Prevalence of Obesity and the Metabolic Syndrome

Author(s):  
Ali H. Mokdad ◽  
Earl S. Ford
2012 ◽  
Vol 2012 ◽  
pp. 1-9 ◽  
Author(s):  
Heather A. LaGuardia ◽  
L. Lee Hamm ◽  
Jing Chen

Metabolic syndrome is characterized by a clustering of cardiovascular risk factors, including abdominal obesity, elevated blood pressure and glucose concentrations, and dyslipidemia. The presence of this clinical entity is becoming more pervasive throughout the globe as the prevalence of obesity increases worldwide. Moreover, there is increased recognition of the complications and mortality related to this syndrome. This paper looks to examine the link between metabolic syndrome and the development of chronic kidney disease.


Author(s):  
Vikram Singh ◽  
Mridu Singh ◽  
Anil Joshi ◽  
Chitra Joshi

Background: There are enormous studies on various aspect of Diabetes and Metabolic syndrome, majority of studies are on urban population, few in rural area but very few for the population living in far flung hilly region of Himalaya. The aim was to find the prevalence of different components of metabolic syndrome in Type 2 diabetics living in the hills of Himalaya and to find correlation with obesity.Methods: All the Type 2 Diabetic patients age 35 years and above attending the inpatients and out patient’s department of V. C. S. G. G. M. C and RI Srinagar, Uttarakhand from October 2012 to March 2013 were enrolled and were evaluated for metabolic syndrome by IDF (International Diabetes Federation) criteria.Results: 128 diabetics were enrolled (76 males and 52 females), the prevalence of obesity in patients of type 2 diabetics was 45.3%. There was poor correlation between obesity and type 2 diabetes (correlation coefficient 0.08) The prevalence of metabolic syndrome was 40.6 % and high percentage (62%) had all five components of the syndrome.Conclusions: The prevalence of obesity and Metabolic syndrome is relatively lower in Type 2 Diabetics of Shivalik range of Himalaya (Uttarakhand).


Author(s):  
Vittoria Infantino ◽  
Antonella Riva ◽  
Giovanna Petrangolini ◽  
Pietro Allegrini ◽  
Simone Perna ◽  
...  

: The increased prevalence of obesity, metabolic syndrome and type 2 diabetes has prompted scientists to look for new active and safe molecules that may help the prevention of metabolic disorders: hyperglycemia, insulin-resistance, dyslipidemia. Berberine is an alkaloid compound derived from plants, and it is largely used in traditional chinese medicine. The aim of this study is to investigate in SCOPUS and Web of Science (WOS) databases how the scientists focused on the use of berberine against metabolic disorders, in human subjects. We carried A bibliometric analysis of scientific literature and performed 2 searches: 1) “Berberine” AND “Diabetes” AND “Diabetes Type 2”, 2) “Berberine” AND “Metabolic Syndrome”, both in ARTICLE (Title/Abstract/Keyword) with a time limitation of 1 January 2000 through 31 December 2018, with the filter on “HUMAN” AND/OR “HUMANS”. The research sorted out 500 papers, finding about 300 (60 %) in the first search definition, and 200 (40 %) in the second. The refined research sorted out 46 papers regarding the use of berberine in diabetes, and 40 articles on the use of the alkaloid compound in the metabolic Syndrome. For both topics, we found increasing interest between 2008 and 2009, with citation trends in a constant crescendo in the overall period studied. These findings underlined that berberine is a safe and interesting botanical compound, especially against chronic-metabolic disorder that affects billions of people globally, and emphasized that scientists are interested in searching for long-term therapies that show no major adverse effects.


2009 ◽  
Vol 2009 ◽  
pp. 1-5 ◽  
Author(s):  
F. Sharifi ◽  
S. N. Mousavinasab ◽  
M. Saeini ◽  
M. Dinmohammadi

Objectives. We determine the prevalence of the metabolic syndrome in an urban population of Zanjan, a province located to the west of Tehran.Methods. Randomly selected adults>20 years were studied using stratified sampling. Target study sample was 2941 (1396 males and 1545 females). Metabolic syndrome was diagnosed using Adult Treatment Panel-III (ATP-III) guidelines when any three of the following were present: central obesity, raised triglycerides≥150 mg/dl, low high-density lipoprotein (HDL) cholesterol, blood pressure≥130/≥85 mm Hg, and diabetes or fasting plasma glucose (FPG)≥100 mg/dl.Results. Metabolic syndrome was present in 697 (23.7%) subjects (CI 95%:22%–25%,P= .001), prevalence was 23.1% in men and 24.4% in women (P: .4). The prevalence increased from 7.5% in the population younger than 30 y to 45.6% in ages more than 50 years. Low HDL was the most common metabolic abnormality in both sexes. Most of those with metabolic syndrome had three components of the syndrome (75.6%), 170 subjects (24.4%) had four and none had five components simultaneously. The prevalence of obesity (BMI≥30 kg/m2), hypercholesterolemia (≥200 mg/dl) and high LDL cholesterol (≥130 mg/dl) was greater in the metabolic syndrome group than normal subjects (P= .00).Conclusions. There is a high prevalence of metabolic syndrome in this urban population of the northern west of Iran. Focus of cardiovascular prevention should be undertaken in this area.


Author(s):  
Manuel Vaquero Alvarez ◽  
Pilar Aparicio-Martinez ◽  
Francisco Javier Fonseca Pozo ◽  
Joaquín Valle Alonso ◽  
Isabel María Blancas Sánchez ◽  
...  

The prevalence of obesity continues to grow, resulting in metabolic syndrome and increasing economic burden for health systems. The objectives were to measure the ability of the NIM-MetS test, previously used in the adults, for the early and sustainable detection of the Metabolic Syndrome (MetS) in children and adolescents. Moreover, to determine the economic burden of the children with MetS. Furthermore, finally, to use and implement the NIM-MetS test, via a self-created online software, as a new method to determine the risk of MetS in children. The method used was an observational study using different instruments (NIM-MetS test, International Diabetes Federation (IDF), or Cook) and measures (body mass index). Additionally, the economic burden was estimated via a research strategy in different databases, e.g., PubMed, to identify previous papers. The results (N = 265 children, age from 10–12) showed that 23.1% had obesity and 7.2% hypertension. The prevalence of MetS using the NIM-Mets was 5.7, and the cost of these children was approximate 618,253,99 euros. Finally, a model was obtained and later implemented in a web platform via simulation. The NIM-MetS obtained is a non-invasive method for the diagnosis of risk of MetS in children.


2006 ◽  
Vol 9 (8A) ◽  
pp. 1118-1120 ◽  
Author(s):  
Dario Giugliano ◽  
Francesco Giugliano ◽  
Katherine Esposito

AbstractObjectivesTo discuss present knowledge about the relation between sexual dysfunction, metabolic factors and the Mediterranean-style diet.DesignReview of the literature and personal perspectives.Setting and resultsSexual problems appear to be widespread in society, influenced by both health-related and psychosocial factors, and are associated with impaired quality of life. Epidemiological studies suggest that modifiable health behaviours, including physical activity and leanness, are associated with a reduced risk for erectile dysfunction (ED) among men. Data from other surveys also indicate a higher prevalence of impotence in obese men. Obesity and the metabolic syndrome may be a risk factor for ED. The high prevalence of ED in patients with cardiovascular risk factors suggests that abnormalities of the vasodilator system of penile arteries play an important role in the pathophysiology of ED. We have shown that one-third of obese men with ED can regain their sexual activity after 2 years of adopting health behaviours, including a Mediterranean-style diet associated with regular exercise.ConclusionsWestern societies actually spend a huge part of their health care costs on chronic disease treatment and interventions for risk factors. The adoption of healthy lifestyles can reduce the prevalence of obesity and the metabolic syndrome, and hopefully the burden of sexual dysfunction.


2010 ◽  
Vol 2 (3) ◽  
pp. 118 ◽  
Author(s):  
Anna Meiliana ◽  
Andi Wijaya ◽  
Suryani As'ad

BACKGROUND: The increased prevalence of obesity worldwide is correlated with increasing prevalence of metabolic syndrome. Studies of adipose tissue have been improved from an inert energy storage to a metabolic active endocrine organ. Adipokines secreted by this tissue play a role in maintaining metabolic homeostasis. The large mass of visceral fat tissue causing the imbalance of these adipokines leading to metabolic abnormality known as the metabolic syndrome (MetS). This study was performed to understand relationship of proinflammatory adipokines (resistin, TNF-α, RBP4 and visfatin) and anti-inflammatory adipokines (adiponectin and vaspin) in the development of MetS.METHODS: This was a cross-sectional study using 122 central obesity men with waist circumference >90 cm, age from 30–60 years old. Proinflammatory adipokines (resistin, TNF-α, RBP4 and visfatin) and anti-inflammatory adipokines (adiponectin and vaspin) was measured by ELISA method.RESULTS: The crosstab study showed that subjects who have >2 high proinflammatory adipokines (17.3%) has higher MetS prevalence (OR = 1.16; p = 0.72) compare to subjects with <2 high proinflammatory adipokines (14.8%), subjects with low anti-inflammatory adipokines profile (18.9%) has higher prevalence of MetS (OR=1.38; p=0.22) compare to subjects with high anti-inflammatory adipokines (13.7%) and the prevalence of MetS became 1.49 times higher (p=0.24) when we combine the high RBP4 and low adiponectin profile (21.1%) compare to subjects with low RBP4 and high adiponectin (14%).CONCLUSIONS: This study showed that each adipokine was not strong enough to induce MetS, so the interaction between proinflammatory and antiinflammatory adipokines were needed to induce a systemic metabolic abnormality. Thus, the adipokines equilibrium was important to prevent MetS especially in centrally obese subjects.KEYWORDS: obesity, metabolic syndrome, adipokines, resistin, TNF-α, RBP4, visfatin, adiponectin, vaspin


2019 ◽  
Vol 4 (2) ◽  
Author(s):  
Nazwirman Nazwirman ◽  
Juniarti Juniarti ◽  
Yurika Sandra

Obesity is a health problem throughout the world. Obesity as a component of the metabolic syndrome, is very complex and multifactorial. Obesity is generally caused by energy input exceeding the body's use of energy for the sake of basal metabolism, physical activity, food waste disposal and for growth. The city of Tangerang ranks first for the prevalence of obesity from Banten Province. The results of the activity stated that the prevalence of obesity in Taklim women was 44 percent. This program is an empowerment of Majelis Taklim women to overcome and prevent health problems, especially metabolic syndrome by conducting screening and counseling. The result is that participants can know the symptoms and signs of metabolic syndrome through anthropometric measurements and laboratory tests, participants can know how to prevent metabolic syndrome and can provide explanations to the family and the surrounding community about prevention of metabolic syndrome


PPAR Research ◽  
2007 ◽  
Vol 2007 ◽  
pp. 1-12 ◽  
Author(s):  
Jane A. Pinaire ◽  
Anne Reifel-Miller

The increasing prevalence of obesity is a fundamental contributor to the growing prevalence of the metabolic syndrome. Rexinoids, a class of compounds that selectively bind and activate RXR, are being studied as a potential option for the treatment of metabolic syndrome. These compounds have glucose-lowering, insulin-sensitizing, and antiobesity effects in animal models of insulin resistance and type 2 diabetes. However, undesirable side effects such as hypertriglyceridemia and suppression of the thyroid hormone axis also occur. This review examines and compares the effects of four RXR-selective ligands: LGD1069, LG100268, AGN194204, and LG101506, a selective RXR modulator. Similar to selective modulators of other nuclear receptors such as the estrogen receptor (SERMs), LG101506 binding to RXR selectively maintains the desirable characteristic effects of rexinoids while minimizing the undesirable effects. These recent findings suggest that, with continued research efforts, RXR-specific ligands with improved pharmacological profiles may eventually be available as additional treatment options for the current epidemic of obesity, insulin resistance, type 2 diabetes, and all of the associated metabolic sequelae.


2020 ◽  
Vol 26 (4) ◽  
pp. 391-399
Author(s):  
E. Yu Petrischeva ◽  
V. A Ionin ◽  
O. I Bliznuk ◽  
V. A Pavlova ◽  
D. S. Skuridin ◽  
...  

Objective. To evaluate the incidence and causes of atrial fibrillation (AF), including the components of the metabolic syndrome (MS) in patients with this arrhythmia hospitalized in a therapeutic clinic.Design and methods. We performed a retrospective analysis of 10663 case histories of patients hospitalized in a therapeutic clinic during 5 years (from 2014 to 2018). Diagnostics of MS components was performed according to the criteria of IDF (2005).Results. The incidence of AF in hospitalized patients was 12,3 %. The most common diseases associated with AF were: hypertension (HTN) (92,8 %), coronary artery disease (CAD) (54,9 %), obesity (42,2 %) and diabetes mellitus (DM) (30 %). It was found that the incidence of obesity in patients with AF increased by 10 %, and the proportion of patients with 3 or more components of MS increased by 22,9 % for the period from 2014 to 2018. Asymptomatic arrhythmia was observed in 58,9 % patients with AF. A comparative analysis showed that patients with obesity were more likely to experience multiple AF paroxysms per month as compared to patients without obesity: 43/69 (57,9 %) and 37/89 (46,1 %), p = 0,015. The obesity increased the probability of frequent AF paroxysms by 2,32 times (95 % CI 1,22-4,43). Single AF paroxysms without subsequent relapses were more common in patients without obesity than in patients with obesity: 35/89 (34,8 %) and 15/69 (26,1 %), p = 0,029.Conclusions. The incidence of AF in patients hospitalized in a therapeutic clinic is 12,3 %, and the most common diseases associated with AF are HTN, CAD, obesity and DM. The prevalence of obesity and MS in patients with AF increased in 2018 as compared to 2014.


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