reasonable assumption
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2022 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Ian Timothy Riley

PurposeWith the current dynamics of scientific publishing increasingly driven by citation metrics, it is quite possible this will lead to the loss of some lower-ranked journals as they will be undervalued by authors, research institutions and research funders. This has been specifically predicted for natural science journals, but the efforts of editors of such journals to improve reputation have not been quantitatively assessed. This research aimed to fill this knowledge gap and assess the potential vulnerability of lower-ranked botany journals.Design/methodology/approachChanges in article citation rates since 2009 for 21 lower-ranked general botany journals were examined by least squares linear regression and factors potentially predictive of higher citation potential by principal component analysis. The findings were then examined in a case study of the publishing that followed the celebrated discovery of a living-fossil plant (Wollemia nobilis) in the mid-1990s.FindingsArticle citation rates steadily declined across most of these 21 journals over the period, and if submissions had been favoured (directly or indirectly) for citation potential, this appears to have been an ineffective, perhaps even a flawed, endeavour. Analysis of quantifiable article attributes across a subset of these journals revealed inconsistent relationships with no predictive value for citation potential. The case study clearly highlighted some processes contributing to declining citation rates and the value of botanical reporting well beyond that indicated by citation metrics.Research limitations/implicationsIt is not possible to know how important prediction of citation potential (directly or indirectly) is when journal editors accept papers for review or publication (such information is not made public, and this might not be a formalised process), so this study is only based what is considered (by the author) to be a reasonable assumption that all journals aim to improve their reputation and use citation metrics as one determinant of this.Social implicationsUnless we give value to lower-ranked regional botany journals in other ways than citations, the current trends in citation rates could lead to the diminution, even loss, of their valuable contribution biodiversity conservation.Originality/valueAlthough concerns have been expressed about the long-term viability of natural history journals, this is the first research to examine this quantitatively using citation metrics.


2022 ◽  
pp. 78-101
Author(s):  
Amy L. Rathbone ◽  
Duncan Cross ◽  
Julie Prescott

At the start of 2020, the World Health Organisation (WHO) declared COVID-19 as a global pandemic. Pregnant women were deemed a vulnerable group globally and advised to shield. Due to social distancing and the changes in maternity services, it was a reasonable assumption that pregnant women would turn to the online platform for advice and guidance. Using reflexive thematic analysis, this chapter explored the effect of social media, support groups, and app usage on pregnant women during the outbreak. Results evidenced that pregnant women utilised social media, support groups, and apps for information and support. Positive aspects were maintaining social connections whilst adhering to social distancing guidelines, access to support groups and people in similar situations, and ease of access to information. Negative aspects were excessive amounts of and overwhelming information, misinformation, judgement from others, and increased anxiety. Apps were deemed positive for general pregnancy but lacked COVID-19-related information.


Complexity ◽  
2021 ◽  
Vol 2021 ◽  
pp. 1-15
Author(s):  
Kejian Tang ◽  
Shaohui Zhan ◽  
Tao Zhan ◽  
Hui Zhu ◽  
Qian Zeng ◽  
...  

While promoting a business or activity in geo-social networks, the geographical distance between its location and users is critical. Therefore, the problem of Distance-Aware Influence Maximization (DAIM) has been investigated recently. The efficiency of DAIM heavily relies on the sample location selection. Specifically, the online seeding performance is sensitive to the distance between the promoted location and its nearest sample location, and the offline precomputation performance is sensitive to the number of sample locations. However, there is no work to fully study the problem of sample location selection for DAIM in geo-social networks. To do this, we first formalize the problem under a reasonable assumption that a promoted location always adheres to the distribution of users (query zone). Then, we propose two efficient location sampling approaches based on facility location analysis, which is one of the most well-studied areas of operations research, and these two approaches are denoted by Facility Location based Sampling (FLS) and Conditional Facility Location Based Sampling (CFLS), respectively. FLS conducts one-time sample location selection, and CFLS extends the one-time sample location selection to a continuous process, so that an online advertising service can be started immediately without sampling a lot of locations. Our experimental results on two real datasets demonstrate the effectiveness and efficiency of the proposed methods. Specifically, both FLS and CFLS can achieve better performance than the existing sampling methods for the DAIM problem, and CFLS can initialize the online advertising service in a matter of seconds and achieve better objective distance than FLS after sampling a large number of sample locations.


2021 ◽  
Vol 3 ◽  
Author(s):  
Raphael Payet-Burin ◽  
Mikkel Kromman ◽  
Silvio J. Pereira-Cardenal ◽  
Kenneth M. Strzepek ◽  
Peter Bauer-Gottwein

Perfect foresight hydroeconomic optimization models are tools to evaluate impacts of water infrastructure investments and policies considering complex system interlinkages. However, when assuming perfect foresight, optimal management decisions are found assuming perfect knowledge of climate and runoff, which might bias the economic evaluation of investments and policies. We investigate the impacts of assuming perfect foresight by using Model Predictive Control (MPC) as an alternative. We apply MPC in WHAT-IF, a hydroeconomic optimization model, for two study cases: a synthetic setup inspired by the Nile River, and a large-scale investment problem on the Zambezi River Basin considering the water–energy–food nexus. We validate the MPC framework against Stochastic Dynamic Programming and observe more realistic modeled reservoir operation compared to perfect foresight, especially regarding anticipation of spills and droughts. We find that the impact of perfect foresight on total system benefits remains small (<2%). However, when evaluating investments and policies using with-without analysis, perfect foresight is found to overestimate or underestimate values of investments by more than 20% in some scenarios. As the importance of different effects varies between scenarios, it is difficult to find general, case-independent guidelines predicting whether perfect foresight is a reasonable assumption. However, we find that the uncertainty linked to climate change in our study cases has more significant impacts than the assumption of perfect foresight. Hence, we recommend MPC to perform the economic evaluation of investments and policies, however, under high uncertainty of future climate, increased computational costs of MPC must be traded off against computational costs of exhaustive scenario exploration.


2021 ◽  
Vol 109 (1) ◽  
Author(s):  
Mateusz Glenszczyk ◽  
David Outomuro ◽  
Matjaž Gregorič ◽  
Simona Kralj-Fišer ◽  
Jutta M. Schneider ◽  
...  

AbstractExamining the role of color in mate choice without testing what colors the study animal is capable of seeing can lead to ill-posed hypotheses and erroneous conclusions. Here, we test the seemingly reasonable assumption that the sexually dimorphic red coloration of the male jumping spider Saitis barbipes is distinguishable, by females, from adjacent black color patches. Using microspectrophotometry, we find clear evidence for photoreceptor classes with maximal sensitivity in the UV (359 nm) and green (526 nm), inconclusive evidence for a photoreceptor maximally sensitive in the blue (451 nm), and no evidence for a red photoreceptor. No colored filters within the lens or retina could be found to shift green sensitivity to red. To quantify and visualize whether females may nevertheless be capable of discriminating red from black color patches, we take multispectral images of males and calculate photoreceptor excitations and color contrasts between color patches. Red patches would be, at best, barely discriminable from black, and not discriminable from a low-luminance green. Some color patches that appear achromatic to human eyes, such as beige and white, strongly absorb UV wavelengths and would appear as brighter “spider-greens” to S. barbipes than the red color patches. Unexpectedly, we discover an iridescent UV patch that contrasts strongly with the UV-absorbing surfaces dominating the rest of the spider. We propose that red and black coloration may serve identical purposes in sexual signaling, functioning to generate strong achromatic contrast with the visual background. The potential functional significance of red coloration outside of sexual signaling is discussed.


Life ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 1333
Author(s):  
Isabella Csadek ◽  
Peter Paulsen ◽  
Pia Weidinger ◽  
Kathrine H. Bak ◽  
Susanne Bauer ◽  
...  

Viral contamination of edible bivalves is a major food safety issue. We studied the virucidal effect of a cold atmospheric plasma (CAP) source on two virologically different surrogate viruses [a double-stranded DNA virus (Equid alphaherpesvirus 1, EHV-1), and a single-stranded RNA virus (Bovine coronavirus, BCoV)] suspended in Dulbecco’s Modified Eagle’s Medium (DMEM). A 15 min exposure effectuated a statistically significant immediate reduction in intact BCoV viruses by 2.8 (ozone-dominated plasma, “low power”) or 2.3 log cycles (nitrate-dominated, “high power”) of the initial viral load. The immediate effect of CAP on EHV-1 was less pronounced, with “low power” CAP yielding a 1.4 and “high power” a 1.0 log reduction. We observed a decline in glucose contents in DMEM, which was most probably caused by a Maillard reaction with the amino acids in DMEM. With respect to the application of the virucidal CAP treatment in oyster production, we investigated whether salt water could be sanitized. CAP treatment entailed a significant decline in pH, below the limits acceptable for holding oysters. In oyster slurry (a surrogate for live oysters), CAP exposure resulted in an increase in total nitrogen, and, to a lower extent, in nitrate and nitrite; this was most probably caused by absorption of nitrate from the plasma gas cloud. We could not observe a change in colour, indicative for binding of NOx to haemocyanin, although this would be a reasonable assumption. Further studies are necessary to explore in which form this additional nitrogen is deposited in oyster flesh.


2021 ◽  
Vol 12 ◽  
Author(s):  
Graham A. Mackay ◽  
Nithya A. Fernandopulle ◽  
Jie Ding ◽  
Jeremy McComish ◽  
Paul F. Soeding

Acute anaphylaxis to small molecule drugs is largely considered to be antibody-mediated with immunogloblin E (IgE) and mast cell activation being key. More recently, a role for drug-reactive immunoglobulin G (IgG) with neutrophil activation has also been suggested, at least in reactions to neuromuscular blocking agents (NMBAs). However, the mast cell receptor MRGPRX2 has also been highlighted as a possible triggering mechanism in acute anaphylaxis to many clinically used drugs. Significantly, MRGPRX2 activation is not dependent upon the presence of drug-recognising antibody. Given the reasonable assumption that MRGPRX2 is expressed in all individuals, the corollary of this is that in theory, anybody could respond detrimentally to triggering drugs (recently suggested to be around 20% of a drug-like compound library). But this clearly is not the case, as the incidence of acute drug-induced anaphylaxis is very low. In this mini-review we consider antibody-dependent and -independent mechanisms of mast cell activation by small molecule drugs with a focus on the MRGPRX2 pathway. Moreover, as a juxtaposition to these adverse drug actions, we consider how increased understanding of the role of MRGPRX2 in anaphylaxis is important for future drug development and can complement exploration of this receptor as a drug target in broader clinical settings.


2021 ◽  
Vol 2081 (1) ◽  
pp. 012001
Author(s):  
Aroonkumar Beesham

Abstract Since the discovery of the late-time acceleration of the universe, researchers are still trying to fnd an explanation for it. This is regarded as the most important unsolved problem in cosmology today. The most favoured explanation is dark energy, an unknown or exotic form of matter with negative pressure. One may argue that particle physics may provide the answer in time. Currently, the LambdaCDM model is regarded as the best model. Although this model is reasonably successful and widely accepted, there is growing interest in looking at alternatives. Some of the reasons for this are the fne-tuning, coincidence, infationary paradigm and cosmological constant problems, and whether general relativity is valid on large scales. One focus in trying to understand dark energy is to assume some form of the scale, Hubble or deceleration parameter (or some other reasonable assumption), and then to see how well the model fts in with current observations. This approach is broadly called reconstruction. In this talk, we focus on the deceleration parameter. We provide a brief review of the various forms of the deceleration parameter that have been employed in the past in cosmology, and then focus on some particular forms of interest which have drawn some attention. We note that it is most worthwhile to study alternative dark energy and dark gravity models in order to fully understand the entire space of possibilities.


2021 ◽  
Vol 13 (19) ◽  
pp. 10842
Author(s):  
Katarína Draganová ◽  
Karol Semrád ◽  
Monika Blišťanová ◽  
Tomáš Musil ◽  
Rastislav Jurč

The coronavirus disease has influenced almost all of our everyday activities. Traveling and transportation have been influenced significantly and there is no doubt that air transportation has been restricted and therefore reduced considerably. It is predicted that the change back to pre-pandemic conditions will take several years, and so it is a reasonable assumption that disinfectants will be used more frequently for a long time. The presented article initially deals with the possible impacts of the pandemic on aircraft infrastructure—namely, on the influence of disinfectants on the rubber materials used, for example, in conveyor belts. The proposed methodology is based on the Weibull analysis for conveyor belt lifetime prediction regarding the impact of disinfectants. The Weibull distribution is a continuous probability distribution that can be applied as a theoretical model for statistical data processing. It was named after Weibull, who suggested shape, scale, and location parameters that made the distribution meaningful and useful. Currently, this distribution is applied in many areas, such as biology, economics, and hydrology. In engineering applications, it can be used for reliability and survival analysis. It is used mainly in cases where failure time is dependent on the operating hours, cycles, or age of the component. In the reliability area, it can be used, for example, to predict the lifetime or failure time of a component. To show the consequences of material changes due to the use of disinfectants, this article also presents a CAE (Computer Aided Engineering) analysis that was used for the evaluation of other hyperelastic material characteristics. This research is based on the results of experimental measurements, during which the influence of the types of disinfectant commonly used for the elimination of the coronavirus disease on airport conveyor belt rubber segments was tested. From the performed analysis, it was found that the influence of disinfectants on the material characteristics, including material hardness, elasticity, and static and dynamic loading, could be significant. Therefore, the probability of mechanical damage to the rubber part of the conveyor belt becomes higher, and time intervals for the maintenance or repair of airport conveyor belts should be considered.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Simone Rossi ◽  
Gionata Salvietti ◽  
Francesco Neri ◽  
Sara M. Romanella ◽  
Alessandra Cinti ◽  
...  

AbstractIt is likely that when using an artificially augmented hand with six fingers, the natural five plus a robotic one, corticospinal motor synergies controlling grasping actions might be different. However, no direct neurophysiological evidence for this reasonable assumption is available yet. We used transcranial magnetic stimulation of the primary motor cortex to directly address this issue during motor imagery of objects’ grasping actions performed with or without the Soft Sixth Finger (SSF). The SSF is a wearable robotic additional thumb patented for helping patients with hand paresis and inherent loss of thumb opposition abilities. To this aim, we capitalized from the solid notion that neural circuits and mechanisms underlying motor imagery overlap those of physiological voluntary actions. After a few minutes of training, healthy humans wearing the SSF rapidly reshaped the pattern of corticospinal outputs towards forearm and hand muscles governing imagined grasping actions of different objects, suggesting the possibility that the extra finger might rapidly be encoded into the user’s body schema, which is integral part of the frontal-parietal grasping network. Such neural signatures might explain how the motor system of human beings is open to very quickly welcoming emerging augmentative bioartificial corticospinal grasping strategies. Such an ability might represent the functional substrate of a final common pathway the brain might count on towards new interactions with the surrounding objects within the peripersonal space. Findings provide a neurophysiological framework for implementing augmentative robotic tools in humans and for the exploitation of the SSF in conceptually new rehabilitation settings.


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