and use of calcium and phosphorus in the body of the experimental animals exceeded the control values. In group I, 30.8% more calcium was deposited (p ≥ 0.05), and in group II, the value was 30.3% (p ≥ 0.01). In the experimental groups, the calcium utilization rate was 27.3% higher in group I (p ≥ 0.05), and 28.2% higher in group II (p ≥ 0.01) compared to in the control. Phosphorus deposition was 34% higher (p ≤ 0.01) in experimental group I and 6% higher in experimental group II, compared with the control. Group I had a high utilization rate of phosphorus from the feed (with a 29% difference compared to the control). Comparison of the experimental groups revealed that the introduction of SiO2 FDP promoted an increase in the concentration of silicon, phosphorus, and calcium in the ruminal fluid. The introduction of FeCo FDP was accompanied by a decrease in the concentration of iron and cobalt in the ruminal fluid. Thus, the use of feed additive in finely dispersed form in the diet of animals was accompanied by an increase in the use of calcium and phosphorus by the animal’s body, which is advisable when intensifying milk and meat productivity. The obtained results require further research. Keywords: finely dispersed forms of microelements, ruminants, calcium and phosphorus exchange, feeding


Author(s):  
Laksmi Wulandari ◽  
Gatot Soegiarto ◽  
Anna Febriani ◽  
Farah Fatmawati ◽  
Wirya Sastra Amran

Abstract Introduction There are a substantial number of lung cancer patients with negative mutations in Indonesia. This type of cancer is deemed to be the major contributor of lung cancer patient’s death. However, reseaerch related to therapy using vinorelbine combined with platinum-based compounds is still scarce in Indonesia. The aim of this study was to compare the efficacy and tolerability between vinorelbine and carboplatin with vinorelbin and cisplatin in stage III-IV epidermal growth factor receptor (EGFR) mutations-negative non-small cell lung cancer (NSCLC). Methods The participants were divided into two groups—group I(vinorelbine–carboplatin) and group II (vinorelbine–cisplatin). The participants were assessed based on several measurement criteria. Not only Eq-5D was performed, but the body weight and response evaluation criteria for solid tumors (RECIST) were also examined. The participants received chemotherapy for four cycles (1 cycle = 21 days). Results The quality of life was considered stable in 60% of group I and 60% of group II (p=0.255). In both groups, 46.67% of participants had an increased body weight, while the other 20.00% was stable (p = 1.000). In terms of RECIST evaluation after the second cycle, 80.00% of group I and 86.67% of group II were considered to have a stable disease, with 20% of group I and none of group II had partial response (p = 0.027). However, after the fourth cycle, there were no significant difference between the groups (p = 0.734). Conclusion In EGFR mutation-negative NSCLC patients, the combination of vinorelbine and carboplatin showed comparable outcomes to vinorelbine and cisplatin chemotherapy with no significant differences.


2020 ◽  
Vol 6 (2) ◽  
pp. 73-76
Author(s):  
Anurag ◽  
Vishnu Gupta

Background: The thyroid gland is essential for normal growth of the body. This study assessed relation of external branch of superior laryngeal nerve to the superior pole of the thyroid gland. Subjects and Methods: This study was conducted on 25 human cadavers having 50 superior thyroid poles of both genders. Cadavers were classified based on age groups, group I was those with age less than 39 years and group II cadavers were those with age more than 40 years of age. Various measurements were performed on cadavers. Results: 14 cadavers were I group I and 11 were in group II. The mean mass was 67.2 Kgs in group I and 59.5 Kgs in group II, time elapsed after death was 481.5 minutes in group I and 476.4 minutes in group II, mean height was 1.74 meters in group I and 1.69 meters in group II, mean BMI found to be 22.3 kg/m2in group I and 20.1 kg/m2in group II. Height found to be significant between both groups (P< 0.05). The mean distance from EBSLN to cranial point of the thyroid gland was 6.66 mm in group I and 8.96 mm in group II. The mean transverse distance from superior thyroid artery to EBSLN was 3.55 mm in group I and 5.12 mm side in group II. The mean distance of the crossing point between the most cranial point of the thyroid lobe was 6.40 mm in group I and 11.47 mm in group II. The mean distance from the EBSLN to the midline of the neck was 19.80 mm in group I and 18.58 mm in group II. The mean distance from the EBSLN to the midline of the neck on the most cranial point of the cricoid cartilage was 18.77 mm in group I and 17.80 mm in group II. Conclusion: Authors found variation in measurements in left and right side in both group I and group II.


2021 ◽  
Vol 10 (22) ◽  
pp. 5299
Author(s):  
Łukasz Sikorski ◽  
Andrzej Czamara

The objective of this study was to assess the effectiveness of, and the correlation between, an average of 42 supervised physiotherapy (SVPh) visits for the vertical ground reaction forces component (vGRF) using ankle hops during two- and one-legged vertical hops (TLH and OLH, respectively), six months after the surgical suturing of the Achilles tendon using the open method (SSATOM) via Keesler’s technique. Hypothesis: Six months of supervised physiotherapy with a higher number of visits (SPHNVs) was positively correlated with higher vGRF values during TLH and OLH. Group I comprised male patients (n = 23) after SSATOM (SVPh x = 42 visits), and Group II comprised males (n = 23) without Achilles tendon injuries. In the study groups, vGRF was measured during TLH and OLH in the landing phase using two force plates. The vGRF was normalized to the body mass. The limb symmetry index (LSI) of vGRF values was calculated. The ranges of motion of the foot and circumferences of the ankle joint and shin were measured. Then, 10 m unassisted walking, the Thompson test, and pain were assessed. A parametric test for dependent and independent samples, ANOVA and Tukey’s test for between-group comparisons, and linear Pearson’s correlation coefficient calculations were performed. Group I revealed significantly lower vGRF values during TLH and OLH for the operated limb and LSI values compared with the right and left legs in Group II (p ≤ 0.001). A larger number of visits correlates with higher vGRF values for the operated limb during TLH (r = 0.503; p = 0.014) and OLH (r = 0.505; p = 0.014). An average of 42 SVPh visits in 6 months was insufficient to obtain similar values of relative vGRF and their LSI during TLH and OLH, but the hypothesis was confirmed that SPHNVs correlate with higher relative vGRF values during TLH and OLH in the landing phase.


AYUSHDHARA ◽  
2020 ◽  
Author(s):  
Anjli Sharma ◽  
Anjana Mishra ◽  
Manik Soni ◽  
Vijay Chaudhary

Medoroga is a condition in which there is an excessive accumulation of Meda Dhatu in the body. Accumulation of Medo Dhatu in different parts of the body causes blockage of Strotsa which ultimately leads to poor nourishment of other Dhathus. Lack of exercises and Kaphavardhak Ahar Viharar are the two main causes of Medoroga. In modern times, way of life has changed drastically to quick nourishments and inactive tendencies throughout the world. Because of these factors, accumulation of Meda dhatu happens immensely. In Ayurveda, dyslipidemia is considered under Medoroga. Dyslipidemia is an emerging serious health abnormality associated with co-morbidities including CVD that continues to be the leading cause of death worldwide. It is characterized by an increase in cholesterol, triglycerides, LDL levels, and a decrease in HDL levels. The present study has been designed to compare the efficacy of Triphala Kwath and Trikatu capsules on various clinical parameters in the management of Medoroga w.s.r to dyslipidemia. Twenty patients fulfilling the inclusion criteria were randomly selected for the trial and put into two groups of ten patients each. Trikatu capsules were given to patients in group I and Triphla kwath with Madhu and Trikatu capsules in combination were given to patients of group II for 8 weeks. Patients were thoroughly assessed on various scientific parameters during the complete trial period. In group II, a significant (p<0.001) improvement was observed in subjective parameters and serum cholesterol, triglycerides, LDL, VLDL levels while in group I, a significant (p<0.001) improvement was observed in HDL only. It may affirmatively be construed from the study that the best impact of the trial drugs was observed with Triphala Kwatha with Madhu and Trikatu Capsule together (i.e. Group II). This combination therapy was most effective in reducing the overall lipid profile with substantial gains related to subjective as well as objective parameters without any adverse effects.


2016 ◽  
Vol 144 (3-4) ◽  
pp. 174-180 ◽  
Author(s):  
Jelena Neskovic ◽  
Slavoljub Zivkovic ◽  
Milica Medojevic ◽  
Milos Maksimovic

Introduction. Endodontic retreatment is a complex intervention that requires detailed analysis of possible reasons for failure, and flawless practical execution of the procedure. Objective. The aim of the study was to assess the outcome of endodontic retreatment based on clinical and radiographic criteria after a two-year observation period. Methods. Clinical study included 49 teeth indicated for endodontic retreatment based on periapical index (PAI). All teeth were divided into two groups. Group I comprised teeth without any periapical lesion (PAI score of 1 and 2) while Group II consisted of teeth with visible periapical radiolucency (PAI score of 3, 4, and 5). Endodontic retreatment was completed in two visits with inter-appointment medication of 2% chlorhexidine and calcium hydroxide for two weeks. Outcome of endodontic retreatment was evaluated 12-24 months after final obturation. Results. Endodontic retreatment was successful in 93.3% in Group I after 24 months. In Group II, successful treatment and complete healing was found in 52.9% of teeth, whereas 14.7% of teeth showed only partial healing. However, clinical symptomatology was not present in any of the cases. Considering the absence of clinical signs and subjective symptoms, retreatment was successful in 67.6% of cases where chronic periapical inflammation was present. Conclusion. Endodontic retreatment was successful in high percentage in teeth with and without periapical lesions.


1969 ◽  
Vol 11 (4) ◽  
pp. 569-572
Author(s):  
M. A. Sharafeldin ◽  
I. A. Ramadan

SUMMARYAt birth, the Barki lambs used in this experiment were randomly allocated to three groups which numbered 133, 126 and 154 lambs of both sexes weaned at the ages of 10 weeks (Group I), 12 weeks (Group II) and 16 weeks (Group III) respectively.The most pronounced differences between the three groups of lambs in their body weights took place at the age from 4 to 6 months. Group II lambs performed as well as or even slightly better than the other two groups, which leads to the conclusion that as far as the body weight of lambs is concerned there is no need to extend their suckling period more than 12 weeks.The three groups of lambs varied little in their mortality rates from 2·5 to 12 months of age.


Author(s):  
H. Srinivasa Naik ◽  
Ch. Srilatha ◽  
K. Sujatha ◽  
B. Sreedevi ◽  
TNVKV Prasad

Background: Atherosclerosis is diverse disease with heterogenous mechanisms of progression and is an oxidative, chronic inflammatory and thrombotic disease produced by elevated level of low density lipoprotein cholesterol (LDL-C) in the blood. Initiation of atherosclerosis begins with the production of various inflammatory cytokines and adhesive molecules on the endothelium of the large muscular arteries like aorta. The present study was carried out to know the expression of TNF-Alpha and IL-18 by real time PCR (Polymerase chain reaction). Methods: Procured 24 Wistar albino rats and divided into two groups consisting of 12 rats in each. Atherosclerosis was induced by addition of 1% cholesterol and 15% saturated oil to the 1000g of standard rat diet and given to group II rats. Group I kept as control and maintained for 90 days. Result: Group II rats clinically showed obesity with significant increase (p less than 0.05) in the body weight. TC, TG, LDL-C, VLDL-C were significantly (p less than 0.05) higher, whereas HDL-C was significantly (p less than 0.05) reduced. Atherogenic diet induced the initiation of atherosclerosis in the aorta with degeneration of endothelial cells, sub intimal lipid laden macrophages (foam cells), slight thickening of the tunica intima with proliferation of few SMCs in group I rats. Present study revealed positive expression of TNF- alpha and no expression of IL-18 cytokine in the aorta of group II rats by RT-PCR.


2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Wang Guangjun ◽  
Tian Yuying ◽  
Jia Shuyong ◽  
Zhou Wenting ◽  
Zhang Weibo

Background. The specificity of acupuncture points (acupoints) is one of the key concepts in traditional acupuncture theory, but the question of whether there is adequate scientific evidence to prove or disprove specificity has been vigorously debated in recent years. Acupoint laterality is an important aspect of acupoint specificity. Data is particularly scarce regarding the laterality of the same channel, namesake acupoint located on opposite sides of the body. Our previous study results suggest that Neiguan acupoint (PC6) has the laterality. The aim of this study was to investigate whether Hegu (LI4) also has laterality from the perspective of heart rate variability.Methods. A total of twenty-eight healthy female volunteers were recruited for this study and were randomly separated into the group I (n=14) and the group II (n=14) according to the register order. In the group I, left LI4 was stimulated in the first epoch and the right LI4 was stimulated in the second epoch. In the group II, right LI4 was stimulated in the first epoch and left LI4 was stimulated in the second epoch. Electrocardiogram was recorded and heart rate variability was analyzed.Results. The results show that there were no significant differences of heart rate variablity between the group I and the group II in the time domain and in the frequency domain.Conclusions. Bilateral Hegu acupoints have the same effect on the heart rate variability of the healthy subjects.


2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Samuel Tung-Hsing Chiang ◽  
Shang-Min Yeh ◽  
Yi-Chen Chen ◽  
Shiun-Long Lin ◽  
Jung-Kai Tseng

The purpose of this study was to investigate the protective role of orally administered taurine against diabetic retinal changes via electroretinogram (ERG) and retinal histology on rabbits. Rabbits were randomly assigned into groups: Group I (vehicle administration only); Group II (diabetes: induced by 100 mg/kg alloxan injection); Group III (diabetes and fed with 200 mg/kg taurine); and Group IV (diabetes and fed with 400 mg/kg taurine). The body weight and blood glucose levels of the rabbits were monitored weekly. The ERG was measured on weeks 5 and 15. Retinal histology was analyzed in the end of the experiment. Results revealed that a taurine supplement significantly ameliorates the alloxan-induced hyperglycemia and protects the retina from electrophysiological changes. Group II showed a significant(P<0.05)change in the mean scotopic b-wave amplitude when compared to that of Group I, whereas the diabetic rabbits treated with taurine (Group III and IV) were analogous to Group I. Histologically, the amount of Bipolar and Müller cells showed no difference(P>0.05)between all groups and when compared with those of Group I. Our study provides solid evidences that taurine possesses an antidiabetic activity, reduced loss of body weight, and less electrophysiological changes of the diabetic retina.


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