A brief overview of classical natural product drug synthesis and bioactivity​

Author(s):  
Li Gen ◽  
Lou Mingliang ◽  
Xiangbing Qi

Traditional medicines consisting of compounds derived from natural organisms have been used for human health care worldwide since ancient times. Since the last century, huge numbers of bioactive natural entities...

2021 ◽  
Vol 5 (1) ◽  
pp. 066-088
Author(s):  
Olugbenga Kayode Popoola ◽  
Kayode Damilola Adekeye ◽  
Eunice Damilola Akinbinu ◽  
Lanre Tope Adekeye ◽  
Michael Bolaji Afolayan ◽  
...  

Since ancient times, plants with medicinal properties possessing no or little toxicological potentials have been relevant for the treatment of several diseases and healing purposes. Medicinal plants serve as important therapeutic agents and valuable resources for manufacturing numerous modern and traditional medicines. Many developing nations still rely on herbal remedies as their mainstay of health-care. This review study is aimed to report the trado-medicinal values of some ethnobotanical plants commonly used in traditional formulations as well as the scientific investigations of these plants for their acclaimed use in traditional practices. Essential phytochemicals and bioactive compounds of these plants are also reviewed.


2021 ◽  
Vol 11 (21) ◽  
pp. 10220
Author(s):  
Hari Prasad Devkota

Medicinal plants have been used for the maintenance of human health since ancient times in the form of food, spices, and traditional medicines [...]


1990 ◽  
Vol 7 (1) ◽  
pp. 89-90
Author(s):  
Dennis Michael Warren

The late Dr. Fazlur Rahman, Harold H. Swift Distinguished Service Professor of Islamic Thought at the Oriental Institute of the University of Chicago, has written this book as number seven in the series on Health/Medicine and the Faith Traditions. This series has been sponsored as an interfaith program by The Park Ridge Center, an Institute for the study of health, faith, and ethics. Professor Rahman has stated that his study is "an attempt to portray the relationship of Islam as a system of faith and as a tradition to human health and health care: What value does Islam attach to human well-being-spiritual, mental, and physical-and what inspiration has it given Muslims to realize that value?" (xiii). Although he makes it quite clear that he has not attempted to write a history of medicine in Islam, readers will find considerable depth in his treatment of the historical development of medicine under the influence of Islamic traditions. The book begins with a general historical introduction to Islam, meant primarily for readers with limited background and understanding of Islam. Following the introduction are six chapters devoted to the concepts of wellness and illness in Islamic thought, the religious valuation of medicine in Islam, an overview of Prophetic Medicine, Islamic approaches to medical care and medical ethics, and the relationship of the concepts of birth, contraception, abortion, sexuality, and death to well-being in Islamic culture. The basis for Dr. Rahman's study rests on the explication of the concepts of well-being, illness, suffering, and destiny in the Islamic worldview. He describes Islam as a system of faith with strong traditions linking that faith with concepts of human health and systems for providing health care. He explains the value which Islam attaches to human spiritual, mental, and physical well-being. Aspects of spiritual medicine in the Islamic tradition are explained. The dietary Jaws and other orthodox restrictions are described as part of Prophetic Medicine. The religious valuation of medicine based on the Hadith is compared and contrasted with that found in the scientific medical tradition. The history of institutionalized medical care in the Islamic World is traced to awqaf, pious endowments used to support health services, hospices, mosques, and educational institutions. Dr. Rahman then describes the ...


Author(s):  
Anniek de Ruijter

This book describes the expansion of EU power in health care and public health and analyses the implications of this expansion on EU health values and rights. The main conclusion of the book is that the EU is de facto balancing fundamental rights and values relating to health, implicitly taking on obligations for safeguarding fundamental rights in the field of health and affecting individuals’ rights sometimes without an explicit legal competence to do so. This brings to light instances where EU health policy has implications for fundamental rights and values without the possibility to challenge the exercise of power of the EU in human health. This begs the question of whether subsidiarity is still the most relevant legal principle for the division of powers and tasks among the Member States, particularly when EU policy and law involves the politically sensitive areas of health care and public health. This question draws out the parameter for continuing the debate on the role of the European Union in promoting its own values and the wellbeing of its peoples, in light of its ever-growing role in human health issues.


2021 ◽  
pp. 002203452110018
Author(s):  
J.T. Wright ◽  
M.C. Herzberg

Our ability to unravel the mysteries of human health and disease have changed dramatically over the past 2 decades. Decoding health and disease has been facilitated by the recent availability of high-throughput genomics and multi-omics analyses and the companion tools of advanced informatics and computational science. Understanding of the human genome and its influence on phenotype continues to advance through genotyping large populations and using “light phenotyping” approaches in combination with smaller subsets of the population being evaluated using “deep phenotyping” approaches. Using our capability to integrate and jointly analyze genomic data with other multi-omic data, the knowledge of genotype-phenotype relationships and associated genetic pathways and functions is being advanced. Understanding genotype-phenotype relationships that discriminate human health from disease is speculated to facilitate predictive, precision health care and change modes of health care delivery. The American Association for Dental Research Fall Focused Symposium assembled experts to discuss how studies of genotype-phenotype relationships are illuminating the pathophysiology of craniofacial diseases and developmental biology. Although the breadth of the topic did not allow all areas of dental, oral, and craniofacial research to be addressed (e.g., cancer), the importance and power of integrating genomic, phenomic, and other -omic data are illustrated using a variety of examples. The 8 Fall Focused talks presented different methodological approaches for ascertaining study populations and evaluating population variance and phenotyping approaches. These advances are reviewed in this summary.


2021 ◽  
Vol 11 (10) ◽  
pp. 4613
Author(s):  
Gabriela-Maria Baci ◽  
Alexandra-Antonia Cucu ◽  
Adela Ramona Moise ◽  
Daniel Severus Dezmirean

Since ancient times, honey has been considered one of the most illustrious and esteemed natural products. Honey plays two key roles; specifically, it is an appreciated nutritional product, and also exhibits a wide range of beneficial properties for human health as a therapeutic agent. Furthermore, it has been shown that honey has valuable effects on the biological and physiological features of mulberry silkworms (Bombyx mori). Bombyx mori exhibits importance not only for the economy, but it also serves as an important biotechnological bioreactor for the production of recombinant proteins that have a great impact in the medical field and beyond. It also represents an important model organism for life sciences. In view of the fact that silk fibroin serves as a natural biopolymer that displays high biocompatibility with human organisms and due to honey’s various and remarkable properties for human health, the two elements are currently used together in order to develop ideal biomaterials for a wide range of purposes. In this review, by discussing the applicability of honey on Bombyx mori and beyond, the importance of honey for life sciences and related fields is spotlighted.


2004 ◽  
Vol 42 (sup1) ◽  
pp. 46-63 ◽  
Author(s):  
Tamara P. Kondratyuk ◽  
John M. Pezzuto
Keyword(s):  

2012 ◽  
Vol 178-181 ◽  
pp. 747-750
Author(s):  
Yu Guo Zhuo ◽  
Jun Liu

The concept and occurrence mechanism of negative air ions (NAI) was introduced and its health care function was described. Through observing NAI concentration of six spots in Beidaihe in China, NAI evaluation standard which has seven grades is put up and the relationship between negative air ion quantity and human health is clarified clearly.


2021 ◽  
Author(s):  
Zahra Zarei Jelyani ◽  
Sadra Valiee ◽  
Mohammad Kia ◽  
Ali jajarmizadeh ◽  
Sajad Delavari

Abstract Introduction: Generally, in Epidemics, such as COVID-19, health care workers (HCWs) faces many problems which lead to a shortage and weakening of human resources in the health system. Therefore, using effective strategies to retain human resources is one of the most important issues during outbreaks. This study aims to collect and classify the proposed interventions to strengthen human health resources and their sustainability during epidemics through scoping review.Methods: In this scoping review study, 2300 studies were retrieved through searching international databases –PubMed, Embase, Scopus and Web of Science. The retrieved studies were screened, and finally, 50 studies were included for analysis. The strategies were classified using inductive qualitative content analysis.Results: Most of the studies were conducted in the United States and the United Kingdom. The target population in 39 studies was all health workers; five studies were on physicians, five studies on nurses, and only one study on dentists. The proposed interventions were classified into five categories: preparation, protection, support, treatment, and feedback. Discussion: Most studies focused on providing interventions in one or two dimensions of human resources, but these interventions were summarized and categorized in this review. Therefore, this study has a holistic view of various dimensions of strengthening and maintaining human health resources during epidemics by providing a thematic map. Considering that human beings are multidimensional, policymakers and managers of the health system should use a set of interventions that simultaneously cover different aspects of their needs to strengthen and maintain HCWs.


Author(s):  
Rohit Rastogi ◽  
Mamta Saxena ◽  
Mayank Gupta ◽  
Akshit Rajan Rastogi ◽  
Pradeep Kumar ◽  
...  

From ancient times, humans are striving for being healthy and to live with mental peace with family and society. In the previous centuries also, some manmade and mostly natural disasters have disturbed the pace of human life. There have been times when the whole human race has been in terror, danger, and utmost worry. The electrical gadgets also have made the human life comfortable, but also machines have dominated its consciousness. The stress, aggression, depression, and many more issues are also showing presence in all our lives. The chapter is a trial to establish the effect of yagna and mantra science over human calmness and its effect on human health irrespective to gender and age. The article also elaborates the effect of Sanskrit sound and mantra chanting on emission of radiations from electronic gadgets. It also presents the effect of spiritual practices on the human body and soul after the terror, stress, grief created due to COVID-19.


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