Endometrial cancer and physical activity

2018 ◽  
Vol 8 (1) ◽  
pp. 202-206
Author(s):  
R. Terlikowski ◽  
Z. Łada ◽  
MA. Strzyż-Skalij ◽  
K. Kryński ◽  
M. Osmólska ◽  
...  
Keyword(s):  
Physical Activity ◽  
Endometrial Cancer ◽  
Risk Factor ◽  
Epidemiological Studies ◽  
Objective Measures ◽  
Practical Reasons ◽  
Metabolic Equivalent ◽  
Metabolic Equivalent Of Task ◽  
The Relationship ◽  
Reduced Risk

Physical activity (PA) is an important modifiable risk factor for endometrial cancer (EC). PA has been studied using diverse measures including metabolic equivalent of task MET, duration, frequency and subjective levels, but for practical reasons most of epidemiological studies use questionnaires rather than objective measures to document PA. Moderate-intense daily PA has a protective effect and have a 20-40% reduced risk of EC. In this rewiev complex and variable behaviour, and the ability of epidemiological studies to determine the relationship between PA and EC has been discussed.

scholarly journals Cannabis use, sedentary behavior, and physical activity in a nationally representative sample of US adults

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Lydia Q. Ong ◽  
John Bellettiere ◽  
Citlali Alvarado ◽  
Paul Chavez ◽  
Vincent Berardi
Keyword(s):  
Physical Activity ◽  
Sedentary Behavior ◽  
Vigorous Physical Activity ◽  
Health Impact ◽  
Cannabis Use ◽  
Objective Measures ◽  
Health And Nutrition ◽  
Nationally Representative ◽  
The Relationship ◽  
Potential Public Health

Abstract Background Prior research examining the relationship between cannabis use, sedentary behavior, and physical activity has generated conflicting findings, potentially due to biases in the self-reported measures used to assess physical activity. This study aimed to more precisely explore the relationship between cannabis use and sedentary behavior/physical activity using objective measures. Methods Data were obtained from the 2005–2006 National Health and Nutrition Examination Survey. A total of 2,092 participants (ages 20–59; 48.8% female) had accelerometer-measured sedentary behavior, light physical activity, and moderate-to-vigorous physical activity. Participants were classified as light, moderate, frequent, or non-current cannabis users depending on how often they used cannabis in the previous 30 days. Multivariable linear regression estimated minutes in sedentary behavior/physical activity by cannabis use status. Logistic regression modeled self-reported moderate-to-vigorous physical activity in relation to current cannabis use. Results Fully adjusted regression models indicated that current cannabis users’ accelerometer-measured sedentary behavior did not significantly differ from non-current users. Frequent cannabis users engaged in more physical activity than non-current users. Light cannabis users had greater odds of self-reporting physical activity compared to non-current users. Conclusions This study is the first to evaluate the relationship between cannabis use and accelerometer-measured sedentary behavior and physical activity. Such objective measures should be used in other cohorts to replicate our findings that cannabis use is associated with greater physical activity and not associated with sedentary behavior in order to fully assess the potential public health impact of increases in cannabis use.

scholarly journals Physical Activity and the Risk of COVID-19 Infection and Mortality: A Nationwide Population-Based Case-Control Study

2021 ◽  
Vol 10 (7) ◽  
pp. 1539
Author(s):  
Dong-Hyuk Cho ◽  
Sun Ju Lee ◽  
Sae Young Jae ◽  
Woo Joo Kim ◽  
Seong Jun Ha ◽  
...  
Keyword(s):  
Physical Activity ◽  
Lower Risk ◽  
Population Based ◽  
Control Group ◽  
Metabolic Equivalent ◽  
South Korean ◽  
Public Health Screening ◽  
Metabolic Equivalent Of Task ◽  
Korean National Health Insurance ◽  
Respiratory Coronavirus

Regular physical activity (PA) is known to reduce the risk of serious community-acquired infections. We examined the association of PA with the morbidity and mortality resulting from coronavirus disease (COVID-19) infection in the South Korean population. Patients who tested positive for severe acute respiratory coronavirus 2 and who underwent public health screening between 2014 and 2017 (n = 6288) were included. Age- and sex-matched controls (n = 125,772) were randomly selected from the Korean National Health Insurance Service database. Leisure-time PA was assessed using a self-reported questionnaire. The mean PA levels were lower in the patient than in the control group (558.2 ± 516.3 vs. 580.2 ± 525.7 metabolic equivalent of task (MET)-min/week, p = 0.001). Patients with moderate to vigorous PA (MVPA) were associated with a lower risk of COVID-19 morbidity (odds ratio (OR), 0.90; 95% confidence interval (CI), 0.86–0.95). In addition, a standard deviation (SD) increment in MET/week (525.3 MET-min/week) was associated with a 4% decrease in the risk of COVID-19 morbidity (OR, 0.96; 95% CI, 0.93–0.99). MVPA and an SD increment in MET/week were associated with lower mortality (MVPA: OR, 0.47; 95% CI, 0.26–0.87; per SD increment: OR, 0.65; 95% CI, 0.48–0.88). Higher levels of regular PA were associated with a lower risk of COVID-19 infection and mortality, highlighting the importance of maintaining appropriate levels of PA along with social distancing amid the COVID-19 pandemic.

scholarly journals Relationship between NAFLD and Periodontal Disease from the View of Clinical and Basic Research, and Immunological Response

2021 ◽  
Vol 22 (7) ◽  
pp. 3728
Author(s):  
Masahiro Hatasa ◽  
Sumiko Yoshida ◽  
Hirokazu Takahashi ◽  
Kenichi Tanaka ◽  
Yoshihito Kubotsu ◽  
...  
Keyword(s):  
Risk Factor ◽  
Periodontal Disease ◽  
Alveolar Bone ◽  
Basic Research ◽  
Epidemiological Studies ◽  
Cross Sectional ◽  
Periodontopathic Bacteria ◽  
In Vivo Animal Model ◽  
The Relationship

Periodontal disease is an inflammatory disease caused by pathogenic oral microorganisms that leads to the destruction of alveolar bone and connective tissues around the teeth. Although many studies have shown that periodontal disease is a risk factor for systemic diseases, such as type 2 diabetes and cardiovascular diseases, the relationship between nonalcoholic fatty liver disease (NAFLD) and periodontal disease has not yet been clarified. Thus, the purpose of this review was to reveal the relationship between NAFLD and periodontal disease based on epidemiological studies, basic research, and immunology. Many cross-sectional and prospective epidemiological studies have indicated that periodontal disease is a risk factor for NAFLD. An in vivo animal model revealed that infection with periodontopathic bacteria accelerates the progression of NAFLD accompanied by enhanced steatosis. Moreover, the detection of periodontopathic bacteria in the liver may demonstrate that the bacteria have a direct impact on NAFLD. Furthermore, Porphyromonas gingivalis lipopolysaccharide induces inflammation and accumulation of intracellular lipids in hepatocytes. Th17 may be a key molecule for explaining the relationship between periodontal disease and NAFLD. In this review, we attempted to establish that oral health is essential for systemic health, especially in patients with NAFLD.

scholarly journals Leisure-time physical activity and endometrial cancer risk: Dose-response meta-analysis of epidemiological studies

2014 ◽  
Vol 135 (3) ◽  
pp. 682-694 ◽  
Author(s):  
NaNa Keum ◽  
Woong Ju ◽  
Dong Hoon Lee ◽  
Eric L. Ding ◽  
Chung C. Hsieh ◽  
...  
Keyword(s):  
Physical Activity ◽  
Endometrial Cancer ◽  
Cancer Risk ◽  
Dose Response ◽  
Leisure Time ◽  
Leisure Time Physical Activity ◽  
Meta Analysis ◽  
Epidemiological Studies ◽  
Endometrial Cancer Risk

scholarly journals Can Physical Activity While Sedentary Produce Health Benefits? A Single-Arm Randomized Trial

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Marvin A. Sackner ◽  
Jose R. Lopez ◽  
Veronica Banderas ◽  
Jose A. Adams
Keyword(s):  
Physical Activity ◽  
Oxygen Consumption ◽  
Physical Inactivity ◽  
Health Benefits ◽  
Metabolic Equivalent ◽  
Behavior Change Interventions ◽  
Supine Posture ◽  
Metabolic Equivalent Of Task ◽  
Seated Posture

Abstract Background Sedentary time poses a risk to health. Substituting physical activity for inactivity is obvious but this requires a behavior change. Interventions advocated to decrease uninterrupted physical inactivity (defined as Metabolic Equivalent of Task (METS) less than 1.5) are important. One such intervention is accomplished with the Gentle Jogger (GJ), a low risk motorized wellness device which produces effortless, rapid motion of the lower extremities simulating locomotion or fidgeting. GJ produces health benefits in type 2 diabetes, heart disease, and high blood pressure. The purpose of this trial was to ascertain whether GJ increases METS above 1.5 to explain its effectiveness despite sedentary behavior or whether tapping is responsible. Methods A randomized single-arm trial was conducted. Subjects were randomized to begin the study in either the supine or seated postures and on the same day crossed over with the starting posture reversed. Oxygen consumption was measured at rest and during GJ. Results Twenty-six subjects were studied (15 women and 11 men) with a mean age of 44 ± 15 years and BMI 27.9 ± 5.0, 19 were overweight or obese, and 7 had normal BMI. GJ increased oxygen consumption and METS 15% in the seated posture and 13% in the supine posture. No individual receiving GJ achieved METS exceeding 1.5. Conclusions In a moderately obese population, GJ in seated or supine posture did not exceed 1.5 METS. The values are comparable to those reported for sit-stand interventions and cannot explain the health benefits of GJ. Trial registration ClinicalTrials.gov, NCT03602365. Registered on July 26, 2018

Relating Lifetime Activity Behavior to the Current Level of Physical Activity of Older Adults

2020 ◽  
pp. 1-7
Author(s):  
Oliver Vogel ◽  
Daniel Niederer ◽  
Jan Wilke ◽  
Maike Steinmann ◽  
Lutz Vogt
Keyword(s):  
Physical Activity ◽  
Older Adults ◽  
Community Dwelling ◽  
Activity Levels ◽  
Estimation Errors ◽  
Metabolic Equivalent ◽  
Physical Activity Questionnaire ◽  
Metabolic Equivalent Of Task ◽  
Leisure Physical Activity ◽  
Activity Questionnaire

This study investigates methods of data gathering and management, along with the relationship of lifespan and older adults’ activity. Community-dwelling older adults (n = 47, 81.7 ± 3.6 years) completed the Lifetime Leisure Physical Activity Questionnaire. Current activity was assessed by use of accelerometers. The data were converted to the metabolic equivalent of task hours. Correlations between the main outcomes (metabolic equivalent of task/hour, Lifetime Leisure Physical Activity Questionnaire), as well as individual estimation errors for data adjustments, were computed. The accelerometer and Lifetime Leisure Physical Activity Questionnaire data for the last 12 months’ activity were associated (r = .31, p = .033). The average overestimation in the self-reported data was 176%. The adapted data on lifetime physical activity reveals correlations between older adults’ activity and the activity levels of three 15-year episodes (r = .354; r = .336; r = .323; each p < .05), as well as compliance with guidelines throughout life (Hotelling’s T2 = 45–164; p ≤ .002). Our findings indicate a relationship between lifetime and older adults’ activity and provide further support for lifelong engagement in physical activity.

scholarly journals Physical activity trajectories following gynecological cancer: results from a prospective, longitudinal cohort study

2020 ◽  
Vol 30 (11) ◽  
pp. 1784-1790
Author(s):  
Steven Fleming ◽  
Tamara Jones ◽  
Monika Janda ◽  
Dimitrios Vagenas ◽  
Leigh Ward ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Physical Activity ◽  
Endometrial Cancer ◽  
Gynecological Cancer ◽  
Activity Levels ◽  
Physical Activity Levels ◽  
Low Levels ◽  
The Relationship ◽  
Over Time

BackgroundParticipating in physical activity after a diagnosis of cancer is associated with reduced morbidity and improved outcomes. However, declines in, and low levels of, physical activity are well documented in the broader cancer population, but with limited evidence following gynecological cancer.ObjectiveTo describe physical activity levels from before and up to 2 years after gynecological cancer surgery; to explore the relationship between physical activity patterns and quality of life; and to describe characteristics associated with physical activity trajectories post-gynecological cancer.MethodsWomen with gynecological cancer (n=408) participated in a prospective study that assessed physical activity and quality of life pre-surgery (baseline), at 6 weeks, and 3, 6, 9, 12, 15, 18 and 24 months post-surgery. Validated questionnaires were used to assess physical activity (Active Australia Survey) and quality of life outcomes (Functional Assessment of Cancer Therapy-General). Generalized estimating equation modeling, group-based trajectory analysis, and analysis of variance were used to identify physical activity levels over time, to categorize women into physical activity trajectory groups, and to assess the relationship between physical activity levels and quality of life, respectively.ResultsWomen had a mean±SD age of 60±11.4 years at diagnosis, with the majority diagnosed with endometrial cancer (n=235, 58%) or stage I disease (n=241, 59%). Most women (80%) started with and maintained low levels of physical activity (1–10 metabolic equivalent task hours per week), reported no physical activity throughout the follow-up period, or reduced physical activity levels over time. Only 19% of women maintained or doubled physical activity levels, so that by 24 months post-diagnosis they were engaging in sufficient levels of physical activity. Women with endometrial cancer (58% of the sample) were more likely to be overweight or obese and to report low levels of physical activity or none at all. Higher physical activity levels were associated with higher quality of life (p<0.05).ConclusionThe low baseline and surveillance levels of physical activity show that the vast majority of gynecological cancer survivors have the ability to improve their physical activity levels. Integration of physical activity advice and support into standard care could lead to gains in quality of life during gynecological cancer survivorship.

scholarly journals Perceived Physical Activity Barriers in Relation To Depressive Symptoms in Overweight/Obese Latinos –The Adelgaza Trial.

2021 ◽  
Author(s):  
Caroline A. Figueroa ◽  
Adrian Aguilera ◽  
Yoshimi Fukuoka
Keyword(s):  
Physical Activity ◽  
Multivariate Regression ◽  
Depression Scale ◽  
Epidemiological Studies ◽  
Effect Estimate ◽  
Depression Treatment ◽  
Linear Effect ◽  
The Us ◽  
Post Hoc ◽  
The Relationship

Abstract Background Latinos are the most physically inactive population in the US and under-utilize depression treatment. Physical activity is a suitable depression treatment, but Latinos report high barriers. The relationship between perceived activity barriers and depression has not been assessed before in Latinos. Methods We included 54 overweight Latino participants, BMI > 24.9 kg/m2, 68.5% female, mean age 45.3 years, enrolled in a weight loss intervention–the Adelgaza trial. Using multivariate regression, we examined the association between the total Barriers to Being Active Quiz (BBAQ) and the Center for Epidemiological Studies Depression Scale (CES-D). We post-hoc assessed this relationship for the BBAQ subscale-scores. Results Depression scores were associated with barrier scores (linear effect, estimate = 0.73, p = 0.02). A lack of resources was significantly related to higher depression (post-hoc exploratory, OR = 1.56, p = 0.002). Conclusion Physical activity barriers and depression are related in overweight Latino/a men and women. Perceived lack of resources might be a particularly important depression-related barrier.

scholarly journals Cognitive impairment as a risk factor for psychosis

2005 ◽  
Vol 7 (1) ◽  
pp. 31-38 ◽  
Keyword(s):  
Risk Factor ◽  
Cognitive Impairment ◽  
Cognitive Functioning ◽  
Brain Function ◽  
Negative Symptoms ◽  
Psychotic Disorders ◽  
Epidemiological Studies ◽  
Psychotic Symptoms ◽  
Future Research ◽  
The Relationship

Since the time of Kraepelin and Bleuler, it has been recognized that schizophrenia is associated with a profound and persistent cognitive impairment. This paper reviews the major clinical and epidemiological studies of cognitive functioning in schizophrenia and other psychotic disorders, and presents several possible models to explain the association between cognitive impairment and psychosis. Cognitive impairment is present in the majority of patients with schizophrenia, and, in some, it is already evident in the premorbid stages of the disorder. This cognitive impairment is not secondary to psychotic symptoms, negative symptoms, or socioeconomic status. Cognitive impairment can also be observed in nonpsychotic family members of psychotic patients. On the basis of this evidence, it has been proposed that abnormal cognitive functioning can be considered as a possible causal risk factor for psychosis. Recent studies assessing the relationship between genetic background, cognition, brain function, and schizophrenia are presented here as an outline for future research.

Associations of physical activity with survival and progression in metastatic colorectal cancer: Results from CALGB 80405 (Alliance).

2017 ◽  
Vol 35 (4_suppl) ◽  
pp. 659-659 ◽  
Author(s):  
Brendan John Guercio ◽  
Alan P. Venook ◽  
Donna Niedzwiecki ◽  
Sui Zhang ◽  
Kaori Sato ◽  
...  
Keyword(s):  
Physical Activity ◽  
Colorectal Cancer ◽  
Metastatic Colorectal Cancer ◽  
Progression Free Survival ◽  
Self Report ◽  
Phase Iii ◽  
Metabolic Equivalent ◽  
Activity Assessment ◽  
Chemotherapy Initiation ◽  
Reduced Risk

659 Background: Regular physical activity (PA) is associated with reduced risk of recurrence and mortality in non-metastatic colorectal cancer. Its influence on patients with metastatic colorectal cancer (mCRC) is largely unexplored. Methods: 1231 patients participating in CALGB 80405 (first-line phase III chemotherapy trial for mCRC) completed questionnaires that included self-report on PA at time of chemotherapy initiation and total metabolic equivalent task (MET)-hours/week were determined based on responses. The primary endpoint of the clinical trial and this companion study was overall survival (OS), with progression-free survival (PFS) as a secondary endpoint. To minimize confounding by poor and rapidly declining health, we excluded patients who experienced progression or died within 60 days of activity assessment and adjusted for known prognostic factors, comorbid illness, and weight loss over the previous six months. Results: Compared with patients engaged in less than three MET-hours/week of PA, patients engaged in 18 or more MET-hours/week experienced an adjusted hazard ratio for OS of 0.81 (95% CI 0.67 to 0.98, P for trend 0.03) and for PFS of 0.84 (95% CI 0.71 to 1.00, P for trend 0.03). Greater nonvigorous PA and walking duration were both associated with improved OS ( P for trend 0.01 and 0.04, respectively). Conclusions: In mCRC patients from CALGB 80405, greater total PA was associated with improved PFS and OS, while greater walking duration and non-vigorous PA were associated with reduced risk of all-cause mortality. Support: U10CA180821, U10CA180882. ClinicalTrials.gov ID: NCT00265850 [Table: see text]

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