scholarly journals Energy adjustment of nutrient intakes is preferable to adjustment using body weight and physical activity in epidemiological analyses

2013 ◽  
Vol 17 (5) ◽  
pp. 1054-1060 ◽  
Author(s):  
Jinnie J Rhee ◽  
Eunyoung Cho ◽  
Walter C Willett

AbstractObjectiveAdjustment for body weight and physical activity has been suggested as an alternative to adjusting for reported energy intake in nutritional epidemiology. We examined which of these approaches would yield stronger correlations between nutrients and their biomarkers.DesignA cross-sectional study in which dietary fatty acids, carotenoids and retinol were adjusted for reported energy intake and, separately, for weight and physical activity using the residual method. Correlations between adjusted nutrients and their biomarkers were examined.SettingUSA.SubjectsCases and controls from a nested case–control study of erythrocyte fatty acids and CHD (n 442) and of plasma carotenoids and retinol and breast cancer (n 1254).ResultsCorrelations between intakes and plasma levels of trans-fatty acids were 0·30 (energy-adjusted) and 0·16 (weight- and activity-adjusted); for erythrocyte levels, the corresponding correlations were 0·37 and 0·25. Energy-adjusted intakes of linoleic acid and α-linolenic acid were more strongly correlated with their respective biomarkers than weight- and activity-adjusted intakes, but the differences were not significant except for linoleic acid (erythrocyte). Weight- and activity-adjusted DHA intake was slightly more strongly correlated with its plasma biomarker than energy-adjusted intake (0·37 v. 0·34). Neither method made a difference for DHA (erythrocyte), carotenoids and retinol.ConclusionsThe effect of energy adjustment depends on the nutrient under investigation, and adjustment for energy calculated from the same questionnaire used to estimate nutrient intakes improves the correlation of some nutrients with their biomarkers appreciably. For the nutrients examined, adjustment using weight and physical activity had at most a small effect on these correlations.

2003 ◽  
Vol 88 (12) ◽  
pp. 5914-5920 ◽  
Author(s):  
Yumi Matsushita ◽  
Tetsuji Yokoyama ◽  
Nobuo Yoshiike ◽  
Yasuhiro Matsumura ◽  
Chigusa Date ◽  
...  

Abstract The β3-adrenergic receptor (ADRB3) is expressed mainly in visceral adipose tissue and is thought to contribute to lipolysis and the delivery of free fatty acids to the portal vein. Although many studies have examined the relationship between the Trp64Arg mutation of ADRB3 and obesity, the results have been inconsistent. We examined the cross-sectional relationship of ADRB3 variants with indexes of obesity, and their longitudinal changes over 10 yr, in men and women, aged 40–69 yr, who were randomly selected from the Japanese rural population. The study considered both dietary energy intake and physical activity levels. Among the 746 participants, the genotype frequencies of the Trp64Trp, Trp64Arg, and Arg64Arg variants were 483, 224, and 39, respectively. The cross-sectional analysis showed no significant differences in height, weight, body mass index, blood pressure, serum total and high density lipoprotein cholesterols, and hemoglobin A1c among the genotype groups even after adjustments for gender, age, smoking, alcohol drinking, physical activity, and energy intake. No significant differences in the weight changes between the genotype groups were evident in the longitudinal analysis. We conclude that the Trp64Arg mutation of ADRB3 has little or no influence on either body weight or body mass index in the general Japanese population.


2020 ◽  
Vol 23 (9) ◽  
pp. 1657-1663
Author(s):  
Sehrish Naveed ◽  
Taisa Venäläinen ◽  
Aino-Maija Eloranta ◽  
Arja T Erkkilä ◽  
Henna Jalkanen ◽  
...  

AbstractObjective:To investigate the cross-sectional associations of dietary carbohydrate and fatty acid intakes with cognition in mid-childhood.Design:Dietary carbohydrate and fatty acid intakes were assessed using 4-d food records, and cognition was evaluated using the Raven’s Coloured Progressive Matrices (RCPM) score. The cross-sectional associations of dietary carbohydrate and fatty acid intakes with cognition were investigated using linear regression analyses adjusted for age, sex, body fat percentage, household income, parental education and daily energy intake.Setting:The baseline examinations of the Physical Activity and Nutrition in Children study.Participants:A population-based sample of 487 children (250 boys, 237 girls) aged 6–8 years living in the city of Kuopio, Finland.Results:A higher dietary intake of fructose (standardised regression coefficient, β = 0·24, P < 0·001), total fibre (β = 0·16, P = 0·02) and soluble fibre (β = 0·15, P = 0·02) was associated with a higher RCPM score in boys. Other dietary carbohydrates and fatty acids, including total carbohydrates, glucose, sucrose, starch, insoluble fibre, total fat, SFAs, MUFAs, PUFAs, palmitic acid (C16), stearic acid (C18), linoleic acid (C18:2), α-linoleic acid (C18:3), arachidonic acid (C20:4), EPA (C20:5n-3) and DHA (C22:6n-6), were not associated with the RCPM score in boys. Dietary carbohydrates or fatty acids were not associated with the RCPM score in girls.Conclusions:Higher dietary fructose and fibre intakes were associated with better cognition in boys, but not in girls. Dietary fatty acids were not related to cognition in boys or in girls.


Author(s):  
Surabhi Bhutani ◽  
Jamie A Cooper ◽  
Michelle R Vandellen

ABSTRACTBackgroundThe COVID-19 pandemic has caused people to shelter-at-home for an extended period, resulting in a sudden rise in unstructured time. This unexpected disruption in everyday life has raised concerns about weight management, especially in high-risk populations of women and individuals with overweight and obesity. This study aimed to investigate the changes in behaviors that may impact energy intake and/or energy expenditure in U.S. adults during the home confinement.MethodsCross-sectional data from 1,779 adults were collected using an online Qualtrics survey between April 24th and May 4th, 2020. Self-reported data on demographics, eating behaviors, physical activity, sleep, screen time, takeout food intake, and food purchasing behaviors were collected. Chi-Square analyses were conducted to evaluate differences in the percent of participants reporting increasing, decreasing, or staying the same in each health behavior since the COVID-19 outbreak in their area. Each analysis was followed by comparing whether increases or decreases were more likely for each health behavior. Similar comparisons were made between male and female participants and between body mass index (BMI) categories.ResultsWe observed an increase in the intake of both healthy and energy-dense unhealthy foods and snacks during the home confinement. Participants also reported increases in sedentary activities and decrease in physical activity, alcohol intake, and consumption of takeout meals during this time. In women, several behavioral changes support greater energy intake and less energy expenditure than men. No clear difference in patterns was observed across BMI status.ConclusionAcute changes in behaviors underscore the significance of a sudden increase in unstructured time at home on potential weight gain. Our findings support the need to implement and support measures that promote strategies to maintain body weight and establish a methodology to collect body weight data at multiple time points to longitudinally assess the dynamic relationship between behaviors and body weight change.


2010 ◽  
Vol 14 (5) ◽  
pp. 904-913 ◽  
Author(s):  
Léonie N Dapi ◽  
Agneta Hörnell ◽  
Urban Janlert ◽  
Hans Stenlund ◽  
Christel Larsson

AbstractObjectiveTo assess energy and nutrient intakes and physical activity of adolescents in urban Cameroon according to sex and socio-economic status (SES).DesignCross-sectional study with adolescents randomly selected from schools in low-, middle- and high-SES areas. Weight and height were measured and information about food intake and physical activity was obtained through repeated individual 24 h recalls. Under- and over-reporting of energy intake and inadequacy of nutrient intake were assessed.SettingYaoundé, Cameroon.SubjectsBoys and girls aged 12–16 years (n227).ResultsBoys had a lower BMI and reported higher energy expenditures and physical activity levels (PAL) than girls. Under-reporting of energy intake was large among boys and girls regardless of PAL; boys under-reported more than girls. Among those with low PAL, over-reporting of energy intake was common. Over 50 % of boys and girls had protein below the recommendations. The intake of fat varied; 26 % of the adolescents were below and 25 % were above the recommendations. Inadequate intakes of vitamin B1, vitamin B3and Fe were more common among girls, while boys more often had inadequate intake of vitamin A. Adolescents with low SES were more likely to be below the recommendations for fat and vitamins B2, B3, B6and B12than those with high SES.ConclusionsA high proportion of boys and girls reported inadequate intakes. However under- and over-reporting were also very common. Boys under-reported energy intake more than girls and inadequate nutrient intake was more frequently reported by adolescents with low SES than by those with high SES.


2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 1038-1038
Author(s):  
Michael Miklus ◽  
Pedro Prieto ◽  
Cynthia Barber ◽  
Robert Rhoads ◽  
Samer El-Kadi

Abstract Objectives The objectives of this study were to determine the effect of 2’fucosyllactose (2’FL) and fat blends on growth, body composition and fatty acid profile of the liver and brain using the neonatal pig as a model for the human infant. Methods Pigs (3 d old) were randomly assigned to either: 1. control, 2. Palm Olein (PO) fat blend – Low 2'-FL, 3. PO – High 2'-FL, 4. High oleic acid (HO) – Low 2'-FL, 5. HO FB – High 2'-FL, 6. PO FB – GLA, or 7. kept with their sows. Pigs in groups 1 to 6 received 250 ml·kg−1·d−1 of formula in 5 equal meals for 15 d. On day 14 of the study, groups 1–6 received intraperitoneal E. coli LPS challenge at 100 µg·kg−1 weight. Results Body weight was greater for piglets fed by sows than those in the other groups (P &lt; 0.001). In addition, % fat and bone mineral content were higher in the sow-fed group while lean % was less sow-fed piglets (group 7) compared with those in the other groups (P &lt; 0.05). Only longissimus weight expressed as a % of body weight, was greater for group 7 compared with all other groups (P &lt; 0.001). Soleus, semitendinosus, brain, heart and spleen weights as a % of body weight were similar across all groups. However, liver weight as a % of body weight was greater in groups 1–6 (3.7%) compared with group 7 (2.8%; P &lt; 0.001). The proportion of brain 16:1 fatty acid was less (0.83%) for groups 1–6 than for group 7 pigs (1.08%; P &lt; 0.0001). The proportion of 20:3 N6 was greatest (0.66%) for group 3 compared with groups 1 and 4 (0.55%; P &lt; 0.05). In addition, the proportion of 20:5 N3 was greatest (0.12%) for group 3 compared with groups 1 and 7 (0.07%; P &lt; 0.05). The proportion of liver 16:1, 18:0, and 18:1 cis-11 fatty acids were greater for group 7 (2.3, 23, 2.2%) than groups 1–6 (0.2, 20, 1.2%; P &lt; 0.0001). Conversely, the contribution of 14:0, 18:1 cis-9, 18:3 N6 cis-6,9,12, and 22:6 N3 were greater for pigs in groups 1–6 (1.3, 0.6, and 14, 7.8%) compared with those in group 7 (0.5, 8.5, 0.2 and 3.5%; P &lt; 0.0001). Conclusions Our data suggest that feeding 2’fucosyllactose had no effect on the body weight gain and composition in neonatal pigs. Our data also suggest that dietary fatty acids have a greater effect on liver than on brain fatty acid composition. Funding Sources Funding for the work was provided by Perrigo Nutritionals, LLC.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Manar Abduljalil Bakhsh ◽  
Jomana Khawandanah ◽  
Rouba Khalil Naaman ◽  
Shoug Alashmali

Abstract Background The COVID-19 pandemic has forced governments around the world to impose strict hygiene and national lockdown measures, which in turn has changed the dietary and lifestyle habits of the world’s population. Thus, the aim of this study is to evaluate whether dietary and physical activity behaviors of Saudi Arabia’s adult population changed during the COVID-19 quarantine. Methods An electronic questionnaire which assessed changes in body weight, dietary habits, and physical activity of Saudi Arabia’s adult population (n = 2255) during the COVID-19 quarantine was distributed on social media between June and July 2020. To test the differences between changes in dietary and physical activity behaviors in relation to changes in body weight a Chi-square test was used. Results Over 40 and 45% of participants reported eating and snacking more, respectively, which led to weight gain in around 28%. Most participants reported that they consumed home-cooked (73%) and healthy meals (47%), while only 7% reported that they consumed foods from restaurants. Feelings of boredom and emptiness (44%) and the availability of time for preparing meals (40%) were the main reasons for changing dietary habits. Honey (43%) and vitamin C (50%) were the most consumed immune-boosting food and dietary supplement, respectively. COVID-19 also had a negative impact on physical activity, lowering the practice in 52% subjects, which was associated with significant weight gain (p < 0.001). Conclusion Assessing the changes to the population’s dietary habits and physical activity during the lockdown will help predict the outcome of the population’s future health and wellbeing after the pandemic.


2016 ◽  
Vol 41 (6) ◽  
pp. 611-617 ◽  
Author(s):  
Jameason D. Cameron ◽  
Ronald J. Sigal ◽  
Glen P. Kenny ◽  
Angela S. Alberga ◽  
Denis Prud’homme ◽  
...  

There has been renewed interest in examining the relationship between specific components of energy expenditure and the overall influence on energy intake (EI). The purpose of this cross-sectional analysis was to determine the strongest metabolic and anthropometric predictors of EI. It was hypothesized that resting metabolic rate (RMR) and skeletal muscle mass would be the strongest predictors of EI in a sample of overweight and obese adolescents. 304 post-pubertal adolescents (91 boys, 213 girls) aged 16.1 (±1.4) years with body mass index at or above the 95th percentile for age and sex OR at or above the 85th percentile plus an additional diabetes risk factor were measured for body weight, RMR (kcal/day) by indirect calorimetry, body composition by magnetic resonance imaging (fat free mass (FFM), skeletal muscle mass, fat mass (FM), and percentage body fat), and EI (kcal/day) using 3 day food records. Body weight, RMR, FFM, skeletal muscle mass, and FM were all significantly correlated with EI (p < 0.005). After adjusting the model for age, sex, height, and physical activity, only FFM (β = 21.9, p = 0.007) and skeletal muscle mass (β = 25.8, p = 0.02) remained as significant predictors of EI. FFM and skeletal muscle mass also predicted dietary protein and fat intake (p < 0.05), but not carbohydrate intake. In conclusion, with skeletal muscle mass being the best predictor of EI, our results support the hypothesis that the magnitude of the body’s lean tissue is related to absolute levels of EI in a sample of inactive adolescents with obesity.


1998 ◽  
Vol 8 (1) ◽  
pp. 36-48 ◽  
Author(s):  
Jenni M. Felder ◽  
Louise M. Burke ◽  
Brian J. Lowdon ◽  
David Cameron-Smith ◽  
Gregory R. Collier

The aim of this study was to assess the dietary practices of 10 elite female surfers. Four- and five-day food diaries completed over competition and training periods demonstrated energy intakes (mean ± SD) of 9,468 kJ (±2,007) and 8,397 kJ (±1,831), respectively. This level of energy intake was less than that estimated for the requirements of surfing. Female surfers' carbohydrate intakes failed to meet the recommendations, and suboptimal zinc intake was observed with 90% of subjects not meeting the Australian RDI. Comparisons between competition and training demonstrated that carbohydrate (g and g/kg body weight) and confectionary (g) intakes were significantly higher (p < .05) and protein intake was significantly lower (p < .05) during competition. These results show that although body fat stores were not compromised (mean 22%), self-reported energy, carbohydrate, and nutrient intakes were marginal in elite female surfers. Questionnaires revealed that 90% of surfers did not have good nutritional habits while traveling, which was compounded by a lack of knowledge of nutritional practices.


2017 ◽  
Vol 6 (4) ◽  
pp. 268
Author(s):  
Famimah Famimah ◽  
Ani Margawati ◽  
Deny Yudi Fitranti

Background: Dysmenorrhea or menstrual pain was a gynecological complaint due to an imbalance of progesterone in the blood resulting in pain. A woman with dysmenorrhea should consume food rich in omega-3 fatty acids such as fish oil, fish (salmon, tuna, mackerel, herring), soybeans and fruits. Low fish consumption was related with severity of dysmenorrhea. In addition, physical activity and percent body fat were also associated with severity of dysmenorrhea.Objective : To determine the correlation between consumption of omega-3 fatty acids, physical activity and percent body fat to the classification of dysmenorrhea in adolescents.Methods : Cross sectional study of 90 adolescentsselected by purposive sampling. This research was conducted in SMA N 15 and SMA N 9 Semarang. Menstrual history was measured by direct interviews and level of dysmenorrhea was measured using Numerical Rating Scale Questionnaire. Omega-3 fatty acids were measured using Food Frequency Questionnaire (FFQ) and analyzed using a nutritional software program. Physical activity was measured using A short questionnaire for the measurement of habitual physical activity in epidemiological studies. Percent body fat was measured using Bioelectrical Impedance Analysis (BIA). Data were analyzed by Independent T test/Mann Whitney. Result : There were significant correlation in omega-3 fatty acid (p= 0,015), and percent body fat (p= 0,026). While in physical activity there was no significant correlation (p= 0,394).Conclusion : Consumption of omega-3 fatty acids and percent body fat were associated with the classification of dysmenorrhea.


2002 ◽  
Vol 5 (6) ◽  
pp. 747-755 ◽  
Author(s):  
Gemma Cucó ◽  
Joan Fernández-Ballart ◽  
Carles Martí-Henneberg ◽  
Victoria Arija

AbstractObjective:To identify the food that has the greatest effect on the variation in the percentage of energy intake derived from fat and saturated fatty acids for the consumption of a Spanish population.Design:A cross-sectional study of food consumption, using the 24-hour recall method for three non-consecutive days, one of which was a non-working day. Subjects were interviewed by trained interviewers in the subjects' homes. We used multiple linear regression for statistical analysis.Setting:The citizens of Reus.Subjects:One thousand and sixty subjects over five years old, randomly selected from the population census of Reus.Results:In both sexes, the foods that mainly determine a high consumption of fat are oil and red meat while those that determine a lower consumption of fat are bread, savoury cereals and fruit. The foods that mainly determine a high consumption of saturated fatty acids are red meat and whole-fat dairy products while those that determine a low consumption are bread, savoury cereals and fruit.Conclusions:In our population, feasible variations in the intake of some foods – less than one portion – would reduce the estimated percentage of energy intake derived from fat and saturated fatty acids by a quantity considered important for cardiovascular disease prevention. The periodic identification and quantification of the food that most affects the dietary fat profile will help in drawing up dietary guidelines with more reasonable strategies for consuming a healthier diet and decreasing the risk of developing nutritional disorders.


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