Printed Nanocarbon Heaters for Stretchable Sport and Leisure Garments

The ability to maintain body temperature has been shown to bring about improvements in sporting performance. However, current solutions are limited with regards to flexibility, heating uniformity and robustness. An innovative screen-printed Nanocarbon heater is demonstrated which is robust to bending, folding, tensile extensions of up to 20% and machine washing. This combination of ink and substrate enables the heated garments to safely flex without impeding the wearer. It is capable of producing uniform heating over a 15 × 4 cm area using a conductive ink based on a blend of Graphite Nanoplatelets and Carbon Black. This can be attributed to the low roughness of the conductive carbon coating, the uniform distribution and good interconnection of the carbon particles. The heaters have a low thermal inertia, producing a rapid temperature response at low voltages, reaching equilibrium temperatures within 120 s of being switched on. The heaters reached the 40 °C required for wearable heating applications within 20 s at 12 Volts. Screen printing was demonstrated to be an effective method of controlling the printed layer thickness with good interlayer adhesion and contact for multiple printed layers. This can be used to regulate their electrical properties and hence adjust the heater performance.

The Genetics of Thermoregulation in Pigs: A Review

Heat stress (HS) affects pig performance, health and welfare, resulting in a financial burden to the pig industry. Pigs have a limited number of functional sweat glands and their thermoregulatory mechanisms used to maintain body temperature, are challenged by HS to maintain body temperature. The genetic selection of genotypes tolerant to HS is a promising long-term (adaptation) option that could be combined with other measures at the production system level. This review summarizes the current knowledge on the genetics of thermoregulation in pigs. It also discusses the different phenotypes that can be used in genetic studies, as well as the variability in thermoregulation between pig breeds and the inheritance of traits related to thermoregulation. This review also considers on-going challenges to face for improving heat tolerance in pigs.

THE EFFECT OF KANGAROO METHOD ON IMPROVEMENT BODY WEIGHT ON LOW BIRTH WEIGHT

Background: In Indonesia the Neonatal mortality rate was 15 infants per 1000 births and in Surabaya in 2018 LBW deaths were 50 per 1000 live births, while in Haji General Hospital the LBW deaths were 12 babies in 1 year. Kangaroo care was the most effective way to meet the basic needs of LBW. Babies with 1500-2500 grams body weight either due to prematurity or small pregnancy period will lose weight ranging from 10-15% in 7 days of life. To overcome the problem Kangaroo care method4 component aims to promote weight loss, maintain body temperature remains stable and facilitate breastfeeding Methods: The method of this study was observational analytic with the design of the study cohort. Total sample of 40 LBW with sampling techniques using Sequential Sampling in the period August-October period 2019. Variabel was free kangaroo care method given 1-2 times a day with a duration of more than 120 minutes. The dependent variable was increased in body weight carried out 3x the measurement. Results: The results of the study using paired T test showed an increase in body weight, namely 1) the first measurement of 31.82 grams for 3 days with p = 0.037, 2) the second measurement increased by 227.15 for 7 days, with p = 0,000, 3) the third measurement was 258.97 with p = 0,000. The conclusion: of the studied, that there were a significant difference between the kangaroo method treatments for weight gain in LBW in the NICU Room Haji Hospital Surabaya

Dietary Exposure to Low Levels of Crude Oil Affects Physiological and Morphological Phenotype in Adults and Their Eggs and Hatchlings of the King Quail (Coturnix chinensis)

Despite the current knowledge of the devastating effects of external exposure to crude oil on animal mortality, the study of developmental, transgenerational effects of such exposure has received little attention. We used the king quail as an animal model to determine if chronic dietary exposure to crude oil in a parental population would affect morpho-physiological phenotypic variables in their immediate offspring generation. Adult quail were separated into three groups: (1) Control, and two experimental groups dietarily exposed for at least 3 weeks to (2) Low (800 PAH ng/g food), or (3) High (2,400 PAH ng/g food) levels of crude oil. To determine the parental influence on their offspring, we measured metabolic and respiratory physiology in exposed parents and in their non-exposed eggs and hatchlings. Body mass and numerous metabolic (e.g., O2 consumption, CO2 production) and respiratory (e.g., ventilation frequency and volume) variables did not vary between control and oil exposed parental groups. In contrast, blood PO2, PCO2, and SO2 varied among parental groups. Notably, water loss though the eggshell was increased in eggs from High oil level exposed parents. Respiratory variables of hatchlings did not vary between populations, but hatchlings obtained from High oil-exposed parents exhibited lower capacities to maintain body temperature while exposed to a cooling protocol in comparison to hatchlings from Low- and Control-derived parents. The present study demonstrates that parental exposure to crude oil via diet impacts some aspects of physiological performance of the subsequent first (F1) generation.

Temperatura corporal y temperatura de calentamiento en el cuidado de pacientes grandes quemados

Objetivos: El objetivo es describir los métodos de calentamiento y su aplicación para el mantenimiento de la temperatura corporal en el paciente gran quemado.Metodología: Revisión bibliográfica realizada entre septiembre de 2019 y febrero de 2020 acerca de la termorregulación y calentamiento del paciente quemado en las bases de datos CINAHL, CUIDEN, PUBMED, MEDES y WOS en español e inglés, de los últimos 10 años, de los cuales fueron analizados 24 documentos.Resultados: La respuesta hipermetabólica y la reprogramación hipotalámica provocan un aumento de la temperatura basal en los pacientes quemados, entre 37 y 38,5ºC sin origen infeccioso. Para disminuir el gasto energético en reposo y la repuesta hipermetabólica se puede aplicar una temperatura ambiental elevada, como calentamiento externo pasivo, entre 28 y 32ºC. Discusión: Existen otros métodos de calentamiento externo activo que pueden conseguir el mismo objetivo como las mantas de aire convectivo, placas térmicas o sistemas de superficie.Conclusión: Debe revisarse la recomendación de calentamiento mediante temperatura ambiental elevada, que crea ambientes hostiles para los trabajadores y los pacientes, a través del estudio de la inclusión de métodos de calentamiento externo activo. Objectives: To describe the heating methods and their application to maintain body temperature in majors burn patients.Methodology: Bibliographic review carried out between September 2019 and February 2020 about the thermoregulation and heating of the burn patient in the CINHAL, CUIDEN, PUBMED, MEDES and WOS databases in Spanish and English, documents from the last 10 years, from which 26 were analyzed.Results: Hypermetabolic response and hypothalamic reprogramming cause an increase in basal temperature in burn patients between 37 and 38.5ºC without infectious origin. To decrease the energy expenditure at rest and the hypermetabolic response, it is possible to act through a high ambient temperature between 28 and 32ºC as passive external heating. Discussion: Other external heating methods can achieve this goal such as convective air blankets, heating plates, or surface systems.Conclusions: The recommendation of warming by means of high ambient temperature, which creates hostile environments for workers and patients, should be reviewed through the study of the inclusion of active external warming methods.

Contrasting recruitment of skin-associated adipose depots during cold challenge of mouse and human

Mammalian skin impacts metabolic efficiency system-wide, controlling the rate of heat loss and consequent heat production. Here we compare the unique fat depots associated with mouse and human skin, to determine whether they have corresponding function and regulation. For human, we distinguish skin-associated fat (SAF) as the body-wide depot and characterize it separately from the subcutaneous fat pads characteristic of abdomen and upper limbs. We show that the thickness of SAF is not related to general adiposity; it is much thicker (1.6-fold) in women than men, and highly subject-specific. We used molecular and cellular assays of β-adrenergic induced lipolysis and found that dermal white adipose tissue (dWAT) in mice is resistant to lipolysis; in contrast, the body-wide human SAF depot becomes lipolytic, generating heat in response to β-adrenergic stimulation. In mice challenged to make more heat to maintain body temperature (either environmentally or genetically), the thickness of dWAT increases, whereas β-adrenergic stimulation reduces the size of human skin-associated adipocytes. We summarize the regulation of the skin-associated adipocytes by age, sex, and adiposity, for both species, and conclude that overall, a combination of subcutaneous and dermal adipose tissues in mouse contributes the same way to maintaining body temperature as human SAF.

The Role of Leptin Levels in Adaptation to Cold Climates

Currently, adipose tissue is considered an endocrine organ that produces hormone-active substances, including leptin, which can play a key role in thermoregulation processes. Therefore, we performed a meta-analysis to investigate the influence of the climatic environment on leptin levels. A systematic literature search in the databases was carried out on 10 January 2020. Finally, 22 eligible articles were included in the current meta-analysis and a total of 13,320 participants were covered in the final analysis. It was shown that males of the “North” subgroup demonstrated significantly higher levels of leptin (10.02 ng/mL; CI: 7.92–12.13) than males of the “South” subgroup (4.9 ng/mL; CI: 3.71–6.25) (p = 0.0001). On the contrary, in the female group, a similar pattern was not detected (p = 0.91). Apparently, in order to maintain body temperature, higher leptin levels are required. The results of the study indicate that such effects are most pronounced in males and to a smaller extent in females, apparently due to a relatively high initial concentration of leptin in females. The correlation between leptin levels and climatic environment data support the hypothesis of leptin-mediated thermoregulation as an adaptive mechanism to cold climates.

Glucose Injections at Birth, Warmth and Placing at a Nurse Sow Improve the Growth of IUGR Piglets

Intrauterine growth-restricted piglets (IUGR) have a lower rectal temperature, whole-blood glucose, and lower glycogen storages at birth than normal piglets, giving them less energy to maintain body temperature and compete at the udder. The present paper investigated the effects of giving an energy supplementation three times after birth on rectal temperature, glucose levels, and growth until weaning in an on-farm trial. Eighty-eight newborn piglets were classified as IUGR (based on head morphology), placed under a heating lamp for one hour and allocated to one of four treatments—warmed water (WATER), glucose injection (GLUC), colostrum bolus (COLOS; porcine colostrum), and colostrum bolus and glucose injection (GLUC + COLOS)—before being placed at a nursing sow. Weight differences were found at day 21, with GLUC and GLUC + COLOS groups being the heaviest. Piglets in GLUC + COLOS had higher glucose levels at t = 3, 6, and 9 h compared to the other treatments (p = 0.027), but from t = 24 h and onwards, no difference was observed. For rectal temperature, no differences were observed. Collectively, these findings suggest that glucose injections at birth (i.e., as an energy source), one hour’s exposure to warmth and the placement of piglets with a nurse sow to reduce competition, enhance the growth of IUGR piglets.

Glucagon, GLP-1 and Thermogenesis

Brown adipose tissue (BAT) thermogenesis is a conserved mechanism to maintain body temperature in mammals. However, since BAT contribution to energy expenditure can represent a relevant modulator of metabolic homeostasis, many studies have focused on the nervous system and endocrine factors that control the activity of this tissue. There is long-established evidence that the counter-regulatory hormone glucagon negatively influences energy balance, enhances satiety, and increases energy expenditure. Despite compelling evidence showing that glucagon has direct action on BAT thermogenesis, recent findings are questioning this conventional attribute of glucagon action. Glucagon like peptide-1 (GLP-1) is an incretin secreted by the intestinal tract which strongly decreases feeding, and, furthermore, improves metabolic parameters associated with obesity and diabetes. Therefore, GLP-1 receptors (GLP-1-R) have emerged as a promising target in the treatment of metabolic disorders. In this short review, we will summarize the latest evidence in this regard, as well as the current therapeutic glucagon- and GLP-1-based approaches to treating obesity.