Mayo Clinic Neurology Board Review

2021 ◽  
Keyword(s):  
Mayo Clinic ◽  
High Yield ◽  
Clinical Aspects ◽  
Clinical Neurology ◽  
Certification Examination ◽  
Board Examination ◽  
Current Therapies ◽  
Essential Knowledge ◽  
Board Review ◽  
First Time

Neurology is an exciting and rapidly expanding area of medicine. This new edition of Mayo Clinic Neurology Board Review is designed to assist both physicians-in-training who are preparing for the initial American Board of Psychiatry and Neurology (ABPN) certification examination and neurologists who are preparing for recertification. Trainees and other physicians in related specialties such as psychiatry, neurosurgery, or physiatry may also find this book useful in preparation for their own certification examinations. While erring on the side of thoroughness, Mayo Clinic Neurology Board Review, Second Edition, is not intended to replace an in-depth textbook or serve as a guide to the most current therapies. Instead, this book provides a core of essential knowledge of both basic and clinical aspects of neurology. The emphasis is on clinical knowledge related to diagnostic and therapeutic approaches to patient management. In addition, this text has an expansive array of illustrations, pathology, and radiologic images. There are different needs for those who are taking the initial board examination and for those who are recertifying. The first section covers basic sciences and psychiatry, and the remaining portion covers clinical neurology. It is intended that people taking the board examination for the first time would benefit from reviewing all chapters, whereas those recertifying may wish to mainly focus on the clinical section. Throughout the book, high-yield facts and questions have been included for your review.

Psychiatry Board Review

2017 ◽  
Keyword(s):  
Clinical Practice ◽  
Treatment Strategies ◽  
The United States ◽  
Certification Examination ◽  
Board Examination ◽  
Diagnostic And Statistical Manual ◽  
Dsm 5 ◽  
Psychotherapeutic Techniques ◽  
Board Review

The field of psychiatry is rapidly evolving, specifically in the areas of psychopharmacology, psychotherapeutic strategies, and the classification of many major psychiatric disorders with the implementation of the Diagnostic and Statistical Manual of Mental Disorders: DSM-5 in 2013. A new board review textbook is imperative to address these changes in order to prepare board-eligible psychiatrists for the certification examination as well as for clinical practice in general. Additionally, the American Board of Psychiatry and Neurology is in the process of phasing in the DSM-5 criteria to the board examination, such that by 2017 the examination material will exclusively reflect the new manual. The book is aimed primarily at board-eligible psychiatrists preparing for their Initial certification in psychiatry. It will be a useful study tool for psychiatrists renewing certification as well, which in the United States is required every ten years. Furthermore the text will also be a useful reference for all psychiatrists in clinical practice to familiarize themselves with the new diagnostic classifications of DSM-5, the latest psychopharmacologic treatment strategies, and psychotherapeutic techniques.

Pediatric Anesthesiology

2015 ◽  
Keyword(s):  
Multiple Choice ◽  
High Yield ◽  
Multiple Choice Questions ◽  
Certification Examination ◽  
Board Exam ◽  
Reading Efficiency ◽  
Board Review

Pediatric Anesthesiology: A Comprehensive Board Review is a high-yield, streamlined study aid. It contains more than 800, realistic, multiple-choice questions tailored to the keywords in the outline of the Pediatric Anesthesiology Certification Examination published by the American Board of Anesthesiology (ABA). To maximize reading efficiency, annotated answers are followed by bulleted key facts and key references. With this book as guide, readers will be able to efficiently prepare for the written primary certification pediatric anesthesiology board exam.

High-Yield Board Review Topics

2013 ◽  
Author(s):  
Kaveh Aslani ◽  
Richard Han ◽  
Dominic Monterosso
Keyword(s):  
Board Certification ◽  
High Yield ◽  
Certification Examination ◽  
Board Review

Chapter 21 contains 60 topics frequently missed by examinees sitting for the board certification examination in anesthesiology.

Mayo Clinic Critical and Neurocritical Care Board Review

2019 ◽  
Keyword(s):  
Critical Care ◽  
Intensive Care ◽  
Nursing Staff ◽  
Mayo Clinic ◽  
Neurocritical Care ◽  
Multidisciplinary Care ◽  
Respiratory Care ◽  
Board Examination ◽  
Specialized Care ◽  
Board Review

Physicians have cared for acutely ill patients throughout history; after the devastating poliomyelitis epidemics of the 1950s, a new specialty emerged. Initially, respiratory care units were created for these severely affected patients, but soon they were transformed into intensive care units (ICUs). Trauma units and transplant units soon followed. Specialized care for patients with acute neurologic and neurosurgical disease occurred in parallel with these developments, but many of the early neuroscience ICUs were redesigned wards for neurosurgical or neurologic patients. Specialized physicians and nursing staff delivered multidisciplinary care, recognizing that no one group could function well alone. It was inevitable that critical care for the sickest patient was the only option to give them a fighting chance to survive. Currently, neurocritical care board examination combines neurocritical care with general intensive care, and questions are equally divided between the two. It is therefore appropriate to combine both areas of expertise in one single volume. The chapters correspond with the key disorders suggested by UCNS to assist in preparation for the examination. As expected, this book is not only detailed in basic pathophysiology but also presents major disorders and syndromes and their management. Because it has unprecedented full coverage of acute neurology, this book is equally useful as a preparation for the critical care medicine board examination.

The Smoulder Stream of Cigarettes / Zur Kenntnis des Glimmstromes von Cigaretten

1965 ◽  
Vol 3 (2) ◽  
Author(s):  
F. Seehofer ◽  
W. Schulz
Keyword(s):  
Moisture Content ◽  
Spatial Position ◽  
High Yield ◽  
Physical Conditions ◽  
Moisture Contents ◽  
Cigarette Paper ◽  
First Time

AbstractThe phenomenon of the smoulder stream flowing through the cigarette during smouldering and during the puff intervals is demonstrated for the first time and its dependence upon physical conditions is examined. The volume of the smoulder stream can amount up to 180 ml per cigarette. Increasing draw resistance of the cigarette and augmenting moisture content of the tobacco as well as perforation of the cigarette paper have a decreasing effect on volume and velocity of the smoulder stream. The porosity of the cigarette paper has no perceptible influence. The spatial position of the cigarette affects volume and velocity of the smoulder stream. The influence exercised by the smoulder stream on the yields of total condensate, nicotine, phenols, aldehydes, and acroleine when the cigarette tip is open during the puff intervals is determined. When the moisture contents of the tobacco were extremely high, yield decreases reaching 50 % could be observed.

Iridium-Catalyzed Silylation of C-H bonds in Unactivated Arenes: A Sterically-Encumbered Phenanthroline Ligand Accelerates Catalysis Enabling New Reactivity

2019 ◽  
Author(s):  
Caleb Karmel ◽  
Zhewei Chen ◽  
John Hartwig
Keyword(s):  
High Activity ◽  
Functional Group ◽  
Activity Analysis ◽  
High Reactivity ◽  
High Yield ◽  
Phen Ligand ◽  
Mechanistic Studies ◽  
Phenanthroline Ligand ◽  
First Time ◽  
New System

We report a new system for the silylation of aryl C-H bonds. The combination of [Ir(cod)(OMe)]<sub>2</sub> and 2,9-Me<sub>2</sub>-phenanthroline (2,9-Me<sub>2</sub>phen) catalyzes the silylation of arenes at lower temperatures and with faster rates than those reported previously, when the hydrogen byproduct is removed, and with high functional group tolerance and regioselectivity. Inhibition of reactions by the H<sub>2</sub> byproduct is shown to limit the silylation of aryl C-H bonds in the presence of the most active catalysts, thereby masking their high activity. Analysis of initial rates uncovered the high reactivity of the catalyst containing the sterically hindered 2,9-Me<sub>2</sub>phen ligand but accompanying rapid inhibition by hydrogen. With this catalyst, under a flow of nitrogen to remove hydrogen, electron-rich arenes, including those containing sensitive functional groups, undergo silylation in high yield for the first time, and arenes that underwent silylation with prior catalysts react over much shorter times with lower catalyst loadings. The synthetic value of this methodology is demonstrated by the preparation of key intermediates in the synthesis of medicinally important compounds in concise sequences comprising silylation and functionalization. Mechanistic studies demonstrate that the cleavage of the aryl C-H bond is reversible and that the higher rates observed with the 2,9-Me<sub>2</sub>phen ligand is due to a more thermodynamically favorable oxidative addition of aryl C-H bonds.

scholarly journals Bacterial cellulose spheroids as building blocks for 3D and patterned living materials and for regeneration

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Joaquin Caro-Astorga ◽  
Kenneth T. Walker ◽  
Natalia Herrera ◽  
Koon-Yang Lee ◽  
Tom Ellis
Keyword(s):  
Bacterial Cellulose ◽  
Building Blocks ◽  
Genetically Engineered ◽  
High Yield ◽  
Synthetic Materials ◽  
Chemical Inputs ◽  
First Time ◽  
3D Shapes ◽  
Promising Avenue ◽  
Living Materials

AbstractEngineered living materials (ELMs) based on bacterial cellulose (BC) offer a promising avenue for cheap-to-produce materials that can be programmed with genetically encoded functionalities. Here we explore how ELMs can be fabricated in a modular fashion from millimetre-scale biofilm spheroids grown from shaking cultures of Komagataeibacter rhaeticus. Here we define a reproducible protocol to produce BC spheroids with the high yield bacterial cellulose producer K. rhaeticus and demonstrate for the first time their potential for their use as building blocks to grow ELMs in 3D shapes. Using genetically engineered K. rhaeticus, we produce functionalized BC spheroids and use these to make and grow patterned BC-based ELMs that signal within a material and can sense and report on chemical inputs. We also investigate the use of BC spheroids as a method to regenerate damaged BC materials and as a way to fuse together smaller material sections of cellulose and synthetic materials into a larger piece. This work improves our understanding of BC spheroid formation and showcases their great potential for fabricating, patterning and repairing ELMs based on the promising biomaterial of bacterial cellulose.

scholarly journals A Novel and Efficient High-Yield Method for Preparing Bacterial Ghosts

Toxins ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 420
Author(s):  
Yi Ma ◽  
Liu Cui ◽  
Meng Wang ◽  
Qiuli Sun ◽  
Kaisheng Liu ◽  
...  
Keyword(s):  
Large Scale ◽  
Expression System ◽  
High Yield ◽  
Wild Type ◽  
High Quality ◽  
Efficient Protection ◽  
Bacterial Ghosts ◽  
Cell Envelopes ◽  
Extracellular Structures ◽  
First Time

Bacterial ghosts (BGs) are empty cell envelopes possessing native extracellular structures without a cytoplasm and genetic materials. BGs are proposed to have significant prospects in biomedical research as vaccines or delivery carriers. The applications of BGs are often limited by inefficient bacterial lysis and a low yield. To solve these problems, we compared the lysis efficiency of the wild-type protein E (EW) from phage ΦX174 and the screened mutant protein E (EM) in the Escherichia coli BL21(DE3) strain. The results show that the lysis efficiency mediated by protein EM was improved. The implementation of the pLysS plasmid allowed nearly 100% lysis efficiency, with a high initial cell density as high as OD600 = 2.0, which was higher compared to the commonly used BG preparation method. The results of Western blot analysis and immunofluorescence indicate that the expression level of protein EM was significantly higher than that of the non-pLysS plasmid. High-quality BGs were observed by SEM and TEM. To verify the applicability of this method in other bacteria, the T7 RNA polymerase expression system was successfully constructed in Salmonella enterica (S. Enterica, SE). A pET vector containing EM and pLysS were introduced to obtain high-quality SE ghosts which could provide efficient protection for humans and animals. This paper describes a novel and commonly used method to produce high-quality BGs on a large scale for the first time.

scholarly journals Stable and Oriented Liquid Crystal Droplets Stabilized by Imidazolium Ionic Liquids

Molecules ◽  
2021 ◽  
Vol 26 (19) ◽  
pp. 6044
Author(s):  
Efthymia Ramou ◽  
Guilherme Rebordão ◽  
Susana I. C. J. Palma ◽  
Ana C. A. Roque
Keyword(s):  
Ionic Liquids ◽  
Liquid Crystal ◽  
Soft Matter ◽  
Sodium Dodecyl ◽  
High Yield ◽  
Molecular Features ◽  
Surface Active ◽  
State Of Matter ◽  
First Time ◽  
Sds Surfactant

Liquid crystals represent a fascinating intermediate state of matter, with dynamic yet organized molecular features and untapped opportunities in sensing. Several works report the use of liquid crystal droplets formed by microfluidics and stabilized by surfactants such as sodium dodecyl sulfate (SDS). In this work, we explore, for the first time, the potential of surface-active ionic liquids of the imidazolium family as surfactants to generate in high yield, stable and oriented liquid crystal droplets. Our results show that [C12MIM][Cl], in particular, yields stable, uniform and monodisperse droplets (diameter 74 ± 6 µm; PDI = 8%) with the liquid crystal in a radial configuration, even when compared with the standard SDS surfactant. These findings reveal an additional application for ionic liquids in the field of soft matter.

scholarly journals Ebola in Africa - Discoveries in the past decade

2002 ◽  
Vol 7 (3) ◽  
pp. 33-36 ◽  
Author(s):  
R R Arthur
Keyword(s):  
Laboratory Diagnosis ◽  
Communicable Diseases ◽  
Control Measures ◽  
Clinical Aspects ◽  
Haemorrhagic Fever ◽  
The Past ◽  
Republic Of The Congo ◽  
The Republic ◽  
And Control ◽  
First Time

Within the past decade, Ebola haemorrhagic fever (EHF) has been recognised for the first time in four countries. Our understanding of the epidemiology, clinical aspects, laboratory diagnosis and control measures for EHF has improved considerably as a result of the outbreaks in these countries and the re-emergence that has occurred in another. The coordinated international responses to several of the large EHF outbreaks serve as models for controlling epidemics of other communicable diseases. This report is a chronological overview of the EHF outbreaks in Africa during the past decade, including the recent epidemics in Gabon and the Republic of the Congo, and highlights new discoveries and some of the remaining challenges.

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