High Prevalence of Valvular Disease Found in the Elderly

2005 ◽  
Vol 38 (1) ◽  
pp. 50
Author(s):  
MITCHEL L. ZOLER
2015 ◽  
Vol 24 ◽  
pp. S188
Author(s):  
D. Colquhoun ◽  
I. Hamilton-Craig ◽  
K. Kostner ◽  
S. Woodhouse ◽  
M. d’Emden

2009 ◽  
Vol 7 (3) ◽  
pp. 139-144
Author(s):  
D. Chatzidimitriou ◽  
M. Exidari ◽  
G. Gioula ◽  
P. Papakonstantinou ◽  
A. Melidou ◽  
...  

The prevalence of IgG and IgA antibodies to Chlamydia pneumoniae was evaluated in a group of an apparently healthy population in northern Greece. Serum samples were obtained over a period of one year (June 2006 to May 2007) from 530 individuals (300 males and 230 females, aged from 1 month to 90 years). The sera were tested for specific antibodies to C. pneumoniae by two commercial methods, an ELISA and a micro-IF assay based on the principles of MIF. The prevalence of IgG and IgA antibodies to C. pneumoniae was 53.2% and 45.9%, respectively, and was found to be unrelated to gender, even in the elderly >61 years old. The IgG antibody prevalence was low in children under 5 years old (7.7%), sharply increased by the age of 20 (40%) and continued to increase, gradually, to reach 80.1% in the elderly. IgA antibodies also increased with similar kinetics to IgG, although at a lower level (3.8–66.1%). Our results show that infection with C. pneumoniae is common in northern Greece. The high prevalence of IgA specific antibodies reported in the present study is due to primary infection at a young age, while in the elderly is probably due to infection or reinfection, although the option of persistence cannot be excluded.


2015 ◽  
Vol 2 (1) ◽  
pp. 18-23
Author(s):  
M. Jahidul Islam ◽  
M. Shahadat Hossain ◽  
M. Ruhul Amin ◽  
Monzur Ahmed

Osteoarthritis (OA) is no longer considered ‘degenerative’ or ‘wear and tear’ arthritis; rather involves dynamic biomechanical, biochemical and cellular process. Indeed, the joint damage that occurs in OA is the result of active remodeling involving all the joint structures. Although articular cartilage is at the center of change, OA is viewed as a disease of the entire joint. Traditionally, OA has been viewed as an inevitable degenerative condition of the cartilage. It is currently viewed as a biomechanical and biochemical inflammatory disease of the entire joints. Osteoarthritis (OA) is the most common type of arthritis. Its high prevalence, especially in the elderly, and the high rate of disability related to disease make it a leading cause of disability in the elderly. Because of the aging of Western populations and because obesity, a major risk factor, are increasing in prevalence, the occurrence of osteoarthritis is on the rise. In the United States, osteoarthritis prevalence will increase from 66–100% by the year 2020. OA affects certain joints, yet spares others. Commonly affected joints include the cervical and lumbosacral spine, hip, knee, and first metatarsal phalangeal joint (MTP). In the hands, the distal and proximal inter-phalangeal joints and the base of the thumb are often affected. Usually spared are the wrist, elbow, and ankle.Journal of Current and Advance Medical Research 2015;2(1):18-23DOI: http://dx.doi.org/10.3329/jcamr.v2i1.22584


2021 ◽  
Author(s):  
Carolina Da Mota Iglesias ◽  
Liara Eickhoff Coppetti ◽  
Marcela Menezes Teixeira ◽  
Paula Loredo Siminovich ◽  
Bernardo Neuhaus Lignati ◽  
...  

Background: In most cases, strokes are events with an abrupt onset characterized by a neurological deficit attributed to a focal vascular cause. Such events can have ischemic or hemorrhagic origin with diagnosis attributed to clinical and imaging exams. In this work, we analyze the profile of deaths by stroke in the Brazilian population, outlining an overview of the disease in Brazil. Objective: Analyze stroke death profiles between the years 2010 and 2019. Methodology: We perform a descriptive documentary study based on the Mortality Information System (SIM) for the years 2010 to 2019, made available by the Brazilian Unified Health System (SUS) Information Department. Our study is delimited by age, starting from 15-year-olds, and considering the ICD-10 I64 pathologies. Results: In the analyzed period, 400.395 stroke deaths were registered. Over the years, these deaths showed a decrease of approximately 24.47% with 2011 being the year with the highest number of registered deaths (n=44 892). The southeast region registered most deaths with 38.18% of the total. The most affected groups were men (50.79%), whites (46.43%), over 80 years-old (41.80%) and with no formal education (27.31%). Conclusion: There is a decrease in stroke cases in Brazil between 2010 and 2019. The high prevalence of deaths from stroke in the elderly highlights the need for greater control of modifiable risk factors to reduce mortality. Thus, the continuous improvement of socioeconomic, educational, and hospital care conditions in Brazil is necessary.


2021 ◽  
Vol 64 (3) ◽  
pp. 62-67
Author(s):  
Ana Popescu ◽  
◽  
Gabriela Soric ◽  
Victoria Federiuc ◽  
Vitalie Ojovanu ◽  
...  

Background: Aging process involves an increased risk for the development of vulnerability, because senescence is a process characterized by a multitude of changes that influence the living conditions and health of the individuals. In geriatrics, the term “vulnerability” implies a multidimensional aspect, among which, multimorbidity, functional incapacity, socio-economic and cognitive problems in the elderly. The main objective of the article is to systematize data from the literature through the analysis of the concept and prevalence of vulnerability, assessed by the score Vulnerable Elders Survey-13 (VES-13) in the elderly. For this purpose, publications from the database GoogleSearch, PubMed, Hinari, etc. were analyzed. The information was systematized, highlighting the main aspects of the contemporary vision of the last 5 years.A series of studies (USA, Brazil, etc.) revealed a high prevalence of vulnerability in the elderly according to the VES-13 score, it was estimated in respondents aged > 65 years, between 40-50% of cases were vulnerable people, with a score ≥ 3 p. The vulnerability of the elderly results from different conditions, correlated with each other, especially biological, social and genetic factors. There was a functional decline between 13 and 24% of cases, especially in the elderly over 75 years, and an association with health problems, mobility and low autonomy in over 50% of cases, with a poor quality of life and increased risk of institutionalization. Conclusions: Vulnerability assessment measures are important for identifying older people at high risk of deteriorating health, which is an important target for interdisciplinary intervention.


2011 ◽  
Vol 27 (9) ◽  
pp. 1819-1826 ◽  
Author(s):  
Fernando Vinholes Siqueira ◽  
Luiz Augusto Facchini ◽  
Denise Silva da Silveira ◽  
Roberto Xavier Piccini ◽  
Elaine Tomasi ◽  
...  

We conducted a cross-sectional study of a sample of 6,616 elderly living in urban areas of 100 municipalities in 23 Brazilian states, who responded to questions on the occurrence of falls in the 12 months prior to the interview, and occurrence of fractures due to the falls. The prevalence of falls among the elderly was 27.6% (95%CI: 26.5-28.7). Among those reporting falls, 11% had suffered fractures as a result. Of the elderly, 36% had received guidance about the precautions necessary to prevent falls, and about 1% had required surgery. Falls were associated with female gender, older age, low socioeconomic status, obesity and sedentary lifestyles. The prevalence of falls differed significantly between the North and other regions of Brazil. The study shows a high prevalence of falls, and underlines the need for preventive strategies targeting modifiable risk factors.


2021 ◽  
Vol SI ◽  
pp. 85-95
Author(s):  
Grace Emmanuel Kaka ◽  
Muhamad Helmi Md Said ◽  
Shahrul Mizan Ismail

The novel coronavirus (Covid-19) led to a shift in the social structure of global cities leading to self-isolation and social/physical distancing to curb the spread of the virus. While these two are stand as good policy, they are greeted by domestic violence and rape as the most prevalent consequences. The researchers examined the impact of lockdown on domestic violence in Nigeria based on frequency of news reports using content analysis of two online news reports and discovered a high prevalence of rape on children (0 - 17 years) and elderly (60 years and above). Hence it is suggested that the government should always be prepared for emergencies. Also, future polices should consider the interest of the most vulnerable in the society by providing safety measures.


2020 ◽  
pp. 030089162094966
Author(s):  
Pietro Gino Barbieri ◽  
Dario Mirabelli

Background: The diagnosis of lung cancer (LC) may be difficult to make in the elderly. We report on the diagnostic elements available in life in an LC necropsy case series of asbestos-exposed workers and describe the frequency of non-neoplastic asbestos-related diseases as biological exposure indices. Methods: We reviewed pathologic and clinical records of an unselected series of autopsies (1997–2016) in patients with LC employed in the Monfalcone shipyards. We assessed the consistency with autopsy results of diagnoses based on, respectively, radiologic, cytologic, and histologic findings. Results: Data on 128 autopsy-confirmed LC cases were available; in life, 119 had been diagnosed as LC. Among these, 49 had histologic confirmation of diagnosis (17 with immunophenotyping); histology had been negative in 4. Cytology had been the main positive finding and the basis for diagnosis in 24 cases, but had been negative in 13. Chest computed tomography had been the basis for diagnosis in 45; in 18 cases, it had been negative. Nine patients had received a diagnosis different from LC, among whom 4 had been suspected to have malignant pleural mesothelioma by chest computed tomography. Pleural plaques were found in 124 and histologic asbestosis in 46 cases. Conclusions: Autopsies confirmed all LC diagnoses received in life, including 46 that would have been considered only possible LC based on clinical workup. The overall survival in this case series was poor. The high prevalence of pleural plaques and asbestosis suggest severity of asbestos exposures.


Author(s):  
Giuliano Pinna ◽  
Claudio Pascale ◽  
Micaela La Regina ◽  
Francesco Orlandini

IntroductionThere is a high prevalence of hypertension in the elderly, as evidenced by clinical and health behavioral policies. Still, there are uncertainties on the treatment of hypertension, especially treatment of the very elderly. These considerations have largely been ignored in clinical trials due to concern regarding contamination by other pathologies that are difficult to frame and manage.Methods We performed an effective and ample literature review and provided reflections on the Consensus Conference ACCF/AHA 2011 on the principle types of hypertension found in the elderly. We also considered the associated principle pathologies for various treatments and related organs.Discussion Even if the goal of treatment of elevated blood pressure in the elderly is same as in younger population, it is no longer certain that a target systolic blood pressure (SBP) <140 mmHg should be persistently reached in the very elderly. It is important to note that for all studies these values have never been reached. In the treatment of isolated systolic hypertension (ISH) the preferred target is a SBP >160 mmHg. Treating hypertension in the elderly and very elderly reduces the risk of stroke and heart failure, though the evidence is inconclusive for all-cause mortality.Conclusion Hypertension in the elderly is very common and needs to be treated with criteria that consider the patient's age, comorbidities, lifestyle and adherence. Above all, in the very elderly, therapeutic treatment should be personalized according to the above criteria. Where possible pharmaceutical therapy should be limited at the preference of healthy lifestyle changes (physical activity, diet, etc.).


1970 ◽  
Vol 9 (1) ◽  
pp. 10-15 ◽  
Author(s):  
Md Titu Miah ◽  
AKM Aminul Hoque ◽  
Binoy Krishna Tarafder ◽  
Syed Mohammad Ali Romel ◽  
Md Kamrul Hassan

Stroke in young age is relatively uncommon but has serious impact on the affected family as well as society. The causes are more diversed and differ as compared to the elderly. Overall prognosis is better than elderly but there is still significant morbidity and mortality. We studied consecutive 50 stroke patients between the age of 15-45 admitted in Mymensingh Medical College Hospital. The objective of this study was to evaluate the aetiological pattern, associated risk factors and inpatient outcome. Mean age of the patients was 35.8 ± 7.39 SD ( years ), female male ratio was 1 : 1.27. Infarction was found in 60% cases. Haemorrhage was in 40% cases. Dyslipidaemia was mostly associated risk factor in both infarction (83.3%) and in haemorrhage (75%). In 74% cases aetiology could not be identified. High prevalence of dyslipidemia as associated risk factor may indicate premature atherosclerosis. Overall in-patient mortality was12% .Mortality in haemorrhagic strokes is higher.   DOI = 10.3329/jom.v9i1.1419 J MEDICINE 2008; 9 : 10-15


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