scholarly journals Treatment outcomes and influencing factors on patients with Pulmonary Tuberculosis: a retrospective study

2021 ◽  
Vol 3 (2) ◽  
pp. 105-108
Author(s):  
Jamshid Ayatollahi ◽  
◽  
Abolhasan Halvani ◽  
Mohammadhesam Gharaei Khezri ◽  
Hossein Shahcheraghi ◽  
...  
Keyword(s):  
Side Effects ◽  
Frequency Distribution ◽  
Cross Sectional Study ◽  
The Body ◽  
Sputum Culture ◽  
Response To Treatment ◽  
Sputum Smear ◽  
Drug Side Effects ◽  
Cross Sectional ◽  
Significant Difference

Introduction: Tuberculosis infection caused by Mycobacterium tuberculosis is one of the most common infectious diseases, especially in countries such as Iran. The course of treatment and the number of drugs used vary depending on the severity of the disease and the parts of the body involved. The resistant tuberculosis to treatment has increased in recent years. Thus, this study was conducted to investigate the frequency distribution of response to treatment of patients with tuberculosis in Sirjan, Iran. Methods: This descriptive cross-sectional study investigated all patients with tuberculosis in Sirjan city who had referred to health centers during the years 2011-2019. The data collection tool was a pre-prepared checklist that included information on age, sex, sputum smear results, sputum culture results, diabetes, patients' nationality, drug side effects, and response to treatment. Finally, data was entered into SPSS version 22, and analyzed. Results: In this study, the overall response rate was 83% and the mortality rate was 10%. Between the frequency distribution of response to treatment in terms of gender, age, sputum smear results, sputum culture results, patients' nationality and diabetes was not statistically significant difference. Also, no statistically significant difference was found between the frequency distribution of pulmonary TB treatment response in terms of drug allergy, drug hepatitis and other drug side effects. Conclusion: According to results, can be concluded that none of the variables: age, sex, smear and culture result, and history of diabetes have no an effect on response to treatment and mortality of tuberculosis.

scholarly journals Evaluation of the Frequency Distribution of Oral Biopsies in Shahid Sadoughi Hospital in Yazd During 2010-2019

2021 ◽  
Vol 8 (3) ◽  
pp. 109-114
Author(s):  
Zahra Roustaeizade Shooroki ◽  
Sara Zare
Keyword(s):  
Frequency Distribution ◽  
Cross Sectional Study ◽  
The Body ◽  
Histopathological Diagnosis ◽  
Chi Square ◽  
Cross Sectional ◽  
Lower Lip ◽  
Significant Difference ◽  
The Mean ◽  
Gender Type

Background and aims: Oral mucosa is prone to various lesions. Some of these lesions can be early signs of a particular disease or even malignancy in the body. The aim of this study was to investigate the frequency distribution of oral biopsies from 2009 to 2019. Methods: In this analytical descriptive cross-sectional study, 621 records of the oral cavity biopsies performed in the pathology department of Shahid Sadoughi hospital were analyzed. Age, gender, type of lesion, site of lesion, histopathological diagnosis, year of referral, and medical specialist who performed the biopsy were included in the study checklist. The data were analyzed using chi-square and Kruskal-Wallis test in SPSS version 25.0. Results: Of 621 biopsies, 308 specimens belonged to men (49.6%) and 313 specimens belonged to women (50.4%). The mean age of patients was 46.58±21.08 years, ranging from 6 months to 95 years. The most affected areas were the tongue (33%), lower lip (29.1%) and cheeks (17.7%). squamous cell carcinoma (SCC) (27.9%), inflammatory lesions (26.1%), mucocele (14.8%), and ulcers (8.5%) were the most frequent lesions. There was a significant difference in the age of individuals with different lesions (P<0.001). Conclusion: The most frequent lesion diagnosed in biopsies was SCC. The most frequently affected sites were tongue and cheek. Lesions were more frequent in women and were most frequently seen in the fourth, fifth, and sixth decades of life.

Comparative assessment of odontometric parameters for gender determination: A hospital based cross-sectional study

2021 ◽  
Vol 8 (3) ◽  
pp. 147-152
Author(s):  
Mosmi Lomi ◽  
Jonathan Daniel M
Keyword(s):  
Sexual Dimorphism ◽  
Cross Sectional Study ◽  
Mean Value ◽  
The Body ◽  
Central Incisor ◽  
Maxillary Canine ◽  
Cross Sectional ◽  
Mean Values ◽  
Gender Determination ◽  
Significant Difference

Determining gender is one of the most important procedure in forensics. Teeth are made of the most enduring mineralized tissues in the body, as such, they have an extraordinary resistance to putrefaction and the effects of external agents (physical, thermal, mechanical, chemical or biological) which makes them invaluable material for anthropological, genetic, odontologic and forensic examinations.i)To assess the degree of sexual dimorphism in maxillary canine using maxillary canine index, maxillary first molar and central incisor using mesiodistal (MD) and buccolingual/buccopalatal (BL) dimensions of the crown. ii) To determine the accuracy of maxillary canine index, first molar and central incisor dimensions (mesiodistal and buccolingual/buccopalatal) in determining sex.This study consisted of total 30 participants (males=15, females=15) of age group ranging from 20 to 35 yrs. Measurement of dimensions of selected teeth were performed on maxillary cast using digital Vernier caliper, resolution 0.01mm. Data thus obtained were analyzed statistically.The mean values of all the measurements in males were greater than females. There was statistical significant difference in mean value of bucco-lingual width of molar, mesiodistal width of canine (on left side, right side and average) and the inter-canine distance between males and females. The buccolingual width of molar showed the highest % of sexual dimorphism (5.33%) and the mesiodistal width of molar showed the least % of dimorphism (0.7%). Bucco-lingual width of molar posed the highest prediction accuracy for gender determination. We conclude that buccolingual width of maxillary first molar can be used to predict the gender when only teeth of maxillary arch are available for forensic examination.

A Cross-Sectional Study to Compare Differences on Clinical and Laboratory Findings in Children with Seropositive and Seronegative Lupus

2021 ◽  
Author(s):  
Shima Salehi ◽  
Rozita Hosseini Shamsabadi ◽  
Hassan Otukesh ◽  
Reza Shiari ◽  
Monir Sharafi
Keyword(s):  
Autoimmune Disease ◽  
Disease Diagnosis ◽  
Cross Sectional Study ◽  
Rapid Identification ◽  
The Body ◽  
Musculoskeletal Symptoms ◽  
Laboratory Findings ◽  
Cross Sectional ◽  
Significant Difference ◽  
History Of

Abstract Background: Lupus is an inflammatory and autoimmune disease that involves various tissues and organs of the body. Identification of diagnostic elements to rapid identification of seronegative lupus cases is very important in order to prevent morbidity and progression of disease. This study aimed to compare clinical and laboratory findings of seropositive cases with seronegative lupus patients. Methods: This cross-sectional analytic study was performed on 43 children (17 seronegative and 26 seropositive) with lupus who were admitted to Ali Asghar Hospital during 2007-2017. Seropositive patients had anti-nuclear antibody (ANA) titration >1/80, while seronegative patients had ANA titration <1/80 (at the time of disease diagnosis). Clinical and laboratory findings were compared between two groups.Results: Serositis in patients with ANA- was significantly higher than ANA+ (41.17% vs. 23.07%; p = 0.042). ANA- group had higher autoimmune disease history than ANA+ group (42.85% vs. 15.0%; p = 0.041). The family history of the disease in the ANA- group was greater than ANA+ group (50% vs. 23.52%). The percentage of hypertensive patients in ANA- group was higher than ANA+ group (52.94% vs. 26.92%; p = 0.037). Neurologic symptoms in ANA+ and ANA- groups were 38.46% and 17.64%, respectively (p = 0.043). The frequency of patients with thrombocytopenia in ANA+ group was significantly greater than ANA- group (32% vs. 12.5%; p=0.041). There was no significant difference in other clinical and laboratory findings between two groups. Conclusion: Seronegative lupus patients had higher percentage of musculoskeletal symptoms, autoimmune disease history, familial history of disease, and hypertension, while neurological and thrombocytopenia symptoms were higher in seropositive patients compared to seronegative cases. Therefore, evaluation of these factors can be helpful to diagnosis of seronegative patients.

Serum Albumin Level as a Prognostic Marker for Covid-19 Positive Patients in Western Uttar Pradesh - A Cross Sectional Study

2021 ◽  
Vol 8 (04) ◽  
pp. 204-207
Author(s):  
Shreyansh Talera ◽  
Saurabh Singhal ◽  
Nishant Wadhera ◽  
Mayank Arora ◽  
Ravi Pratap
Keyword(s):  
Serum Albumin ◽  
Prognostic Marker ◽  
Serum Albumin Level ◽  
Uttar Pradesh ◽  
Cross Sectional Study ◽  
Albumin Level ◽  
The Body ◽  
Cross Sectional ◽  
Significant Difference

BACKGROUND WHO has declared Coronavirus disease 2019 (Covid-19) as a pandemic. Covid-19 leads to sickness and death. Human serum albumin (HSA) is the most common circulating protein in the body having oncotic as well as non-oncotic properties. The role of albumin in death among Covid-19 subjects, especially in this part of the country has not been frequently reported. The aim of the study was to analyse the role of serum albumin level as prognostic marker for Covid-19 positive patients. METHODS The present study was conducted in the department of Medicine at Chhatrapati Shivaji Subharti Hospital, Subharti Medical College, Meerut, UP. The study comprised of 100 subjects who were Covid positive from May 2020 to July 2020. A detailed explanation was given to all the participating respondents regarding the study and their contribution to it. Covid-19 was diagnosed on the basis of the WHO interim guidelines. A questionnaire was prepared to collect the patients’ demographic profile. Patients date of admission and discharge was recorded along with the outcome i.e., whether patient expired or survived. Patients’ diagnosis was identified along with the comorbidity (if present). Laboratory investigations comprised of CBC and serum albumin detection. Data so collected was tabulated in an excel sheet, under the guidance of statistician. Collected data was analysed using Statistical Package for the Social Sciences (SPSS) software version 24 and the tests used were t test and Fisher’s exact test and the level of significance was set at p < 0.05. RESULTS The study comprised of 100 subjects, out of which 45 were males and 55 were females. The overall mean age of the study subjects was 37.52 years. In our study, mortality was 35.29 %, 9.33 % and 85.7 % of the subjects having Covid-19+ type 2 diabetes (T2DM), only Covid-19 and Covid-19+ hypertension respectively with statistically significant difference as p < 0.05. Albumin level was significantly lower in expired patients (2.99) as compared to survivors (3.85) as p < 0.05. Hospital stay was also higher in expired patients. CONCLUSIONS Covid-19 patients had low serum albumin levels and that might play a role in the survival of patient. KEYWORDS Covid-19, Mortality, Albumin

scholarly journals A Cross-Sectional Study of Antibiotic Self-Medication

Thrita ◽  
2020 ◽  
Vol 9 (1) ◽  
Author(s):  
Fatemeh Mousavi ◽  
Parisa Shojaei ◽  
Azadeh Nazemi ◽  
Atefe Dadashi
Keyword(s):  
Logistic Regression ◽  
Side Effects ◽  
Cross Sectional Study ◽  
Study Data ◽  
P Value ◽  
Sectional Study ◽  
Self Medication ◽  
Chi Square ◽  
Cross Sectional ◽  
Significant Difference

Objectives: This research has been conducted to study antibiotic self-medication, prevalence, and reasons. Methods: A questionnaire containing 30 comprehensive questions in terms of the experience of antibiotic self-medication was prepared. In this cross-sectional study, data were analyzed using analytical statistics bases on chi-square and logistic regression. Results: The results showed that 61.3% of the participants were self-antibiotic users. There was a significant difference only between gender and self-medication such that self-medication in males was more than females (P value = 0.027). Conclusions: Self-medication of antibiotics is almost high and requires more information about the side effects of these drugs in order to promote rational and physically prescribed use.

scholarly journals A cross sectional study on clinical trends of reproductive performances and reproductive disorders of dairy cows in Rajshahi district of Bangladesh

2020 ◽  
Vol 6 (2) ◽  
pp. 340-350
Author(s):  
Rashida Khaton ◽  
Md Abul Hasnat ◽  
Md Royhan Gofur ◽  
Md Zakir Hossain ◽  
Md Alauddin ◽  
...  
Keyword(s):  
Dairy Cows ◽  
Reproductive Performance ◽  
Uterine Prolapse ◽  
Post Partum ◽  
Clinical Signs ◽  
Cross Sectional Study ◽  
Response To Treatment ◽  
Reproductive Disorders ◽  
Cross Sectional ◽  
Significant Difference

Performance evaluation of existing dairying is important to design relevant dairy development strategies and implement context specific interventions for future development of the dairy enterprise. The present study was carried out to evaluate the clinical trends (reproductive performance and disorders) of dairy cows of Rajshahi district, Bangladesh. A total of 500 cows randomly selected and data were collected directly from the dairy farms owners from 6 upazilas and 4 metro thanas of Rajshahi district by using questionnaires and diagnosis of reproductive disorders (RD) was made on the basis of history, clinical signs and response to treatment. The average reproductive performance (RP) were recorded as age at puberty 26.42±0.22 m, age at first calving 35.48±0.22 m, post-partum heat period 121.85±3.48 days, service per conception 1.93±0.04, days open 136.80±3.57 days and calving interval 401.04±3.94 days. The better RP was found at metro thanas compared to upazilas, though no significant difference was found except on service per conception (p<0.05). The overall prevalence of RD was 78.6% in Rajshahi district. Among the reproductive and productive disorders, anoestrus 24.6% was the highest prevalent disorders followed by abortion 13.4%, repeat breeding 11.4%, retained placenta 10.2%, dystocia 5.4%, mastitis 4.4%, vaginal prolapse 2.4%, pyometra 1.8%, metritis 1.6%, uterine prolapse 1.4%, milk fever 1.2% and still birth 0.8%. The highest occurrence of RD was recorded in Tanore upazila (92%) and the lowest in Poba upazila (62%). In comparison between the upazila and metro thanas the minimum occurrence of RD was recorded in metro thanas (31%) than upazilas (47.6%). Asian J. Med. Biol. Res. June 2020, 6(2): 340-350

scholarly journals Evaluation of Pupils’ Knowledge about Kidney Health

2021 ◽  
Vol 18 (23) ◽  
pp. 12811
Author(s):  
Theodore Vassilikopoulos ◽  
Athena Kalokairinou ◽  
Georgia Kourlaba ◽  
Eirini Grapsa
Keyword(s):  
Renal Function ◽  
General Education ◽  
Knowledge Score ◽  
Cross Sectional Study ◽  
The Body ◽  
Cross Sectional ◽  
Convenience Sample ◽  
Significant Difference ◽  
The Difference ◽  
Clinically Significant

The purpose of this study was to investigate the level of renal function knowledge of primary school pupils in Greece. We conducted a cross-sectional study with a convenience sample of 220 pupils, coming from the 5th and 6th grades of general education schools. A questionnaire consisting of 11 questions was developed from scratch. However, based on an analysis of Cronbach’s alpha values obtained when individual questions were deleted, two questions were removed from the analysis, and only nine remained for analysis and participated in the calculation of the knowledge score. Moreover, the gender and daily habits of pupils regarding water consumption and frequency of urination were recorded. Pupils had a high percentage of correct knowledge about the number of kidneys (95.2%), whether a child may have problems with the kidneys (85.5%) and whether a person can survive with one kidney (68.5%). Low levels of knowledge were observed in the function and role of the kidneys (36.4%), as well as the part of the body where the kidneys are located (30.9%). The median (interquartile range (IQR)) total knowledge score was 6 (5–7), with no difference detected between genders (p = 0.135). A statistically significant difference between pupils of 5th and 6th grades was found but the difference did not seem to be clinically significant (p = 0.035). The present research demonstrates that pupils’ knowledge of renal function and the protection of their kidneys needs improvement.

scholarly journals Assessment of Antibiotic Knowledge Among Final Year Pharmacy Students at Baghdad University

2019 ◽  
Vol 12 (1) ◽  
pp. 379-383
Author(s):  
Ehab Mudher Mikhael ◽  
Mohammed Khudhair Hasan ◽  
Sama Zaid Abdulridha
Keyword(s):  
Antibiotic Resistance ◽  
Side Effects ◽  
Cross Sectional Study ◽  
Legal Issues ◽  
Pharmacy Students ◽  
Public Health Issue ◽  
Cross Sectional ◽  
Validated Questionnaire ◽  
Life Saving ◽  
Significant Difference

Background: Antibiotics are life-saving drugs that if misused lead to antibiotic resistance and consequently to a substantial public health issue. Pharmacists have a major role in ensuring the rational use of antibiotics to prevent antibiotic resistance. This study aimed to assess antibiotic knowledge among final year pharmacy students at Baghdad University. Methods: A cross sectional study using a newly developed and validated questionnaire was given for 148 final year (5th stage) students at Baghdad University – College of Pharmacy during November 2016. Only 140 students (response rate 93%) completed the questionnaire. The 10 items-questionnaire consisted of 5 major domains: Antibiotic effectiveness, side effects, resistance, use in specific cases (e.g., during pregnancy and septicemia), and the legal issues of antibiotic dispensing. Results: Only 20% of students have good overall antibiotic knowledge. The least knowledge for pharmacy student was in regard to antibiotic side effects and antibiotic resistance at which only 22% and 19% of pharmacists possessed good antibiotic knowledge respectively. Knowledge of student was the best in legal issues of antibiotic dispensing. There was a non-significant difference in antibiotic knowledge between male and female pharmacy students. Conclusion: Antibiotic knowledge among pharmacy students at Baghdad University was very poor and less than expected.

scholarly journals Overuse of Steroid Drugs Methylprednisolone and Dexamethasone (Oral) Causes a Diabetic Patient to Become Infected with the Black Fungus in the Corona Virus.

2021 ◽  
Author(s):  
Ashwin Singh Chouhan ◽  
Bharat Parihar ◽  
Bharti Rathod ◽  
Ramprasad Prajapat
Keyword(s):  
Side Effects ◽  
Age Groups ◽  
Diabetes Patient ◽  
Cross Sectional Study ◽  
The Body ◽  
Cross Sectional ◽  
Ocular Infections ◽  
Excessive Consumption ◽  
Steroid Drugs ◽  
Potential Damage

Abstract Background Overuse of both methylprednisolone and dexamethasone drug on a corona patient can result in serious side effects and new infections may appear during their use. Prolonged use of methylprednisolone and dexamethasone may produce posterior subcapsular glaucoma, glaucoma with potential damage to the optic nerves, and may accelerate the establishment of secondary ocular infections caused by fungi or viruses.It has also been observed that more methylprednisolone and dexamethasone drug increases the level of glucose in the body, leading to normal corona patients who do not have any disease and diabetes after recovering from excessive consumption of methylprednisolone and dexamethasone drug.Materials and Methods A cross sectional study was conducted among 50 COVID doctors from the department's outpatient pool of COVID patients, distributing questionnaires to all subjects of different age groups. The questionnaire included information related to the name, age, gender and various factors that affect the doctor's choice of methylprednisolone and dexamethasone.Result and Discussion A total of 50 doctors and some medical stores from across India were included in the survey. Doctors prescribed more methylprednisolone and dexamethasone medicine than steroid medicines to corona patients. In our research, most side effects were observed for corona patients taking methylprednisolone and dexamethasone drug. Conclusion This research had shown that overdose of methylprednisolone and dexamethasone drug take diabetes patient he has serious eye effect and cause black fungus.

scholarly journals Perception of Side Effects of Chemotherapy among Cancer Patients in B.P. Koirala Memorial Cancer Hospital Bharatpur, Nepal

2016 ◽  
Vol 11 (4) ◽  
pp. 14-19 ◽  
Author(s):  
Sharmila Gurung ◽  
Radha Acharya Pandey
Keyword(s):  
Side Effects ◽  
Cancer Patients ◽  
Sampling Technique ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Significant Difference ◽  
Demand Information ◽  
And Gender ◽  
Loss Of Appetite ◽  
Patient’S Perception

jdjBackground & Objectives: These side effects of chemotherapy affect the patients’ daily life and quality of life adversely. It affects the different body system resulting in physical and non physical (psychosocial) side effects. Cancer patients demand information to understand chemotherapy-related adverse effects and actions to be taken. The aim of the study is to find out the perception of side effects of chemotherapy among cancer patients.Materials and methods: A descriptive cross-sectional study was conducted among 200 cancer patients, using purposive sampling technique and data was collected via face to face interview. Descriptive as well as inferential statistics (T-test) was used to see the significant difference between dependent and independent variables.Results: The overall perceived side effects of chemotherapy include: affects work and home duties (non physical side effect), followed by anxiety, loss of appetite, affects family, affect partner, feel constantly tired (fatigue), affects social activities, feel irritable, nausea and constipation respectively. There is significant difference between perception of side effects of chemotherapy and gender of respondents.Conclusion: The perceptions of side effects of chemotherapy are different from individual to individual. Patient’s perception of side effects of chemotherapy is concerned with non physical side effects rather than physical side effects.Journal of College of Medical Sciences-Nepal, Vol.11(4) 2015: 14-19

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