Identification of subtypes of Chinese schizophrenia patients before discharge: A cluster analysis

2016 ◽  
Vol 33 (S1) ◽  
pp. s257-s257
Author(s):  
S. Liu ◽  
Z. Li
Keyword(s):  
Cluster Analysis ◽  
Cognitive Function ◽  
Self Efficacy ◽  
Self Management ◽  
Type I ◽  
Type Iv ◽  
Neuropsychological Status ◽  
Management Ability ◽  
Competing Interest ◽  
High Level

IntroductionPeople with schizophrenia is a highly heterogeneous group. Identifying subtypes of people with schizophrenia before discharge may help develop targeted discharge plans.ObjectivesTo explore possible subtypes among people with schizophrenia before discharge by their self-management ability, self-efficacy and cognitive function status.AimsTo identify possible subtypes among people with schizophrenia before discharge.MethodsTotally, 150 Chinese people with schizophrenia before discharged from a tertiary psychiatric hospital in Beijing were assessed by Self-management Instrument for People with Schizophrenia and Repeatable Battery for the Assessment of Neuropsychological Status (RBANS). Cluster analysis using SPSS 20.0 package was performed to categorize subjects based on their scores.ResultsFour different types of subjects were revealed. Type I low cognition with no participation (n = 25), patients’ self-management ability, self-efficacy and cognitive function were very poor; type II medium cognition with blind confidence (n = 42), patients’ self-efficacy was good, while self-management ability was poor and cognitive function is medium; type III high cognition with high level skill (n = 46), patients’ cognitive function, self-management ability and self-efficacy were good; type IV low cognition with medium level skill (n = 37), patients’ cognition was very poor, while self-management ability and self-efficacy were medium. These four types of subjects had significant differences in long-term use of antipsychotics and primary caregivers’ education level (P < 0.05).ConclusionsThe finding of different subtypes of people with schizophrenia presenting in this sample may help health professionals give effective screening and targeted discharge measures which can further promote patients’ recovery and reduce readmission rates.Disclosure of interestThe authors have not supplied their declaration of competing interest.

scholarly journals Pre-service Physical Education Teachers’ self-management ability: a training experience in 3D simulation environments (La competencia de autogestión de los futuros maestros de Educación Física: una experiencia formativa en entornos de simulación 3D)

Retos ◽  
2016 ◽  
pp. 30-34
Author(s):  
Luis Marqués Molías ◽  
Jose Cela Ranilla ◽  
Mercè Gisbert Cervera
Keyword(s):  
Physical Education ◽  
Research Work ◽  
3D Simulation ◽  
Self Management ◽  
Physical Education Teachers ◽  
Training Experience ◽  
Management Ability ◽  
High Level ◽  
Performance Results ◽  
Educación Primaria

This study analyses the differences between pre-service Physical Education Teachers (PET) and other students of Education with regard to the ability of self-management. The sample comprised of 58 Spanish students of Education in their last year at the university. The comparison context was a 3D simulation learning environment. Descriptive statistics and non-parametric tests were conducted to develop this research work. Results showed that this technological environment is a space in which students of Education display a high level of self-management ability performance. Results also evince that PET students present better scores than other students of Education in terms of self-management.Resumen. Este estudio analiza las diferencias entre estudiantes para maestros de Educación Primaria con la especialidad de Educación Física y otros estudiantes de Educación respecto a la competencia de autogestión. En este estudio participaron 58 estudiantes españoles de Educación en su último año de universidad. El contexto en el que se desarrolló la experiencia fue un entorno de aprendizaje de simulación 3D. Para su análisis se realizaron estadísticos descriptivos y pruebas no paramétricas. Los resultados mostraron que este entorno tecnológico es un espacio en el cual los estudiantes de Educación despliegan un alto nivel de desempeño en la competencia de autogestión. Los resultados también ponen de manifiesto que los estudiantes de Educación Física obtienen mejores resultados que estudiantes de otras disciplinas respecto a la competencia de autogestión.

scholarly journals Study on the Correlation among Sleep Quality, Cognitive Function, and Self-Management Ability in Hospitalized Elderly Patients with Coronary Heart Disease

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Zhoumin Shen ◽  
Huali Chen ◽  
Yimin Cai ◽  
Bifang Zhou ◽  
Hongjiao Chen ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Cognitive Function ◽  
Elderly Patients ◽  
Sleep Quality ◽  
Self Management ◽  
Hospitalized Elderly ◽  
Management Ability ◽  
Hospitalized Elderly Patients

Background. Coronary heart disease (CHD) is the leading cause of death worldwide. The incidence of cardiovascular disease is especially common in low-level and middle-income countries. With the increase in the number of patients with CHD and the complexity of treatment on patients with CHD, many hospitals are devoted to developing new models of care and management for patients with CHD. Understanding the unique characteristics of the patient’s condition, including factors related to self-management, cognitive function, and sleep quality, will lead to a substantial reduction in cardiovascular disease and related mortality. Objective. To investigate the correlation among sleep quality, cognitive function, and self-management ability in hospitalized elderly patients with coronary heart disease (CHD). Methods. 120 hospitalized elderly patients with coronary heart disease (CHD) were investigated by using a self-designed general data questionnaire, Pittsburgh Sleep Quality Index (PSQI), Montreal Cognitive Function Assessment (MoCA) scale, and Coronary Heart Disease Self-management Behavior Scale (CSMS). Results. The Spearman analysis showed that sleep quality was positively correlated with cognitive function in hospitalized elderly CHD patients ( P < 0.05 ). Sleep quality was positively correlated with self-management ability in CHD patients ( P < 0.05 ). Conclusion. Improving the cognitive function and self-management ability of elderly patients with coronary heart disease can improve their sleep quality.

Morbidity of aging non-incubated chicken blastoderms: further cytological evidence and interpretation

Development ◽  
1974 ◽  
Vol 32 (3) ◽  
pp. 557-571
Author(s):  
T. Konishi ◽  
I. L. Kosin
Keyword(s):  
Mitotic Activity ◽  
Type I ◽  
Metaphase Chromosomes ◽  
Interphase Nuclei ◽  
Cytological Evidence ◽  
Storage Chamber ◽  
Type Iv ◽  
Plastic Bags ◽  
Cytological Picture ◽  
High Level

Cytological analysis was carried out on the blastodermal cells of White Leghorn eggs ubjected to several pre-incubation treatments. These treatments were storage, ranging from0 days to 4 weeks, together with one or more of the following: (1) variation of ambient temperature (5 °C, 15·5 °C, 24 °C), (2) variation of carbon dioxide level (normal air, 1·5% CO2-enriched air), (3) increased humidity (wrapping in plastic bags). To facilitate analysis, the chromosomal configuration of metaphase cells was classified into four types, I–IV, according to their increasingly ‘abnormal’ appearance, which included condensation, dispersal and/or clumping of chromosomes. In interphase cells, the degree of ‘abnormality’ was rated on the staining capacity and shape of the nuclei. The study yielded the following results. (1) Temperature of storage was the most important single factor determining the state of ‘normality’ of the nuclei. The CO2 level in the storage chamber or the use of plastic bags (toprovide the eggs in storage with a special‘ mini-environment’, believed largely due to increased humidity) had little effect on the cytological picture of the affected blastoderms. (2) As the blastoderms of eggs stored at 15·5 °C aged, the proportion of Type IV chromosomal configurations steadily rose. At 24 °C the aging process frequently followed a different route: both metaphase and post-metaphase chromosomes often simply disintegrated; the progression from Type I to Type IV was not in evidence. Aging at 5 °C resulted in an early appearance of uniformly dark-stained, spherical or oval nuclei. These were similar to those observed in the terminal stages of retrogression seen in the interphase nuclei. (3) During extended storage at 15·5 °C, mitosis was shown to be blocked at metaphase. No active mitoses were observed in the blastoderms of eggs stored at 5 °C. At 24 °C however, limited mitotic activity was present, up to and including anaphase. (4) The presence or absence of a high level of mitotic activity during pre-incubation storage was not crucial to the survival of the blastoderm. However, an environment that permitted limited mitosis was important if the cells were to have the best possible chancefor remaining alive during storage. The CO2 content of the air or the use of plastic bags played no role in this respect. (5) Two explanations, at the nuclear level, are suggested for the observed chain of events in the blastoderm of a stored chicken egg.

Genetic control of the nuda character complex in the genus Avena

1976 ◽  
Vol 86 (2) ◽  
pp. 329-334 ◽  
Author(s):  
H. S. Atiyya ◽  
Watkin Williams
Keyword(s):  
Gene Action ◽  
Major Gene ◽  
Type I ◽  
Loss Of Function ◽  
Type Iv ◽  
Avena Nuda ◽  
Type Gene ◽  
Inhibitor Type ◽  
High Level ◽  
Heterozygous Phenotype

SummaryThe inheritance of the units of the character complex which differentiates Avena nuda from Avena sativa was studied in F1 hybrids and in the F2 generation derived from inter-crossing five cultivars of A. saliva with four cultivars of A. nuda. The 14 derived F1 hybrids could be classified into four types depending on the level of dominance of the sativa or nuda character expression. Type-I hybrids involving the cultivar Milford as parent showed a high level of dominance of the sativa-type expression, whereas the F1 hybrid from the cross, Condor × China, type IV, had the character expression typical of the A. nuda parent. Segregation in the F2 generation indicated that the entire character complex was under the control of a major gene, and supported the suggestion from previous work that modifying genes interact with the major gene to alter the expression of the homozygous nuda genotype towards the heterozygous phenotypeHomozygous nuda and heterozygous genotypes were shown to exhibit a gradient in the expression of the nuda character complex from the apex to the base of the panicle, the nuda-type characters being most pronounced in the apical spikelets. It is suggested that the variation of character expression within single panicles of homozygous nuda and heterozygous genotypes indicates the operation of an inhibitor-type gene action rather than a mutation to loss of function.

Impact of emotional intelligence on level of academic achievement in a sample of Saudi female medical student

2017 ◽  
Vol 41 (S1) ◽  
pp. s908-s909
Author(s):  
E. Soliman ◽  
A. Fayed ◽  
E. Al Mussaed ◽  
H. Alawad ◽  
D. Elradi
Keyword(s):  
Academic Achievement ◽  
Emotional Intelligence ◽  
Medical Students ◽  
Self Efficacy ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Grade Point ◽  
Emotional Quotient Inventory ◽  
Competing Interest ◽  
High Level

BackgroundEmotional intelligence (EI) assessment has become an effective technique in exploring individual competencies. In the medical educational, there is a growing evidence for relation between academic achievement and emotional intelligence.ObjectiveTo examine relation between academic achievement and emotional intelligence among medical students.MethodA cross-sectional study of 189 female university students using paper-based Bar-On Emotional Quotient Inventory: Youth Version was conducted. BarOn EQ-i:YV consists of 7 sub-scores which estimate various domains of emotional intelligence along with general mood. The academic achievement was assessed via self-reported Grade Point Average (GPA).ResultThe average Intrapersonal score of participating students was 14.9 ± 3.4 and Interpersonal was 41.7 ± 4.9. The students scored 32.0 ± 5.0 in stress management scale and 31.9 ± 4 in adaptability. The lowest score achieved in the Emotional Inelegance scale was 32.5 whereas the top score was 71.3. The average general mood was 47.1 ± 6.4 and the positive impression ranged between 6 and 23 (17.3 ± 2.8). Positive week correlations were defined between the GPA and self-efficacy (r = 0.13) and Adaptability (r = 0.08) though these correlations were statistically insignificant (P > 0.05). Linear regression model showed that domains of Bar-On scale could explain up to 33% of changes in GPA (R2 = 0.33) with significant effect of self-efficacy, adaptability and general mood scores (P < 0.05).ConclusionMedical students showed high level of emotional intelligence which positively affect their academic achievement. Therefore, improving the emotional intelligence domains can help students improving their academic achievement.Disclosure of interestThe authors have not supplied their declaration of competing interest.

scholarly journals Commensal Streptococcus mitis produces two different lipoteichoic acids of type I and type IV

2021 ◽  
Author(s):  
Nicolas Gisch ◽  
Katharina Peters ◽  
Simone Thomsen ◽  
Waldemar Vollmer ◽  
Dominik Schwudke ◽  
...  
Keyword(s):  
Lipoteichoic Acid ◽  
Opportunistic Pathogen ◽  
Type I ◽  
Beta Lactam ◽  
Viridans Streptococci ◽  
Glycerol Phosphate ◽  
Streptococcus Mitis ◽  
Antibiotic Resistant ◽  
Type Iv ◽  
High Level

The opportunistic pathogen Streptococcus mitis possesses, like other members of the Mitis group of viridans streptococci, phosphorylcholine (P-Cho)-containing teichoic acids (TAs) in its cell wall. Bioinformatic analyses predicted the presence of TAs that are almost identical with those identified in the pathogen S. pneumoniae, but a detailed analysis of S. mitis lipoteichoic acid (LTA) was not performed to date. Here we determined the structures of LTA from two S. mitis strains, the high-level beta-lactam and multiple antibiotic resistant strain B6 and the penicillin-sensitive strain NCTC10712. In agreement with bioinformatic predictions we found that the structure of one LTA (type IV) was like pneumococcal LTA, except the exchange of a glucose moiety with a galactose within the repeating units. Further genome comparisons suggested that the majority of S. mitis strains should contain the same type IV LTA as S. pneumoniae, providing a more complete understanding of the biosynthesis of these P-Cho-containing TAs in members of the Mitis group of streptococci. Remarkably, we observed besides type IV LTA an additional polymer belonging to LTA type I in both investigated S. mitis strains. This LTA consists of β-galactofuranosyl-(1,3)-diacylglycerol as glycolipid anchor and a poly-glycerol-phosphate chain at the O-6 position of the furanosidic galactose. Hence, these bacteria are capable of synthesizing two different LTA polymers, most likely produced by distinct biosynthesis pathways. Our bioinformatics analysis revealed the prevalence of the LTA synthase LtaS, most probably responsible for the second LTA version (type I), amongst S. mitis and S. pseudopneumoniae strains.

Altered response of progeria fibroblasts to epidermal growth factor

1991 ◽  
Vol 100 (3) ◽  
pp. 649-655
Author(s):  
A. Colige ◽  
B. Nusgens ◽  
C.M. Lapiere
Keyword(s):  
Growth Factor ◽  
Collagen Synthesis ◽  
Type Iv Collagen ◽  
Accelerated Aging ◽  
High Serum ◽  
Population Doubling ◽  
Type I ◽  
Type Iv ◽  
Potent Growth ◽  
High Level

The Hutchinson-Gilford syndrome (progeria) is a rare disorder in childhood characterized by premature and accelerated aging. This study reports the effect of a potent growth factor, EGF, on the proliferative capacities and extracellular matrix macromolecules and collagenase expression of two strains of progeria skin-derived cells. At low population doubling levels (PDL less than 10), confluent cultures of progeria fibroblasts made quiescent by lowering the concentration of serum in the medium did not respond to EGF while the mitotic activity of normal PDL-matched fibroblasts was almost maximally restored upon addition of EGF. No obvious difference between normal and low PDL progeria fibroblasts was observed in the number and in the affinity of the receptors measured by [125I]EGF binding. The synthesis of collagen and non-collagen proteins was similar in normal and affected cells at low and high serum concentration and both types of cells responded to EGF by a specific inhibition of collagen synthesis. Besides a normal level of mRNA coding for type I and type III collagens, collagenase and laminin, progeria fibroblasts expressed a high level of elastin and type IV collagen mRNA. Like normal fibroblasts, progeria cells responded to EGF by a decrease in the level of mRNA for fibrillar collagens and elastin. In contrast, a complete lack of response to EGF was observed for collagenase mRNA whereas the expression of this enzyme was strikingly induced by EGF in normal PDL-matched cells. The abnormal expression of type IV collagen was not significantly modified by EGF. At PDL greater than 10, progeria cells exhibited features of senescence. A significant reduction of collagen synthesis was observed and no further inhibition by EGF was recorded.

scholarly journals Identification of the coal structure and prediction of the fracturability in the No. 8 coal reservoir, Gujiao block, China

2017 ◽  
Vol 36 (2) ◽  
pp. 204-229 ◽  
Author(s):  
Bo Huang ◽  
Yong Qin ◽  
Wanghong Zhang ◽  
Gang Wang
Keyword(s):  
Cluster Analysis ◽  
Travel Time ◽  
Apparent Resistivity ◽  
Structure Identification ◽  
Type I ◽  
Coal Structure ◽  
Type Iv ◽  
Natural Gamma ◽  
Gamma Density ◽  
Coal Reservoir

Five boreholes were selected in the Gujiao block, Xishan, Taiyuan, China, as calibration wells to identify the coal structure. The geophysical-log responses of the coal structure in the No. 8 coal reservoir, Gujiao block, were investigated using coal-core logging combined with actual observations in the borehole profile of the coal mine. Natural gamma, density, apparent resistivity, and sonic travel time logs were extracted at 0.15 m intervals from 41 undeformed coal, 29 cataclastic coal, and 48 granulated coal regions. Box plots and Fisher’s maximum separation criterion were used to screen and identify sensitive log responses of the coal structure. The coal structure was identified in 31 boreholes using the available logs in the block, and the layered distribution patterns of the coal structure were discussed. The fracturability of the coal structure was divided into types using cluster analysis based on the thickness ratio of the coal structure and the relationship between the coal structure and its permeability. The results show that sensitive log responses for identifying undeformed coal and cataclastic coal are natural gamma, followed by density and apparent resistivity; log responses for identifying cataclastic coal and granulated coal-mylonitized coal are sonic travel time, apparent resistivity and natural gamma. The sensitive log response data were integrated and coal structure identification models were constructed based on the principle of amplifying the log responses to identify the coal structure in the No. 8 coal reservoir. The reservoir generally contains two or three dirt bands, and the coal structure is divided into several independent layers, with the cataclastic coal and granulated coal-mylonitized coal distributed in the middle of the reservoir. The coal structure was classified into four types and four subtypes through cluster analysis of the boreholes. Under the control of the Malan syncline, type I and type II are developed in the No. 8 coal reservoir in the southern part of the study area and in the east and north wings of the Malan syncline; they have good fracturability. Type III and type IV are mainly present in the No. 8 coal reservoir at the synclinal axis; they have poor fracturability. For type IV dominated by granulated coal, it is difficult to improve the reservoir permeability by fracturing; therefore, other strengthened permeability-improving measures should be considered.

scholarly journals Effect of Health Education Based on Behavioral Change Theories on Self-Efficacy and Self-Management Behaviors in Patients with Chronic Heart Failure

2019 ◽  
Author(s):  
Hui YU ◽  
Panpan ZHANG ◽  
Xiao WANG ◽  
Yan WANG ◽  
Binyu ZHANG
Keyword(s):  
Heart Failure ◽  
Chronic Heart Failure ◽  
Health Education ◽  
Behavioral Change ◽  
Self Efficacy ◽  
Nursing Intervention ◽  
Self Management ◽  
Control Group ◽  
Observation Group ◽  
Management Ability

Background: We aimed to explore the effect of health education and nursing intervention model based on behavioral change theories on self-efficacy and self-management behaviors in patients with chronic heart failure. Methods: Eighty-six patients with chronic heart failure treated in the First Hospital Affiliated to Harbin Medical University (Harbin, China) from November 2016 to January 2018 were enrolled in this study. The patients were evenly divided into control group and observation group (43 patients in each group), according to the random number table method. Patients in the control group received a routine health education intervention. Patients in the observation group received health education based on behavioral change theories in addition to the routine nursing intervention. The health education included mastering of the disease-related theoretical knowledge, daily self-management and exercising guidance. After 8 weeks of intervention, the self-efficacy level, self-management ability and quality of life were assessed and compared between the two groups. Results: The self-management behavior score in the observation group was higher than those in the control group (P=0.002). The chronic disease general self-efficacy (GSE) score in the observation group was higher than those in the control group (P=0.002). The quality of life (MHL) score was in the observation group was higher than those in the control group. The patient satisfaction score in the observation group was higher than those in the control group (P=0.021). Conclusions: Health education based on behavioral change theories can relieve symptoms of chronic heart failure, and improve patients’ self-efficacy level, self-management ability and patient satisfaction.

Effect Of Nursing Intervention Based on Behavioral Shaping Therapy on Blood Glucose Index, Self-Efficacy and Subjective Well-Being in Elderly Patients with T2DM

2021 ◽  
Vol 7 (5) ◽  
pp. 3204-3211
Author(s):  
Wei Zhang ◽  
Ping Lin ◽  
XiaoYing Zhang ◽  
Zhen Zhao
Keyword(s):  
Blood Glucose ◽  
Elderly Patients ◽  
Self Efficacy ◽  
Well Being ◽  
Nursing Intervention ◽  
Self Management ◽  
Control Group ◽  
Observation Group ◽  
Subjective Well Being ◽  
Management Ability

Objective: To investigate the effect of nursing intervention based on behavioral shaping therapy on blood glucose index, self-efficacy and subjective well-being in elderly patients with type 2 diabetes mellitus (T2DM). Methods: 100 elderly patients with T2DM admitted to our hospital from February 2019 to January 2020 were selected and divided into control group and observation group according to the random number table method, 50 cases in each group. The control group adopted the nursing method of routine education combined with motivation interview, and the observation group adopted the nursing method of behavior shaping on the basis of the control group. The fasting plasma glucose (FPG), 2h postprandial plasma glucose (2h PG), glycosylated hemoglobin (HbAlc) level, self-management ability score, diabetes management self-efficacy scale (DMSES) score and subjective well-being score were compared between the two groups before and after intervention. Results: The levels of FPG, 2h PG and HbAlc in the two groups were significantly decreased, and those of the observation group were significantly lower than those in the control group (P<0.05). After intervention, the total scores of self-management ability, DMSES and subjective well-being of the two groups were significantly increased, and the observation group was significantly higher than the control group (P<0.05). Conclusion: Behavioral shaping therapy combined with routine education and motivation interview can significantly improve the self-management ability, self-efficacy, blood glucose index and subjective well-being of elderly patients.

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