LONGER MASTICATION CYCLES TEND TO LOWER POST-PRANDIAL BLOOD SUGAR LEVELS

2021 ◽  
Vol 1 (Volume 1 No 1) ◽  
pp. 11-18
Author(s):  
Ike Rahmawaty Ali ◽  
Siska Nia Irasanti

Diabetes Mellitus (DM) is a metabolic syndrome occurred because of the lack of insulin hormone secretion or some factors disturbing insulin hormone or both of them. The mastication cycle is one of the factors related to the increasing in blood glucose. The research aims to analyse the relation between mastication cycle and DM risk factor on Faculty of Medicine students, Universitas Islam Bandung. The methodology was an experimental study. The subjects were 18 male Faculty of Medicine, Unisba, who fulfil the inclusive and exclusive criteria. First, scanning was conducted to know DM risk by questioners. Those students were divided into three groups of mastication cycle (15,30,45 cycle). Each group consisted of six students. The result showed that the tendency of average blood sugar was lower in the group with 45 cycles of mastication, compared to 30 and 15 cycles (86.5 vs 89.5 vs 92 mg/dL). However, according to a statistical calculation, there was no significant relationship between the mastication cycle and blood glucose (P =0.413; P>0.05). The average blood insulin level of 45 times the mastication cycle was the lowest compared to 30 and 15 mastication cycles (2.44 vs 2.97 vs 3.58 µg/ml). The result was that the mastication cycle was longer than the initial insulin release to work in the cell more effectively. In conclusion, DM needs to do more cycle in mastication food to maintain glucose in the blood.

2017 ◽  
Vol 4 (2) ◽  
pp. 24
Author(s):  
Fatifa Asmarani ◽  
Bambang Wirjatmadi ◽  
Merryana Adriani

Background: Diabetes mellitus (DM) is metabolic disorder syndrome characterized by hyperglycemia due to deficiency of insulin secretion. Patients of diabetic patients increases each year, so it needs proper handling. Corn flour is a source of carbohydrates with a low glycemic index to help reduce the rise in blood sugar levels. In addition, supplementation with tempeh flour containing isoflavones act to protect cells from free radical thereby inhibiting damage cells. Fiber in tempeh affect blood glucose levels because it slows the absorption of glucose.Objective: To determine the effect supplementation of corn flour with tempeh flour on blood sugar levels in diabetes mellitus Wistar rats.Methods: The study was true experimental design with Pre-posttest control group design, samples were 20 male Wistar rats aged 2-3 months were then divided into 4 groups (T0, T1, T2, T3.) T0 was injected with alloxan as 30 mg / 150 grams of BB rats are subsequently treated with standard diet; T1 was dministered by standard diet 50% + 50% corn flour; T2 was administered by standard diet 50% + 30% + corn flour tempeh flour 20%; and T3 was administered by standard diet of corn flour 50% + 15% + 35% tempeh flour for 2 weeks. Blood glucose levels were measured with a glucose kit (GOD FS). Research data were analyzed by One Way ANOVA followed by Tukey's Post Hoc test p-value <0.05.Results: There were significant differences on blood sugar levels in all groups (p = 0.000): control group (only dietary standards), T1 (administered by standard diet 50% + corn flour 50%), T2 (administered by a standard diet 50% + cornstarch 30% tempeh flour + 20%) and T3 (administered by standard diet of corn flour 50% + 15% + 35% tempeh flour).Conclusion: corn flour with tempeh flour supplementation effect on decresing of blood sugar levels.


Author(s):  
Nerdy Nerdy ◽  
Linta Meliala ◽  
Bunga Rimta Barus ◽  
Puji Lestari ◽  
Selamat Ginting ◽  
...  

Male infertility has occurred rapidly in the last few decades, primarily in developing countries. An antioxidant, hesperetin is a flavonoid that is found in abundance in orange peels. The aims of this research were to determine the effect of hesperetin on blood sugar levels, spermatozoaquality, and spermatozoa quantity. The research structure included induction of diabetes mellitus and treatment for 8 weeks, followed bydetermination of blood sugar levels, spermatozoa quality, and spermatozoa quantity. Hesperetin has the ability to restore blood sugar levels, spermatozoa quantity, seminiferous tubules diameter, and testicular weight, volume, and germinal epithelial layer thickness with significant difference from the normal control group. Hesperetin did not fully restore spermatozoa motility, viability, and morphology with significant difference from the normal control group, nor from the positive control group. However, overall, hesperetin decreased blood glucose levels, increased spermatozoa quantity, and improved the spermatozoa quality in alloxan-induced diabetes mellitus mice. Dose-dependent activity was observed with the optimum dose at 200 mg/kg body weight.


2017 ◽  
Vol 2 (1) ◽  
pp. 5
Author(s):  
Ludiana Ludiana

Diabetes mellitus is a chronic metabolic disorder marked increase in blood glucose. According to the World Health Organization (WHO) in 2013 the incidence of diabetes mellitus in the world reached 347 million people in Indonesia alone ranks among the seven countries with the highest diabetes prevalence of 7.6 million people. Among the causes of the increase in blood glucose levels in diabetics is due to psychological factors, namely anxiety. In the pre-survey results in Puskesmas Sumbersari Bantul note that from 8 patients with diabetes mellitus, there are 6 people experiencing anxiety and 2 do not complain any signs of anxiety. The purpose of this study was to determine the relationship of anxiety with blood glucose levels of diabetics mellitus in Puskesmas Sumbersari Bantul District of South Metro City. The type quantitative research, form design used is cross sectional. The population in this study are patients with diabetes mellitus in Puskesmas Sumbersari Bantul District of South Metro totaling 408 samples taken as many as 41 people. The analysis in this study using the test Person Product Moment. Statistical analysis showed that anxiety patients with diabetes mellitus are at an average score of 27.44 with a standard deviation of 4.353 and the average blood sugar levels of people with diabetes mellitus are at 339.78 mg / dL with a standard deviation of 74.742. In the Person Product Moment test results proved no relationship anxiety with blood sugar levels of people with diabetes mellitus (p-value = 0.000 <a 0.05). Pearson correlation results obtained value of 0.817 towards a positive correlation with the strength of the relationship is very strong. Conclusions research shows there is an anxiety relationship with blood glucose levels of diabetics mellitus.


2019 ◽  
Vol 2 (4) ◽  
Author(s):  
Agung B S Satyarsa

Diabetes mellitus is a degenerative disease that commonly found and related to an unhealthy lifestyle and genetic factors. Current management of diabetes mellitus includes control of blood sugar levels and prevention of complications. Recent studies found that many phytochemicals have the potential to control blood sugar levels in patients with diabetes. Alkaloid substances from leaves of Tapak Dara have an effect on decreasing blood glucose. This review article aims to describe the potential effects of the Alkaloid vindolicine from Tapak Dara leaves (Catharanthus Roseus L.) in reducing blood glucose levels in patients with type 2 diabetes mellitus. The activity of vindolicine alkaloid against ? cells in previous studies has shown to improve ? cells activity and induce insulin secretion thus preventing further hyperglycemia. In addition, the vindolicine alkaloid also has a role in activating pancreatic ?-TC6 cells and carrying out an immediate reaction in blood vessels. As conclusion, further research is needed to prove the maximum effect of the utilization of tread leaf extract as well as the toxicity test to determine the toxic effects of the alkaloid substances in the tread leaf. Keywords: Type 2 Diabetes Mellitus, Vindolicine Alkaloid, Tapak Dara, blood glucoselevels


2021 ◽  
Vol 10 (1) ◽  
pp. 20
Author(s):  
Konita Shafira ◽  
Abu Bakar ◽  
Erna Dwi Wahyuni

Introduction : Diabetes Mellitus (DM) is a group of metabolic diseases characterized by hyperglycemia caused by abnormalities in insulin secretion, thus impacting on blood glucose levels. Calabura muntingia leaves are traditionally used as an alternative medicine because they contain flavonoid compounds which have anti-diabetic properties. In general, it is known that how to make traditional medicine is by boiling it, where the solvent only uses water so that the polar compounds will be attracted. The purpose of this study is to explain effectiveness the effect of administration between calabura muntingia leaves and calabura muntingia fruit through a review of studies related to blood sugar levelsin the last ten years.Method : Search for journals or articles using Scopus, Proquest, and Scholar indexed databases using appropriate keywords. The Center for Review and Dissemination and The Joanna Briggs Institute was used to assess the quality of the study. The framework used for the review is PICOS and the inclusion criteria used are English and Indonesian journals published in 2010 to 2020. Data analysis and tabulation are carried out in articles or journals. Title, abstract, full text and methodology are assessed to determine the eligibility of the article or journal.Results : Six hundred and forty-one articles were identified, there were eleven articles that fit the research criteria. The leaves of muntingia calabura and fruit of muntingia calabura contain flavonoids and saponins which can reduce blood sugar levels. A flavonoid compound that is thought to have activity in reducing blood glucose levels is quercetin.Conclusion : The form of extract, infusion, juice and stew did not change the content of the calabura muntingia plant.


Author(s):  
S. Yadav ◽  
S. Singh ◽  
M. K. Sharma ◽  
J. N. Puri ◽  
N. A. Ansari ◽  
...  

Insulin, Glibenclamide and Tolbutamide are some of the frequently used drugs for the most common metabolic disorders, diabetes mellitus. Along with hypoglycaemic drugs diabetic patient is exposed to variety of drugs. NSAIDs are one of the commonly used drugs in this metabolic syndrome. When a patient on hypoglycaemic drugs receives NSAIDs there are chances of drug interactions. This study was undertaken in the department of Pharmacology, GSVM medical college, Kanpur (UP) after approval by the institutional animal ethics committee to find out the interaction if any between Diclofenac and three hypoglycaemic drugs i.e. insulin, glibenclamide and tolbutamide.<p>Young healthy rabbits were divided into six groups: five rabbits in each group. First group received Insulin 1 u/kg subcutaneously; second Glibenclamide 0.05 mg/kg orally; third Tolbutamide 40 mg/kg orally; fourth Diclofenac 1mg/kg orally and insulin 1mg/kg s.c. simultaneously; fifth glibenclamide 0.05mg/kg orally at 0 hour and diclofenac 1mg/kg orally at 2 hours and sixth tolbutamide 40mg/kg orally at 0 hour and diclofenac 1mg/kg orally at 2 hours. Blood samples were taken at 0, 1, 2, 4 and 6 hours for blood sugar estimation. Mean blood sugar levels reduced significantly from their fasting levels when insulin, glibenclamide and tolbutamide were administered. However blood sugar levels did not showed any significant changes when diclofenac was administered along with insulin, glibenclamide and tolbutamide in comparison to when insulin, glibenclamide and tolbutamide were given alone. The results showed that diclofenac does not interact with insulin, glibenclamide and tolbutamide on blood sugar levels in rabbits.No Abstract.</p>


2018 ◽  
Vol 25 (1) ◽  
pp. 33
Author(s):  
Nurhayati Muslimin ◽  
Lydia Fanny ◽  
Manjilala Manjilala

Diabetes Mellitus (DM) is a collection of symptoms that arise in someone who has increased blood sugar levels (Glucose) due to lack of insulin hormone. The content in purple and tempe sweet potatoes has high amylose fiber content, and low IG improves insulin sensitivity, decreases glucose uptake rate, and is useful in controlling blood glucose so as to reduce the risk of complications in people with diabetes mellitus type 2 .This study aims to determine the effect of pastry cake flour sweet potato purple and tempe powder to blood sugar levels in patients with diabetes mellitus Type 2 in dr. Tajuddin Chalid Makassar.This study is an analytical study with Pre-Experiments by looking at blood glucose levels in the subjects who suffer from diabetes mellitus type 2 with the number of samples senbanyak 12 respondents. The result of data analysis of the effect of sweet potato pie cake and tempe powder to Diabetes Mellitus Type 2 patients was analyzed using SPSS with Wilcoxon test. The presentation of data is presented in tabular and narrative form.The results show Asymp.Sig (2-tailed) is 0.005. Because Asymp.Sig (2-tailed) is worth 0.005 which means There is effect of cake pastry sweet potato purple powder and tempe powder to blood sugar while in patient of Diabetes Mellitus Type 2 in dr. Tadjuddin Chalid Makassar.It is advisable to control blood sugar regularly at least once a month, physical exercise such as doing regular physical activity at least 3 times a week, and multiply the activities at home. Should counseling about Diabetes Mellitus type 2 Related to the recommended foodstuffs and is not recommended for people with Diabetes Mellitus (DM) type 2.


Author(s):  
Anung Putri Illahika ◽  
Hean Safira

Abstract  Diabetes Mellitus is a worldwide metabolic disease and becomes a challenge for the health practitioner. Unfortunately, less than half of these diabetic individuals are aware of their conditions, and less than 1% of those receiving medical treatment achieve their therapeutic targets. Acupressure is an alternative method that is believed to be an effective way of treating diabetic patients with reducing symptoms and complications. This research aims to discover the effect of period acupressure therapy on blood sugar levels in type two diabetes mellitus patients in Lumajang Acupressure Clinic. It uses an observational analytic design with pre-test and post-test approach. It involved 36 participants who were split into two groups and contained 18 participants for each group. The first group received acupressure therapy for three weeks, while the second group received eight weeks. Both groups underwent acupressure at the San Yin Jiao (SP-6) acupoint for 20 minutes three times a week. All participants in both groups had their blood glucose checked before and after acupressure therapy. The results showed that the two groups were significantly different for the paired t-test and the independent t-test. The acupressure therapy period has an effect on decreasing blood sugar levels in type two diabetes mellitus patients at Lumajang acupressure clinic. Keywords             : Acupressure, the period of therapy, blood glucose level, type two diabetes mellitusCorrespondence   : [email protected]


2020 ◽  
Vol 4 (1) ◽  
pp. 417
Author(s):  
Lismayana Hansur ◽  
Dara Ugi ◽  
Ami Febriza

ABSTRAKDiabetes mellitus merupakan salah  satu penyakit tidak menular yang memiliki prevalensi yang semakin  meningkat di negara berkembang.  Rendahnya  pengetahuan  masyarakat  menjadi salah satu penyebab peningkatan tersebut, terutama didaerah pedesaan dan daerah pinggiran kota. Saat ini upaya penanggulangan penyakit diabetes mellitus belum menempati skala prioritas utama dalam pelayanan kesehatan, walaupun diketahui dampak negatif yang ditimbulkannnya cukup besar antara lain komplikasi kronik pada penyakit jantung , hipertensi,  sistem saraf, hati, mata, dan ginjal. Mengingat insidensi diabetes mellitus yang terus meningkat dan bahaya komplikasi yang ditimbulkan, maka perlu dilakukan penyuluhan pencegahan dan penanganan penyakit diabetes mellitus termasuk pemeriksaan kadar gula darah agar warga di kelurahan tamarunang kecamatan somba opu kabupaten gowa melakukan pencegahan sejak dini. Metode pengabdian yang telah dilaksanakan meliputi Penyuluhan pencegahan  dan terapi diabetes mellitus melalui metode presentasi dan pemeriksaan kadar gula darah menggunakan kit.Hasil kegiatan penyuluhan dan pemeriksaan darah inidapat member informasi dan pengetahuan mengenai pencegahan dan penanganan penyakit diabetes melalui pengaturan pola makan.  Selain itu Bagi masyarakat yang belum pernah melakukan pemeriksaan  kesehatan sebelumnya, pemeriksaan kesehatan tersebut dapat berfungsi  sebagai skrining kesehatan untuk mengetahui status kesehatannya saat ini  sehingga dapat diambil tindakan  lebih lanjut. Kegiatan penyuluhan berlangsung dengan lancar dan masyarakat mendengarkan dengan antusias, Dari 27 orang yang diperiksa kadar gula darahnya ditemukan 4 orang dengan kadar gula darah melebihi batas normal (< 200 mg/dl). Kata kunci: diabetes mellitus; kadar gula darah; penyuluhan; komplikasi kronik. ABSTRACTDiabetes mellitus, which is one of the non-communicable diseases, has an increasing prevalence in developing countries. Low community knowledge is a factor of this increase, especially in rural and suburban areas. Currently, diabetes mellitus prevention efforts have not been put as the priority in health services. However, it has been understood that the negative impacts are rather severe (e.g., chronic complications in heart disease, hypertension, nervous system, liver, eyes, and kidney). Given the incidence of diabetes mellitus and the danger of its complications, which are increasing, its prevention, including blood glucose examination, need to be socialized so that residents in sub-district Tamarunang, Somba Opu, Gowa can do it early. Some services which have been implemented include socialization of the diabetes mellitus prevention and therapy, through presentation and Test blood glucose with a blood glucose meter. This counseling and blood examination results can provide information and knowledge on how to prevent and manage diabetes through dietary regulation. Besides, this health examination may serve as a health screening for people who have never had a previous medical test to determine their current health status to take further action. The counseling activities went smoothly, and the community listened enthusiastically. Four out of the 27 people who checked their blood sugar levels exceeded normal limits (<200 mg/dl). Keywords: diabetes mellitus; blood sugar level; counseling; chronic complication.


2018 ◽  
Vol 9 (3) ◽  
pp. 451
Author(s):  
Hotma Rumahorbo ◽  
Nani Avianti ◽  
Desmaniarti Zaini

The prevalence of Diabetes Mellitus (DM) in Indonesia shows an increase from 1.1% in 2007 to 2.1% in 2013, with the most cases being Type 2 Diabetes Mellitus. DM is a chronic disease that cannot be cured but can be controlled by healthy lifestyle and medicine. DM patients who cannot control their blood sugar levels, they will experience acute and chronic complications such as diabetic retinopathy, diabetic nephropathy, and diabetic neuropathy, causing the patient to undergo hospital treatment for the management of blood sugar levels and complaints arising from the accompanying illness. This situation makes the patient stress and depression which will aggravate the disease. This study was to measure the effectiveness of progressive relaxation interventions on depressive symptoms of DMT-2 patients. The study design used Quasi-Experimental two groups pre and post-test design, with 61 samples consisting of 31 intervention groups and 30 control groups. The intervention group was given guidance and progressive relaxation exercises 2 times a day for 3 consecutive days with a duration of 30 minutes each exercise. The results showed that progressive relaxation interventions in DMT-2 patients reduced depression scores by -11,368 units significantly (p=0.001). Variable that makes it difficult to reduce depression symptoms were blood glucose levels. Blood glucose levels were increasing depression scores by 0.012 units. The conclusion was a progressive relaxation intervention effectively reduce depression scores of DMT-2 patients. Controlling the patient's blood glucose levels is important in improving the effectiveness of progressive relaxation interventions to reduce depressive symptoms of DMT-2 patients.


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