scholarly journals An Overview on Saccharomyces cerevisiae Indigenous Strains Selection Methods

2021 ◽  
Author(s):  
Laura Pulcini ◽  
Elisa Gamalero ◽  
Antonella Costantini ◽  
Enrico Tommaso Vaudano ◽  
Christos Tsolakis ◽  
...  

From the fundamental studies of Louis Pasteur in the XIX century to the current genomic analysis, the essential role of microorganisms in winemaking industry is well recognised. In the last decades, selected Saccharomyces cerevisiae strains with excellent fermentative behaviour have been widely commercialised in form of active dry yeasts. Currently, the production of organic and “natural” wines represents a new economically relevant trend in the wine sector. Based on this market demand, the use of industrial yeast starter could be perceived as non-organic practice and then, rejected. However, in order to preserve wines sensory quality, healthiness, and to avoid organoleptic defects given by undesirable microorganisms, the “yeast factor” (S. cerevisiae or non-Saccharomyces) cannot be ignored. The purpose of this chapter is to describe the methods of selection of wine yeasts focusing the attention on indigenous S. cerevisiae strains. In fact, the use of ecotypic yeasts may represent a good compromise between the needs of microbiologically controlled fermentation and a modern vision of wine as natural expression of its “terroir”, also from the microbiological point of view.

2001 ◽  
Vol 13 (1) ◽  
pp. 21-28
Author(s):  
B. Van Houdenhove

SUMMARYChronic pain is a phenomenon with important psychiatric aspects from a diagnostic as well as a therapeutic point of view. The place of chronic pain in the different versions of the Diagnostic and Statistical Manual of Mental Disorders, and the differential-diagnosis are critically discussed. The comorbidity with depression, anxiety disorders, substance abuse and personality disorders is extensively treated. Finally, the essential role of the psychiatrist in the multidisciplinary therapeutic approach of these patients is emphasised.


PLoS ONE ◽  
2015 ◽  
Vol 10 (3) ◽  
pp. e0122382 ◽  
Author(s):  
Roberto Pérez-Torrado ◽  
Silvia Llopis ◽  
Benedetta Perrone ◽  
Rocío Gómez-Pastor ◽  
Bernhard Hube ◽  
...  

2013 ◽  
Vol 6 (1) ◽  
pp. 48 ◽  
Author(s):  
Daniel González-Ramos ◽  
Marcel van den Broek ◽  
Antonius JA van Maris ◽  
Jack T Pronk ◽  
Jean-Marc G Daran

2020 ◽  
Vol 295 (6) ◽  
pp. 1489-1500
Author(s):  
Gregor W. Schmidt ◽  
Niek Welkenhuysen ◽  
Tian Ye ◽  
Marija Cvijovic ◽  
Stefan Hohmann

Abstract Glucose, fructose and mannose are the preferred carbon/energy sources for the yeast Saccharomyces cerevisiae. Absence of preferred energy sources activates glucose derepression, which is regulated by the kinase Snf1. Snf1 phosphorylates the transcriptional repressor Mig1, which results in its exit from the nucleus and subsequent derepression of genes. In contrast, Snf1 is inactive when preferred carbon sources are available, which leads to dephosphorylation of Mig1 and its translocation to the nucleus where Mig1 acts as a transcription repressor. Here we revisit the role of the three hexose kinases, Hxk1, Hxk2 and Glk1, in glucose de/repression. We demonstrate that all three sugar kinases initially affect Mig1 nuclear localization upon addition of glucose, fructose and mannose. This initial import of Mig1 into the nucleus was temporary; for continuous nucleocytoplasmic shuttling of Mig1, Hxk2 is required in the presence of glucose and mannose and in the presence of fructose Hxk2 or Hxk1 is required. Our data suggest that Mig1 import following exposure to preferred energy sources is controlled via two different pathways, where (1) the initial import is regulated by signals derived from metabolism and (2) continuous shuttling is regulated by the Hxk2 and Hxk1 proteins. Mig1 nucleocytoplasmic shuttling appears to be important for the maintenance of the repressed state in which Hxk1/2 seems to play an essential role.


Episteme ◽  
2008 ◽  
Vol 5 (1) ◽  
pp. 74-93 ◽  
Author(s):  
Michael Fuerstein

ABSTRACTHow can democratic governments be relied upon to achieve adequate political knowledge when they turn over their authority to those of no epistemic distinction whatsoever? This deep and longstanding concern is one that any proponent of epistemic conceptions of democracy must take seriously. While Condorcetian responses have recently attracted substantial interest, they are largely undermined by a fundamental neglect of agenda-setting. I argue that the apparent intractability of the problem of epistemic adequacy in democracy stems in large part from a failure to appreciate the social character of political knowledge. A social point of view brings into focus a number of vital factors that bear on our understanding of democratic epistemology and our assessment of its prospects: the essential role of inclusive deliberation, the public's agenda-setting function, institutional provisions for policy feedback, the independence of expert communities, and the knowledge-pooling powers of markets.


2014 ◽  
Vol 5 (1) ◽  
Author(s):  
Janelle C. Arthur ◽  
Raad Z. Gharaibeh ◽  
Marcus Mühlbauer ◽  
Ernesto Perez-Chanona ◽  
Joshua M. Uronis ◽  
...  

2019 ◽  
Vol 6 (11) ◽  
pp. 509-523 ◽  
Author(s):  
Patrícia Lage ◽  
Belém Sampaio-Marques ◽  
Paula Ludovico ◽  
Nuno P. Mira ◽  
Ana Mendes-Ferreira

2020 ◽  
pp. 108-118

Globally, the pandemic installed by the coronavirus has led to a change in the way business is conducted. In the context of the economic crisis knocking on the door, the states of the world are trying to take the most severe measures to mitigate the effects of this epidemic. One sector of the economy that needs to be protected is agriculture, because it provides the much-needed food for everyone. The role of farmers is very important in this equation, as they provide the necessary food stabilizing stocks of food that can be depleted faster. In this paper we want to determine the possible impact that the drought and the overlap of the COVID pandemic on it may have on the prices of agricultural products of animal origin in Romania. In this context, the level of prices in the first half of the previous year was compared with the level of prices in the first half of the current year, in order to be able to determine, from a statistical point of view, whether there are significant differences. It was found that for five of the six products analyzed, the prices in the first half of 2020 were higher than in the first half of 2019. Following this analysis, the correlation coefficients between the price level and the precipitation level were determined, and subsequently between the price level and the market demand, the latter influenced by the pandemic. It was found that both phenomena indirectly influenced the prices of agricultural products of animal origin.


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