Validation of the Geriatric Anxiety Inventory in younger adults

This study investigated the psychometric properties of the Geriatric Anxiety Inventory (GAI) in younger adults. Participants were 212 younger adults age M = 22 (range = 17–53) years. They completed a demographic information questionnaire and self-report measures: the GAI, the Depression Anxiety Stress Scales (DASS), the Generalized Anxiety Disorder–7 (GAD-7), the Patient Health Questionnaire–9 (PHQ-9), the Penn State Worry Questionnaire (PSWQ), and the Worry Behaviors Inventory (WBI). Data from the GAI were collected at two time points, one week apart, and data from other self-report measures were collected once via Qualtrics, an online survey platform. The internal consistency and test–retest score reliability of the GAI were excellent. It had good congruent validity with other anxiety measures, limited divergent validity with depression measures, and sound convergent validity with worry measures. The GAI showed good discrimination between probable cases and noncases of generalized anxiety disorder (participants who scored ⩾8 on the GAD-7) and its optimal cutoff score for probable cases of GAD was ⩾12. A unidimensional component structure of the GAI best fit this study’s data. This study has provided preliminary evidence that the GAI is reliable and valid for use in an Australian sample of younger adults.

Nurses’ Attitudes Towards Death and Its Relationship With Anxiety Levels

This study examined nurses’ attitudes towards death, anxiety levels, and socio-demographic characteristics affecting their attitudes towards death. Three hundred and eighty-four nurses participated in the study. A questionnaire form, the Death Attitude Profile-Revised (DAP-R), and the Penn State Worry Questionnaire were applied to the nurses. Nurses’ attitudes towards death were positive and their level of fear of death was low. Approach acceptance was high in younger ones; the escape acceptance score was higher in single ones. The neutral acceptance score was higher in those who received training on death. A statistically significant positive correlation was found between nurses' anxiety level and escape acceptance score. There was a statistically significant positive correlation between the length of working years of nurses and the escape acceptance and approach acceptance. Nurses should be prepared for and supported on death with in-service training. It will be useful to provide these training programs to nursing students during their education process.

Care Recipient Diagnosis Moderates the Relationship Between Caregiver Worry and Vigilance

Family members of persons diagnosed with dementia or a traumatic brain injury (TBI) are often relied upon to provide daily support to their care recipients. However, research on the differing experiences of caregivers based on care recipient diagnosis is limited. The aim of this study was to examine the impact of worry and feelings of vigilance among caregivers of people with cognitive impairment due to either TBI or dementia. This sample included 61 caregivers (88.5% female, mean age 57.3±15.5) of persons with either a TBI (n = 32) or dementia (n = 29). Worry was assessed with the Penn State Worry Questionnaire and Vigilance was assessed with the Caregiver Vigilance Scale. Linear regressions revealed that after controlling for age, care recipient diagnosis moderated the relationship between worry and caregiver vigilance. Specifically, worry was significantly associated with caregiver vigilance in those caring for someone with dementia; however, a similar relationship was not seen in those caring for someone with a TBI. This suggests caregivers of people with TBIs have a different experience of worry and vigilance than caregivers of people with dementia. These findings demonstrate the need for more research on the unique needs of caregivers of people with TBIs. Additionally, this research suggests interventions targeting worry may be particularly effective in supporting caregivers of people with TBIs.

Cross-Cultural and Gender Invariance of Five Common Symptom and Cognitive Vulnerability Measures in the United States and Singapore

Reliable and valid measurements of anxiety, chronic worry, depressive, and obsessive-compulsive symptoms is essential when seeking to draw cross-cultural and gender comparisons. Accordingly, the current study determined the psychometric properties of five widely used symptom measures in the United States (U.S.) and Singapore (SG) and across gender: Beck Anxiety Inventory (BAI), Beck Depression Inventory-II (BDI-II), Obsessive Beliefs Questionnaire (OBQ), Obsessive-Compulsive Inventory-Revised (OCI-R), and the Penn State Worry Questionnaire-Abbreviated (PSWQ-A). Participants comprised college students (U.S.: n = 292; SG: n = 144). Strict measurement invariance (equal factor loadings, item thresholds, residual variances) was observed for all measures across cultures and genders, except for the BAI, which met partial Level 1 strict cross-gender invariance. Overall, findings suggest a strong degree of cross-cultural and cross-gender construct compatibility, but also point to some notable exceptions, thereby providing ample material for theory-building and future research on transdiagnostic symptom and cognitive vulnerability measures across diverse groups.

Psychometric Properties of the Persian Version of General Emotion Questionnaire-Contrast Avoidance Model

Background: According to Contrast Avoidance Model, those suffering from generalized anxiety disorder (GAD) are afraid of severe emotional changes such as the transition from a good or neutral position to sudden unhappiness following a negative event. Also, the model shows that persistent worrying can be used to maintain negative emotions as a means of preventing a sudden change to negative in people with GAD. Objectives: This study aimed to evaluate the psychometric properties of the Persian version of the General Emotion Questionnaire-Contrast Avoidance Model (GEQ-CAM). Methods: Early, the GEQ was translated into Persian according to the translation instructions and using multistage cluster sampling. Initially, five universities located in Tehran were randomly selected, then from each of them, three different colleges were selected for the academic year of 2020. Afterward, 50 cases with GAD were selected using the convenience sampling method, yielding a total sample size of 576 (526 students and 50 cases with GAD). Results: General Emotion Questionnaire has an excellent level of internal consistency (α = 0.973) and test-retest reliability (0.986). This questionnaire indicated a positive and significant correlation with Penn State Worry Questionnaire (r = 0.804) and GAD-7 (r = 0.727), which indicates its appropriate convergent validity. Also, confirmatory factor analysis supported its 2-factor structure. Conclusions: In accordance with previous studies, the findings suggested that psychometric properties of the Persian version of the General Emotion Questionnaire-Contrast Avoidance Model are acceptable; hence, this questionnaire can be used for research, diagnostic, and therapeutic purposes.

What’s Worrying Our Students? Increasing Worry Levels over Two Decades and a New Measure of Student Worry Frequency and Domains

Background The frequency and severity of mental health problems in student populations have been a growing cause for concern worldwide, and studies have identified measures of a number of mental health symptoms that have been steadily increasing in frequency and intensity over the past 20–25 years. Methods In two studies we investigate the levels and domains of pathological worrying in university student participants. Study 1 is a retrospective study of Penn State Worry Questionnaire (PSWQ) data collected between 2001 and 2019. Study 2 describes the development of the Student Worry Questionnaire, a short and easily delivered measure of student worrying that identifies both frequency of worry as well as the student-relevant domains across which worrying occurs. Results Study 1 revealed a steady increase in student worry scores of around 20% between 2001 and 2019, with a significant positive correlation between year of data collection and mean PSWQ score. The domain scores in Study 2 indicated that academic work was a significantly higher worry than any of the other domains, and worries about intimate relationships and ‘what people think of me’ were also worries that scored higher than either financial or health worries. Conclusions The present studies indicate that pathological worrying can be added to the list of anxiety- and stress-related symptoms that have been shown to be on the increase in student populations in recent decades, and we discuss whether these increases represent a greater willingness to report symptoms or a genuine increase in experienced symptoms over time.

The Impacts of Propensity to Worry and Fear of COVID-19 on Mental Health of University Students

Epidemics and pandemics are difficult periods for the affected community, specifically in the proliferation of mental health issues. In such adverse times, factors of psychological vulnerability such as propensity to worry and low emotional stability might have a detrimental effect on the mental health of the individuals. To investigate the impact of such factors on mental health, this study examined the impacts of propensity to worry and fear of COVID-19 on anxiety depending on the individuals’ levels of emotional stability. As a means of such investigation, this study was conducted based on quantitative data, and the research sample was selected using a convenient sampling method. Participants included 304 university students (71.6% were women and 28.4% were men; MAge = 22.37 ± 3.04) and responded to the Penn State Worry Questionnaire, Fear of COVID-19 Scale, Symptom Checklist-90 Revised, and 10-Item Personality Inventory. The moderated mediation analysis using PROCESS macro (Model 14) was performed to examine the study hypotheses. Results revealed that propensity to worry was associated with anxiety symptoms. Fear of COVID-19 mediated this link and emotional stability moderated the relationship between propensity to worry and anxiety. The findings showed that trait worry, trait emotional stability, and fear of COVID-19 are determinants of anxiety symptoms, suggesting that such factors are important in understanding these issues.

Impact of Human–Animal Interactions on Psychological and Physiological Factors Associated With Veterinary School Students and Donkeys

There has been an increased interest in evaluating human–animal interactions and assessing the mutual health and wellbeing. In this study, first-year female and male veterinary school students not paired (n = 58) or paired (n = 25) with immature (≤9 mo) donkeys (n = 13) were engaged in three different types of interactions (1st, hands-off remote learning, 2nd, hands-on passive learning, and 3rd, hands-on active learning) for 30 min each during Week 2 (Time 1), Weeks 5–8 (Time 2), and Week 12 (Time 3) over three, 15-week periods. Student psychological data involved the Penn State Worry Questionnaire (PSWQ) scores collected from the interactive (student-donkey pairs) and non-interactive (no student-donkey pairs) groups and modified Comfort from Companion Animals Scale (CCAS) scores collected from the interactive group during Times 1, 2, and 3. Donkey physiological data involved collection of saliva within 10 min pre- and post-interaction during Times 1, 2, and 3 in association with the different types of interactions for immunoanalysis of cortisol. There were no significant effects of the various times and types of interactions on CCAS scores. While there were no significant effects of group and types of interactions on PSWQ scores, there was an effect (P = 0.01) of time. Overall mean PSWQ scores were significantly lower during Week 12 versus Week 2. Correspondingly, while there were no effects pre- vs. post-interaction within or among times on saliva cortisol concentrations in donkeys, there was an effect (P = 0.02) of the type of interaction. Mean concentrations were significantly lower with the hands-on passive and hands-on active learning versus the hands-off remote learning. In conclusion, while this study provides preliminary evidence surrounding student donkey interactions, future studies are required with more comprehensive designs to clarify these benefits and better understand the advantages and challenges surrounding student-donkey interactions.

Associations of Thyroid Hormones Profile During Normal Pregnancy and Postpartum With Anxiety, Depression, and Obsessive/Compulsive Disorder Scores in Euthyroid Women

ObjectiveThyroid dysfunction (overt and subclinical) has been consistently linked to pregnancy adversity and abnormal fetal growth and development. Mood disorders such as anxiety, depression, and obsessive-compulsive disorder (OCD) are frequently diagnosed during pregnancy and at postpartum, and emerging evidence suggests association with impaired offspring neurodevelopment and growth. This study aimed to examine potential associations between thyroid function and mood symptoms during pregnancy and postpartum.DesignThis is a prospective study measuring thyroid hormones and assessing mood symptoms by employing specific questionnaires in the same cohort of 93 healthy pregnant women at the 24th (2nd trimester) and 36th (3rd trimester) gestational weeks and at the 1st postpartum week.MethodsSerum thyroid hormones, TSH, anti-TPO, and anti-Tg antibodies were measured at the 24th (2nd trimester) and 36th (3rd trimester) gestational weeks and at the 1st postpartum week. Specific validated questionnaires were employed at the same time-points to assess separately symptoms of anxiety [Generalized Anxiety Disorder Inventory (GADI), Penn State Worry Questionnaire (PSWQ), STAI-State Anxiety inventory (STAI-S), STAI-Trait Anxiety Inventory (STAI-T)], depression [Edinburgh Postnatal Depression Scale (EPDS), Stein’s Blues Scale (BLUES), Beck Depression Inventory (BDI)], and obsessive compulsive disorder (OCD) [Yale-Brown Obsessive Compulsive scale (Y-BOCS)].ResultsAt the 2nd trimester, GADI score correlated negatively with FT3 (p < 0.010, r = −0.545) and positively with TSH (p < 0.050, r = 0.837) concentrations; GADI, PSWQ, EPDS and Y-BOCS scores correlated negatively with FT4 concentrations (p < 0.010, r = −0.768; p < 0.010, r = −0.384; p < 0.050, r = −0.364; p < 0.010, r = −0.544, respectively). At the 3rd trimester, BLUES score correlated positively with rT3 concentrations (p = 0.00, r = 0.89); GADI, EPDS, and Y-BOCS scores correlated negatively with FT4 concentrations (p = 0.001, r = − 0.468; p = 0.036, r = −0.39; p = 0.001, r = −0.625, respectively); GADI, STAI-S, and Y-BOCS scores correlated positively with TSH concentrations (p = 0.015, r = 0.435; p = 0.024, r = 0.409 p = 0.041, r = 0.389, respectively). At postpartum, PSWQ, STAI-T, EPDS, and BDI scores correlated positively with rT3 concentrations (p = 0.024, r = 0.478; p = 0.014, r = 0.527; p = 0.046, r = 0.44; p = 0.021, r = 0.556, respectively, Y-BOCS score correlated positively with TSH (p = 0.045, r = 0.43), and BLUES score correlated positively with anti-TPO antibody concentrations (p = 0.070, r = 0.586).ConclusionThe reported findings demonstrate positive associations between low-normal thyroid function at the 2nd and 3rd trimesters of pregnancy and postpartum with anxiety, depression, and OCD scores.

Severity of Subjective Cognitive Complaints and Worries in Older Adults Are Associated With Cerebral Amyloid-β Load

Subjective cognitive decline (SCD) is considered an early risk stage for dementia due to Alzheimer's disease (AD) and the development of pathological brain changes, such as the aggregation of amyloid-beta (amyloid-β) plaques. This study evaluates the association between specific features of SCD and cerebral amyloid-β load measured by positron emission tomography (PET) with 18F-florbetaben in 40 cognitively normal older individuals. Global amyloid-β, as well as regional amyloid-β load for the frontal, temporal, parietal, and cingulate cortex, was quantified. Specific features of SCD, such as subjective cognitive complaints and worry, were assessed using the 39-item Everyday Cognition Scales and the 16-item Penn State Worry Questionnaire. Spearman's rank partial correlation analyses, adjusted for age and apolipoprotein E ε4 status, were conducted to test the associations between specific features of SCD and cerebral amyloid-β load. The severity of subjective cognitive complaints in everyday memory and organization was positively correlated with amyloid-β load in the frontal cortex. In addition, the severity of subjective cognitive complaints in everyday planning was positively correlated with amyloid-β load in the parietal cortex. Higher levels of worry were associated with higher amyloid-β load in the frontal cortex. After correction of the PET data for partial volume effects, these associations were reduced to trend level. In conclusion, the severity of subjective cognitive complaints and the level of trait worry were positively associated with cortical amyloid-β burden, particularly in the frontal and parietal cortex. Further studies are required to elucidate the direction of these associations in order to develop strategies to prevent amyloid deposition and cognitive decline.