scholarly journals Secondary Metabolites ofHypericum leptophyllumHochst., an Endemic Turkish Species

2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
Necdet Camas ◽  
Jolita Radusiene ◽  
Zydrunas Stanius ◽  
Omer Caliskan ◽  
Cuneyt Cirak

In the present study, the presence of the phloroglucinol derivative hyperforin, the naphthodianthrones hypericin and pseudohypericin, the phenylpropane chlorogenic acid and the flavonoids rutin, hyperoside, kaempferol, isoquercetine, quercitrine, and quercetine was investigated inHypericum leptophyllumHochst., an endemic Turkish species for the first time. The aerial parts representing a total of 30 individuals were collected at full flowering and dissected into floral, leaf, and stem tissues. After being dried at room temperature, the plant materials were assayed for secondary metabolite concentrations by HPLC. Aerial plant parts accumulated chlorogenic acid, hyperoside, isoquercetine, quercitrine, and quercetine, but they did not accumulate hyperforin, hypericin, pseudohypericin, rutin, and kaempferol. Accumulation levels of the detected compounds varied with plant tissues. Such kind of data could be useful for elucidation of the chemotaxonomical significance of the corresponding compounds and phytochemical evaluation of this endemic species.

2008 ◽  
Vol 3 (10) ◽  
pp. 1934578X0800301 ◽  
Author(s):  
Necdet Çamaş ◽  
Jolita Radušienė ◽  
Ali Kemal Ayan ◽  
Cüneyt Çırak ◽  
Valdimaras Janulis ◽  
...  

The present study was conducted to determine the variation in the content of hyperforin, hypericin and pseudohypericin in Hypericum triquetrifolium Turra growing wild in four locations of Turkey. The aerial parts, representing a total of 30 individuals, were collected at full flowering and dissected into floral, leaf and stem tissues. After drying at room temperature, the plant materials were assayed for their chemical contents by HPLC. The populations varied significantly in chemical contents. Hyperforin content ranged from 0.05 to 0.56 mg/g, hypericin from 0.74–1.98 mg/g, and pseudohypericin from 0.72–2.26 mg/g, dry weight. Among the different plant parts, the flowers were found to be the principle organ for hyperforin accumulation, while hypericin and pseudohypericin were accumulated mainly in leaves. Such kinds of data could be useful for optimizing the processing methodology of wild-harvested plant material and phytochemical evaluation of H. triquetrifolium.


2010 ◽  
Vol 5 (6) ◽  
pp. 1934578X1000500 ◽  
Author(s):  
Cüneyt Çırak ◽  
Jolita Radušienė ◽  
Valdimaras Janulis ◽  
Liudas Ivanauskas

The phloroglucinol derivative hyperforin, the naphthodianthrones hypericin and pseudohypericin, the phenylpropane chlorogenic acid, and the flavonoids rutin, hyperoside, apigenin-7- O-glucoside, kaempferol, quercitrin, quercetin and amentoflavone were investigated in Hypericum confertum growing wild in Turkey. After drying at room temperature, the plant materials were assayed for secondary metabolite concentrations by HPLC. All the listed compounds were detected at various levels. This is the first report on the chemistry of H. confertum.


2011 ◽  
Vol 6 (11) ◽  
pp. 1934578X1100601 ◽  
Author(s):  
Jaroslaw Moldoch ◽  
Barbara Szajwaj ◽  
Milena Masullo ◽  
Lukasz Pecio ◽  
Wieslaw Oleszek ◽  
...  

A new C-6 flavone glycoside (6), together with seven known compounds, cryptochlorogenic acid (1), chlorogenic acid (2), 2- O- trans-caffeoylhydrocitric acid (3), isovitexin 7-β-D-glucopyranoside (4), 7,4′-dihydroxy-5-methoxyflavone-6- C-β-D-glucopyranoside (5), 3,5- O-dicaffeoylquinic acid (7) and 4,5- O-dicaffeoylquinic acid (8), were isolated from the aerial parts of Knautia arvensis. Their structures were elucidated by extensive spectroscopic methods including 1D- (1H, 13C and TOCSY) and 2D-NMR (DQF-COSY, HSQC, HMBC) experiments, as well as ESIMS analysis. Compounds 1, 3-5 and 8 are reported for the first time in Knautia arvensis.


2003 ◽  
Vol 58 (9-10) ◽  
pp. 704-707 ◽  
Author(s):  
Rilka Taskova ◽  
Maya Mitova ◽  
Bozhanka Mikhova ◽  
Helmut Duddeck

AbstractTwo flavonoid aglycons, eight flavonoid glycosides, chlorogenic acid and syringin were isolated from aerial parts of Carthamus lanatus. Isorhamnetin 3-O-β-ᴅ-glucoside and chlorogenic acid were found for the first time in the genus Carthamus and respectively, quercimeritrin, astragalin, kaempferol 3-O-β-ᴅ-sophoroside and syringin in the species. The ethyl acetate fraction of the methanol extract exhibited a higher antioxidant activity than the butanol fraction measured by the α,α-diphenyl-β-picrazylhydrazyl (DPPH) free radical scavenging assay. Cytotoxicity and antioxidant activities of the main constituent, luteolin 7-O-β-D-glucoside, were evaluated.


Antibiotics ◽  
2021 ◽  
Vol 10 (2) ◽  
pp. 148
Author(s):  
Marco Masi ◽  
Emanuela Roscetto ◽  
Alessio Cimmino ◽  
Maria Rosaria Catania ◽  
Giuseppe Surico ◽  
...  

Chiliadenus lopadusanus Brullo is an Asteraceae plant species endemic to Lampedusa island, the largest island of the Pelage archipelago, Italy. The organic extract of its whole aerial parts, showing antibiotic activity against Staphylococcus aureus and Acinetobacter baumannii, wasfractionated employing bioguided purification procedures affording three main farnesane-type sesquiterpenoids. They were identified by spectroscopic methods (NMR and ESIMS data) as the (E)-3,7,11-trimethyldodeca-1,6,10-triene-3,9-diol, (E)-10-hydroxy-2,6,10-trimethyldodeca-2,6,11- trien-4-one and (E)-10-hydroxy-2,6,10-trimethyl-dodeca-6,11-dien-4-one, commonly named 9-hydroxynerolidol, 9-oxonerolidol, and chiliadenol B, respectively. These three sesquiterpenes, isolated for the first time from C. lopadusanus, were tested on methicillin-resistant S. aureus and A. baumannii showing antibacterial and antibiofilm activities. This plant could be used as a source to isolate secondary metabolites as potential new antibiotics.


2017 ◽  
Vol 4 (7) ◽  
pp. 19-23
Author(s):  
Rumi Kotoky ◽  
Siddhartha Pratim Saikia ◽  
Bithika Chaliha ◽  
Subhan Chandra Nath

The compositional analysis of essential oil content in inflorescence and vegetative aerial parts of Elsholtzia blanda Benth. (Lamiales: Lamiaceae) growing wild in Meghalaya,North-East India were studied by GC and GC-MS. A total of 30 and 17 components representing 96.9%-98.3% and 92.6%-92.8% of the total oils from the inflorescence and vegetative aerial parts, respectively, were identified. Significant difference in composition of oils were observed between the two plant parts; 15 components detected in the oil of inflorescence were lacking in the oil of vegetative aerial parts, while two components present in the oil of vegetative aerial parts were absent in the inflorescence oil. Linalool was the major component in oils of both inflorescence (77.3%-80.2%) and vegetative aerial parts (57.9%-62.9%). Trans- linalool oxide (8.4%-9.9%), cis-linalool oxide (8.3%-9.3%) and 3,7-dimethyl-1,5-octadiene-3,7-diol (4.7%-5.1%) were however found in higher amount in the oil of vegetative aerial parts compared to inflorescence. For the first time the composition of oil in the inflorescence part has been reported in this communication while the oil from vegetative aerial parts containing linalool as the major component (44.9%) was although reported earlier but comparatively higher percentage of same was observed in vegetative aerial part (57.9%-62.9%) and inflorescence (77.3%-80.2%) in the present investigation with the plants from Meghalaya, India.


2001 ◽  
Vol 14 (5) ◽  
pp. 599-608 ◽  
Author(s):  
Karen Cornelis ◽  
Tita Ritsema ◽  
Jaap Nijsse ◽  
Marcelle Holsters ◽  
Koen Goethals ◽  
...  

Rhodococcus fascians is a plant-pathogenic bacterium that causes malformations on aerial plant parts, whereby leafy galls occur at axillary meristems. The colonization behavior on Nicotiana tabacum and Arabidopsis thaliana plants was examined. Independent of the infection methods, R. fascians extensively colonized the plant surface where the bacteria were surrounded by a slime layer. R. fascians caused the collapse of epidermal cells and penetrated intercellularly into the plant tissues. The onset of symptom development preceded the extensive colonization of the interior. The meristematic regions induced by pathogenic strain D188 were surrounded by bacteria. The nonpathogenic strain, D188-5, colonized the exterior of the plant equally well, but the linear plasmid (pFiD188) seemed to be involved in the penetration efficiency and colonization of tobacco tissues.


Planta Medica ◽  
2021 ◽  
Author(s):  
Karolina Grabowska ◽  
Paweł Żmudzki ◽  
Dagmara Wróbel-Biedrawa ◽  
Irma Podolak

AbstractThe content of ursolic acid and oleanolic acid was determined in different plant parts of two Glechoma species, G. hederacea and G. hirsuta. To achieve optimal extraction conditions of ursolic acid and oleanolic acid from plant material, several methods including maceration, heat reflux, Soxhlet, and ultrasonic extraction, as well as various solvents (methanol, dichloromethane, ethyl acetate), were investigated and compared.For the simultaneous quantification of pentacyclic triterpenes in extracts from Glechoma sp., an UPLC-MS/MS was developed and validated. The method exhibited good linearity, precision, and recovery, and it also was simple, specific, and fast. We developed the method for future application in the quality control of plant materials and botanical extracts containing ursolic acid and oleanolic acid. With regard to the triterpene constituents, both G. hederacea and G. hirsuta can be used equally, and the aboveground parts of both species, but the leaves especially, are abundant sources of ursolic acid (7.1 – 7.5 mg/g dry weight [DW]). Dichloromethane as an extractant provided the best extraction efficiency as well as selectivity to obtain Glechoma extracts rich in triterpenes as compared to methanol and ethyl acetate, regardless of the particular extraction technique. Dry dichloromethane extracts from aerial parts of Glechoma sp. obtained by the heat reflux method resulted in products with a high content of UA (17 – 25% w/w) are considered to be convenient and rich sources of this compound.


Author(s):  
Kamini Singh ◽  
Deepika Sharma ◽  
Gupta Rs

Barleria prionitis is a famous perennial plant commonly known as porcupine flower or Vajradanti. It is a shrub with yellow flowers and two flat seeds shielded with matted hairs, inhabit most parts of India. Various parts of the plant such as leaves, roots, aerial parts, flowers, and stems are used in the traditional system of medicine. Conventionally, various infusions are prepared using the plant parts and utilized for the treatment of different kinds of diseases. Owing to its incredible odontalgic property, it is extensively used in treating bleeding gums and toothache. From the pharmacological point, the plant has been effectively screened for antibacterial, antifungal, antiviral, anti-inflammatory, antifertility, antioxidant, enzyme inhibitory, hepatoprotective, antihypertensive, anticancer, and anticataract activities. Compounds such as tannins, saponins, glycosides, phenolic acids, phytosterols, and terpenes have been identified in the plant. The plant contains some specific compounds such as barlenoside, barlerine, acetylbarlerine, and balarenone and some common secondary metabolites such as lupeol, β-sitosterol, vanillic acid, and syringic acid. This review provides morphological, ethnomedical, pharmacological, and phytochemical data of the plant B. prionitis.


2011 ◽  
Vol 6 (9) ◽  
pp. 1934578X1100600 ◽  
Author(s):  
Avni Hajdari ◽  
Behxhet Mustafa ◽  
Chlodwig Franz ◽  
Johannes Novak

The aerial parts and roots of Betonica officinalis were collected from three localities characterized by different ecological conditions to study the natural variability of the chemical composition of the essential oils in this plant. The leaves and inflorescences were collected during the flowering time, whereas the roots were collected at the end of the vegetative period. The plant material was dried at room temperature. The essential oils were obtained by micro-steam hydrodistillation and analyzed using gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). Overall, 69 constituents were identified in all localities and plant parts. The main compositions of the leaves in all localities were α-pinene, 1-octen-3-ol, β-bourbonene, ( E)-caryophyllene and germacrene D. The essential oil of the inflorescences was characterized by these main constituents: α-pinene, ( E)-caryophyllene and trans-β-farnesene. In all localities, the percentages of α-pinene and ( E)-caryophyllene were higher in the inflorescences than in the leaves, whereas nonane was the main constituent in the roots.


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