Biologically active prostaglandins from some new odd-numbered essential fatty acids

2010 ◽  
Vol 87 (4) ◽  
pp. 461-480 ◽  
Author(s):  
R. K. Beerthuis ◽  
D. H. Nugteren ◽  
H. J. J. Pabon ◽  
D. A. van Dorp
Keyword(s):  
Fatty Acids ◽  
Essential Fatty Acids ◽  
Biologically Active

Evaluation of the composition of essential fatty acids in the tissues of rainbow trout (Oncorhynchus mykiss) grown in closed water supply units

2021 ◽  
Vol 325 (4) ◽  
pp. 495-501
Author(s):  
E.A. Zykina ◽  
M.V. Gurin
Keyword(s):  
Fatty Acids ◽  
Rainbow Trout ◽  
Water Supply ◽  
Oncorhynchus Mykiss ◽  
Fish Oil ◽  
Essential Fatty Acids ◽  
The Body ◽  
Biologically Active ◽  
Rainbow Trout Oncorhynchus Mykiss ◽  
Aquaculture Products

Recently, the task of artificial cultivation of especially valuable fish species in aquaculture has become more and more urgent. The value of salmon fish, and in particular rainbow trout Oncorhynchus mykiss (Walbaum, 1792) available for breeding, is largely determined by the high content of biologically active essential and polyunsaturated fatty acids of the group ω-6 and ω-3, necessary for vital activity and not synthesized by the human body. Since the natural stocks of many popular fatty fish have decreased, farmed fish can help meet consumer demand for this product. Based on this, the assessment of the content of the main ω-6 and ω-3 fatty acids in the fat of rainbow trout grown in closed-loop water supply installations (USV) was made. The fat was extracted from the fish by thermal method with further distillation by supercritical fluid extraction on the SFT-150 unit. The ratio of fatty acids in the fish oil sample was determined using the Chromatek-Kristall-5000 M hardware and software complex. The results obtained were compared with the standard for salmon fish oil “Aquaculture products” and “Wild fish”. It is established that trout cultivated in the UZV in the Penza region, in terms of the content of the main essential fatty acids, is not inferior to the quality indicators of the standard in terms of the requirements for salmon fish of “Aquaculture products”. In fish, all essential fatty acids are present in sufficient quantities, the ratio of ω-6 to ω-3 is 2.6:1, which indicates a high nutritional value of the product and allows it to be used in human food to provide the body with essential fatty acids, as well as a raw material for obtaining therapeutic and preventive products.

scholarly journals BIOLOGICAL ACTIVE COMPOUNDS SALSOLA TRAGUS L. (CHENOPODIACEAE) AS A PROMISING PHARMACOLOGICAL OBJECT OF UKRAINE

2021 ◽  
Vol 26 (2(49)) ◽  
pp. 23-42
Author(s):  
N. A. Kyrylenko ◽  
F. P. Tkachenko ◽  
О. О. Molodchenkova ◽  
S. V. Baieva
Keyword(s):  
Fatty Acids ◽  
Phenolic Compounds ◽  
Unsaturated Fatty Acids ◽  
Essential Fatty Acids ◽  
Total Content ◽  
Biologically Active Compounds ◽  
Biologically Active ◽  
Raw Material ◽  
The Black Sea ◽  
Active Compounds

Introduction. Evaluation of high-quality composition and content of biologically active compounds of Salsola tragus grass as promising raw materials for the pharmaceutical industry. Aim. To determine the chemical composition of the above-ground part of the Black Sea species of S. tragus for the purpose of its use in medicine. Materials and Methods. The study of biologically active compounds S. tragus were conducted in the summer of 2020. Grass samples were collected along the field road near the coast of the Tiligul estuary. The above-ground biomass of this species was analysed. The total content of lipids and their fatty acid composition, the content of carbohydrates, phenolic compounds and their derivatives were studied by generally accepted methods. The acidity titre was determined using a solution of oxalic acid. Main results. 11 compounds of phenolic nature, among which 5 phenoloxides (ferulic, cinnamic, caffeic, gallic and chicoric), 1 coumarin (esculetin) and 5 flavonoids (quercetin, rutin, luteolin-7-glucoside, hyperoside, hesperedin) were identified and quantitatively determined. Ferulic and gallic acid prevail among phenolic acids. Among the flavonoids luteoline-7-glucoside and hesperedin prevailed. Grass S. tragus was quite rich on lipid components. In their composition, 8 fatty acids were found. The content was dominated by unsaturated fatty acids with the domination of linoleic and oleic acids – 27.67 and 19.27 % respectively. The largest content among the investigated biologically active compounds of S. tragus belongs to the total carbohydrates (8.31%). The titre of raw material was 1.8%. Conclusions. On the basis of a comprehensive study of biologically active compounds of grass S. Tragus it is possible to conclude that it can be used as a source of phenolic compounds, in particular flavonoids having a significant antioxidant, anti-inflammatory, antitumor, antimony activity, and oleic acid, which positively affects the exchange of cholesterol and essential fatty acids (ω-3 and ω-6) for the production of new phytomedications.

scholarly journals Microalgae as a Potential Source of Bioactive Food Compounds

2021 ◽  
Vol 9 (3) ◽  
pp. 917-927
Author(s):  
Manishaa Sri Mahendran ◽  
Anto Cordelia Tanislaus Antony Dhanapal ◽  
Ling Shing Wong ◽  
Govindaraju Kasivelu ◽  
Sinouvassane Djearamane
Keyword(s):  
Waste Water ◽  
Fatty Acids ◽  
Essential Fatty Acids ◽  
Review Article ◽  
Biologically Active ◽  
Research Focus ◽  
Healthy Life ◽  
Global Food Security ◽  
Potential Source ◽  
Global Food

Microalgae are unicellular, photosynthethic organisms that can grow on diverse aquatic habitatss like ponds, lakes, rivers, oceans, waste water and humid soils. Recently, microalgae are gaining importance as renewable sources of biologically active food compounds such as polysaccharides, proteins, essential fatty acids, biopigments such as chlorophylls, carotenoids, astaxanthin, as well as vitamins and minerals.The bioactive food compounds of microalgae enable them to be part of multitude of applications in numerous industrial products for healthy life and ecosystem. This review article summarizes the applications of biologically active food compounds derived from microalgae as nutraceuticals, healthy dietary supplements, pharmaceuticals and cosmetics. Further, this review article highlights the importance of research focus on the identification and extraction of bioactive food compounds from the huge numbers of microlage that exist in nature for sustainable global food security and economy.

scholarly journals Biologically active components and health benefits of nettle seed oil

2020 ◽  
Vol 71 (1) ◽  
pp. 347
Author(s):  
Zh. Y. Petkova ◽  
G. A. Antova ◽  
M. Y. Angelova-Romova
Keyword(s):  
Fatty Acids ◽  
Nutritional Value ◽  
Seed Oil ◽  
Essential Fatty Acids ◽  
Saturated Fatty Acids ◽  
Health Benefits ◽  
Pharmaceutical Products ◽  
Biologically Active ◽  
Active Components ◽  
Main Component

The biologically active components of nettle seed oil and important lipid indices, which are criteria for the health benefits of the oil, have been examined. Linoleic acid predominates in triacylglycerols (77.7%), followed by oleic (16.2%). Sterols in the lipids are present at 1.1% and β-sitosterol is the main component (90.1%). The oil contains 711 mg/kg tocopherols and γ-tocopherol predominates (36.1%), followed by α-tocopherol (28.9%) and δ-tocopherol (26.9%). Atherogenicity and thrombogenicity index values are significantly low, which determine the best anti-atherogenic and anti-thrombogenic properties of the oil. The cholesterolemic index and the ratio of polyunsaturated and saturated fatty acids are considerably higher than 1.0 and reveal good hypocholesterolemic potential and nutritional value. The content of biologically active components of nettle seed oil indicates that it is a rich source of essential fatty acids, sterols and tocopherols and this oil can be used in food, cosmetics, and pharmaceutical products.

scholarly journals Development of technology for producing essential fatty acids from hydrolysates of high-fat fish

2021 ◽  
Vol 23 (2) ◽  
pp. 119-130
Author(s):  
Elena E. Kuprina ◽  
Evgeniya S. Grishina ◽  
Anastasia N. Yakkola ◽  
Andrey N. Manuilov ◽  
Pavel I. Demidov ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Fish Oil ◽  
Electrochemical Method ◽  
Essential Fatty Acids ◽  
Daily Intake ◽  
Food Products ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
Omega 3 ◽  
Active Substances

The technology for obtaining biologically active substances of a lipoid nature, enriched with omega-3 acids, from waste from the processing of hydrobionts by means of electrochemical hydrolysis and cryoconcentration has been developed. A comparative analysis of the composition of wastes from cutting herring and trout is carried out, and the expediency of their use for obtaining biologically active substances of a lipoid nature is shown. A technological scheme has been developed and fat yields have been determined when it is obtained from fish waste by an electrochemical method. The fatty acid composition of the fat obtained by the electrochemical method has been determined. It was found that cryoconcentrated fat obtained from wastes from trout and herring cutting by the electrochemical method has a significantly increased content of omega-3 acids and, accordingly, biological value compared to edible and medical fish oil from the liver of the cod family. It was found that during cryoconcentration, the concentration of polyunsaturated fatty acids increases, reaching values close to 90%, which allows the resulting product to be classified as biologically active additives. It was shown by calculation that to create functional fish-based food products from fish of the salmon family, it is sufficient to introduce 4 g of the obtained biologically active additive per 100 g of the product. There is also an improvement in the organoleptic properties of foods from lean fish species. It has been shown that in order to meet 30% of the recommended daily intake of omega-3 acids in the development of functional food products based on rainbow trout and Atlantic herring, it is necessary to introduce 1.98 g and 1.8 g of cryoconcentrated fish oil. After encapsulation in nanocapsules, the drug will be suitable for enrichment with omega-3 acids in any food products, which is the subject of further research.

Neonatal nutritional strategy of a viviparous elasmobranch with extremely low reproductive output

2020 ◽  
Vol 638 ◽  
pp. 107-121 ◽  
Author(s):  
BS Rangel ◽  
NE Hussey ◽  
Y Niella ◽  
LA Martinelli ◽  
AD Gomes ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Reproductive Strategies ◽  
Trophic Ecology ◽  
Essential Fatty Acids ◽  
Physiological State ◽  
Maternal Investment ◽  
Early Life History ◽  
Nutritional State ◽  
Disc Width ◽  
Biomarker Analysis

Throughout evolutionary history, elasmobranchs have developed diverse reproductive strategies. Little focused work, however, has addressed how neonatal nutritional state is affected by differing degrees of maternal investment associated with these markedly different reproductive strategies. To investigate the effect of maternal investment on the nutritional quality of pups during the early life history of an extremely viviparous elasmobranch, quantitative biomarker analysis including lipids, fatty acids and stable isotopes was conducted. Using the cownose ray Rhinoptera bonasus (histotrophic viviparous) as a model, we found that pups were initially born in a positive nutritional state, enriched in physiologically important essential fatty acids and nitrogen and carbon stable isotope values (δ15N and δ13C), a result of maternal intrauterine transfer. A systematic decrease in some fatty acids and δ15N values, as well as a decrease in cholesterol with growth, confirmed that these substrates were derived from maternal resources and used in initial metabolic processes following birth. An observed increase in condition factor, plasma essential fatty acids and triglyceride:cholesterol ratio with increasing body size identified a progression towards successful independent foraging with pups not displaying marked nutritional deficiency or fasting phases. Our multi-tracer approach allowed the identification of 2 size classes of young rays (<50 and <70 cm disc width) that displayed distinct physiological states. Since prenatal maternal investment is critical for offspring condition and to promote successful foraging post birth, understanding the trophic ecology and physiological state of pups during their first year is critical to guide management and conservation within nursery grounds.

USE OF ESSENTIAL FATTY ACIDS AND THEIR ROLE IN THE HUMAN ORGANISM DEVELOPMENT

2018 ◽  
Vol 28 (4) ◽  
pp. 1219-1225
Author(s):  
Filip Jovanovski ◽  
Toni Mitrovski ◽  
Viktorija Bezhovska
Keyword(s):  
Fatty Acids ◽  
Unsaturated Fatty Acids ◽  
Essential Fatty Acids ◽  
Normal Growth ◽  
The Body ◽  
Human Nutrition ◽  
Human Organism ◽  
Working Ability ◽  
The World ◽  
Growth Development

Food is not just a pleasure in life, it is also an important factor for our health. Human nutrition is a mixture of nutrients, which are the only source of energy needed for survival. Energy-poor diet endangers many life functions, and above all the working ability. In the world, the meaning of the diet is very serious, and hence the demands for a –rational, healthy and safe diet are growing. Human nutrition contains saturated and unsaturated fatty acids. Essential fatty acids (EFAs) must be ingested in everyday diet because the body does not produce it. They are very important for human health. They are present in each cell of the human body and are an important factor for the normal growth, development and functioning of cells, muscles, nerves and organs. They are also used in the production of certain hormones - such as prostaglandins, which are crucial for the performance of certain important processes. The deficit from EFAs is due to a number of health problems, including more serious diseases.

Chlorella vulgaris as a Source of Essential Fatty Acids and Micronutrients: A Brief Commentary

2017 ◽  
Vol 10 (1) ◽  
pp. 92-99 ◽  
Author(s):  
Hércules Rezende Freitas
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Culture Medium ◽  
Essential Fatty Acids ◽  
Total Lipid Content ◽  
Dietary Quality ◽  
Negative Effects ◽  
Algae Biomass ◽  
Dietary Consumption ◽  
Acid Consumption

Polyunsaturated fatty acids (PUFAs) comprise about 35-40% of the total lipid content from green algaeChlorella, reaching up to 24% linoleic acid and 27% α-linolenic acid inC. vulgaris. Also, microalgae nutrient composition may be modulated by changes in the culture medium, increasing fatty acid and microelement concentrations in the algae biomass. PUFAs, such as α-linolenic (n-3) and linoleic (n-6) acids, as well as its derivatives, are considered essential for dietary consumption, and their ability to regulate body chemistry has been recently explored in depth. A balanced fatty acid consumption is shown to counteract the negative effects of western diets, such as chronic inflammation and glucose intolerance. In this brief commentary, technological and practical uses ofC. vulgarisare explored as means to improve dietary quality and, ultimately, human health.

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