scholarly journals Human, animal, water source interactions and leptospirosis in Thailand

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Udomsak Narkkul ◽  
Janjira Thaipadungpanit ◽  
Nattachai Srisawat ◽  
James W. Rudge ◽  
Metawee Thongdee ◽  
...  
Keyword(s):  
High Risk ◽  
Water Source ◽  
Environmental Water ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Contact Patterns ◽  
Spatial Environment ◽  
Animal Contact ◽  
Risk Areas ◽  
Human Animal

AbstractIn Thailand, leptospirosis is primarily associated with those who work in agricultural occupations. Leptospirosis control is hampered by a poor understanding of the complex interactions between humans, animal reservoirs, Leptospira, and the variable spatial environment in which these factors coexist. We aimed to address key knowledge gaps concerning leptospirosis disease dynamics and the human–animal–water-source interface in two high-risk areas in Thailand. We conducted a cross-sectional survey among 746 study participants in two high-risk areas for leptospirosis in Thailand: Sisaket (SSK) and Nakhon Si Thammarat (NST). Interactions among humans, animals and water sources were quantified and analyzed. The presence of different animal species and thus contact patterns were different in NST and SSK. The consumption of water from the shared sources between the two areas was different. Those whose occupations were related to animals or environmental water and those who consumed water from more than two sources were more likely to have been infected with leptospirosis, with adjusted odds ratios 4.31 (95% CI 1.17–15.83) and 10.74 (95% CI 2.28–50.53), respectively. Understanding specific water-source sharing networks and human–animal contact patterns is useful when designing national and area-specific control programmes to prevent and control leptospirosis outbreaks.

scholarly journals Spatio-temporal epidemiology of the tuberculosis incidence rate in Iran 2008 to 2018

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Behzad Kiani ◽  
Amene Raouf Rahmati ◽  
Robert Bergquist ◽  
Soheil Hashtarkhani ◽  
Neda Firouraghi ◽  
...  
Keyword(s):  
High Risk ◽  
Incidence Rate ◽  
Policy Development ◽  
Temporal Pattern ◽  
Temporal Analysis ◽  
High Rate ◽  
Spatial Scan Statistic ◽  
Cross Sectional ◽  
Risk Areas ◽  
Spatio Temporal

Abstract Background Effective reduction of tuberculosis (TB) requires information on the distribution of TB incidence rate across time and location. This study aims to identify the spatio-temporal pattern of TB incidence rate in Iran between 2008 and 2018. Methods This cross-sectional study was conducted on aggregated TB data (50,500 patients) at the provincial level provided by the Ministry of Health in Iran between 2008 and 2018. The Anselin Local Moran’s I and Getis-Ord Gi* were performed to identify the spatial variations of the disease. Furthermore, spatial scan statistic was employed for purely temporal and spatio-temporal analyses. In all instances, the null hypothesis of no clusters was rejected at p ≤ 0.05. Results The overall incidence rate of TB decreased from 13.46 per 100,000 (95% CI: 13.19–13.73) in 2008 to 10.88 per 100,000 (95% CI: 10.65–11.11) in 2018. The highest incidence rate of TB was observed in southeast and northeast of Iran for the whole study period. Additionally, spatial cluster analysis discovered Khuzestan Province, in the West of the country, having significantly higher rates than neighbouring provinces in terms of both total TB and smear-positive pulmonary TB (SPPTB). Purely temporal analysis showed that high-rate and low-rate clusters were predominantly distributed in the time periods 2010–2014 and 2017–2018. Spatio-temporal results showed that the statistically significant clusters were mainly distributed from centre to the east during the study period. Some high-trend TB and SPPTB statistically significant clusters were found. Conclusion The results provided an overview of the latest TB spatio-temporal status In Iran and identified decreasing trends of TB in the 2008–2018 period. Despite the decreasing incidence rate, there is still need for screening, and targeting of preventive interventions, especially in high-risk areas. Knowledge of the spatio-temporal pattern of TB can be useful for policy development as the information regarding the high-risk areas would contribute to the selection of areas needed to be targeted for the expansion of health facilities.

scholarly journals Spatial Distribution of Breast Cancer in Sudan 2010-2016

2019 ◽  
Author(s):  
Marwa Maweya Abdelbagi Elbasheer ◽  
Ayah Galal Abdelrahman Alkhidir ◽  
Siham Mohammed Awad Mohammed ◽  
Areej Abuelgasim Hassan Abbas ◽  
Aisha Osman Mohamed ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Spatial Distribution ◽  
Spatial Analysis ◽  
High Risk ◽  
Geographical Information ◽  
Risk Level ◽  
Histopathological Diagnosis ◽  
Cross Sectional ◽  
Distribution Maps ◽  
Risk Areas

AbstractBackgroundBreast cancer is the most prevalent cancer among females worldwide including Sudan. The aim of this study was to determine the spatial distribution of breast cancer in Sudan.Materials and methodsA facility based cross-sectional study was implemented in eighteen histopathology laboratories distributed in the three localities of Khartoum State on a sample of 4630 Breast Cancer cases diagnosed during the period 2010-2016. A master database was developed through Epi Info™ 7.1.5.2 for computerizing the data collected: the facility name, type (public or private), and its geo- location (latitude and longitude). Personal data on patients were extracted from their respective medical records (name, age, marital status, ethnic group, State, locality, administrative unit, permanent address and phone number, histopathology diagnosis). The data was summarized through SPSS to generate frequency tables for estimating prevalence and the geographical information system (ArcGIS 10.3) was used to generate the epidemiological distribution maps. ArcGIS 10.3 spatial analysis features were used to develop risk maps based on the kriging method.ResultsBreast cancer prevalence was 3.9 cases per 100,000 female populations. Of the 4423 cases of breast cancer, invasive breast carcinoma of no special type (NST) was the most frequent (79.5%, 3517/4423) histopathological diagnosis. The spatial analysis indicated as high risk areas for breast cancer in Sudan the States of Nile River, Northern, Red Sea, White Nile, Northern and Southern Kordofan.ConclusionsThe attempt to develop a predictive map of breast cancer in Sudan revealed three levels of risk areas (risk, intermediate and high risk areas); regardless the risk level, appropriate preventive and curative health interventions with full support from decision makers are urgently needed.

scholarly journals Spatial-time Visualization of Cutaneous Leishmaniasis in an Urban Area: Informing Health Policy and Practice

2020 ◽  
Author(s):  
Neda Firouraghi ◽  
Sayyed Mostafa Mostafavi ◽  
Amene Raouf-Rahmati ◽  
Alireza Mohammadi ◽  
Reza Saemi ◽  
...  
Keyword(s):  
High Risk ◽  
Incidence Rate ◽  
Urban Area ◽  
Incidence Rates ◽  
Low Risk ◽  
Health Concern ◽  
Surveillance Systems ◽  
Cross Sectional ◽  
Targeted Interventions ◽  
Risk Areas

Abstract Background:Cutaneous leishmaniasis (CL) is an important public health concern worldwide. Iran is among the most CL-affected countries, being listed as one of the first six endemic countries in the world. In order to develop targeted interventions, we performed a spatial-time visualization of CL cases in an urban area to identify high-risk and low-risk areas during 2016-2019.Methods:This cross-sectional study was conducted in the city of Mashhad. Patient data were gathered from Mashhad health centers. All cases (n=2425) were diagnosed in two stages; the initial diagnosis was based on clinical findings. Subsequently, clinical manifestation was confirmed by parasitological tests. The data were aggregated at the neighborhood and district levels and smoothed CL incidence rates per 100,000 individuals were calculated using the spatial empirical Bayesian approach. Furthermore, we used the Anselin Local Moran’s I statistic to identify clusters and outliers of CL distribution during 2016-2019 in Mashhad. Results:The overall incidence rates decreased from 34.6 per 100,000 in 2016 to 19.9 per 100,000 individuals in 2019. Both cluster analyses by crude incidence rate and smoothed incidence rate identified high-risk areas in southwestern Mashhad over the study period. Furthermore, the analyses revealed low-risk areas in northeastern Mashhad over the same 3-year period.Conclusions:The southwestern area of Mashhad had the highest CL incidence rates. This piece of information might be of value to design tailored interventions such as running effective resource allocation models, informed control plans and implementation of efficient surveillance systems. Furthermore, this study generates new hypotheses to test potential relationships between socio-economic and environmental risk factors and incidence of CL in areas with higher associated risks.

scholarly journals Epidemiology of Thalassemia in Gulf Cooperation Council Countries: A Systematic Review

2020 ◽  
Vol 2020 ◽  
pp. 1-15
Author(s):  
Amani Abu-Shaheen ◽  
Humariya Heena ◽  
Abdullah Nofal ◽  
Doaa A. Abdelmoety ◽  
Abdulrahman Almatary ◽  
...  
Keyword(s):  
Systematic Review ◽  
High Risk ◽  
United Arab Emirates ◽  
Observational Studies ◽  
Gulf Cooperation Council ◽  
Cross Sectional ◽  
Gcc Countries ◽  
Premarital Screening ◽  
Risk Areas ◽  
Epidemiological Profile

Background. Thalassemia has a burden on the healthcare systems of many countries. About 56000 conceptions result in thalassemia, globally. Objective. To assess the epidemiological profile of thalassemia in the Gulf Cooperation Council (GCC) countries. Methods. A systematic search was conducted in MEDLINE/PubMed (National Library of Medicine), CINAHL, and Embase. Relevant observational studies reporting the epidemiology of thalassemia among the GCC population were selected. Data on the prevalence, frequency, and complications of thalassemia were extracted. The quality of the retrieved studies was assessed according to the Newcastle–Ottawa Quality Assessment Scale. Results. Eighteen studies (14 cross-sectional studies, two retrospective observational studies, and two retrospective analysis) with a total of 3343042 participants were included in this systematic review. Of the 18 studies, 11 studies were conducted in Saudi Arabia, two in the Kingdom of Bahrain, one in Kuwait, three in the United Arab Emirates (UAE), and one in Qatar. The prevalence of thalassemia among children below five years of age ranged from 0.25% to 33%, while it was 0.9% in children above five years and from 0.035% to 43.3% among adult thalassemia patients. The most-reported risk factors were consanguineous marriage and high-risk marriage. There was a lack of data regarding mortality rates in thalassemia. Conclusions. Despite the premarital screening and genetic counseling (PMSGC) program for thalassemia, the incidence of high-risk couple marriages in GCC countries cannot be effectively diminished. This study suggested that the PMSGC program should adopt more attention for the high-risk areas, to enhance the level of consciousness about the hemoglobinopathy diseases and the consequences of consanguinity among the at-risk couple.

Venous thromboembolism in medical outpatients – a cross-sectional survey of risk assessment and prophylaxis

2011 ◽  
Vol 105 (01) ◽  
pp. 190-196 ◽  
Author(s):  
Holger Lawall ◽  
Andreas Matthiessen ◽  
Volker Hohmann ◽  
Peter Bramlage ◽  
Sylvia Haas ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Venous Thromboembolism ◽  
High Risk ◽  
Medical Condition ◽  
Assessment Tools ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Limited Mobility ◽  
Substantial Risk ◽  
Medical Outpatients

SummaryThe degree of thromboprophylaxis in medical outpatients is low despite a substantial risk for venous thromboembolism (VTE). This may be attributable to difficulties in assessing risk. Assessment tools like the Haas’ scorecard aid in determining the need for thromboprophylaxis. We aimed at evaluating how the use of this tool may aid physicians in appropriately using anticoagulants. This was an epidemiological, cross-sectional survey of acute medically ill patients with limited mobility treated by general practitioners and internists. Risk assessment for VTE by the treating physician was compared to calculated risk. Of 8,123 patients evaluated between August 2006 and April 2008, 7,271 fulfilled the in- and exclusion criteria. Mean age was 69.4 ± 13.6 years, and 45.2% were male. Of these 82.8% were high risk based on their acute medical condition, 37.9% based on their underlying chronic condition. Immobilisation, heart failure, pneumonia, age, obesity, and major varicosis were the most frequently encountered risk factors. The agreement between the Haas’ scorecard and physician indicated risk was high. At least 94.1% of patients with high risk received adequate anticoagulation mostly as low molecular weight heparins for a mean duration of 15.1 ± 30.5 days. There is a substantial risk for VTE in medical out-patients. Using a simple structured scorecard resulted in an overall appropriate risk assessment and high degree of anticoagulation. The scorecard may provide a tool to improve the overall awareness for VTE risk in medical outpatients, substantially improving the degree of prophylaxis in a patient population with largely underestimated risk.

scholarly journals The prevalence of noma in northwest Nigeria

2020 ◽  
Vol 5 (4) ◽  
pp. e002141
Author(s):  
Elise Farley ◽  
Modupe Juliana Oyemakinde ◽  
Jorien Schuurmans ◽  
Cono Ariti ◽  
Fatima Saleh ◽  
...  
Keyword(s):  
Neglected Tropical Diseases ◽  
Multivariable Analysis ◽  
Water Source ◽  
Drinking Water Source ◽  
Age Group ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Factors Associated ◽  
High Prevalence ◽  
Oral Screening

BackgroundNoma, a rapidly progressing infection of the oral cavity, mainly affects children. The true burden is unknown. This study reports estimated noma prevalence in children in northwest Nigeria.MethodsOral screening was performed on all ≤15 year olds, with caretaker consent, in selected households during this cross-sectional survey. Noma stages were classified using WHO criteria and caretakers answered survey questions. The prevalence of noma was estimated stratified by age group (0–5 and 6–15 years). Factors associated with noma were estimated using logistic regression.ResultsA total of 177 clusters, 3499 households and 7122 children were included. In this sample, 4239 (59.8%) were 0–5 years and 3692 (52.1%) were female. Simple gingivitis was identified in 3.1% (n=181; 95% CI 2.6 to 3.8), acute necrotising gingivitis in 0.1% (n=10; CI 0.1 to 0.3) and oedema in 0.05% (n=3; CI 0.02 to 0.2). No cases of late-stage noma were detected. Multivariable analysis in the group aged 0–5 years showed having a well as the drinking water source (adjusted odds ratio (aOR) 2.1; CI 1.2 to 3.6) and being aged 3–5 years (aOR 3.9; CI 2.1 to 7.8) was associated with being a noma case. In 6–15 year olds, being male (aOR 1.5; CI 1.0 to 2.2) was associated with being a noma case and preparing pap once or more per week (aOR 0.4; CI 0.2 to 0.8) was associated with not having noma. We estimated that 129120 (CI 105294 to 1 52 947) individuals <15 years of age would have any stage of noma at the time of the survey within the two states. Most of these cases (93%; n=120 082) would be children with simple gingivitis.ConclusionsOur study identified a high prevalence of children at risk of developing advanced noma. This disease is important but neglected and therefore merits inclusion in the WHO neglected tropical diseases list.

scholarly journals The Risk of Sexually Transmitted Infection and Its Influence on Condom Use among Pregnant Women in the Kintampo North Municipality of Ghana

2017 ◽  
Vol 2017 ◽  
pp. 1-12 ◽  
Author(s):  
Martha Ali Abdulai ◽  
Frank Baiden ◽  
Samuel Afari-Asiedu ◽  
Lawrence Gyabaa-Febir ◽  
Kwame Kesse Adjei ◽  
...  
Keyword(s):  
High Risk ◽  
Condom Use ◽  
Pregnant Women ◽  
Sexually Transmitted Infection ◽  
Secondary Analysis ◽  
Multivariate Logistic Regression Analysis ◽  
Cross Sectional Survey ◽  
Transmitted Infection ◽  
Cross Sectional ◽  
Sexually Transmitted

Sexually transmitted infection (STI) affects the reproductive health of both men and women worldwide. Condoms are important part of the available preventive strategies for STI control. The lack of proper risk-perception continues to impede women’s ability to negotiate condom use with their partners. This paper is the outcome of secondary analysis of data collected in a cross-sectional survey that explored the perception of risk of STI and its influence on condom use among 504 pregnant women attending antenatal clinic at two health facilities in the Kintampo North Municipality. Consecutively, three Focus Group Discussions were conducted among 22 pregnant women which was analyzed using thematic analysis technique. Multivariate logistic regression analysis was used to identify possible predictors of condom use and risk of STI. Respondents mean age was 26.0±5.9 years. 47% of respondents self-identified themselves as high risk for contracting STI, 50% of whom were married. High risk status (OR = 2.1, 95% CI: 1.1–4.4), ability to ask for condoms during sex (OR = 0.3, 95% CI: 0.1–0.73), and partner’s approval of condom use (OR = 0.2, 95% CI: 0.01–0.05) were independent predictors of condom use. Condom use (OR 2.9 (1.5–5.7); p=0.001) and marital status (engaged, OR 2.6 (1.5–4.5); p=0.001) were independent predictors of risk of STI. Women who self-identified themselves as high risk for STI successfully negotiated condom use with their partners. This is however influenced by partner’s approval and ability to convince partner to use condoms. Self-assessment of STI risk by women and the cooperation of male partners remain critical.

scholarly journals Malaria in pregnancy in rural Gabon: a cross-sectional survey on the impact of seasonality in high-risk groups

2013 ◽  
Vol 12 (1) ◽  
pp. 412 ◽  
Author(s):  
Mario J Jäckle ◽  
Christian G Blumentrath ◽  
Rella M Zoleko ◽  
Daisy Akerey-Diop ◽  
Jean-Rodolphe Mackanga ◽  
...  
Keyword(s):  
High Risk ◽  
Risk Groups ◽  
Malaria In Pregnancy ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
The Impact ◽  
In Pregnancy

scholarly journals Prevalence of stroke and stroke related risk factors: a population based cross sectional survey in southwestern China

2019 ◽  
Author(s):  
Xingyang Yi ◽  
Hua Luo ◽  
Ju Zhou ◽  
Ming Yu ◽  
Xiaorong Chen ◽  
...  
Keyword(s):  
Risk Factors ◽  
Family History ◽  
High Risk ◽  
Population Attributable Risk ◽  
Southwestern China ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Stroke Population ◽  
History Of ◽  
Lack Of Exercise

Abstract Background: Stroke and its risk factors epidemiological survey can help identify individuals at higher risk and therefore promote stroke prevention strategies. The aim of this study was to estimate the current prevalence of stroke and high risk stroke population, and evaluate stroke associated risk factors in southwestern China. Methods: This was a multi-center, cross sectional survey in southwestern China from May 2015 to September 2015. The 8 communities were selected at random, and 17413 residents aged ≥ 40 years volunteered to participate in this survey. Data were collected through face-to-face survey using a structured questionnaire. 521 participants with incomplete questionnaires on stroke history or risk factors records were excluded. Results: A total of 16892 people included in analysis. The overall prevalence of stroke was 3.1% (95% CI 2.6% - 3.9%), 17.1% of participants were the high risk stroke population. After full adjustments, hypertension, diabetes, dyslipidemia, overweight, lack of exercise and family history of stroke were significantly associated with overall stroke and ischemic stroke. The largest contributor was hypertension (population-attributable risk 23.6%), followed by dyslipidemia, physical inactivity, family history of stroke, diabetes, and overweight. However, only hypertension (OR = 3.66, 95% CI 1.82-8.23) was significantly associated with hemorrhagic stroke. Conclusions: The prevalence of stroke and high risk stroke population was high among adults aged ≥ 40 years in southwestern China. Hypertension, dyslipidemia and lack of exercise were stronger contributors for stroke, these findings suggest that individual-level and population-level interventions for these leading risk factors are necessary to prevent stroke.

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