scholarly journals Overview of Serum Uric Acid Levels in Adolescents with Overweight and Obesity

2019 ◽  
Vol 1 (4) ◽  
pp. 63-67
Author(s):  
Thothilath Sampan

Nowadays, obesity has become a serious problem world-wide. Obesity can cause the emergence of various kinds of diseases; one of them is hyperuricemia. This condition could found in obese adult as well as in obese adolescence. This study was aimed to obtain the serum uric acid level profile among high school students with overweight and obesity. This was a descriptive study with a cross sectional design. Subjects were students of Gen Panteleon High School with body mass index (BMI) >85. There were 23 students involved in this study. The results showed that 60.87% subjects had hyperuricemia. Most adolescence with obesity tend to have uric acid level above normal value.

2018 ◽  
Vol 6 (1) ◽  
Author(s):  
Inggrianno G.V Matialu ◽  
Murniati Tiho ◽  
Youla A. Assa

Abstract: Nowadays, obesity has become a serious problem world-wide. Obesity can cause the emergence of various kinds of diseases; one of them is hyperuricemia. This condition could found in obese adult as well as in obese adolescence. This study was aimed to obtain the serum uric acid level profile among high school students with overweight and obesity. This was a descriptive study with a cross sectional design. Subjects were grade X-XI students of SMA Negeri 2 Bitung with body mass index (BMI) >85. There were 23 students involved in this study. The results showed that 60.87% subjects had hyperuricemia. Conclusion: Most adolescence with obesity tend to have uric acid level above normal value.Keywords: adolescence, obesity, hyperuricemia, serum uric acidAbstrak: Obesitas saat ini sudah menjadi sebuah permasalahan serius bagi dunia. Obesitas dapat menyebabkan timbulnya berbagai penyakit seperti hiperurisemia. Masalah hiperurisemia tidak hanya terjadi pada orang dewasa yang obes tetapi juga dapat menyerang remaja yang obes. Penelitian ini bertujuan mengetahui gambaran kadar asam urat serum pada siswa yang mengalami overweight maupun obesitas. Jenis penelitian ini ialah deskriptif dengan desain potong lintang. Subjek penelitian ialah siswa kelas X-XI SMA Negeri 2 Bitung yang memiliki IMT diatas persentil 85 sebanyak 23 siswa. Hasil penelitian menunjukkan bahwa sebanyak 60,87% siswa mengalami hiperurisemia. Simpulan: Remaja dengan obesitas cenderung memiliki kadar asam urat di atas normal.Kata kunci: remaja, obesitas, hiperurisemia, asam urat serum


2020 ◽  
Vol 3 (2) ◽  
pp. 42-46
Author(s):  
Eko Lianto Rihardi ◽  
Adhlan Nury M. A. S. A. ◽  
Ananda Rivaldo Sari

Nowadays, obesity has become a serious problem worldwide. Obesity can cause the emergence of various kinds of diseases; one of them is hyperuricemia. This condition could found in obese adults as well as in obese adolescence. This study was aimed to obtain the serum uric acid level profile among high school students with overweight and obesity. This was a descriptive study with a cross-sectional design. Subjects were students of Gen Panteleon High School with body mass index (BMI) >85. There were 23 students involved in this study. The results showed that 60.87% of subjects had hyperuricemia. Most adolescence with obesity tend to have a uric acid levels above the normal value.


2017 ◽  
Vol 5 (2) ◽  
Author(s):  
Paterick R. Rampi ◽  
Youla A. Assa ◽  
Yanti M. Mewo

Abstract: Diseases caused by high uric acid levels are still commonly found in societies world wide. There is a correlation between uric acid level and increased body mass index (BMI). Higher body mass index in this case overweight and obesity is associated with higher risk of insulin resistance and excessive leptin production which may contribute to hyperuricemia. This study was aimed to obtain the profile of serum uric acid level among students with a BMI of ≥23 kg/m2 at Faculty of Medicine, Sam Ratulangi University. This was a descriptive study with a cross sectional design. Samples were obtained by using total sampling method. There were 53 respondents that met the inclusion and exclusion criteria. The results showed that there were 48 respondents (90.6%) whose serum uric acid levels were within normal limits, one respondent (1.9%) with hyperuricemia, and four respondents (7.5%) with hypouricemia. Conclusion: The majority of respondents had uric acid level within normal limit.Keywords: serum uric acid, body mass index, students Abstrak: Penyakit yang disebabkan akibat tingginya kadar asam urat masih banyak diderita oleh masyarakat dunia sekarang ini. Terdapat hubungan antara kadar asam urat dengan peningkatan indeks massa tubuh (IMT). Semakin tinggi indeks massa tubuh dalam hal ini overweight dan obesitas berhubungan dengan semakin tinggi juga risiko terjadinya resistensi insulin dan produksi leptin yang berlebih sehingga keadaan ini dapat berkontribusi menimbulkan hiperurisemia. Tujuan penelitian ini untuk mengetahui gambaran kadar asam urat serum pada mahasiswa dengan IMT ≥23 kg/m2 di Fakultas Kedokteran Universitas Sam Ratulangi. Jenis penelitian ialah deskriptif dengan desain potong lintang. Pengambilan sampel dengan menggunakan teknik total sampling. Terdapat 53 responden yang memenuhi kriteria inklusi dan eksklusi. Hasil penelitian memperlihatkan 48 responden (90,6%) memiliki kadar asam urat serum dalam batas normal, satu responden (1,9%) dengan hiperurisemia, dan empat responden (7,5%) dengan hipourisemia. Simpulan: Sebagian besar responden memiliki kadar asam urat serum dalam batas normal.Kata kunci: asam urat serum, indeks massa tubuh, mahasiswa


2020 ◽  
Vol 7 (7) ◽  
pp. 1136
Author(s):  
SK. Kabir Ahammed ◽  
A. B. M. Kamrul Hasan ◽  
Mohammed Ruhul Kabir ◽  
Gunosindhu Paul ◽  
Shishir Kumar Basak ◽  
...  

Background: The association of hyperuricemia with various cardiovascular risk factors has often led to the debate of whether hyperuricemia is an independent risk factor for essential hypertension (HTN).  The current study was conducted to see the relationship between serum uric acid and essential HTN in Bangladeshi adults.Methods: In this cross-sectional study, conducted in a tertiary hospital of Bangladesh, 155 patients with essential hypertension (newly detected or on treatment) aged ≥18 years and 100 age-sex matched normotensive subjects were investigated. Serum uric acid, plasma glucose, serum creatinine, and lipid profile were measured in all in fasting samples.Results: The frequency of hyperuricemia was higher in the hypertensive group in comparison to the normotensive control group (29.7% vs. 6.0%, p<0.001). Serum uric acid level was higher in the hypertensive subjects than the controls (6.10±0.88 vs. 5.38±0.54 mg/dL, mean±SD, p<0.001). In the hypertensive group, subjects with stage II HTN had higher serum uric acid than those with stage I HTN (6.46±0.83 vs. 5.72±0.78 mg/dL, mean±SD, p<0.001). In the hypertensive group, uric acid level showed significant positive correlations with both systolic and diastolic blood pressure though in the control group uric acid showed such correlation with systolic BP only.Conclusion: Patients with essential hypertension had higher serum uric acid compared to normotensive controls; uric acid level showed positive correlations with systolic and diastolic BP in the hypertensive subjects.


2020 ◽  
Vol 32 (2) ◽  
pp. 67-72
Author(s):  
Khairun Nahar ◽  
Sayada Fatema Khatun ◽  
Naila Atik Khan

Background: Serum uric acid is a relatively insoluble metabolite of purine metalolism which is mainly secreted by the kidneys and the rate is dependant on renal blood flow . It increases in preeclampsia and studies show it may be marker of severe preeclampsia. Methods and materials: This cross sectional study was conducted in Dhaka Medical College Hospital in eclampsia ward of gynae & Obs department during the period from January 2010 to December 2011 with the objective to determine the serum uric acid level in preeclampsia, to compare the serum uric acid level between mild and sever preeclampsia and to find out any relationship of the serum uric acid level with hypertension in preeclampsia. The study group composed of 92 diagnosed case of preeclampsia patient. Out of the 92 cases, 42 had mild preeclampsia (group-A) and 50 had severe preeclampsia (group B). Result: The results of the study showed that the mean serum uric acid level was significantly higher in severe preeclampsia (6.91+1.02) compared to mild preeclampsia (4.99 + 0.80) and there is a positive and significant relationship of serum uric acid level with severity of hypertension in preeclampsia (p<.0001). Conclusion: There is significant association between serum uric acid level and severity of hypertension in Preeclampsia. Bangladesh J Obstet Gynaecol, 2017; Vol. 32(2) : 67-72


Author(s):  
Desmawati Desmawati ◽  
Yuniar Lestari ◽  
Ulya Uti Fasrini ◽  
Delmi Sulastri

Background: Hyperuricemia is a predictor of metabolic syndrome influenced by many factors, one of which is nutritional status. A highly prevalence overweight and obesity in ethnic Minangkabau is quite high which can increase the prevalence of hyperuricemia. This study aims to determine the relationship of nutritional status intake with Minangkabau ethnic male uric acid levels.Methods: This study used a cross-sectional design, done in August to November 2016. Nutritional status was obtained through the measurement of body mass index (BMI) based on height and weight. The uric acid level examined in the Prodia laboratory. Data were analyzed by using chi-square test.Results: Most of subject were obesities. A total of 21% subjects suffers hyperuricemia. Statistic test results showed that there was a significant relationship between nutritional status and serum uric acid levels (p <0.0001).Conclusions: There was a significant relationship between nutritional status and serum uric acid levels in Minangkabau ethnic men in Padang city.


Healthcare ◽  
2021 ◽  
Vol 9 (12) ◽  
pp. 1681
Author(s):  
Soyeon Kang ◽  
Dongjin Kwon ◽  
Jiwoo Lee ◽  
Youn-Jee Chung ◽  
Mee-Ran Kim ◽  
...  

Background: Uric acid is one of natural antioxidants in human body. There have been several studies on the correlation between uric acid with oxidative stress and osteoporosis. However, the data are insufficient and results are controversial. In this regard, we determined the association between uric acid levels and bone mineral density (BMD) during the postmenopausal period. Methods: We analyzed data from 328 postmenopausal women (mean age, 57.3 ± 6.5 years; mean serum uric acid level, 4.6 ± 1.0 mg/dL). The participants were divided into three groups based on tertiles of the serum uric acid level. The participants receiving hormone replacement therapy (HRT), bisphosphonates, or lipid-lowering agents were included. Results: Blood urea nitrogen, serum creatinine, and serum triglyceride levels were significantly higher in the upper tertiles of uric acid levels. No significant difference was found in the mean uric acid levels between medication users and non-users. Each HRT regimen had a different mean serum uric acid level. A cross-sectional analysis showed no significant correlation between the serum uric acid levels and BMD in the spine and femoral neck (spine BMD: 1.050 ± 0.131, 1.060 ± 0.160, 1.084 ± 0.140, p = 0.22; femoral neck BMD: 0.837 ± 0.110, 0.849 ± 0.096, 0.863 ± 0.115, p = 0.28 for each tertile of uric acid). Longitudinal analysis of data from 186 women with follow-up examinations at a mean interval of 14.6 months also revealed no difference in reduction in both spine and femoral neck BMD between tertile groups of serum uric acid (the median BMD reduction for spine: −0.02, 0.01, −0.04, p = 0.95; the median BMD reduction for femoral neck: 0.008, 0.005, −0.003, p = 0.34). Conclusions: Serum uric acid level is not associated with BMD in postmenopausal women.


BMJ Open ◽  
2019 ◽  
Vol 9 (5) ◽  
pp. e028007 ◽  
Author(s):  
Wei-dong Lin ◽  
Hai Deng ◽  
Pi Guo ◽  
Fang-zhou Liu ◽  
Ru-yin Chen ◽  
...  

ObjectivesThere are country and regional variations in the prevalence of hyperuricaemia (HUA). The prevalence of HUA and non-valvular atrial fibrillation (NVAF) in southern China is unknown.DesignA cross-sectional study.Setting and participantsA total of 11 488 permanent residents aged 35 or older from urban and rural areas of Guangzhou, China were enrolled. A questionnaire was used to compile each participant’s demographic information and relevant epidemiological factors for HUA and NVAF. All participants were assessed using a panel of blood tests and single-lead 24-hour ECG.Main outcome measuresHUA was defined as serum uric acid level >420 μmol/L in men and >360 μmol/L in women. NVAF was diagnosed as per guidelines.ResultsThe prevalence of HUA was 39.6% (44.8% in men and 36.7% in women), and 144 residents (1.25%) had NVAF. Prevalence of HUA increased with age in women but remained stably high in men. After adjusting for potential confounders, age, living in urban areas, alcohol consumption, central obesity, elevated fasting plasma glucose level, elevated blood pressure, lower high-density lipoprotein cholesterol level and elevated triglycerides level were associated with increased risk of HUA. Residents with HUA were at higher risk for NVAF. Serum uric acid level had a modest predictive value for NVAF in women but not men.ConclusionsHUA was highly prevalent among citizens of southern China and was a predictor of NVAF among women.


Sign in / Sign up

Export Citation Format

Share Document