Si-Rhodamine Derivatives for Brain Fluorescence Imaging and Monitoring of H2S in the Brain of Schizophrenic Mice before and after Treatment

2022 ◽  
Author(s):  
Yujie Geng ◽  
Guoyang Zhang ◽  
Yuzhi Chen ◽  
Yanghan Peng ◽  
Xuefei Wang ◽  
...  
Keyword(s):  
Fluorescence Imaging ◽  
Before And After ◽  
Rhodamine Derivatives ◽  
The Brain

PENGARUH PIJAT BAYI TERHADAP KUALITAS TIDUR BAYI UMUR 0 – 3 BULAN DI WILAYAH KERJA PUSKESMAS SOSIAL PALEMBANG TAHUN 2016

2019 ◽  
Vol 6 (2) ◽  
Author(s):  
Juliana Widyastuti Wahyuningsih Juliana Widyastuti Wahyuningsih
Keyword(s):  
Experimental Design ◽  
Growth And Development ◽  
Sampling Technique ◽  
P Value ◽  
Development Phase ◽  
Quality Of Sleep ◽  
Infant Massage ◽  
Before And After ◽  
The Brain

ABSTRAK Tidur merupakan kebutuhan yang harus terpenuhi terutama pada fase perkembangan karena selama tidur akan terjadi perkembangan otak maupun tubuh, sehingga gangguan tidur merupakan masalah yang akan menimbulkan dampak buruk terhadap pertumbuhan dan perkembangan bayi. Kualitas tidur bayi yang baik dapat diciptakan dengan memberikan pemijatan bayi secara rutin. Penelitian ini bertujuan untuk membuktikan bahwa pemijatan dapat mempengaruhi kualitas tidur bayi umur 0-3 bulan. Penelitian ini menggunakan desain penelitian Quasy Eksperimental dengan metode One Group Pretest-Postest. Sampel 22 bayi yang dipilih dengan tehnik Total Sampling yang di observasi sebelum dan sesudah diberikan pemijatan. Variabel yang diukur dalam penelitian ini adalah kualitas tidur bayi 0-3 bulan. Hasil penelitian menunjukkan bahwa ada pengaruh pijat bayi terhadap kualitas tidur bayi umur 0-3 bulan (p value  0,008 < α = 0,05).Berdasarkan hasil penelitian ini disarankan agar keluarga dan masyarakat memberikan pemijatan secara rutin dan mandiri untuk meningkatkan kebutuhan tidur bayi yang berkualitas.   ABSTRACT Sleep is a human necessity that must be met, especially in the development phase because during sleep will occur the brain and body developments, so that sleep disturbance is a problem that would cause adverse effects on infants’ growth and development. The good quality of sleep can be created by providing the infants massage routinely. This study aimed to prove that the massage could affect the quality of sleep on the 0-3 months old baby. This study used Quasy-experimental design with One Group Pretest-Posttest. The sample 22 infants selected by total sampling technique observed on before and after the massage. The variables measured in this study are the quality of sleep. The results of study indicate that there is an effect of infant massage to the sleep quality on 0-3 months old babies (p value 0,008 < α = 0,05).Based on the results of this study it recommended for the families and communities to provide infant massage regularly and independently to increase the quality of sleep on the baby.  

Sources of the Scalp-Recorded Amplitude-Modulation Following Response

2002 ◽  
Vol 13 (04) ◽  
pp. 188-204 ◽  
Author(s):  
Shigeyuki Kuwada ◽  
Julia S. Anderson ◽  
Ranjan Batra ◽  
Douglas C. Fitzpatrick ◽  
Natacha Teissier ◽  
...  
Keyword(s):  
Animal Model ◽  
Amplitude Modulation ◽  
Single Unit ◽  
Modulation Frequency ◽  
Multiple Sources ◽  
High Modulation ◽  
Before And After ◽  
Single Unit Recordings ◽  
Composite Response ◽  
The Brain

The scalp-recorded amplitude-modulation following response (AMFR)” is gaining recognition as an objective audiometric tool, but little is known about the neural sources that underlie this potential. We hypothesized, based on our human studies and single-unit recordings in animals, that the scalp-recorded AMFR reflects the interaction of multiple sources. We tested this hypothesis using an animal model, the unanesthetized rabbit. We compared AMFRs recorded from the surface of the brain at different locations and before and after the administration of agents likely to enhance or suppress neural generators. We also recorded AMFRs locally at several stations along the auditory neuraxis. We conclude that the surface-recorded AMFR is indeed a composite response from multiple brain generators. Although the response at any modulation frequency can reflect the activity of more than one generator, the AMFRs to low and high modulation frequencies appear to reflect a strong contribution from cortical and subcortical sources, respectively.

scholarly journals Using Brain-Breaks® as a Technology Tool to Increase Attitude towards Physical Activity among Students in Singapore

2021 ◽  
Vol 11 (6) ◽  
pp. 784
Author(s):  
Govindasamy Balasekaran ◽  
Ahmad Arif Bin Ibrahim ◽  
Ng Yew Cheo ◽  
Phua Kia Wang ◽  
Garry Kuan ◽  
...  
Keyword(s):  
Physical Activity ◽  
Mixed Model ◽  
School Curriculum ◽  
Control Group ◽  
School Students ◽  
Mixed Model Analysis ◽  
Before And After ◽  
Brain Breaks ◽  
Student's Attitudes ◽  
The Brain

The purpose of this study was to investigate the effects of classroom-based Brain Breaks® Physical Activity Solution in Southeast Asia Singaporean primary school students and their attitude towards physical activity (PA) over a ten-week intervention. A total of 113 participants (8–11 years old) were randomly assigned to either an experimental (EG) or a control group (CG), with six classes to each group; the Brain Breaks® group (EG: six classes) and the Control group (CG: six classes). All EG members participated in a Brain Breaks® video intervention (three–five min) during academic classes and the CG continued their lessons as per normal. The student’s attitudes towards PA in both research conditions were evaluated using the self–reported Attitudes toward Physical Activity Scale (APAS), applied before and after intervention. The effects of the intervention on APAS scores were analysed using a mixed model analysis of variance with Time as within-subject and Group as between-subject factors. The analysis revealed evidence in support of the positive effect of classroom video interventions such as Brain Breaks® on student’s attitudes toward benefits, importance, learning, self-efficacy, fun, fitness, and trying to do their personal best in PA. The Brain Breaks® intervention provided a positive significant impact on students in Singapore. This study also revealed that interactive technology tools implemented into the school curriculum benefit students in terms of health and education.

Intraventricular injection of antibodies to β1-integrins generates pressure gradients in the brain favoring hydrocephalus development in rats

2009 ◽  
Vol 297 (5) ◽  
pp. R1312-R1321 ◽  
Author(s):  
Gurjit Nagra ◽  
Lena Koh ◽  
Isabelle Aubert ◽  
Minhui Kim ◽  
Miles Johnston
Keyword(s):  
Fluid Pressure ◽  
Active Role ◽  
Intraventricular Injection ◽  
Pressure Gradients ◽  
Tissue Pressure ◽  
Before And After ◽  
The Matrix ◽  
System 2 ◽  
Periventricular Area ◽  
The Brain

In some tissues, the injection of antibodies to the β1-integrins leads to a reduction in interstitial fluid pressure, indicating an active role for the extracellular matrix in tissue pressure regulation. If perturbations of the matrix occur in the periventricular area of the brain, a comparable lowering of interstitial pressures may induce transparenchymal pressure gradients favoring ventricular expansion. To examine this concept, we measured periventricular (parenchymal) and ventricular pressures with a servo-null micropipette system (2-μm tip) in adult Wistar rats before and after anti-integrin antibodies or IgG/IgM isotype controls were injected into a lateral ventricle. In a second group, the animals were kept for 2 wk after similar injections and after euthanization, the brains were removed and assessed for hydrocephalus. In experiments in which antibodies to β1-integrins ( n = 10) but not isotype control IgG/IgM ( n = 7) were injected, we observed a decline in periventricular pressures relative to the preinjection values. Under similar circumstances, ventricular pressures were elevated ( n = 10) and were significantly greater than those in the periventricular interstitium. We estimated ventricular to periventricular pressure gradients of up to 4.3 cmH2O. In the chronic preparations, we observed enlarged ventricles in many of the animals that received injections of anti-integrin antibodies (21 of 29 animals; 72%) but not in any animal receiving the isotype controls. We conclude that modulation/disruption of β1-integrin-matrix interactions in the brain generates pressure gradients favoring ventricular expansion, suggesting a novel mechanism for hydrocephalus development.

Study of electrical conductivity of biologically active points on the skin before and after mental activity

Vestnik ◽  
2021 ◽  
pp. 190-195
Author(s):  
М.С. Кулбаева ◽  
А.Н. Курал ◽  
Л.Б. Умбетьярова ◽  
Н.Т. Аблайханова ◽  
Г.К. Атанбаева ◽  
...  
Keyword(s):  
Physiological State ◽  
Mental Activity ◽  
The Body ◽  
Biologically Active ◽  
Mental Work ◽  
Heart Meridian ◽  
Before And After ◽  
Specific Organ ◽  
The Brain ◽  
Biologically Active Points

Человека давно интересует вопрос о том, как умственная нагрузка влияет на организм. Известно, что при длительной умственной работе преобразуется сила процессов возбуждения и торможения, изменяется соотношение между ними. С возникновением утомления в головном мозгу нарушаются взаимосвязи между корой больших полушарий и подкорковыми образованиями. При этом наблюдается снижение регулирующего влияния больших полушарий на все функции организма и уменьшение активизирующих воздействий подкорковых отделов мозга. Кроме того, длительное сидячие положение, состояние низкой двигательной активности ведут к значительному уменьшению центростремительных импульсов с рецепторов мышц, сухожилий, суставов. В исследовании приняли участие 17 относительно здоровые, имеющие стабильное физиологическое состояние девушек-студенток в возрасте от 21 до 25 лет. Для исследования были взяты 16 биологически активных точек на стандартных меридианах, связаных с определенным органом. Для оценки физиологического состояния органов до и после умственной нагрузки были исследованы показатели ЭП БАТ на коже. Выявлено снижение показателей каждого органа после умственной нагрузки по сравнению с показателями до ее выполнения со статистической достоверностью во всех исследуемых органах (р<0,05). Особенно низкие значения показателей ЭП БАТ после умственной нагрузки были выявлены в биоактивных точках меридиана печени F.3 Тай-Чун, меридиана толстой кишки GI.5 Ян-Си и GI.4 Хэ-Гу, меридиана сердца С.7 Шэнь-Мэнь, меридиана тонкой кишки IG.1 Шао-Цзе и IG.2 Цянь-Гу, меридиана почек R.1 Юн-Цюань и Р.2 Жань-Гу. Humans has long been interested in the question of how mental activity affects the body It is known that with prolonged mental work, the strength of the processes of excitation and inhibition is transformed, the ratio between them changes. With the onset of fatigue in the brain, the relationship between the cerebral cortex and subcortical formations is disrupted. At the same time, there is a decrease in the regulatory influence of the large hemispheres on all body functions and a decrease in the activating effects of the subcortical parts of the brain. In addition, prolonged sitting, a state of low motor activity leads to a significant decrease in centripetal impulses from the receptors of muscles, tendons, and joints. The study involved 17 relatively healthy, stable physiological condition of female students aged 21 to 25 years. For the study, 16 biologically active points were taken from standard meridians associated with a specific organ. To assess the physiological state of the organs before and after the load of mental labor, the indicators of EC BAP on the skin. A decrease in the indicators of each organ after mental labor was revealed in comparison with the indicators before mental labor with statistical reliability in all the studied organs (p˂0.05). Especially low values of the EC BAP values after a load of mental labor were found in the bioactive points of the liver meridian F. 3 Tai-Chun, the colon meridian GI.5 Yang-Si and GI. 4 He-Gu, the heart meridian C. 7 Shen-Men, the small intestine meridian IG.1 Shao-tse and IG.2 Qian-Gu, the meridian of the kidneys R. 1 Yun-Chuan and R. 2 Zhan-Gu.

A bimodal probe for fluorescence and synchrotron X-ray fluorescence imaging of dopaminergic neurons in brain

2022 ◽  
Author(s):  
Meiling Yan ◽  
Tingting Zuo ◽  
Jichao Zhang ◽  
Yiyang Wang ◽  
Ying Zhu ◽  
...  
Keyword(s):  
Fluorescence Imaging ◽  
Immunoglobulin G ◽  
Dopaminergic Neurons ◽  
X Ray ◽  
Erythrosine B ◽  
The Brain

A bimodal probe, erythrosine B (EB) conjugated immunoglobulin G complex (EB/IgG), has been developed for fluorescence and synchrotron X-ray fluorescence (SXRF) imaging of dopaminergic neurons in the brain.

scholarly journals Perfusion Imaging of the Brain Using Z-Score and Dynamic Images Obtained by Subtracting Images from before and after Contrast Injection

2004 ◽  
Vol 5 (3) ◽  
pp. 143 ◽  
Author(s):  
Sunseob Choi ◽  
Haiying Liu ◽  
Tae Beom Shin ◽  
Jin Hwa Lee ◽  
Seong Kuk Yoon ◽  
...  
Keyword(s):  
Perfusion Imaging ◽  
Z Score ◽  
Contrast Injection ◽  
Before And After ◽  
The Brain

scholarly journals Brain Function Assessment of Patients with Multiple Sclerosis in the Expanded Disability Status Scale

2020 ◽  
Vol 22 (1) ◽  
pp. 31-35
Author(s):  
Ricardo N. Alonso ◽  
Maria B. Eizaguirre ◽  
Berenice Silva ◽  
Maria C. Pita ◽  
Cecilia Yastremiz ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Brain Function ◽  
Cognitive Assessment ◽  
Functional System ◽  
Expanded Disability Status Scale ◽  
Disability Status ◽  
Before And After ◽  
Survey Results ◽  
Edss Score ◽  
The Brain

Abstract Background: There is no consensus regarding assessment of the brain function functional system (FS) of the Expanded Disability Status Scale (EDSS) in patients with multiple sclerosis (MS). We sought to describe brain function FS assessment criteria used by Argentinian neurologists and, based on the results, propose redefined brain function FS criteria. Methods: A structured survey was conducted of 113 Argentinian neurologists. Considering the survey results, we decided to redefine the brain function FS scoring using the Brief International Cognitive Assessment for MS (BICAMS) battery. For 120 adult patients with MS we calculated the EDSS score without brain function FS (basal EDSS) and compared it with the EDSS score after adding the modified brain function FS (modified EDSS). Results: Of the 93 neurologists analyzed, 14% reported that they did not assess brain function FS, 35% reported that they assessed it through a nonstructured interview, and the remainder used other tools. Significant differences were found in EDSS scores before and after the inclusion of BICAMS (P &lt; .001). Redefining the brain function FS, 15% of patients modified their basal EDSS score, as did 20% of those with a score of 4.0 or less. Conclusions: The survey results show the importance of unifying the brain function FS scoring criteria in calculating the EDSS score. While allowing more consistent brain function FS scoring, including the modified brain function FS led to a change in EDSS score in many patients, particularly in the lower range of EDSS scores. Considering the relevance of the EDSS for monitoring patients with MS and for decision making, it is imperative to further validate the modified brain function FS scoring.

scholarly journals PENGARUH PEMBERIAN OKSIGEN DAN ELEVASI KEPALA 30º TERHADAP TINGKAT KESADARAN PADA PASIEN CEDERA KEPALA SEDANG

2020 ◽  
Vol 2 (2) ◽  
pp. 102-112
Author(s):  
Luci Riani Ginting ◽  
Kuat Sitepu ◽  
Renni Ariana Ginting
Keyword(s):  
Head Injury ◽  
Skull Fracture ◽  
P Value ◽  
Average Value ◽  
Level Of Consciousness ◽  
Before And After ◽  
Quasi Experimental ◽  
Oxygen Perfusion ◽  
The Brain ◽  
Adequate Oxygenation

Head injury is directly or indirectly mechanical injuries that resulted wound in the scalp, skull fracture, tear the lining of the brain, and brain damage, and neurological disorders. The basic method for brain protection of head injury patients are freeing the airway and giving adequate oxygenation. Giving oxygen and headv elevation 30° of head are the appropriate action for the moderate head injury classification to launch the cerebral oxygen perfusion and to increase consciousness level. The purpose of this research were to determine the GCS before and after giving oxygenation with and position 30 ° of head and to analyze the effect of giving oxygen and headv elevation30 °of head to change the levels of consciousness of moderate head injury patients. This research was an Quasi-Experimental study with 10 respondents. The test were used Paired Sample T-test Test. The results showed that there was an effect of giving oxygen and headv elevation 30 °of head toward to change the level of consciousness of moderate head injury patients. GCS average value before was 10.10 and GCS average after 12.90 value was with p value was 0.000. Keywords : Levels of Consciousness GCS, Moderate Head Injury, Position 30° of the Head

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