scholarly journals The characteristics and risk factors of human papillomavirus infection: an outpatient population-based study in Changsha, Hunan

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Bingsi Gao ◽  
Yu-Ligh Liou ◽  
Yang Yu ◽  
Lingxiao Zou ◽  
Waixing Li ◽  
...  

AbstractThis cross-sectional study investigated the characteristics of cervical HPV infection in Changsha area and explored the influence of Candida vaginitis on this infection. From 11 August 2017 to 11 September 2018, 12,628 outpatient participants ranged from 19 to 84 years old were enrolled and analyzed. HPV DNA was amplified and tested by HPV GenoArray Test Kit. The vaginal ecology was detected by microscopic and biochemistry examinations. The diagnosis of Candida vaginitis was based on microscopic examination (spores, and/or hypha) and biochemical testing (galactosidase) for vaginal discharge by experts. Statistical analyses were performed using SAS 9.4. Continuous and categorical variables were analyzed by t-tests and by Chi-square tests, respectively. HPV infection risk factors were analyzed using multivariate logistic regression. Of the total number of participants, 1753 were infected with HPV (13.88%). Females aged ≥ 40 to < 50 years constituted the largest population of HPV-infected females (31.26%). The top 5 HPV subtypes affecting this population of 1753 infected females were the following: HPV-52 (28.01%), HPV-58 (14.83%), CP8304 (11.47%), HPV-53 (10.84%), and HPV-39 (9.64%). Age (OR 1.01; 95% CI 1–1.01; P < 0.05) and alcohol consumption (OR 1.30; 95% CI 1.09–1.56; P < 0.01) were found to be risk factors for HPV infection. However, the presence of Candida in the vaginal flora was found to be a protective factor against HPV infection (OR 0.62; 95% CI 0.48–0.8; P < 0.001). Comparing with our previous study of 2016, we conclude that the subtype distribution of HPV infection is relatively constant in Changsha. Our data suggest a negative correlation between vaginal Candida and HPV, however, more radical HPV management is required in this area for perimenopausal women and those who regularly consume alcohol.

Author(s):  
Karol Fireman de Farias ◽  
Adrielle Sonara Gomes Silva ◽  
Ana Caroline Melo dos Santos ◽  
Adriely Ferreira da Silva ◽  
Denise Macedo da Silva ◽  
...  

Objective: This study sought to identify the presence of HPV infection and the risk factors related to susceptibility to cervical cancer in asymptomatic women. Methods: It is a cross-sectional study with 428 users attended Basic Health Units, in Arapiraca, Alagoas, Brazil. Sociodemographic, behavioral variables, and cytopathological reports were collected. Molecular detection of the HPV virus was performed by Nested-PCR. Statistical analysis was conducted with SPSS version 22.0. Results: A total of 428 women were studied, HPV DNA detected in 39.2% (n = 168), with a mean age of 41 years old. There was an association of HPV with use of oral contraceptives (p <0.016) and alcoholism (p <0.038). It was showed a higher frequency of positive HPV in women older than 25 years old (88.7%), up to 5 sexual partners (93.4%), up to 3 pregnancies (71.4%), and with the cytopathologic results within the limits of normality (61.9%). HPV was identified in 40.3% (104/258) of the women with results within the limits of normality. Conclusion: Our results suggest that the use of oral contraceptives and alcoholism may be considered as possible risk factors related to cervical oncogenesis. With this, it is necessary to propose interventions aimed at the health education of this population, actions of prevention, and early detection.


2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Mostafa Bijani ◽  
Saeed Parvizi ◽  
Azizallah Dehghan ◽  
Massih Sedigh-Rahimabadi ◽  
Mahsa Rostami-chijan ◽  
...  

Abstract Background A high prevalence rate of hypertension (HTN) and its subsequent serious complications made this disease a major health-treatment concern in many societies. The current study aimed to investigate the prevalence of hypertension and its associated risk factors in Fasa PERSIAN COHORT in south of Iran in 2019. Methods This was an analytical-cross sectional study. The study population were the individuals covered by Fasa cohort. Information of the first phase of Fasa Persian cohort in south of Iran was used in this study. Independent t test, chi-square test, analysis of variances, Pearson correlation coefficient, and multiple stepwise regression were used to analyze the obtained data. Thereafter, the data was analyzed using SPSS software version 22, and P value < 0.05 was considered as statistically significant. Results Out of 10,111 individuals included in the study, 5546 (54.86%) subjects were women and 4565 (45.16%) other were men. The overall prevalence rate of hypertension was estimated as 46.6%. In the present study, (16/1%) of the participants were with HTN stage 1, and (17/9%) of them were with HTN stage 2. The results show that there were significant positive correlations among HTN and age, BMI, HDL, TG, BUN, ALP, smoking, physical activity, cardiovascular diseases, diabetes, and renal failure (P < 0.5). Conclusions Prevalence of HTN in this study population is considerable. Therefore, it is suggested that health system should program some plans to prevent hypertension’s prevalence and eliminate its risk factors.


Author(s):  
Bahni Chakraborty ◽  
Pushpita Chakraborty ◽  
Ashekul Islam ◽  
M. Nur Hossain Bhuiyan ◽  
Pulak Kanti Palit ◽  
...  

<p><strong>Background:</strong> Bangladesh police have been engaged in different COVID-19 related containment activities consequently they are being badly affected and sacrifice their lives. However, as a newly outbreak pandemic, there may have lack of proper knowledge, attitude and practices in handling to prevent rapid spreading of deadly COVID-19 virus in Bangladesh.</p><p><strong>Methods:</strong> This cross-sectional study was conducted to assess the KAP and associated risk factors with COVID-19 among police personnel during pandemic. Total 2290 police personnel from different metropolitan cities were included and data were collected over telephone interview with an administered questionnaire following a convenient sampling technique. Bivariate associations between categorical variables were examined using Chi-square test. We also explored the independent risk factors for COVID-19 infection using binary logistic regression.</p><p><strong>Results: </strong>Out of 2290 respondents 458 (20%) were found to be COVID-19 positive and majority (42.5%) of them were male (97.5%) and belonged to age group of 31-40 years. Our study showed that an increased risk of COVID-19 infection for those who stayed in police barrack (OR=3.45; 95% CI:1.21-6.42; p&lt;0.021), not practicing social distancing always (OR=2.13; 95% CI:1.12-5.31; p&lt;0.031) and not wearing mask appropriately (OR=2.15; 95% CI: 1.31-4.52; p&lt;0.003). <strong></strong></p><p><strong>Conclusions:</strong> This study provides a unique baseline of KAP and professional risk factors among the police personnel in Bangladesh on COVID-19 which indicated that, community-based health campaigns are obligatory to hold expectant attitudes and practice appropriate intervention measures. KAP study aimed at other front liners should be urgently addressed.</p>


2020 ◽  
Author(s):  
Mostafa Bijani ◽  
Saeed Parvizi ◽  
Azizallah Dehghan ◽  
Massih Sedigh Rahimabadi ◽  
Mahsa Rostami Chijan ◽  
...  

Abstract Background: High prevalence of hypertension (HTN) and its subsequent serious complications make this disease as a major health-treatment concern in many societies. The current study aimed to investigate known factors as risk factors for hypertension and the way of their association in study population of Fasa cohort in south of Iran at 2019.Methods: This is an analytical-cross sectional study. Study population was the individuals covered by Fasa cohort. Information of the first phase of Fasa Persian cohort in south of Iran was used in the study. Independent t-test, chi-square test, analysis of variances, Pearson correlation coefficient, and logistic regression were used to analyze data. Data was analyzed using SPSS software version 22, and P-value<0.05 was considered statistically significant.Results: Out of the population of 10111 individuals of the study, 5546(54.86%) subjects were female and 4565(45.16%) were male. The overall prevalence of hypertension was 41.8 %. In the present study (28/5%) were with HTN stage 1, and (13/3%), were with HTN stage 2. In addition, a significant association was observed among HTN and cardiovascular diseases, diabetes and renal failure (p<0.5).Conclusions: prevalence of HTN in study population is considerable. Given its hazardous complications, application of appropriate methods in order to screen, prevent and treat HTN is necessary. In addition, using training programs, changing lifestyle, and promoting self-care behaviors can be effective in prevention, control, and decrease in hazardous complications caused by HTN.


2016 ◽  
Vol 5 (3) ◽  
Author(s):  
Siqbal Karta Asmana ◽  
Syahredi Syahredi ◽  
Noza Hilbertina

AbstrakPreeklampsia dapat menimbulkan berbagai komplikasi yang membahayakan bagi ibu dan janin, sehingga dapat menimbulkan kematian.  Beberapa faktor risiko seperti usia yang ekstrem (<20 &>35 tahun) dan nuliparitas. Keduanya merupakan faktor risiko yang tidak dapat dimodifikasi. Tujuan  penelitian ini adalah menentukan hubungan usia dan paritas dengan kejadian preeklampsia berat. Telah dilakukan penelitian di Bagian Rekam Medis Rumah Sakit Achmad Mochtar Bukittinggi terhadap data semua pasien rawat inap obstetri dan ginekologi tahun 2012 – 2013.  Penelitian menggunakan metode analitik dengan desain cross sectional study. Analisis penelitian menggunakan ratio prevalence dan chi-square test dengan derajat kepercayaan 95%. Penelitian ini menemukan 162 kasus (4,99%) preeklampsia berat. Proporsi kasus terbesar ditemukan pada kelompok usia ekstrem (9,90%) dan kelompok multiparitas (8,68%). Analisis ratio prevalence menyimpulkan bahwa usia ekstrem merupakan faktor risiko preeklampsia berat (RP= 1,476; CI= 1,094 – 1,922), dan nuliparitas belum dapat ditentukan apakah merupakan faktor risiko atau faktor protektif (RP= 0,765; CI= 0,565 – 1,034). Berdasarkan analisis dengan chi-square test, disimpulkan bahwa terdapat hubungan yang bermakna antara usia dengan preeklampsia berat (p= 0,014<0,05) dan tidak terdapat hubungan yang bermakna antara paritas dengan preeklampsia berat (p= 0,096>0,05).Kata kunci: preeklampsia, faktor risiko, usia, paritas AbstractPreeclampsia can cause the complication that endanger maternal and fetal, until death. There are many risk factors like extreme age (<20 & >35 years) and nuliparity that can not modify. The objective of this study was to  determine the relationship of maternal age and parity to the incidence of severe preeclampsia.  The research conducted at Medical Record Division of Achmad Mochtar Hospital Bukittinggi about data of all hospitalized patients of obstetrics and gynecology on 2012 – 2013. This research used the analytical method with cross sectional study. Analysis of this research used ratio prevalence and chi-square test with degree of confidence 95%. This research  found 162 case (4.99%) severe preeclampsia. The highest proportion of this case was the extreme age groups (9.90%) and multiparity group (8.68%). Analysis with the ratio prevalence concluded that extreme age is a risk factor for severe preeclampsia (RP=1.476; CI= 1.094 – 1.922) and nuliparity can not determined wheather a risk factor or protective factor (RP= 0.765; CI= 0.565 – 1.034). Analysis with chi-square test concluded that there is a significant relationship between age with severe preeclampsia (p= 0.014<0.05) and there is no significant relationship between parity with severe preeclampsia (p= 0.096>0.05).Keywords: preeclampsia, risk factors, age, parity


2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
A. Ortega-Pacheco ◽  
K. Y. Acosta Viana ◽  
E. Guzmán-Marín ◽  
J. C. Segura-Correa ◽  
M. Álvarez-Fleites ◽  
...  

The objective of this study was to estimate the prevalence and identify risk factors associated with the presence ofToxoplasma gondiiin pig-fattening farms from Yucatan, Mexico. A cross-sectional study was conducted with a two-stage sampling. There were 429 pigs sampled from 39 farms randomly selected. Blood samples were collected to obtain DNA and serum. The presence of IgM and IgG antibodies was determined by indirect ELISA. Prevalence was estimated by diagnostic test. Potential risk factors to be included in a marginal logistic regression were tested by chi-square or Fisher. The prevalence of IgM and IgG was 92.5% (397/429) (CI 89.9–95.1%) and 95.8% (411/429) (CI 93.7–97.8%), respectively. Regarding PCR, a prevalence of 50.8% (218/429) (CI 45.9–55.6%) was found. The logistic regression showed an association with herd size and type of feeder (). The risk of a case in farms with ≤400 pigs was 27.9 times higher than in farms with >400 pigs. The manual feeder was a significant protective factor associated with the seropositive againstT. gondii. Results indicate a high circulation ofT. gondiiin pig-fattening farms from Yucatan, finding an increased risk of infection for those farms with less than 400 animals and automatic feeders.


2019 ◽  
Vol 15 ◽  
Author(s):  
Bekalu Getachew Gebreegziabher ◽  
Tesema Etefa Birhanu ◽  
Diriba Dereje Olana ◽  
Behailu Terefe Tesfaye

Background: Stroke is a great public health problem in Ethiopia. According to reports, in-hospital stroke mortality was estimated to be 14.7% in Ethiopia. Despite this, in this country researches done on factors associated with stroke sub-types were inadequate. Objective: To assess the Characteristics and risk factors associated with stroke sub-types among patients admitted to JUMC. Methods and materials: A retrospective cross sectional study was conducted from May 2017 to May 2018 in stroke unit of Jimma University Medical Center. A total of 106 medical charts of patients diagnosed with stroke were reviewed. Checklist comprising of relevant variables was used to collect data. SPSS version 21 was employed for data entry and analysis. Chi-square test was used to point-out association and difference among stroke sub-types. The data was presented using text, tables and figures. Result: From a total of 106 patients, 67(63.2%) were men. The mean ± SD of age was 52.67±12.46 years, and no significant association was found. Of all the patients, 59(55.6%) had ischemic strokes and 47(44.4%) had hemorrhagic strokes. The most common risk factor in the patients was alcohol use with a prevalence of 69.9%. Of all the risk factors, only sex, cigarettes smoking and dyslipidemia were significantly associated to sub-types of stroke. Conclusion: Ischemic stroke was the most common subtype of stroke. Sex of patient, cigarette smoking and dyslipidemia are significantly associated with the two stroke subtypes.


Author(s):  
Joonho Ahn ◽  
So-Jung Ryu ◽  
Jihun Song ◽  
Hyoung-Ryoul Kim

This study aimed to evaluate the association between shift work and dry eye disease (DED) in the general population. The 2011 Korea Health Panel (KHP) was used. Chi-square test and multivariate logistic regression were used to assess the relationship between shift work and DED. Stratification analysis was conducted by sex and age. Overall, the odds ratio (OR) of DED according to shift work did not showed significant results (adjusted OR = 1.230, 95% CI 0.758–1.901). When findings were stratified based on age older or younger than 40 years, the OR of DED increased to 2.85 (95% CI: 1.25–5.90) in shift workers under 40 years of age. Our results show an association between shift work and DED in a group of younger subjects.


BMJ Open ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. e040865
Author(s):  
Weicong Cai ◽  
Shangmin Chen ◽  
Liping Li ◽  
Pengying Yue ◽  
Xiaofan Yu ◽  
...  

ObjectivesData on the problem of physical activity-related injury (PARI) in university students and the risk factors for PARI among different genders are rare. We conducted a multicentre population-based study to investigate the occurrence of PARI and to explore the gender-specific risk factors for PARI among Chinese university students.DesignCross-sectional study.ParticipantsA total of 5341 students in grades 1–3 at eight universities in four Chinese cities were selected to complete the online questionnaires during March and April 2017. The questionnaires assessed sociodemographic characteristics, physical activity PA) involvement, sleep duration, sedentary behaviour and PARI experiences in the past 12 months.Main outcome measuresPARI during the past 12 months.ResultsAmong the 5341 participants, 1293 suffered from at least one PARI in the past 12 months, with an overall incidence rate of 24.2% (males: 26.2%, females: 23.2%) and an injury risk of 0.38 injuries/student/year (males: 0.48, females: 0.32). Over half of the injured (57.3%) experienced a withdrawal time of PA and nearly two-fifths (39.6%) required medical attention. Irrespective of gender, Shantou and Xi’an students, sports team members and those who engaged in sports and leisure-time vigorous-intensity PA (VPA) at a higher frequency were more likely to suffer from PARI. Male students who participated in sports and leisure-time VPA for long durations had a greater likelihood of sustaining PARI, while having a chronic condition and being involved in sports and leisure-time moderate-intensity PA at a higher frequency and longer duration were potential contributors to PARI among females.ConclusionsThe occurrence of PARI and its risk factors differed by gender, which provides a direction towards developing targeted and effective gender-specific preventative programmes to protect Chinese university students from PARI.


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