scholarly journals 289 Effects of supranutritional levels of dietary zinc oxide on zinc, copper, and iron metabolism in post-weaned pigs

2020 ◽  
Vol 98 (Supplement_3) ◽  
pp. 106-107
Author(s):  
Danyel Bueno Dalto ◽  
Frédéric Guay ◽  
Yan Martel-Kennes ◽  
Guylaine Talbot ◽  
Martin Lessard ◽  
...  
Keyword(s):  
Zinc Oxide ◽  
Serum Concentration ◽  
Treatment Effects ◽  
Experimental Period ◽  
Dietary Zinc ◽  
Weaned Pigs ◽  
Cu Content ◽  
Cu Deficiency ◽  
Fe Homeostasis ◽  
The Impact

Abstract This study evaluated the impact of supranutritional levels of dietary zinc oxide (ZnO) on zinc (Zn), copper (Cu), and iron (Fe) homeostasis in post-weaned pigs. One hundred twenty piglets were selected at d14 of age (5.65 ± 0.68 kg). At weaning (d21), they were fed a basal post-weaning diet (without antibiotics) supplemented (n = 40/treatment) with 100 mg/kg (low; LZn), 1000 mg/kg (medium; MZn) or 3000 mg/kg (high; HZn) of ZnO until d42. Dietary levels of Cu (130 mg/kg) and Fe (260 mg/kg) remained constant throughout the experimental period. Piglets were sacrificed at d21, d23, d35, and d42 of age (n = 10/treatment/d) for samples collection. Serum concentrations and total liver content of Zn and Cu were not different among treatments on d21 and d23 (P ≥ 0.10). For Zn, treatment effects were detected at d35 and d42 (P < 0.01) on both serum concentration and total Zn content in liver. For both parameters, values were greatest for HZn, intermediary for MZn, and lowest for LZn irrespective of ages in the two periods. For Cu, treatment effects were detected at d35 and d42 (P < 0.01) on both serum concentration and total Cu content in liver. For both parameters, values were greatest for LZn and MZn and lowest for HZn irrespective of ages. For Fe, no treatment effect was detected either on whole blood Fe concentrations (P = 0.81) or hemoglobin levels (P = 0.76). However, for total Fe content in liver, treatment effects were detected (P < 0.01). Values were greatest for LZn and lowest for HZn at d35 and d42 whereas for MZn they were intermediary at d35 and similar to LZn at d42 (P ≤ 0.01). In conclusion, supranutritional levels of dietary ZnO fed to piglets during 3 weeks post-weaning significantly impacted Zn, Cu, and Fe homeostasis. These results emphasise the potential risk of Cu deficiency as well as impairment in building body Fe reserves under long-term supranutritional supplementation of ZnO.

Dietary zinc oxide in weaned pigs — effects on performance, tissue concentrations, morphology, neutrophil functions and faecal microflora

1998 ◽  
Vol 64 (3) ◽  
pp. 225-231 ◽  
Author(s):  
Marianne Jensen-Waern ◽  
L. Melin ◽  
R. Lindberg ◽  
A. Johannisson ◽  
L. Petersson ◽  
...  
Keyword(s):  
Zinc Oxide ◽  
Dietary Zinc ◽  
Weaned Pigs ◽  
Tissue Concentrations ◽  
Faecal Microflora

scholarly journals Impact of zinc oxide, benzoic acid and probiotics on the performance and cecal microbiota of piglets

2021 ◽  
Vol 3 (1) ◽  
Author(s):  
Caio Abercio da Silva ◽  
Leonardo Aparecido Teixeira Bentin ◽  
Cleandro Pazinato Dias ◽  
Marco Aurélio Callegari ◽  
Vitor Barbosa Facina ◽  
...  
Keyword(s):  
Zinc Oxide ◽  
Benzoic Acid ◽  
Early Stage ◽  
Basal Diet ◽  
Experimental Period ◽  
Feed Additives ◽  
Feed Conversion ◽  
Bacterial Fermentation ◽  
Cecal Microbiota ◽  
The Impact

Abstract Background Intestinal health remains a key factor in animal production because it is essential for digestion, absorption and bacterial fermentation. Feed additives have been used to attenuate the weaning stress such as Zinc Oxide (ZnO) and benzoic acid (C7H6O2). The objective of this study was to evaluate the impact of of benzoic acid and probiotics (BA + P) on performance, diarrhea and cecal microbiota of piglets in the nursery phase (23 to 65 days). Results One hundred and sixty weaned piglets with an initial weight of 6.335 ± 0.698 kg and 23 days of age were submitted to four treatments: supplementation with 2500 ppm of Zinc oxide (ZnO), supplementation with a commercial blend of benzoic acid and probiotics (Bacillus licheniformis, Bacillus subtilis and Enterococcus faecium NCIMB 10415; Vevogut P®) (BA + P), supplementation with Zinc oxide plus benzoic acid and probiotics (ZnO + BA + P), and controls receiving only the basal diet without any supplementation. At 65 days of age, 32 piglets (n = 8 per treatment) were slaughtered for the evaluation of the cecal microbiota. Supplementation with ZnO and BA + P were associated with better feed conversion (P < 0.05) in the early stage (23 to 49 days) and with an improvement in all performance parameters over the entire experimental period. The occurrence of diarrhea was lower (P < 0.05) in the BA + P group. The 4 most abundant phyla along with unclassified bacteria represented 93% of all sequences. Firmicutes dominated the cecal microbiota of all groups, followed by Bacteroidetes. Richness represented by the observed number of genera and by the Chao index were statistically lower in ZnO and ZnO + BA + P supplemented animals compared to controls. The beta diversity analysis that compares similarities between bacterial communities demonstrated formation of two distinct clusters containing samples with and without supplementation with ZnO, confirming a strong influence of ZnO on the intestinal microbiota. Conclusion The use of Benzoic acid with probiotics yields similar performance results with lower impact on the gut microbiota compared to ZnO, and it should be considered as a potential alternative in swine production.

scholarly journals Effect of rearing environment and dietary zinc oxide on the response of group-housed weaned pigs to enterotoxigenic Escherichia coli O149 challenge

animal ◽  
2011 ◽  
Vol 5 (8) ◽  
pp. 1170-1178 ◽  
Author(s):  
R.D. Slade ◽  
I. Kyriazakis ◽  
S.M. Carroll ◽  
F.H. Reynolds ◽  
I.J. Wellock ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Zinc Oxide ◽  
Enterotoxigenic Escherichia Coli ◽  
Dietary Zinc ◽  
Weaned Pigs ◽  
Rearing Environment

Soil and plant factors limiting the availability of copper to a beef suckler herd

1983 ◽  
Vol 101 (1) ◽  
pp. 39-46 ◽  
Author(s):  
S. C. Jarvis ◽  
A. R. Austin
Keyword(s):  
Serum Concentration ◽  
Severe Anaemia ◽  
High Concentration ◽  
Grazing Season ◽  
Cu Content ◽  
Cu Deficiency ◽  
Per Se ◽  
Beef Suckler

SUMMARYHypocuprosis has been diagnosed for 4 years in calves of a beef suckler herd at Warren Farm, Berkshire. The copper (Cu) contents and distribution in the soil at that site, as well as changes in herbage Cu throughout the 1979 grazing season, were examined. The herbage Cu concentration was always less than 7·5 μg/g and decreased markedly to 3·0 μg/g during July. Serum Cu contents of both untreated cows and untreated calves also decreased markedly, but at a much earlier stage than the decrease in herbage concentration. One untreated calf developed severe anaemia, but recovered when treated with Cu Ca EDTA. Although changes in the coefficient of absorption of dietary Cu were caused by changes in S and Mo contents, the calculated availability of Cu was dominated by the Cu content per se. Thus the calculated availability remained relatively high during the period when serum concentration decreased.The decrease in serum Cu may have occurred as the result of a differing availability of Cu in ensiled and grazed herbages. However, coincident with the decrease in serum Cu was a high concentration of Fe in the grazed herbage which was largely associated with the surfaces of the leaves. It is therefore possible that the development of Cu deficiency immediately after the animals started to graze was precipitated either through an interaction between Cu and Fe in the animal, or because of a reduced availability of Cu through an interaction with ingested soil.

scholarly journals The impact of high dietary zinc oxide on the development of the intestinal microbiota in weaned piglets

2013 ◽  
Vol 87 (2) ◽  
pp. 416-427 ◽  
Author(s):  
Ingo C. Starke ◽  
Robert Pieper ◽  
Konrad Neumann ◽  
Jürgen Zentek ◽  
Wilfried Vahjen
Keyword(s):  
Zinc Oxide ◽  
Intestinal Microbiota ◽  
Weaned Piglets ◽  
Dietary Zinc ◽  
The Impact

scholarly journals 130 Young Scholar Presentation: Can exogenous carbohydrase supplementation to higher-fiber diets improve gut function, microbiota, and growth performance of weaned pigs?

2019 ◽  
Vol 97 (Supplement_2) ◽  
pp. 76-76
Author(s):  
Qingyun Li ◽  
Nicholas K Gabler ◽  
Eric R Burrough ◽  
Crystal L Loving ◽  
Stephan Schmitz-Esser ◽  
...  
Keyword(s):  
Growth Performance ◽  
Bacterial Infections ◽  
Experimental Period ◽  
Nutrient Utilization ◽  
Enterotoxigenic Escherichia Coli ◽  
Gut Health ◽  
Weaned Pigs ◽  
Young Pigs ◽  
Gut Function ◽  
The Impact

Abstract There is increasing interest in feeding higher-fiber coproducts to weaned pigs due to their potential benefits on gut function and microbiota. However, young pigs are not efficient at utilizing fibrous coproducts. Exogenous carbohydrases can be used to improve nutrient utilization and growth of pigs fed higher levels of coproducts. Previous results regarding the impact of carbohydrases on performance in pigs have been inconsistent, thus a better understanding of associated mechanisms is needed. Using 460 weaned pigs (6.4 ± 0.1 kg), our first study showed that a carbohydrase enzyme blend (EB) improved ADG of weaned pigs fed higher-fiber diets (with added DDGS and wheat middlings) over a 28-d experimental period (P < 0.05). Pigs fed EB-supplemented diets had lower urinary lactulose:mannitol ratio, decreased plasma IL-8 concentration, and greater ileal CLDN3 (claudin 3) mRNA abundance, compared with those fed diets without EB (P < 0.05). These changes may partly explain the improved growth, providing mode of action evidence for carbohydrase in improving performance of weaned pigs. Carbohydrases may also exert prebiotic effects through release of oligosaccharides from fiber degradation. Thus, carbohydrases and dietary fiber may improve disease resilience of young pigs against bacterial infections, for example, enterotoxigenic Escherichia coli (ETEC) induced post-weaning diarrhea. Our second study evaluated the impact of soluble versus insoluble fiber with or without carbohydrases in newly weaned pigs (n = 60; 6.9 ± 0.07 kg) challenged with F18 ETEC. A diet containing a soluble and highly fermentable fiber from sugar beet pulp with added carbohydrases improved (P < 0.05) ADG, tended to increase (P < 0.10) ileal OCLN (occludin) mRNA, increased (P < 0.05) colonic OCLN mRNA, and tended to decrease (P < 0.10) ileal Escherichia-Shigella compared with ETEC-challenged control. Collectively, appropriate use of exogenous carbohydrases in higher-fiber diets (with the right type and amount of enzyme substrate) is promising in improving gut health and growth performance in weaned pigs.

scholarly journals The Effects of Feed Color on Broiler Performance between Day 1 and 21

Animals ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 1511
Author(s):  
Joseph P. Gulizia ◽  
Kevin M. Downs
Keyword(s):  
Body Weight ◽  
Weight Gain ◽  
Treatment Effects ◽  
Body Weight Gain ◽  
Experimental Period ◽  
Feed Consumption ◽  
Feed Conversion ◽  
Broiler Performance ◽  
Average Body ◽  
Average Body Weight

Two trials were conducted to determine feed color effects on broiler performance. A completely randomized design was used. Trial 1 included four treatments: control (complete broiler starter diet), red, green, and blue; and Trial 2 included four treatments: control, orange, yellow, and purple. Each trial had 4 treatments with 4 replicates (60 birds/treatment) fed to 240 male Cobb 500 broilers during a 21 d grow out. Data were analyzed using the GLM procedure. In Trial 1, there were no treatment effects on average body weight, body weight gain, and feed consumption (p > 0.05). Adjusted feed conversion for control (1.23) was less than red (1.27; p = 0.001) and green (1.26; p = 0.009), with blue (1.25; p = 0.056) tending to be different during the experimental period. In Trial 2, there were no treatment effects on average body weight, feed consumption, and adjusted feed conversion during this study (p > 0.05). Body weight gain between d 1 to 14 for purple (490.78 g/bird) was more than orange (467 g/bird; p = 0.013) and yellow (461 g/bird; p= 0.004), with control (474 g/bird; p = 0.052) tending to be different. Results indicate that these feed colors had some, albeit limited, influence on broiler performance parameters.

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