scholarly journals A REVIEW ON BASTI CHIKITSA IN PRAMEHA: A CRITICAL ANALYSIS

2021 ◽  
Vol 12 (5) ◽  
pp. 110-114
Author(s):  
Suma K J ◽  
Meghana N ◽  
Shalini C
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Secretion ◽  
Blood Glucose ◽  
Metabolic Disorder ◽  
Critical Analysis ◽  
Insulin Action ◽  
Adult Population ◽  
Main Line ◽  
Daytime Sleep ◽  
Lack Of Exercise

Prameha is a Tridoshaja Vyadhi with Kapha predominance. It is a lifestyle disorder and Charaka explains it as a Santarpana Janya Vyadhi, caused due to overindulgence in heavy and richly nutritious food, daytime sleep, lack of exercise, other sedentary habits and not doing seasonal purification. All these etiological factors are responsible for the formation of Vitiated Meda and Kleda (deliquesce) i.e. Abhishyanda. The disease is mainly characterized by Prabhuta and Avila Mutrata. Prameha can be correlated with Diabetes Mellitus. Diabetes mellitus is a metabolic disorder of multiple aetiology, characterized by an increase in plasma blood glucose resulting from defects in insulin secretion, insulin action, or both. Globally, an estimated 463 million adults are living with Diabetes. Diabetes Currently affects more than 62 million people which is more than 7.1% of India’s adult population. As Prameha is a Santarpana Janya Vyadhi, Apatarpana is the main line of treatment. Charaka explains various Shodhana procedures in Prameha and contraindicates Basti in it, as it will increase the progress of the disease. But still, Acharyas explain various Basti Karmas for Prameha. Hence here is an attempt to critically analyse Basti Karma as a line of treatment in Prameha.

scholarly journals A Review on Ethno-pharmacology of Antidiabetic Plants

2018 ◽  
pp. 1-22
Author(s):  
M. A. Omoirri ◽  
O. M. Odigie ◽  
K. O. Gbagbeke ◽  
I. F. Ajegi ◽  
J. O. Oseyomon ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Secretion ◽  
Blood Glucose ◽  
Side Effects ◽  
Medicinal Plants ◽  
Metabolic Disorder ◽  
Developing Nations ◽  
Active Components ◽  
Treatment Of Diabetes ◽  
Antidiabetic Plants

Abnormally emanates from difficulty in insulin secretion, Diabetes mellitus (DM) is known to be a metabolic disorder that causes an increase of blood glucose in blood streams. The lack of effective modern treatments, the lifelong treatment with modern medicines, overtime, its associated health side effects, and its expensive prices among others are the challenging existing realities that devastate the health and economic burdens its sufferers, especially in developing nations. Today, this has prompted the search for cheap, safe, and reliable drugs from medicinal plants. This study reviewed existing information on medicinal plants used for the treatment of diabetes mellitus from various sources. Several documents (published and unpublished papers, books among others) were consulted in compilation of this review. It is found that there is a wide, yet uneven support for active components of major medicinal.

A Critical Review on Madhumeha (Diabetes Mellitus) with its Preventive Approach

2017 ◽  
Vol 2 (05) ◽  
Author(s):  
Anagha Gosavi ◽  
Ram V. Ramekar
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Secretion ◽  
Protein Metabolism ◽  
Insulin Action ◽  
Preventive Measures ◽  
Sweet Taste ◽  
Whole Body ◽  
Appropriate Use ◽  
Chronic Hyperglycemia ◽  
Therapeutic Measures

Prameha is disease of Mutravaha Srotasa having Kapha dominancy which can be correlated with diabetes mellitus. The term diabetes mellitus describes a metabolic disorder of multiple etiologies characterized by chronic hyperglycemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both. Madhumeha is considered as a subtype under the Vatika type of Prameha and it is characterized by passage of urine with sweet taste like honey along with sweetness of whole body. With appropriate use of Ayurvedic preventive measures such as Dincharya, Ritucharya, Aharvidhi and therapeutic measures Madhumeha (DM) can be prevented.

scholarly journals Diabetes mellitus and impaired glucose tolerance in urban adult population

2014 ◽  
Vol 60 (2) ◽  
pp. 118-124 ◽  
Author(s):  
Walter Rodrigues Júnior ◽  
Sandra Cristina Nicodemo Gaban ◽  
Elenir Rose Jardim Cury Pontes ◽  
Celso Correia Souza ◽  
Lilian Patussi Gimenes ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Glucose Tolerance ◽  
Impaired Glucose Tolerance ◽  
Adult Population ◽  
Oral Glucose ◽  
Diabetic Patients ◽  
Mato Grosso ◽  
Strict Adherence ◽  
Family History Of Diabetes

Objective: Estimating the prevalence of diabetes mellitus (DM) and impaired glucose tolerance (IGT) in the urban population aged between 30 and 69 years in the municipality of Campo Grande, state of Mato Grosso do Sul, Brazil. Methods: Population-based cross-sectional study conducted between October/2009 and February/2011. The investigation included the determination of fasting glucose and participants with blood glucose ≥ 200 mg/dL were considered diabetic. Nondiabetic patients, which showed blood glucose ≥ 100 mg/dL and < 200 mg/dL, underwent an oral glucose tolerance test (OGTT) to investigate whether they had DM or IGT. Results: 1.429 individuals participated in this investigation. The general prevalence, adjusted for sex and age, were: 12.3% for DM (95%CI: 10.5 to 13.9%) and 7.1% for IGT (95%CI: 5.7 to 8.4%). There was a higher prevalence of DM with increasing age in people with low educational level, family history of diabetes, overweight, obesity and central obesity. Among diabetic patients (n = 195), 25% were unaware they had the disease and were diagnosed through investigation. Among patients who already knew they had DM (n = 146), 37% were unaware of the potential chronic complications. Conclusion: This study confirms the increased prevalence of DM in Brazil and emphasizes the need for early diagnosis, as well as the importance of strict adherence to medical treatment in order to prevent its much feared complications.

scholarly journals The impact of dietary protein restriction on insulin secretion and action

1999 ◽  
Vol 58 (3) ◽  
pp. 647-653 ◽  
Author(s):  
Mark J. Holness
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Insulin Secretion ◽  
Insulin Action ◽  
Synergistic Effects ◽  
Protein Restriction ◽  
Dependent Diabetes Mellitus ◽  
Organ Systems ◽  
The Impact

The goal of this review is to develop the hypothesis, and review the evidence, that protein restriction, through synergistic effects on multiple organ systems predisposes to loss of normal regulation of fuel homeostasis that plays the central role in the development of type 2 (non-insulin-dependent) diabetes mellitus. The ability of insulin to regulate glucose production and disposal varies between individuals. These differences, together with the various compensatory mechanisms that are invoked to attempt to normalize fuel homeostasis, are of fundamental importance in the development and clinical course of type 2 diabetes mellitus. Protein deprivation impacts on both insulin secretion and insulin action. These effects may persist even when a diet containing adequate protein is presented subsequently. Data are presented that suggest that protein restriction results in an impaired ability of pancreatic β-cells to compensate adequately for the defect in insulin action in insulin-resistant individuals. This persistent impairment of insulin secretion resulting from protein restriction predisposes to loss of glucoregulatory control and impaired insulin action after the subsequent imposition of a diabetogenic challenge. This inability to maintain the degree of compensatory hyperinsulinaemia necessary to prevent loss of glucose tolerance may have relevance to the increased incidence of diabetes on changing from a nutritionally-poor diet to a Western diet, and to the hypothesis that some cases of type 2 diabetes in adulthood may be related to poor early nutrition.

scholarly journals Oral Alterations in Diabetes Mellitus

2018 ◽  
Vol 22 (1) ◽  
pp. 7-14 ◽  
Author(s):  
Smiljka Cicmil ◽  
Irena Mladenović ◽  
Jelena Krunić ◽  
Dragan Ivanović ◽  
Nikola Stojanović
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Secretion ◽  
Insulin Action ◽  
Metabolic Diseases ◽  
Dental Treatment ◽  
Current Knowledge ◽  
Dental Health ◽  
The Third ◽  
Oral Tissue ◽  
Compromised Patients

SummaryDiabetes mellitus is one of the most common chronic diseases which continue to increase in number and significance. It presents the third most prevalent condition among medically compromised patients referring for dental treatment. Diabetes mellitus has been defined as a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. Hyperglycemia leads to widespread multisystem damage which has an effect on oral tissue. The present article summarizes current knowledge regarding the association between diabetes mellitus and oral and dental health.

scholarly journals L-Tryptophan Suppresses Rise in Blood Glucose and Preserves Insulin Secretion in Type-2 Diabetes Mellitus Rats

2012 ◽  
Vol 58 (6) ◽  
pp. 415-422 ◽  
Author(s):  
Tomoko INUBUSHI ◽  
Norio KAMEMURA ◽  
Masataka ODA ◽  
Jun SAKURAI ◽  
Yutaka NAKAYA ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Insulin Secretion ◽  
Blood Glucose

scholarly journals Monitoring of Patient With Diabetes Mellitus

2017 ◽  
Vol 3 (2) ◽  
pp. 55
Author(s):  
Widodo Widodo
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Secretion ◽  
Blood Vessels ◽  
Insulin Action ◽  
Laboratory Tests ◽  
Impaired Insulin Secretion ◽  
Chronic Hyperglycemia ◽  
Impaired Insulin ◽  
Patients With Diabetes ◽  
Impaired Insulin Action

Diabetes mellitus is a disease characterized by hyperglycemia, which is caused by impaired insulin secretion, impaired insulin action, or both. Chronic hyperglycemia will lead to dysfunction and damage to various organs, such as the eyes, kidneys, nerves, heart, and blood vessels. This paper discusses the monitoring of patients with diabetes mellitus according to the laboratory tests, to know when the results of therapy has reached the optimum point as well as the prevention of complications that can occur.  

scholarly journals New Aspects of Cellular Cholesterol Regulation on Blood Glucose Control—Review and Perspective on the Impact of Statin Medications on Metabolic Health

2017 ◽  
Vol 13 (02) ◽  
pp. 63
Author(s):  
Brian A Grice ◽  
Jeffrey S Elmendorf ◽  
◽  
Keyword(s):  
Insulin Secretion ◽  
Blood Glucose ◽  
Glucose Metabolism ◽  
Pancreatic Beta Cells ◽  
Insulin Action ◽  
Cholesterol Metabolism ◽  
Blood Glucose Control ◽  
Metabolic Health ◽  
Cellular Cholesterol ◽  
The Impact

Cholesterol is an essential component of cell membranes, and during the past several years, diabetes researchers have found that membrane cholesterol levels in adipocytes, skeletal muscle fibers and pancreatic beta cells influence insulin action and insulin secretion. Consequently, it is thought that dysregulated cell cholesterol homeostasis could represent a determinant of type 2 diabetes (T2D). Recent clinical findings compellingly add to this notion by finding increased T2D susceptibility in individuals with alterations in a variety of cholesterol metabolism genes. While it remains imperfectly understood how statins influence glucose metabolism, the fact that they display an influence on blood glucose levels and diabetes susceptibility seems to intensify the emerging importance of understanding cellular cholesterol in glucose metabolism. Taking this into account, this review first presents cell system and animal model findings that demonstrate the negative impact of cellular cholesterol accumulation or diminution on insulin action and insulin secretion. With this framework, a description of how changes in cholesterol metabolism genes are associated with T2D susceptibility will be presented. In addition, the connection between statins and T2D risk will be reviewed with expanded information on pitavastatin, a newer statin medication that displays actions favoring metabolic health.

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