direct applicability
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2021 ◽  
Vol 9 (4) ◽  
pp. 1-34
Author(s):  
Folke J. Glastra ◽  
Cornelis J. De Brabander

In this study on motivations concerning professional development (PD) we interviewed 95 primary school teachers in the Netherlands. We coded these data using the Unified Model of Task-specific Motivation (de Brabander & Martens, 2014) in different decision contexts concerning who decides about teacher participation in PD: school board, teacher teams, or individual teachers. We analysed the valences that teachers associated with PD activities, their experiences of autonomy, and whether and how these variables were affected by decision context and teacher age. Results show that decision contexts relate differently to valences and autonomy experiences. Positive autonomy and positive valences increased going from schoolboard to team to individual decision contexts. Whereas the literature on effective teacher PD stresses the importance of PD design features, our study is the first to empirically demonstrate the crucial influence of decision contexts. Among older teachers, teaching experience informed the selection of PD content to transfer to their classrooms. Younger teachers tended to first explore whether PD worked in their classrooms before deciding about adoption. Direct applicability emerged as a dominant criterion for evaluating PD. Decision context and autonomy regarding PD programmes play important roles in ensuring applicability. Our research revealed that the dominance of the direct applicability criterion was not motivated by student benefits alone. It was also based in an attitude of efficiency among primary teachers, reflecting growing work pressures and a general prioritisation of classroom teaching above all other tasks, including PD.



2021 ◽  
Vol 13 (17) ◽  
pp. 3355
Author(s):  
Dani Varghese ◽  
Mirjana Radulović ◽  
Stefanija Stojković ◽  
Vladimir Crnojević

This paper systematically reviews the potential of the Sentinel-2 (A and B) in assessing drought. Research findings, including the IPCC reports, highlighted the increasing trend in drought over the decades and the need for a better understanding and assessment of this phenomenon. Continuous monitoring of the Earth’s surface is an efficient method for predicting and identifying the early warnings of drought, which enables us to prepare and plan the mitigation procedures. Considering the spatial, temporal, and spectral characteristics, the freely available Sentinel-2 data products are a promising option in this area of research, compared to Landsat and MODIS. This paper evaluates the recent developments in this field induced by the launch of Sentinel-2, as well as the comparison with other existing data products. The objective of this paper is to evaluate the potential of Sentinel-2 in assessing drought through vegetation characteristics, soil moisture, evapotranspiration, surface water including wetland, and land use and land cover analysis. Furthermore, this review also addresses and compares various data fusion methods and downscaling methods applied to Sentinel-2 for retrieving the major bio-geophysical variables used in the analysis of drought. Additionally, the limitations of Sentinel-2 in its direct applicability to drought studies are also evaluated.



2021 ◽  
pp. 44-46
Author(s):  
Xiaowei Sun

This chapter focuses on administrative procedure and judicial review in China. Despite its willingness to adapt to the rules of the global market, China does not accept the direct applicability of international standards in administrative litigation. Judicial review of administration is based on a set of legislative texts and judicial interpretations by the Supreme People's Court. Among these texts, the Administrative Litigation Law regulates the judicial review of administrative acts. There are two lists in its chapter concerning the scope of judicial review: one includes the administrative acts that are open to judicial review, another the acts that are not reviewable. In any case, it is up to the courts to examine the following two combinations of criteria: the degree of the seriousness of the infringement with the definition of the state interest and that of the public interest; and the degree of procedural breach with the definition of the real impact on the rights of the plaintiff. According to Article 76 of the ALL, in the case of annulment and/or declaration of unlawfulness of an administrative act, a court may order the administration to take measures to compensate the damage inflicted on the plaintiff.



2021 ◽  
pp. 166-207
Author(s):  
Nigel Foster

This chapter brings together a number of related issues that are indirectly linked to the preliminary ruling procedure under Art 267 of the Treaty on the Functioning of the EU (TFEU)—the vehicle by which the leading principles and remedies in EU law were developed by the Court of Justice; in particular, the means by which EU law could be enforced by individuals via the national courts, rather than by the Commission, or other institutions, or member states in direct actions before the CJEU. The discussions cover Art 267 TFEU; direct applicability and direct effects; state liability; and national procedural law and the system of remedies.



2021 ◽  
Author(s):  
Georgios Ioannides ◽  
Ioannis Kourouklides ◽  
Alessandro Astolfi

Abstract Methods on modelling the human brain as a Complex System have increased remarkably in the literature as researchers seek to understand the underlying foundations behind cognition, behaviour, and perception. Computational methods, especially Graph Theory-based methods, have recently contributed significantly in understanding wiring connectivity of the brain, modelling it as a set of nodes connected by edges. Therefore, the brain's spatiotemporal dynamics can be holistically studied by considering a network, which consists of many neurons, represented by nodes. Various models have been proposed for modelling such neurons. A recently proposed method in training such networks, called full-Force, produces networks that perform tasks with fewer neurons and greater noise robustness than previous least-squares approaches (i.e. FORCE method). In this paper, the first direct applicability of a variant of the full-Force method to biologically-motivated Spiking RNNs (SRNNs) is demonstrated. The SRNN is a graph consisting of modules. Each module is modelled as a Small-World Network (SWN), which is a specific type of a biologically-plausible graph. So, the first direct applicability of a variant of the full-Force method to modular SWNs is demonstrated, evaluated through regression and information theoretic metrics. For the first time, the aforementioned method is applied to spiking neuron models and trained on various real-life Electroencephalography (EEG) signals. To the best of the authors' knowledge, all the contributions of this paper are novel. Results show that trained SRNNs match EEG signals almost perfectly, while network dynamics can mimic the target dynamics. This demonstrates that the holistic setup of the network model and the neuron model which are both more biologically plausible than previous work, can be tuned into real biological signal dynamics.



Pharmaceutics ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 1153
Author(s):  
Juliana Cotabarren ◽  
Brenda Ozón ◽  
Santiago Claver ◽  
Javier Garcia-Pardo ◽  
Walter David Obregón

Geoffroea decorticans is a xerophilous deciduous tree present in most arid forests of southern South America, which is commonly used in traditional medicine. The seeds of this tree have been previously investigated for their singular chemical composition, but their protein content has been poorly investigated. Herein, we report the isolation, purification, and characterization of a set of thermostable peptides derived from Geoffroea decorticans seeds (GdAPs) with strong antioxidant and anticoagulant activities. The most potent antioxidant peptides showed a half maximal inhibitory concentration (IC50) of 35.5 ± 0.3 µg/mL determined by 1,1-diphenyl-2-picrylhydrazyl (DPPH). They also caused a dose-dependent prolongation of the aPTT clotting time with an IC50 value of ~82 µg/mL. Interestingly, MALDI-TOF/MS analysis showed the presence of three major peptides with low molecular weights of 2257.199 Da, 2717.165 Da, and 5422.002 Da. The derived amino-acid sequence of GdAPs revealed their unique structural features, exhibiting homology with various proteins present in the genome of Arachis hypogaea. All in all, our data suggest a direct applicability of GdAPs for pharmaceutical purposes.



2021 ◽  
Author(s):  
Binzheng Zhang

<p>The classic Dungey cycle plays an essential role in understanding the dynamics of the terrestrial magnetosphere. However, its direct applicability to planetary magnetospheres such as Jupiter is limited, especially when the planetary rotation is much faster than the Earth. We use a series of numerical experiments to show the transition of the terrestrial magnetosphere from a classic Dungey cycle, convection-dominated system to rotation-dominated configurations. The numerical experiments use the Earth's magnetosphere-ionosphere system as a testbed, with modified rotation speed to increase the influence of planetary rotation over solar wind driving, characterized by the ratio between the solar wind merging potential and the polar cap rotation potential. Results show that when the rotation potential of the polar magnetosphere becomes comparable to the merging potential of the solar wind, the classic Dungey cycle is modified by azimuthal transport of magnetic flux, resulting in a more closed polar magnetosphere with a crescent-shaped open flux region in the ionosphere. These numerical experiments provide a theoretical framework for understanding the fundamentals of magnetospheric physics, which is potentially applicable to the Saturn, Jupiter, and exo-planetary systems.</p>



Author(s):  
Hanns Ullrich

AbstractPrivate enforcement of the European Union’s rules on competition (Arts. 101, 102 TFEU) has become prominent as a counterpart to their public enforcement. Mostly, it is identified with tort actions brought under EU-harmonized national law by individuals claiming compensation for the harm suffered from anticompetitive agreements or practices. However, claims for compensation represent imperfect sanctions for the infringement of the competition rules because they are brought only once the damage is done and at a time when the conditions of competition may have changed. Typically also, such private actions are no equivalent or complement to administrative enforcement, but are largely dependent on it (follow-on actions). In addition, bringing them is attractive only if the damage suffered is considerable, sufficient evidence available, and the defendant solvent enough. Therefore, this paper revisits the first line of private enforcement, which is enforcing the nullity of anticompetitive agreements as provided for directly by primary Union law in Art. 101(2) TFEU. Nullity was a much-discussed issue under the authorization regime of Reg. 17/62, the first regulation implementing the enforcement of the competition rules, but has become somewhat neglected as a sanction since Reg. 1/2003 changed the enforcement system. Yet, it is precisely under the regime of immediate and direct applicability of both Arts. 101(1) and 101(3) TFEU, which Reg. 1/2003 reestablished, that the potential of nullity as a sanction of anticompetitive agreements could be fully activated. Such active use of invalidity challenges may lead to redefining the interface between EU law and national contract law, which is the line of severability of the innocent parts of a restrictive agreement from its anti-competitive parts. It should also result in reassessing the legal fate of follow-on transactions concluded by a party to an anticompetitive agreement with third parties, and it should bring abusive contracts within the realm of the nullity sanction that dominant firms impose on third parties. The guiding principle for such general reappraisal of the nullity sanction must be to bring its purpose fully to bear, which is to facilitate exit from anticompetitive agreements or from (abusive) contract clauses with a view to reopening competition and/or to allow the renegotiating of a transaction in terms of undistorted competition. This may mean that only the party whose freedom of competition is restricted may claim nullity.



Nanomaterials ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 1039
Author(s):  
Alina Adriana Minea ◽  
S. M. Sohel Murshed

Ionic liquids are a new and challenging class of fluids with great and tunable properties, having the capability of an extensive area of real-life applications, from chemistry, biology, medicine to heat transfer. These fluids are often considered as green solvents. Several properties of these fluids can be enhanced by adding nanoparticles following the idea of nanofluids. These ionic liquids-based nanocolloids are also termed in the literature as ionanofluids or nanoparticles-enhanced ionic liquids. This review summarizes the findings in both areas of ionic liquids and ionic liquids nanocolloids (i.e., ionic liquids with nanoparticles in suspension) with direct applicability in convective heat transfer applications. The review presents in a unified manner the progress and prospects of ionic liquids and their nanocolloids from preparation, thermophysical properties and equally experimental and numerical works. As the heat transfer enhancement requires innovative fluids, this new class of ionic liquids-based nanocolloids is certainly a viable option, despite the noticed drawbacks. Nevertheless, experimental studies are very limited, and thus, extensive experiments are needed to elucidate ionic liquids interaction with nanoparticles, as well as their behavior in convective heat transfer.



2021 ◽  
Author(s):  
Nino Läubli ◽  
Michael Gerlt ◽  
Alexander Wüthrich ◽  
Renard Lewis ◽  
Naveen Shamsudhin ◽  
...  

Acoustically excited microstructures have demonstrated significant potential for small scale biomedical applications by overcoming major microfluidic limitations. Recently, the application of oscillating microbubbles has demonstrated their superiority over acoustically excited solid structures due to their enhanced acoustic streaming at low input power. However, their limited temporal stability hinders their direct applicability for industrial or clinical purposes. Here, we introduce the embedded microbubble, a novel acoustofluidic design based on the combination of solid structures (polydimethylsiloxane) and microbubbles (air-filled cavity) to combine benefits of both approaches while minimizing their drawbacks. We investigate the influence of various design parameters and geometrical features through numerical simulations and experimentally evaluate their manipulation capabilities. Finally, we demonstrate the capabilities of our design for microfluidic applications by investigating its mixing performance as well as through the controlled rotational manipulation of individual HeLa cells.<br>



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