Target area for Nova Upgrade: containing ignition and beyond

2002 ◽  
Author(s):  
M.T. Tobin ◽  
J.R. Smith ◽  
D. Campbell ◽  
D.K. Wong ◽  
J.A. Sullivan ◽  
...  
Keyword(s):  
Target Area

FIRST RECORD OF MANTIDS (MANTODEA: INSECTA) FROM INDIA

2018 ◽  
Vol 24 (1) ◽  
Author(s):  
SHVETA PATEL ◽  
RAJENDRA SINGH
Keyword(s):  
Uttar Pradesh ◽  
First Record ◽  
Target Area ◽  
Extensive Survey ◽  
First Time

Extensive survey of mantids in the northeastern Uttar Pradesh was conducted. Two mantid species were recorded for the first time from the target area, viz.: Pyrgomantis pallida, 1917 and Bactromantis mexicana.

PERAN AIR REBUSAN DAUN SALAM (SYZGIUM POLYANTHUM) DALAM MENURUNKAN KADAR ASAM URAT

2016 ◽  
Vol 5 (2) ◽  
pp. 83-91
Author(s):  
Miftafu Darussalam ◽  
Dwi Kartika Rukmi
Keyword(s):  
Uric Acid ◽  
Vascular Inflammation ◽  
Vascular Lesion ◽  
Wilcoxon Test ◽  
Test Time ◽  
Control Group ◽  
Target Area ◽  
Bioactive Substances ◽  
Control Group Design ◽  
Boiled Water

Background: Uric acid is a final product or a waste that is resulted from the metabolism of purines. A high level of uric acid (hyperuricemia) will cause several health problems, such as vascular inflammation, smooth muscle proliferation, and vascular lesion in kidneys. The syzygium polyanthum leaves contain bioactive substances that may affect the level of uric acid in blood. Objective: This study aimed to determine the influence of boiled water of syzygium polyanthum leaves to the changes of uric acid levels in the target area of Puskesmas Pandak 1 Bantul. Methods: This study employed pre- and post-test without control group design. The population consisted of all patients with hyperuricemia in the target area of Puskesmas Pandak 1 Bantul. Sample was selected with a concecutive sampling, gaining a total number of 24 respondents. Data were analyzed with the Wilcoxon test. The dose of boiled water of syzygium polyanthum leaves intake was 0.36g/ KgBW, once a day for 14 days. Result: This research showed that the boiled water of syzygium polyanthum leaves decreased hyperuricemia (uric acid levels), along with the significancy value of 0.009 (p <0.05). At the pre-test time, the average level of uric acid reached 7.279 mg/dl, and after the treatment, it decreased to 6.76 mg/dl. Conclusion: This study has established evidence that the boiled water of syzygium polyanthum leaves is able to decrease hyperuricemia (uric acid level in blood). Keywords: syzygium polyanthum, boiled water of syzygium polyanthum leaves, hyperuricemia

scholarly journals Development of a Topical Insulin Polymeric Nanoformulation for Skin Burn Regeneration: An Experimental Approach

2021 ◽  
Vol 22 (8) ◽  
pp. 4087
Author(s):  
Maria Quitério ◽  
Sandra Simões ◽  
Andreia Ascenso ◽  
Manuela Carvalheiro ◽  
Ana Paula Leandro ◽  
...  
Keyword(s):  
Wound Healing ◽  
Healing Process ◽  
In Vitro Release ◽  
Peptide Hormone ◽  
Plga Nanoparticles ◽  
Wound Healing Process ◽  
Target Area ◽  
Encapsulation Process

Insulin is a peptide hormone with many physiological functions, besides its use in diabetes treatment. An important role of insulin is related to the wound healing process—however, insulin itself is too sensitive to the external environment requiring the protective of a nanocarrier. Polymer-based nanoparticles can protect, deliver, and retain the protein in the target area. This study aims to produce and characterize a topical treatment for wound healing consisting of insulin-loaded poly-DL-lactide/glycolide (PLGA) nanoparticles. Insulin-loaded nanoparticles present a mean size of approximately 500 nm and neutral surface charge. Spherical shaped nanoparticles are observed by scanning electron microscopy and confirmed by atomic force microscopy. SDS-PAGE and circular dichroism analysis demonstrated that insulin preserved its integrity and secondary structure after the encapsulation process. In vitro release studies suggested a controlled release profile. Safety of the formulation was confirmed using cell lines, and cell viability was concentration and time-dependent. Preliminary safety in vivo assays also revealed promising results.

scholarly journals Kinetic analysis and optimisation of 18F-rhPSMA-7.3 PET imaging of prostate cancer

2021 ◽  
Author(s):  
Simona Malaspina ◽  
Vesa Oikonen ◽  
Anna Kuisma ◽  
Otto Ettala ◽  
Kalle Mattila ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Metastatic Disease ◽  
Uptake Kinetics ◽  
Whole Body ◽  
Target Area ◽  
Post Injection ◽  
The Mean ◽  
Pet Radiopharmaceutical ◽  
Time Frames ◽  
Over Time

Abstract Purpose This phase 1 open-label study evaluated the uptake kinetics of a novel theranostic PET radiopharmaceutical, 18F-rhPSMA-7.3, to optimise its use for imaging of prostate cancer. Methods Nine men, three with high-risk localised prostate cancer, three with treatment-naïve hormone-sensitive metastatic disease and three with castration-resistant metastatic disease, underwent dynamic 45-min PET scanning of a target area immediately post-injection of 300 MBq 18F-rhPSMA-7.3, followed by two whole-body PET/CT scans acquired from 60 and 90 min post-injection. Volumes of interest (VoIs) corresponding to prostate cancer lesions and reference tissues were recorded. Standardised uptake values (SUV) and lesion-to-reference ratios were calculated for 3 time frames: 35–45, 60–88 and 90–118 min. Net influx rates (Ki) were calculated using Patlak plots. Results Altogether, 44 lesions from the target area were identified. Optimal visual lesion detection started 60 min post-injection. The 18F-rhPSMA-7.3 signal from prostate cancer lesions increased over time, while reference tissue signals remained stable or decreased. The mean (SD) SUV (g/mL) at the 3 time frames were 8.4 (5.6), 10.1 (7) and 10.6 (7.5), respectively, for prostate lesions, 11.2 (4.3), 13 (4.8) and 14 (5.2) for lymph node metastases, and 4.6 (2.6), 5.7 (3.1) and 6.4 (3.5) for bone metastases. The mean (SD) lesion-to-reference ratio increases from the earliest to the 2 later time frames were 40% (10) and 59% (9), respectively, for the prostate, 65% (27) and 125% (47) for metastatic lymph nodes and 25% (19) and 32% (30) for bone lesions. Patlak plots from lesion VoIs signified almost irreversible uptake kinetics. Ki, SUV and lesion-to-reference ratio estimates showed good agreement. Conclusion 18F-rhPSMA-7.3 uptake in prostate cancer lesions was high. Lesion-to-background ratios increased over time, with optimal visual detection starting from 60 min post-injection. Thus, 18F-rhPSMA-7.3 emerges as a very promising PET radiopharmaceutical for diagnostic imaging of prostate cancer. Trial Registration NCT03995888 (24 June 2019).

scholarly journals 1-kHz high-frequency spinal cord stimulation alleviates chronic refractory pain after spinal cord injury: a case report

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Chiaki Yamada ◽  
Aiko Maeda ◽  
Katsuyuki Matsushita ◽  
Shoko Nakayama ◽  
Kazuhiro Shirozu ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Neuropathic Pain ◽  
Spinal Cord Stimulation ◽  
High Frequency ◽  
Cervical Vertebrae ◽  
Intractable Pain ◽  
Target Area ◽  
Positive Effects ◽  
Cord Injury

Abstract Background Patients with spinal cord injury (SCI) frequently complain of intractable pain that is resistant to conservative treatments. Here, we report the successful application of 1-kHz high-frequency spinal cord stimulation (SCS) in a patient with refractory neuropathic pain secondary to SCI. Case presentation A 69-year-old male diagnosed with SCI (C4 American Spinal Injury Association Impairment Scale A) presented with severe at-level bilateral upper extremity neuropathic pain. Temporary improvement in his symptoms with a nerve block implied peripheral component involvement. The patient received SCS, and though the tip of the leads could not reach the cervical vertebrae, a 1-kHz frequency stimulus relieved the intractable pain. Conclusions SCI-related symptoms may include peripheral components; SCS may have a considerable effect on intractable pain. Even when the SCS electrode lead cannot be positioned in the target area, 1-kHz high-frequency SCS may still produce positive effects.

scholarly journals Opportunities and Possibilities of Developing an Advanced Precision Spraying System for Tree Fruits

Sensors ◽  
2021 ◽  
Vol 21 (9) ◽  
pp. 3262
Author(s):  
Md Sultan Mahmud ◽  
Azlan Zahid ◽  
Long He ◽  
Phillip Martin
Keyword(s):  
Travel Speed ◽  
Crop Productivity ◽  
Target Area ◽  
Factors Affecting ◽  
Air Jet ◽  
Spraying Parameters ◽  
World Food Supply ◽  
Significant Damage ◽  
Tree Fruits ◽  
Precision Spraying

Reducing risk from pesticide applications has been gaining serious attention in the last few decades due to the significant damage to human health, environment, and ecosystems. Pesticide applications are an essential part of current agriculture, enhancing cultivated crop productivity and quality and preventing losses of up to 45% of the world food supply. However, inappropriate and excessive use of pesticides is a major rising concern. Precision spraying addresses these concerns by precisely and efficiently applying pesticides to the target area and substantially reducing pesticide usage while maintaining efficacy at preventing crop losses. This review provides a systematic summary of current technologies used for precision spraying in tree fruits and highlights their potential, briefly discusses factors affecting spraying parameters, and concludes with possible solutions to reduce excessive agrochemical uses. We conclude there is a critical need for appropriate sensing techniques that can accurately detect the target. In addition, air jet velocity, travel speed, wind speed and direction, droplet size, and canopy characteristics need to be considered for successful droplet deposition by the spraying system. Assessment of terrain is important when field elevation has significant variability. Control of airflow during spraying is another important parameter that needs to be considered. Incorporation of these variables in precision spraying systems will optimize spray decisions and help reduce excessive agrochemical applications.

scholarly journals Google Earth Engine Sentinel-3 OLCI Level-1 Dataset Deviates from the Original Data: Causes and Consequences

2021 ◽  
Vol 13 (6) ◽  
pp. 1098
Author(s):  
Egor Prikaziuk ◽  
Peiqi Yang ◽  
Christiaan van der Tol
Keyword(s):  
Meteorological Data ◽  
Original Data ◽  
Google Earth ◽  
Target Area ◽  
Pixel Resolution ◽  
Point Of Interest ◽  
Homogeneity Assumption ◽  
Google Earth Engine ◽  
Level 1 ◽  
Monitoring Service

In this study, we demonstrate that the Google Earth Engine (GEE) dataset of Sentinel-3 Ocean and Land Color Instrument (OLCI) level-1 deviates from the original Copernicus Open Access Data Hub Service (DHUS) data by 10–20 W m−2 sr−1μμm−1 per pixel per band. We compared GEE and DHUS single pixel time series for the period from April 2016 to September 2020 and identified two sources of this discrepancy: the ground pixel position and reprojection. The ground pixel position of OLCI product can be determined in two ways: from geo-coordinates (DHUS) or from tie-point coordinates (GEE). We recommend using geo-coordinates for pixel extraction from the original data. When the Sentinel Application Platform (SNAP) Pixel Extraction Tool is used, an additional distance check has to be conducted to exclude pixels that lay further than 212 m from the point of interest. Even geo-coordinates-based pixel extraction requires the homogeneity of the target area at a 700 m diameter (49 ha) footprint (double of the pixel resolution). The GEE OLCI dataset can be safely used if the homogeneity assumption holds at 2700 m diameter (9-by-9 OLCI pixels) or if the uncertainty in the radiance of 10% is not critical for the application. Further analysis showed that the scaling factors reported in the GEE dataset description must not be used. Finally, observation geometry and meteorological data are not present in the GEE OLCI dataset, but they are crucial for most applications. Therefore, we propose to calculate angles and extraterrestrial solar fluxes and to use an alternative data source—the Copernicus Atmosphere Monitoring Service (CAMS) dataset—for meteodata.

scholarly journals Combining regional to local restoration goals in the Brazilian Atlantic forest

2021 ◽  
Vol 21 (3) ◽  
Author(s):  
Cassia M.G. Lemos ◽  
Pedro R. Andrade ◽  
Ricardo R. Rodrigues ◽  
Leticia Hissa ◽  
Ana P. D. Aguiar
Keyword(s):  
Cost Effectiveness ◽  
Atlantic Forest ◽  
Natural Regeneration ◽  
Regional Level ◽  
Target Area ◽  
Brazilian Atlantic Forest ◽  
Regeneration Potential ◽  
Allocation Model ◽  
Alternative Scenarios ◽  
The Cost

AbstractTo achieve regional and international large-scale restoration goals with minimum costs, several restoration commitments rely on natural regeneration, a passive and inexpensive strategy. However, natural regeneration potential may vary within the landscape, mainly due to its historical context. In this work, we use spatially explicit restoration scenarios to explore how and where, within a given region, multiple restoration commitments could be combined to achieve cost-effectiveness outcomes. Our goal is to facilitate the elaboration of forest restoration plans at the regional level, taking into consideration the costs for active and passive restoration methods. The approach includes (1) a statistical analysis to estimate the natural regeneration potential for a given area based on alternative sets of biophysical, land cover, and/or socioeconomic factors and (2) the use of a land change allocation model to explore the cost-effectiveness of combining multiple restoration commitments in a given area through alternative scenarios. We test our approach in a strategic region in the Brazilian Atlantic Forest Biome, the Paraiba Valley in São Paulo State. Using the available data for 2011, calibrated for 2015, we build alternative scenarios for allocating natural regeneration until 2025. Our models indicate that the natural regeneration potential of the region is actually very low, and the cost-effectiveness outcomes are similar for all scenarios. We believe our approach can be used to support the regional-level decision-making about the implementation of multiple commitments aiming at the same target area. It can also be combined with other approaches for more refined analysis (e.g., optimization models).

scholarly journals High-Accuracy Recognition and Localization of Moving Targets in an Indoor Environment Using Binocular Stereo Vision

2021 ◽  
Vol 10 (4) ◽  
pp. 234
Author(s):  
Jing Ding ◽  
Zhigang Yan ◽  
Xuchen We
Keyword(s):  
Stereo Vision ◽  
Stereo Matching ◽  
Three Dimensional ◽  
Target Localization ◽  
Parallel Structure ◽  
Moving Target ◽  
Target Area ◽  
Moving Targets ◽  
Binocular Stereo Vision ◽  
Binocular Stereo

To obtain effective indoor moving target localization, a reliable and stable moving target localization method based on binocular stereo vision is proposed in this paper. A moving target recognition extraction algorithm, which integrates displacement pyramid Horn–Schunck (HS) optical flow, Delaunay triangulation and Otsu threshold segmentation, is presented to separate a moving target from a complex background, called the Otsu Delaunay HS (O-DHS) method. Additionally, a stereo matching algorithm based on deep matching and stereo vision is presented to obtain dense stereo matching points pairs, called stereo deep matching (S-DM). The stereo matching point pairs of the moving target were extracted with the moving target area and stereo deep matching point pairs, then the three dimensional coordinates of the points in the moving target area were reconstructed according to the principle of binocular vision’s parallel structure. Finally, the moving target was located by the centroid method. The experimental results showed that this method can better resist image noise and repeated texture, can effectively detect and separate moving targets, and can match stereo image points in repeated textured areas more accurately and stability. This method can effectively improve the effectiveness, accuracy and robustness of three-dimensional moving target coordinates.

scholarly journals Continuing Education in Health: interprofessional practices in the field of Collective Health

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
A P N Fornereto ◽  
M N Ogata ◽  
T A Santos ◽  
A B C Franceschini ◽  
MCRLR Pinto ◽  
...  
Keyword(s):  
Health Care ◽  
Primary Health Care ◽  
Continuing Education ◽  
Technical Assistance ◽  
Health Management ◽  
Multidisciplinary Teams ◽  
Target Area ◽  
Clinic Management ◽  
Primary Health ◽  
Health Support

Abstract Family Health Support Centres (NASFs, in Portuguese) aim to develop interprofessional practices anchored in the assumptions of Primary Health Care, guided by the criteria of shared care specific professional interventions, management processes, interdisciplinarity, intersectoriality, Continuing Education in Health and health promotion. This health management methodology (Matrix Support) still represents a challenge to workers and managers, as it switches the logic of clinical thought from individual-centred, ambulatory and disciplinary care to collective, territory and interdisciplinary care. This study might illustrate and allow sharing of experiences about a work management format for multidisciplinary teams in Primary Health Care. A partnership between the University and the state health department was established in order to elaborate a collaborative, educational and supportive action. We formed a group of workers in the target area (24 municipalities and 18 teams) who had a focus on Continuing Education in Health using Institutional Analysis as theoretical reference. The main goal of the action was to provide spaces to share experiences and learning in the perspective of Continuing Education in Health. How does Continuing Education in Health support interprofessional practices in the field of Collective Health? Among the main results, we list: reflection about organisation practices of multiprofessional work, reflection about care practices and clinic management in the technical-assistance and pedagogic perspectives of Matrix Support; encouragement to improve the services offered in this level of care and their relationship with other points of the network. This experience showed us the importance of three main aspects: Continuing Education in Health, as a strategy of critical analysis about work and workers; the partnership and integration between teaching and service; and interprofessional formation processes (necessary to NASF and Collective Health). Key messages Continuing Education in Health is a strategy to deal with challenges and possibilities of interprofessional practices in the field of Collective Health. Enabling experiences and providing spaces for health professionals to share experience and learning.

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