scholarly journals ON ALIMENTARY LEUCOCYTOSIS IN ITS RELATION TO THE "CRISE HÉMOCLASIQUE" OF WIDAL

1922 ◽  
Vol 36 (4) ◽  
pp. 415-426 ◽  
Author(s):  
W. Storm van Leeuwen ◽  
Z. Bien ◽  
H. Varekamp
Keyword(s):  
Blood Pressure ◽  
Causative Agent ◽  
Blood Cells ◽  
White Blood Cells ◽  
The Body ◽  
Short Intervals ◽  
Sharp Fall ◽  
Normal Individuals ◽  
Slow Rise ◽  
Similar Decrease

Counts of the number of white blood cells at short intervals after the ingestion of a meal (meat, eggs, milk, rice, or butter) in normal individuals and in a number of asthmatics reveal the following facts. As a rule, a sharp fall in the leucocytic curve occurs within 1 or 2 minutes after the meal; generally the curve rises within 10 to 20 minutes, but often a second fall follows 30 to 50 minutes after the meal. This may be followed by a slow rise in the curve (physiological leucocytosis). The first sharp fall is often accompanied by a similar decrease in red cells, the leucocytic formula is not changed, the blood pressure also remains unchanged, and this makes it probable that the leucopenia observed is only a manifestation of a change in distribution of the blood in different regions of the body. Not infrequently the leucocyte curve after ingestion of food shows a form differing considerably from that described above. Counts of white cells made at intervals of 20 minutes in the same patient at different times but after ingestion of the same food show very different leucocytic curves. Such counts do not give evidence of the existence of a crise hémoclasique and consequently cannot be used to identify the causative agent of cases of hypersensitiveness to foodstuffs or drugs. Whether such an identification can be obtained if instead of simply counting white cells the whole complex of symptoms originally described by Widal as characteristic for a crise hémoclasique is used, remains undetermined by our work.

scholarly journals Traffic Related Air Pollution Exposure Effect on Circulating White Blood Cell Counts in Healthy Individuals

2021 ◽  
Vol 8 (1) ◽  
pp. 106-113
Author(s):  
Anjam Shezadi ◽  
Muhammad Shahbaz ◽  
Irfan Baboo ◽  
Faiza Shakir ◽  
Misbah Shoukat
Keyword(s):  
Blood Pressure ◽  
Air Pollution ◽  
Blood Cells ◽  
White Blood Cells ◽  
The Body ◽  
Blood Samples ◽  
Exposure Effect ◽  
Cell Counts ◽  
Exhaust Fumes ◽  
White Blood Cell Counts

During this short term study a total of 110 samples were collected from the selected individuals of study area. This study was aimed to count the White blood cells in the blood samples of individuals, who were mostly exposed to exhaust fumes (air pollution), like traffic constables, cooks and shopkeepers. For this purpose blood samples were taken into an evacuee container having anticoagulant Ethylene diamine tetra-acetic acid (EDTA) so to prevent coagulation of blood, for the count of WBCs, heamocyto-meter was used. During the study the body mass index and blood pressure was also measured by digital blood pressure measuring apparatus. Samples were observed under the microscope. It was found that 15% (13,133±2544.081) sampled individuals had increased WBCs and 85% (7821±1482.76) normal WBCs. In female samples 50% (11900±2151.27) were observed with above range of WBCs and other 50% (8540±844.39) with normal range of WBCs count, non-had WBCs count lower than the normal WBCs. Mostly had normal and few had above the range. One way ANOVA has been used to analyze connection of exposure to air pollution with counts of circulating white blood cells.

scholarly journals EFFECT OF ZINC ELEMENT AND DEXAMETHASONE ON SOME HEMATOLOGICAL BIOCHEMICAL TESTS IN RABBITS MALE

2016 ◽  
Vol 47 (6) ◽  
Author(s):  
D. S. Dheyab
Keyword(s):  
Blood Cells ◽  
White Blood Cells ◽  
The Body ◽  
Control Group ◽  
Blood Collection ◽  
Biochemical Tests ◽  
Histological Changes ◽  
Spleen Tissue ◽  
Cholesterol Levels ◽  
Short Time

This study was conducted to investigate the effect of zinc in dose 15mg/kg.bw daily  taken by the mouth and dexamethasone 4mgIkg.Bw by injection for 30days on some hematological biochemical tests and some histological changes of liver spleen in male rabbits. Thirty rabbits were used that divided into 3 randomized groups (each group contain 10 male rabbits ). Control group was taken normal food and water, Zinc group that gave zinc at dose of 15mg/kg.BW/daily/oral on 1, 2, 3, 4 weeks. Dexamethasone with zinc group : Employ dexamethasone 4mg/Kg.Bw . I.M dialy for 1 and 2 weeks for experiment and at  3, 4th weeks they gave zn 15mg/lKg.Bw day/orally. Blood samples were taken from the heart directly in 2 and 4weeks to examine packed cell volume (pcv), white blood cells (WBCs), Red blood cells (RBCs) with differential Leuckcyte count.separation blood collection to plasma and examine glucose mg/dl , cholesterol mg/dl. In histological tests, rabbits were killed and separate their organs tissue from the body to examine liver and spleen. The results revealed  a decrease in level of RBCs, pcv after treatment with zinc 15, mg/Kg.Bw orally (zinc group) and increase in WBCs with differential leuckocyte count specially neutrophil cell, while biochemical tests show increase in glucose and cholesterol levels after treatment with dexamethasone 4mglkgBw. I/M seen increase in counts of RBCs , PCV, WBCs and differential lenkocyte count and decrease in glucose with cholesterol parameters, histological changes show change in liver after treatment by dexamethasone 4mglKg.Bw ,spleen tissue seen necrosis and pigmentation with hemorrhage after take dexamethasone 4mglkg in (dexamethasone + zinc group). Results also showed that zinc enhanced the immune system in at normal dose for limited time  because of its effect on other mineral such as copper and causes anemia , while the dexamethasone is a drug used for antianflammatory but for a short time.                                                                                                                           

scholarly journals Anthrax Toxin Characterization

2002 ◽  
Vol 45 (1) ◽  
pp. 3-5 ◽  
Author(s):  
Jiří Patočka ◽  
Miroslav Špliňo
Keyword(s):  
Blood Cells ◽  
Protective Antigen ◽  
Lethal Factor ◽  
White Blood Cells ◽  
The Body ◽  
Anthrax Toxin ◽  
Signaling System ◽  
Animal Cells ◽  
The Third ◽  
Edema Factor

The anthrax toxin comprises three proteins. When they work together, they can kill humans, especially after spores of the bacteria have been inhaled. One anthrax protein, called protective antigen (PA), chaperones the two other toxins into human or animal cells and shields them from the body’s immune system. The second, lethal factor (LF), destroys the white blood cells that hosts send in defence. The third toxin molecule, edema factor (EF), hijacks the signaling system in the body. This disrupts the energy balance of cells and leads to them accumulating fluid and complete destroy of cells.

scholarly journals Effects of Inclusion of Different Doses of Persicaria odorata Leaf Meal (POLM) in Broiler Chicken Feed on Biochemical and Haematological Blood Indicators and Liver Histomorphological Changes

Animals ◽  
2020 ◽  
Vol 10 (7) ◽  
pp. 1209 ◽  
Author(s):  
Muhammad Abdul Basit ◽  
Arifah Abdul Kadir ◽  
Teck Loh ◽  
Saleha Abdul Aziz ◽  
Annas Salleh ◽  
...  
Keyword(s):  
Growth Performance ◽  
Blood Cells ◽  
Broiler Chickens ◽  
White Blood Cells ◽  
Serum Levels ◽  
Linear Increase ◽  
The Body ◽  
Leaf Meal ◽  
Serum Activity ◽  
Haematological Indices

This research was conducted to estimate the effects of Persicaria odorata leaf meal (POLM) on haematological indices, serum biochemical attributes, and internal organs parameters, including histomorphological features of the liver, in broiler chickens. A total of 120 one-day-old male broiler chicks (Cobb-500) were randomly allocated into four experimental groups. The dietary treatments were basal diet (BD), which served as the control (C), along with BD + 2 g/kg POLM (Po2), BD + 4 g/kg POLM (Po4), BD + 8 g/kg POLM (Po8), which were the supplemented groups. The body weight gain (BWG) showed a linear increase and feed conversion ratio (FCR) showed a linear decrease with increasing POLM dosage at day 42 (p ˂ 0.05) and for the overall growth performance period (p ˂ 0.01). On day 21 and day 42, the values of red blood cells (RBCs), white blood cells (WBCs), haemoglobin (Hb), and packed cell volume (PCV) showed linear increases (p ˂0.05) as the dosage of POLM increased in the diet. On day 21, dietary supplementation of POLM linearly decreased (p ˂ 0.05) the serum activity of alkaline phosphatase (ALP), aspartate aminotransaminase (AST), alanine aminotransaminase (ALT), and serum levels of urea and creatinine. On the other hand, serum levels of total protein (TP), albumin, and globulin showed a linear increase (p ˂ 0.05) as the POLM dosage increased. On day 42, the serum activity of AST and ALT and serum levels of glucose, cholesterol, triglycerides, urea, and creatinine showed linear decreases (p ˂ 0.05) with increased levels of POLM in the diet. However, POLM supplementation linearly increased (p ˂ 0.05) the serum levels of TP and globulin. Dietary inclusion of POLM did not influence the organ parameters and showed no adverse effects on the liver histomorphology. In conclusion, supplementation of POLM increased the growth performance, improving haematological indices and serum biochemistry profiles of broiler chickens without any deleterious effects on the liver histomorphology. The results of the present study provide evidence that POLM can be safely used at a dose rate of 8 g/kg of feed as an alternative to conventional antimicrobial growth promoters (AGPs).

Associations between white blood cells count and obesity in apparently healthy young adults

2020 ◽  
Vol 50 (6) ◽  
pp. 1013-1019
Author(s):  
Fatemeh Ghannadiasl
Keyword(s):  
Young Adults ◽  
Cardiovascular Diseases ◽  
Blood Cells ◽  
White Blood Cells ◽  
Cross Sectional Study ◽  
The Body ◽  
Sectional Study ◽  
Cross Sectional ◽  
Content Type ◽  
Apparently Healthy

Purpose The elevated white blood cells (WBCs) count has been reported to be a predictor of cardiovascular diseases, diabetes, hypertension and metabolic syndrome. This study aims to determine the associations between WBCs count and obesity in apparently healthy young adults. Design/methodology/approach In this cross-sectional study, the authors evaluated the body mass index (BMI) in 392 apparently healthy young adults of both sexes. The WBCs count was measured using standard counter techniques. The inclusion criteria were the agreement to participate in the study, between 18 and 25 years of age, lack of self-reported diseases such as cardiovascular diseases, hypertension, kidney and infectious diseases. Findings According to the BMI classification, underweight and overweight or obesity were observed in 14.58 and 11.48 per cent of young adults, respectively. The mean WBC was 6.5 ± 1.5 (×10³ cells/µL). Higher values of WBCs were found in women than in men (p = 0.02). The young adults with higher BMI had a higher WBCs count. There was a positive correlation between WBCs count and weight and BMI (r = 0.19 and r = 0.22, p < 0.001, respectively). Research limitations/implications This research was a cross-sectional study. Future studies are suggested using longitudinal studies to examine more relationships between obesity and WBCs count in apparently healthy young adults. Practical implications The results of this study provide evidence for weight management in this age group to reduce diseases associated with increased WBCs count. Originality/value The WBCs count was related to increasing levels of BMI per cent 2 C even in the normal range.

scholarly journals Quantification and three-dimensional microanatomical organization of the bone marrow

2017 ◽  
Vol 1 (6) ◽  
pp. 407-416 ◽  
Author(s):  
Cesar Nombela-Arrieta ◽  
Markus G. Manz
Keyword(s):  
Bone Marrow ◽  
Blood Cells ◽  
Structural Organization ◽  
Imaging Techniques ◽  
White Blood Cells ◽  
Three Dimensional ◽  
The Body ◽  
Cellular Composition ◽  
Spatial Logic ◽  
Health And Disease

Abstract Bone marrow (BM) constitutes one of the largest organs in mice and humans, continuously generating, in a highly regulated manner, red blood cells, platelets, and white blood cells that together form the majority of cells of the body. In this review, we provide a quantitative overview of BM cellular composition, we summarize emerging knowledge on its structural organization and cellular niches, and we argue for the need of multidimensional approaches such as recently developed imaging techniques to uncover the complex spatial logic that underlies BM function in health and disease.

Relationships between plasma adiponectin and blood cells, hepatopancreatic enzymes in women

2004 ◽  
Vol 91 (02) ◽  
pp. 360-366 ◽  
Author(s):  
Katsuhiko Namioka ◽  
Shinji Katayose ◽  
Miyao Matsubara
Keyword(s):  
Insulin Resistance ◽  
Blood Pressure ◽  
Bone Marrow ◽  
Blood Cells ◽  
White Blood Cells ◽  
Serum Triglyceride ◽  
Plasma Adiponectin ◽  
The Metabolic Syndrome ◽  
Before And After ◽  
Bone Marrow Function

SummaryAdiponectin, which is secreted specifically from adipocyte, is thought to play a key role in the metabolic syndrome. We studied the associations of plasma adiponectin concentrations with blood cells and hepatopancreatic enzymes in 339 women aged 54.0 ± 0.8 (mean ± SE) years. Plasma adiponectin before and after adjustment for body composition or calculated insulin resistance increased in slight anemic women (372.6 ± 2.6 ×104/mm3) compared with non-anemic subjects (471.1 ± 1.7) (all p < 0.0001), and were inversely associated with red blood cells (RBC), hemoglobin, hematocrit, white blood cells and platelet values (p < 0.0001 ∼ 0.02), independent of age, diastolic blood pressure, body mass index, serum triglyceride, insulin resistance or blood urea nitrogen. Age and adiponectin/body fat mass (%) were negative, and blood pressure and insulin resistance were positive significant independent determinants of RBC in stepwise regression analysis. Moreover, adiponectin before and after adjustment were inversely associated with serum ALAT,γGTP and ChE, and positively with amylase levels (p < 0.0001 ∼ 0.02). These results indicate the possibility that increased adiponectin may contribute to the suppressive bone marrow function in vivo. Combined with the leptin’s data, adipocyte derived proteins were related to the hematopoiesis, therefore it has shown the possible existence of adipose tissue/ bone marrow function linkage more clearly. Furthermore, hepatopancreatic enzyme associations with this protein may indicate the possibility that adiponectin will regulate the hepatopancreatic function in health and disease.

Non-specific protection of the body of la-boratory rats under the influence of experimental hypoxia

2020 ◽  
Vol 3 ◽  
pp. 116-123
Author(s):  
F.I. Alistratova ◽  
Keyword(s):  
Blood Cells ◽  
Blood Test ◽  
White Blood Cells ◽  
The Body ◽  
Urgent Problem ◽  
Adaptive Capabilities ◽  
First Case ◽  
Group A ◽  
Adaptive Reactions

To date, the search for the most informa-tive and simple methods for diagnose of adaptive capabilities is an urgent problem of veterinary medicine and adaptive physiolo-gy. The direction of the animal body's re-sponse to the hypoxic factor has not been sufficiently studied. Objective: the analyze of the dynamics of changes of the main indi-cators in the leukogram under the influence of hypoxia, as well as the study of the role of leukocyte, indices the analysis of the level of resistance in rats. The animals were divided into two groups: in the first case, the animals were injected with cytoflavin at a dose of 135 mg/kg before the hypoxia ses-sion, and in the second case, saline was ad-ministered at an equivalent dose. The blood test was performed on a hematological auto-matic analyzer, and the clinical parameters of peripheral blood were determined. Mathe-matically, the leukogram was used to deter-mine: the white blood cell shift index (ISLC), the lymphocyte-monocyte ratio in-dex (ISLM), and the lymphocyte-granulocyte index (ILG). The results of the study showed that the course of hypoxia contributes to a number of changes in the blood composition, for 21 days. There was an increase in the number of white blood cells in both groups, a change in the parame-ters of the leukocyte formula-a decrease in the content of lymphocytes, with a simulta-neous increase in the proportion of mono-cytes. The use of interval hypoxia caused a decrease in the content of red blood cells in animals of the first group, a decrease in the concentration of hemoglobin and hematocrit in both groups studied. The number of plate-lets increased, which also indicates the start of adaptive reactions in the body of rats. The use of leukocyte indices is the assess to the level of resistance of the body and showed their high significance and informa-tive value in modeling experimental hypoxia.

scholarly journals ON THE RELATION OF THE CATALYTIC ACTIVITY OF THE BLOOD TO THE NUMBER OF RED BLOOD CELLS IN HEALTH, AND TO THE NUMBER OF WHITE BLOOD CELLS AND THE BODY TEMPERATURE IN PERITONITIS

1910 ◽  
Vol 12 (1) ◽  
pp. 1-11 ◽  
Author(s):  
M. C. Winternitz ◽  
J. P. Pratt
Keyword(s):  
Catalytic Activity ◽  
Body Temperature ◽  
Red Blood Cells ◽  
Blood Cells ◽  
Blood Count ◽  
Corpus Striatum ◽  
White Blood Cells ◽  
The Body ◽  
White Blood Count ◽  
Large Animals

The catalytic activity of the blood of normal rabbits varies almost directly with the volume and number of red blood cells. This explains to a certain extent at least why animals of the same general degree of nutrition, and of the same litter, should have about the same activity since they are likely to have the same number of red blood cells, and why healthy large animals should read high while small poorly nourished ones should read low. Accompanying the hyperpyrexia resulting from puncture of the corpus striatum of a rabbit's brain, there is no change in either the catalytic activity of the blood or the white blood count. In experimentally produced peritonitis, the catalytic activity of the blood always rises, and is, therefore, absolutely independent of body temperature and white blood cells since one or both of these may rise, fall or remain stationary while the catalytic action increases.

scholarly journals Hyper Eosinophilia and Dementia

2020 ◽  
Vol 3 (1) ◽  
pp. 01-01
Author(s):  
Paul Cusack
Keyword(s):  
Blood Brain Barrier ◽  
Blood Cells ◽  
Herpes Virus ◽  
Latent Infection ◽  
White Blood Cells ◽  
Nerve Cells ◽  
The Body ◽  
Brain Barrier ◽  
Blood Brain ◽  
Herpès Virus

In this brief paper, we consider how the Herpes Virus could possibly be the culprit when the body responds to a latent infection causing dementia. The over production of white blood cells passing through he Blood-Brain- Barrier leads to death of nerve cells. This is the path toward dementia.

Sign in / Sign up

Export Citation Format

Share Document