91 Individuals Aged 65-69 Years Have Poorer Postural Control Related to Fear of Falling than Individuals Aged 70-74 Years

2019 ◽  
Vol 48 (Supplement_4) ◽  
pp. iv18-iv27
Author(s):  
Sumaiyah Mat ◽  
Chin Teck Ng ◽  
Maw Pin Tan
Keyword(s):  
Older People ◽  
Postural Control ◽  
Fear Of Falling ◽  
Balance Control ◽  
Age Groups ◽  
P Value ◽  
Age Group ◽  
Eyes Closed ◽  
Significant Difference ◽  
History Of

Abstract Background Fear of falling (FoF) is common in older people with a history of falls and increases the risk of future falls. It is postulated that individuals with FoF may lose the balance control in response to threatening situations due to psycho-emotional responses to a previous event. Little is known of how FoF influences postural control in older people. Aim To compare the influence of age in the association between FoF and postural control among older persons Methods A case-control study involving individuals aged ≥65 years with ≥2 falls or one injurious fall over 12 months with volunteers aged ≥65 years with no falls in the past year. Postural sway was quantified by using a long force-plate balance platform (Balancemaster, NeuroCom, USA). Fear of falling was assessed using the short Falls Efficacy Scale-International questionnaire. Result Of 102 participants recruited in this study, 33 (32.4%) were aged 65-69y, 36 (35.3%) aged 70-74y, and 33 (32.4%) age≥ 75y. There was no significant difference in FoF across the groups. The oldest age group had poorer postural control. Fear of falling in the youngest old group was associated with poorer standing balance in ‘eyes closed, firm surface’ conditions (p-value=0.012), forward maximal excursion (p-value=0.007), forward end point (p-value=0.001), forward movement velocity (p-value=0.008) and forward directional control (p-value <0.001). The associations remained significant even after adjustment of history of falls, body mass index and comorbidities. Conclusion The influence of FoF on postural control is age dependent with posturography measurements only significantly associated with FoF within the 65-69y age group, but not the 70-74y or ≥ 75y age groups. Psychological interventions for fall prevention may therefore be more appropriately targeted according to age groups, rather than treating all over 65s as a homogenous group. This approach should be evaluated in future studies.

scholarly journals Astigmatic change after pterygium excision with autologous limbal conjunctival graft

2020 ◽  
Vol 9 (1) ◽  
pp. 25-30
Author(s):  
Dikchhya Sharma ◽  
Gunjan Prasai ◽  
Om Krishna Malla
Keyword(s):  
Age Groups ◽  
College Teaching ◽  
Corneal Astigmatism ◽  
P Value ◽  
Ocular Surgery ◽  
Medical College ◽  
Corneal Scarring ◽  
Significant Difference ◽  
History Of ◽  
Pterygium Excision

Background: Pterygium induces a significant amount of astigmatism. Pterygium excision with conjunctival limbal autograft results in significant reduction in astigmatism by inducing a reversal of pterygium induced corneal flattening thereby improving the vision. Objectives: The aim of this study was to investigate the amount of corneal astigmatism in patients with pterygium before and one month (4 weeks) after surgery.  Methodology: The prospective observational study was conducted in 31 patients who underwent pterygium excision with limbal autograft in Kathmandu Medical College Teaching Hospital during the study period of 12 months duration. Patients with recurrent pterygium, pseudopterygium, history of ocular trauma, history of ocular surgery, corneal scarring were excluded from the study. After surgery, patients were followed for four weeks. Findings were recorded in the proforma and statistical analysis was done in SPSS version 19.   Results: Pterygium was seen in all age groups with majority being in the active age range of 41-50 yrs. Females were most commonly affected. Significant difference in corneal astigmatism was noted postoperatively with a p value being 0.01. Conclusion: The technique of pterygium excision with limbal conjunctival autograft not only reduces the chances of recurrence but also helps in reducing the induced corneal astigmatism which is responsible for decreased vision in patients with pterygium.

scholarly journals Association of MTR A2756G Gene Polymorphism with Risk of Head and Neck Cancer

2020 ◽  
Vol 1 (3) ◽  
pp. 6
Author(s):  
Muhammad Tahir ◽  
Aamer Ali Khattak ◽  
Erum Monis ◽  
Sana Gul
Keyword(s):  
Head And Neck ◽  
Age Groups ◽  
P Value ◽  
Chi Square ◽  
Normal Individuals ◽  
Increased Risk ◽  
Significant Difference ◽  
Pcr Rflp ◽  
Chi Square Test ◽  
History Of

Objective: To perform genotyping for MTR A2756G polymorphism and identification of risk factors associated with head and neck squamous cell carcinoma (HNSCC). Study Design: Cross section, comparative study. Place and Duration of Study: The study was carried out at the Department of Biochemistry of Quaid-i- Azam University, Islamabad from October 2014 to August 2015. Materials and Methods: In this study, 292 diagnosed patients HNSCC and 324 normal individuals without any history of cancer were enrolled. Blood samples of patients and controls were collected in ethylenediamine tetra acetic acid (EDTA) and DNA was extracted using conventional method. All samples were genotyped for the MTR A2756G polymorphism using PCR-RFLP. Frequency of polymorphism was compared between HNSCC patients andcontrols. MultipleLogisticRegression(MLR)andchi-squaretestwasperformedtoexaminetheassociation of MTR A2756G polymorphism with risk factor. Results: Chi-square test of independence showed statistically significant difference among the variables of age, smoking and MTR A2756G genotype (p-value<0.05). Multivariate analysis showed that smoking (adjusted OR, 3.7; 95% CI, 2.3 – 6.0), age groups 41 – 50 years (adjusted OR, 3.6; 95% CI, .9 – 6.7) and > 60 years (adjusted OR, 3.5; 95% CI, 1.7 – 7.3), MTR 2756 AG genotype (adjusted OR, 2.1; 95% CI, 1.3 – 3.5) is associated with increased risk of HNSCC. Conclusion: The results suggest that the genetic polymorphism MTR A2756G is associated with the occurrence of HNSCC in the Pakistani population while the individuals between 40 to 50 years of age and those who are smokers are at a greater risk of developing HNSCC.

scholarly journals Scabies outbreaks during 2019 in Al- Daseem, Al-Rusafa-Baghdad: A retrospective study

2021 ◽  
Vol 63 (2) ◽  
pp. 65-69
Author(s):  
Bashar A. Abdul Razzaq ◽  
Tuka Y. Hassan
Keyword(s):  
Family Member ◽  
Rural Areas ◽  
Skin Diseases ◽  
Age Groups ◽  
Personal Contact ◽  
Poor People ◽  
Age Group ◽  
Increased Risk ◽  
Significant Difference ◽  
History Of

Abstract Background: Scabies is a skin infestation by the Sarcoptes scabiei mite. Scabies is transmitted through close personal contact. Settings like hospitals, prisons and childcare centers are at greater risk of outbreaks. Both male and female may be infected with scabies in any age groups. It is common in tropical climate countries poor people who live in rural areas and among displaced patients. It rises significantly among low economic status because skin diseases are significantly associated with a higher crowding index. Objectives: To estimate the prevalence of scabies in Al- Daseem region and identify factors associated with an increased risk of scabies among patients.   Methodology: A retrospective cross sectional study was carried out about scabies outbreak in Al- Daseem area which located at Al-Rusafa side in Baghdad during 2019. Basic data were obtained from records of communicable disease section/public health director / Al-Rusafa health directorate. All registered cases during 2019 were included in the study, and then data computerized and analyzed using SPSS version 23 using frequency tables for the selected variables under study. Participants represented by students of Ali Al Wardi School (the only school in Al Daseem area) and from people live in this area (20% of them selected randomly). Data included socio-demographic information (age, sex, family member, and treatment). The diagnosis of scabies was based on their typical history of (itching that worsens at night, the distribution of lesions, and a history of contact with other family member infected with scabies).   Results: A total of 11363 participants information were obtained from database, 6473were male and 4873 were female. There were 746 (6.6% of total) participants infected with scabies of them, there were 457 (7%) male patients and 289 (5.9%) female patients. There was significant association between scabies and gender of patients, P=0.018. According to the age groups of patients, there were 161 (6.4%) patients 6 years old, 337 (8.8%) patients within (7-12 years) age group, 82         (6.7%) patients within (13-19 years) age group, and there were 166 (4.3%) patients 20 years old. There was a significant difference between scabies and age group, p<0.001. Of the total patients, there were 622 (85%) patients had another family member infected with scabies. There was a significant association between patients and having another family member infected with it, P<0.001. Conclusion: prevalence of scabies in Al-Daseem region was (6.6%). Scabies was dominant among male, age group of (7-12 years), and having other family member infected with scabies.    Key words:  Scabies, Al-Desame, outbreak, mite, school.

The VKORC1 and CYP2C9 Genotypes Significantly Affect Vitamin K Antagonist Dosing Only in Patients Aged 20 Years or Older

Blood ◽  
2011 ◽  
Vol 118 (21) ◽  
pp. 1243-1243 ◽  
Author(s):  
Ulrike Nowak-Gottl ◽  
Kevin Dietrich ◽  
Andre Franke ◽  
Noha Sharaf El-Din ◽  
Yutaka Yasui ◽  
...  
Keyword(s):  
Vitamin K ◽  
Significant Role ◽  
Conflicts Of Interest ◽  
Vitamin K Antagonists ◽  
Age Groups ◽  
P Value ◽  
Age Group ◽  
Explanatory Variables ◽  
Cyp2c9 Genotype ◽  
Significant Difference

Abstract Abstract 1243 INTRODUCTION: Anticoagulation with Vitamin K antagonists (VKA) is problematic due to difficulties in safely managing dosing. Polymorphisms in cytochrome P450 C9 (CYP2C9) and vitamin K epoxide reductase genes (VKORC1) have been shown to affect VKA dosing in adults. Recently we reported that, in children, the VKORC1 and CYP2C9 genotypes play insignificant roles in explaining variation in VKA dosing (Nowak-Gottl et al. Blood 2010 116:61–1–6105). Given the qualitative differences in the role these polymorphisms play in VKA dosing variation between adults and children, we were interested in determining at what age these polymorphism begin to play a role in variation in VKA dosing. Understanding at which age these genotypes begin to play a significant role will lead to only screening patients in whom there would be potential benefit from the knowledge of their VKA dose related genotypes. METHODS: We performed a prospective cohort study of patient's 1–30 years of age, who were receiving VKA and were considered to be on stable anticoagulation. Stable anticoagulation was defined as a VKA requirement remaining constant for 3 consecutive measurements after achieving the target INR (target INR 2.0–3.0). Blood samples were collected for DNA with which VKORC1 and CYP2C9 genotyping were performed. Patient demographics and data on VKA dose (mg/kg) were collected. The VKA dose (mg/kg) was transformed by taking the square root of the dose values to produce an approximate symmetric distribution. Multiple linear regression of the transformed VKA dose was used to assess its relationship with genetic and clinical/demographic variables. VKORC1 genotypes were categorized into three groups (AA, GA, and GG) and CYP2C9 genotype into two groups (any mutation 1.2, 1.3 or 2.2, and wild type 1.1). Gender and INR were not associated with VKA dose and were removed from the model. The final model used weight, VKORC1 and CYP2C9 genotypes as explanatory variables which were fit for the following age groups: 1– 13 years, 14–19 years, 20–30 years. Weight was used in the model but was highly positively correlated with age and body mass index. A summary of the fitted models (partial R2 and p value) is reported in Table I. RESULTS: A total of 91 patients were recruited (1–13 years n=18, 14–19 years n=44, 20–30 years n=29). The distribution of genotypes in the study population were consistent with previous reports in the literature (VKORC1 AA (12%) GA (43%) GG (45%); CYP2C9 1.1 (68%), 1.2 (20%), 1.3 (14%) 2.2/2.2/3.3 (2%). In the regression model in patients 1–13 years of age and 14–19 years of age, *weight explained the dosing variation significantly and far more than the two genes. The polymorphisms in VKORC1 or CYP2C9 were not significantly associated with VKA dosing in this age range and there was no significant difference in dosing among differing genotypes. In contrast, in the age group 20–30 years, weight was no longer significantly associated with variation in VKA dosing. However, ** VKORC1 and **CYP2C9 were significantly associated with variation in VKA dosing in patients over the age of 20 years. Also, in the 20–30 year age group carriers of VKORC1 AA genotype required significantly lower daily doses than GG genotypes (p-value=0.036). CONCLUSION: Assessing genotypes in patients under the age of 20 has little clinical relevance explaining no more than 12.7% of variation in VKA dosing. Weight or age have a far greater effect on dosing variation under the age of 20 years. However, in patients 20 years of age or older, the VKORC1 and CYP2C9 genotypes play a significant role, explaining 42.5% of the variation in VKA dosing. Designing models based on the differences in the various age groups is important for optimizing VKA dosing. Disclosures: No relevant conflicts of interest to declare.

Seroprevalence of anti-SARS-CoV-2 IgG antibodies in hospitalized patients at a tertiary referral center in North India (Preprint)

2020 ◽  
Author(s):  
Dr. Animesh Ray ◽  
Dr. Komal Singh ◽  
Souvick Chattopadhyay ◽  
Farha Mehdi ◽  
Dr. Gaurav Batra ◽  
...  
Keyword(s):  
Tertiary Care ◽  
Age Groups ◽  
Hospitalized Patients ◽  
North India ◽  
P Value ◽  
Care Hospital ◽  
Igg Antibodies ◽  
Igg Antibody ◽  
Increased Risk ◽  
Significant Difference

BACKGROUND Seroprevalence of IgG antibodies against SARS-CoV-2 is an important tool to estimate the true extent of infection in a population. However, seroprevalence studies have been scarce in South East Asia including India, which, as of now, carries the third largest burden of confirmed cases in the world. The present study aimed to estimate the seroprevalence of anti-SARS-CoV-2 IgG antibody among hospitalized patients at one of the largest government hospital in India OBJECTIVE The primary objective of this study is to estimate the seroprevalence of SARS-CoV-2 antibody among patients admitted to the Medicine ward and ICU METHODS This cross-sectional study, conducted at a tertiary care hospital in North India, recruited consecutive patients who were negative for SARS-CoV-2 by RT-PCR or CB-NAAT. Anti-SARS-CoV-2 IgG antibody levels targeting recombinant spike receptor-binding domain (RBD) protein of SARS CoV-2 were estimated in serum sample by the ELISA method RESULTS A total of 212 hospitalized patients were recruited in the study with mean age (±SD) of 41.2 (±15.4) years and 55% male population. Positive serology against SARS CoV-2 was detected in 19.8%patients(95% CI 14.7-25.8). Residency in Delhi conferred a higher frequency of seropositivity 26.5% (95% CI 19.3-34.7) as compared to that of other states 8% (95% CI 3.0-16.4) with p-value 0.001. No particular age groups or socio-economic strata showed a higher proportion of seropositivity CONCLUSIONS Around, one-fifth of hospitalized patients, who were not diagnosed with COVID-19 before, demonstrated seropositivity against SARS-CoV-2. While there was no significant difference in the different age groups and socio-economic classes; residence in Delhi was associated with increased risk (relative risk of 3.62, 95% CI 1.59-8.21)

scholarly journals Trends of Stomach Cancer in Central Serbia

Medicina ◽  
2021 ◽  
Vol 57 (7) ◽  
pp. 665
Author(s):  
Miodrag M. Stojanovic ◽  
Natasa K. Rancic ◽  
Marija R. Andjelkovic Apostolovic ◽  
Aleksandra M. Ignjatovic ◽  
Mirko V. Ilic
Keyword(s):  
Stomach Cancer ◽  
Preventive Measures ◽  
Age Groups ◽  
Optimal Number ◽  
P Value ◽  
Age Group ◽  
Joinpoint Regression ◽  
Mortality Trends ◽  
Incidence Trend ◽  
Incidence And Mortality

Somach cancer is the third most common cause of cancer-related deaths worldwide. The objective of the paper was to analyze the incidence and mortality trends of stomach cancer in Central Serbia in the period between 1999–2017. Materials and Methods: trends and annual percentage change (APC) of the incidence and mortality rate with corresponding 95% confidence intervals (CI) were calculated by joinpoint regression analyses. The optimal number of Joinpoints was identified using the Monte Carlo permutation method. The trend was considered to be significantly increasing (positive change) or decreasing (negative change) when the p-value was below 0.05 (p < 0.05). Results: the total number of new cases was 16,914 (10,873 males and 6041 females) and the total number of mortality cases was 14,790 (9348 in and 5442 in females). Almost one third (30.8%) of new cases were registered in the 60–69-year age group, and new cases were significantly more frequent in males than in females (30.8% vs. 29.02%, p < 0.001). Joinpoint regression analysis showed a significant decrease of incidence trend in females during the 2000–2015 period with APC of −2.13% (95% CI: −3.8 to −0.5, p < 0.001). An insignificant decrease in incidence trend was in males with APC of −0.72% (95% CI: −2.3 to 0.9, p = 0.30). According to the joinpoint analysis, a significant decrease of mortality trends both in males during 2000–2015 with APC of −2.21% (95% CI: −1.6 to −7.5, p ≤ 0.001 and in females, during the same period, with APC of −1.75% (95% CI: −2.9 to −0.6, p < 0.001) was registered. From 2015 to 2017, a significant increase of mortality was registered with APC of 44.5% (95% CI: from 24.2 to −68.1, p ≤ 0.001) in females and in males with APC of 53.15% (95% CI: 13.5 to −106.6, p ≤ 0.001). Conclusion: a significant decrease of stomach cancer incidence trend in females and insignificant decrease of incidence trend in males were determined in Central Serbia. Based on presented results, the mortality trend decreased significantly both in males and in females during 2000–2015, and from 2015 to 2017 we recorded a significant increase in mortality in both sexes. We found significantly more new cases in women than in men in the age group of 40–49, and the mortality of stomach cancer was significantly more frequent among females compared to males in the age groups 30–39, as well as in the 50–59 age group. There is a need for improving recording and registration of new cases of stomach cancer, especially in females. Urgent primary and secondary preventive measures are needed—introducing stomach cancer screening and early detection of premalignant changes. Urgent primary and secondary preventive measures are needed.

scholarly journals Violence and depression among pregnant women in Egypt

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Hanan M. Ghoneim ◽  
Mohamed Elprince ◽  
Tamer Yehia M. Ali ◽  
Waleed F. Gharieb ◽  
Amal A. Ahmed
Keyword(s):  
Intimate Partner Violence ◽  
Sexual Violence ◽  
Partner Violence ◽  
Strong Association ◽  
Depression Scale ◽  
Intimate Partner ◽  
University Hospital ◽  
P Value ◽  
Significant Difference ◽  
History Of

Abstract Background Depression is a serious mental health disorder that might affect women in the childbearing period. Incidences increase during pregnancy as well as after delivery. Its association with intimate partner violence (defined as physical, sexual, or psychological harm by a current or former partner) has been reported in many countries. Data about this sensitive issue are lacking in Egypt. The aim of the study was to determine the relation between intimate partner violence and depression during pregnancy. Methods This was a case control study conducted at the outpatient clinics in Suez Canal University hospital, from January 2019 to March 2020. The study included two groups, the study group included women exposed to violence during the current pregnancy and a control one included women with no history of violence. Both groups were recruited according to the predetermined inclusion criteria (women aged 18-45 years, continuous marital relationship, no history of depression in current or previous pregnancies, and singleton pregnancy). Women were asked to complete the Arabic validated NorVold Domestic Abuse Questionnaire (measuring four types of abuse: emotional, physical, sexual, and violence in the health care system, the last one being excluded). Depression was evaluated using the Arabic validated form of the Edinburgh Postnatal Depression Scale (comprises 10 questions that represent patients’ feelings in the last 7 days). The main outcome measure was to assess the association between intimate partner violence and depression. Results We recruited 158 women in each group. Both groups were matched in their demographic characters. Although emotional violence was reported prominently among women exposed to IPV 87.9% (139/158), it was not significantly reported in depressed women (P value 0.084). Physical and sexual violence were significantly reported among depressed women (P value 0.022 and 0.001, respectively). There was a significant difference between women exposed to violence and those who were not exposed to violence in the total depression scores (13.63 ± 5.47 and 10.65 ± 5.44, respectively with a p value < 0.001). Emotional (p value < 0.001) and sexual violence (mild and severe with p value of 0.026 and 0.002 respectively) had significant roles as risk factors for depression during pregnancy in single regression and after control of other confounders. Conclusion There was a strong association between intimate partner violence and depression during pregnancy.

Comparison of Human Thymus Gland between Young and Old Age

2021 ◽  
Vol 15 (6) ◽  
pp. 1907-1909
Author(s):  
Faiza Mehboob ◽  
Ponum Mirani ◽  
M. Kamran Ameer ◽  
Khurram Shabeer ◽  
Muhammad Ali Qamar ◽  
...  
Keyword(s):  
Connective Tissue ◽  
Old Age ◽  
Age Groups ◽  
Young Age ◽  
University Hospital ◽  
P Value ◽  
Old Patients ◽  
Human Thymus ◽  
Group I ◽  
Significant Difference

Aim: Study was conducted to examine the different parameters of human thymus glands of young and old patients and compare the findings between both age groups. Study Design: Comparative/observational study Place and Study: Study was conducted at Anatomy department of Nishtar Medical University Hospital, Multan for duration of six months from 15th January 2020 to 15th July 2020. Methods: Total 54 specimens of human thymus of 54 patients were enrolled in this study. All specimens were divided in to two groups I and II, Group I contains 27 patients with ages <30 years and group II with 27 patients having ages 45 to 60 years. All specimens were fixed in 10% formalin solution and then processed for paraffin embedding. Compare the different parameters such as thickness of interlobular connective tissue and thymic capsule, length and number of Hassal’s corpuscles between both groups. Data was analyzed by SPSS 24.0. Results: In group I 12 (44.44%) patients were ages <15 years and 15 (55.56%) patients were ages >15 years. In group 13 (48.15%) and 14 (51.85%) patients were ages <50 years and >50 years. There was a significant difference observed between both groups regarding thickness of interlobular connective tissue and thymic capsule, quantity and length of Hassal’s corpuscles with p-value <0.05. Conclusion: It is to be concluded that patients with young age had significantly less thickness of thymic capsule and interlobular connective tissue with more in number and decreasing size of Hassal’s corpuscles as compared to old age patients. Keywords: Human Thymus Glands, Young Age, Old Age

scholarly journals Healthy aging profile in octogenarians in Brazil

2016 ◽  
Vol 24 (0) ◽  
Author(s):  
Ana Cristina Viana Campos ◽  
Efigênia Ferreira e Ferreira ◽  
Andréa Maria Duarte Vargas ◽  
Lúcia Hisako Takase Gonçalves
Keyword(s):  
Older Adults ◽  
Decision Tree ◽  
Healthy Aging ◽  
Age Groups ◽  
Population Based ◽  
P Value ◽  
Age Group ◽  
Monthly Income ◽  
Tree Model ◽  
Socioeconomic Characteristics

ABSTRACT Objective: to identify the healthy aging profile in octogenarians in Brazil. Method: this population-based epidemiological study was conducted using household interviews of 335 octogenarians in a Brazilian municipality. The decision-tree model was used to assess the healthy aging profile in relation to the socioeconomic characteristics evaluated at baseline. All of the tests used a p-value < 0.05. Results: the majority of the 335 participating older adults were women (62.1%), were aged between 80 and 84 years (50.4%), were widowed (53.4%), were illiterate (59.1%), had a monthly income of less than one minimum wage (59.1%), were retired (85.7%), lived with their spouse (63.8%), did not have a caregiver (60.3%), had two or more children (82.7%), and had two or more grandchildren (78.8%). The results indicate three age groups with a healthier aging profile: older adults aged 80 to 84 years (55.6%), older adults aged 85 years and older who are married (64.9%), and older adults aged 85 and older who do not have a partner or a caregiver (54.2%). Conclusion: the healthy aging profile of octogenarians can be explained by age group, marital status, and the presence of a caregiver.

scholarly journals Risk Factors Associated with Ischemic Heart Diseases in Different Age Groups Patients of Tertiary Care Hospitals of Peshawar

2015 ◽  
Vol 1 (2) ◽  
pp. 3-9
Author(s):  
Riaz Gul ◽  
Sumaira Naz
Keyword(s):  
Risk Factors ◽  
Heart Diseases ◽  
Tertiary Care ◽  
Age Groups ◽  
Ischemic Heart ◽  
P Value ◽  
Age Group ◽  
Ischemic Heart Diseases ◽  
Sedentary Life ◽  
Tertiary Care Hospitals

Objectives:To determine different risk factors associated with ischemic heart diseases in different age group patients of tertiary care hospitals of Peshawar.Methodology:A cross sectional study conducted on 350 patients of different age groups presented with ischemic heart diseases in tertiary care hospitals of Peshawar. Study was conducted for duration of 3 months from December 2013 to February 2014. Non probability convenient sampling technique was used. Sample size was calculated using standard sample size calculator. Semi structured questionnaire was used as data collection tool. Patient’s record and investigations were used as adding tools. Standard definition was made for ischemic heart disease. Different modifiable and non-modifiable factors were assessed and were analyzed using SPSS version 16.Results:This study contains 350 patients in which female patients were 133(38%) and male were 217(62%).The mean age was 57.23±11.36 years. The age of the patients ranges from 22 to 80 years. The frequencies of risk factors were stress (73.1%) followed by hypertension (65.7%), sedentary life style (59.4%), family history (57.1%), smoking (50.6%), over weight and obese (39.1%), below normal HDL (30.3%), high LDL (29.1%), hypertriglyceridemia (28%), hypercholesterolemia (23.7%). 64.3% patients were presenting with acute IHD and 35.7% were with chronic IHD. Stress, HTN, DM and sedentary life style were found to be significantly associated with male gender (p- value <0.05). Age was divided into two groups, <45 years and >45 years. Stress, HTN, DM and hypercholesterolemia had a significant association with >45 years of age group. (P-value <0.05).Conclusion:Stress, HTN, DM, sedentary life styles were the major risk factors. And they were found to be more in male gender and in equal to more than 45 years of age group.

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