Effets histopathologiques de l'ingestion de plantes de milieux ouverts sur le foie de la souris de laboratoire

1983 ◽  
Vol 61 (9) ◽  
pp. 2147-2154
Author(s):  
Jean-Marie Bergeron ◽  
Louise Jodoin
Keyword(s):  
Body Weight ◽  
The Body ◽  
Histopathological Study ◽  
Juncus Effusus ◽  
Laboratory Mice ◽  
Secondary Products ◽  
Vacuole Formation ◽  
Mononucleated Cell ◽  
Commercial Feed

In previous studies, Bergeron and Goulet and Bergeron and Jodoin examined the effects of plant secondary products on the body weight and on the weight of different organs in laboratory mice; we made a histopathological study of the liver of the same animals. Within experimental groups kept on commercial feed and on shredded plants for 6 days, mice fed on ground ivy (Glecoma hederacea), strigose fleabane (Erigeron strigosus), lesser starwort (Stellaria graminea), hop-clover (Trifolium agrarium), and common rush (Juncus effusus) suffered centro- and peri-lobular necrosis. Apart from these extreme cases, other ailments were identified: hemorrhages, pycnosis, mononucleated cell infiltrations, congestion, and vacuole formation.[Translated by the Journal]

scholarly journals Nanoparticles for active combination radio mitigating agents of Zinc Coumarate and Zinc Caffeiate in a rat model

2021 ◽  
Author(s):  
Mostafa A. Askar ◽  
Mona S. Guida ◽  
Seham. M. AbuNour ◽  
Essam A. Ragab ◽  
Eiman N. Ali ◽  
...  
Keyword(s):  
Body Weight ◽  
Gamma Rays ◽  
Hematological Parameters ◽  
The Body ◽  
Histopathological Study ◽  
Biological Processes ◽  
T Helper ◽  
Γ Rays ◽  
Cd4 Cell ◽  
Morphological State

Abstract Zinc Coumarate and zinc caffeiatenano-particles (ZCoNPs, ZCaNPs) have been shown to affectthe different biological processes. This work was undertaken to evaluate the mitigating action of ZCoNPs in combination with ZCaNPsagainst liver damage induced by gamma rays (γ-rays). Rats were exposed to 7Gy of γ-rays, and theninjected intraperitoneally (i.p.) with ZCoNPs [2U / rat / day (5 mg/kg)], and ZCaNPs [2U / rat / day (15 mg/kg)] for 7 consecutive days.The results showed that irradiated rats treated with ZCoNPs (5 mg/kg/body weight) in combination with ZCaNPs (15 mg/kg/body weight) for 7 days revealed a significant increase in the body weight, antioxidants levels, T Helper (CD4) Cell and T Cytotoxic (CD8), associated with amarked decrease in the level of lipid peroxidation (LP), nitric oxide(NOx), total free radicals concentrate (TFRC), and DNA fragmentation. Moreover, positive alterations in the morphological state, hematological parameters, and thecell cycle phases were noticed. Additionally, the histopathological study demonstrated an improvement in the liver tissue of irradiated rats after treatment.Thus, ZCoNPs and ZCaNPscould be usedas a natural mitigating agent to reduce the hazards of ionizing radiation.

Pengaruh Penggunaan Limbah Feses Sapi Dan Probiotik Sebagai Bahan Pakan Pelet Terhadap Keuntungan Usaha Pemeliharaan Ikan Lele Dumbo

2017 ◽  
Vol 2 (4) ◽  
Author(s):  
Fahrina Fahrina ◽  
Yusdar Zakaria ◽  
M. Aman Yaman
Keyword(s):  
Body Weight ◽  
Analysis Of Variance ◽  
The Body ◽  
Feed Consumption ◽  
Total Income ◽  
Feed Ingredient ◽  
Feed Cost ◽  
Commercial Feed ◽  
Pellet Feed ◽  
Different Levels

Penelitian tentang pengaruh penggunaan limbah feses sapi dan probiotik sebagai bahan pakan pelet terhadap keuntungan usaha pemeliharaan ikan lele dumbo, telah dilakukan di Station Riset II (dua) Ie Suum, UPT. University Farm, Aceh Besar sejak tanggal 22 Mei – 14 Agustus 2016. Tujuan penelitian untuk melihat keuntungan usaha pemeliharaan ikan lele dumbo dengan menggunakan limbah feses sapi dan probiotik  sebagai bahan pakan pelet organik. Penelitian ini menggunakan 800 bibit ikan Lele Dumbo. penelitian berlansung 90 hari. Penelitian ini menggunakan Rancangan Acak Lengkap (RAL) terdiri dari 4 perlakuan dan 4 ulangan. Perlakuan yang dilakukan adalah penggunaan pakan pelet organik (PPO) dengan level yang berbeda yaitu P0=0%, P1=10%, P2=20%, P3=30% kedalam ransum komersil. Parameter yang diamati meliputi aspek produksi (berat badan akhir dan total konsumsi ransum) dan aspek ekonomis (penerimaan, biaya tetap, biaya variabel, Income over Feed Cost, dan total income). Data parameter produksi yang diperoleh dianalisis dengan Analysis of Variance (ANOVA), jika didapatkan perbedaan yang nyata, dilanjutkan dengan Uji Jarak Berganda Duncan (Steel dan Torrie, 1993). Data  parameter ekonomis dianalisis dengan B/C dan R/C ratio (Sjahrial, 2008). Hasil penelitian memperlihatkan bahwa penggunaan ransum komersil dengan pakan pelet organik pada level yang berbeda selama pemeliharan berpengaruh sangat nyata (P0.01) terhadap berat badan dan konsumsi ransum ikan lele dumbo. Penggunaan ransum komersil dengan pakan pelet organik selama pemeliharaan menurunkan biaya ransum dan menaikkan Income Over Feed Cost (IOFC)  dan total income pemeliharaan ikan Lele Dumbo. Pemberian pakan komersil 90% + PPO 10% layak dan menguntungkan dalam pemeliharaan ikan Lele Dumbo. Effect Of The Use Of  Waste Cow Feces And Probiotics As Pellet Feed Ingredient To The Profit Of Maintenance Business Of CatfishResearch on the effect of the use of cow feces waste and probiotics as pellet feed ingredient to the profit of maintenance business of catfish has been conducted in Research Station II (two) Ie Seum, UPT. University Farm, Aceh Besar from May 22, to August 14, 2016. The purpose of this research is to see the profit of  catfish maintenance business by using cow feces waste and probiotics as organic food pellet feed. This research uses 800 catfish seedlings , the studywas done for 90 days. This study used a complete randomized design (RAL) consisting of 4 treatments and 4 replications. Treatment was the used of organic feed pellets (PPO) with different levels as P0 = 0%, P1 = 10%, P2 = 20%, P3 = 30% into commercial ration. The parameters observed production of aspects (final body weight and total  feed consumption) and economic aspects  (revenue, cost, Income over Feed Cost, and total income). The former was analyzed by Analysis of Variance (ANOVA),  if significantly different results were detected, then continued by Duncan's Multiple Range Test (Steel and Torrie, 1993), while the latter was analysis by B/C and R/C ratio (Sjahrial, 2008).  The results of study showed that the use of commercial feed with an organic pellet feed at different levels during maintenance was highly significant (P 0.01) in the body weight and feed intake of catfish. The use of commercial feed with an organic pellet feed for lowering maintenance costs and increase the ration Income Over Feed Cost (IOFC), and total income maintenance catfish. Feeding commercial 90% + PPO 10% viable and profitable in the maintenance catfish.

scholarly journals Effects of growth promoter and multivitamin-mineral premix supplementation on body weight gain in broiler chickens

2013 ◽  
Vol 10 (2) ◽  
pp. 245-248 ◽  
Author(s):  
MA Rahman ◽  
MS Parvin ◽  
RR Sarker ◽  
MT Islam
Keyword(s):  
Body Weight ◽  
Weight Gain ◽  
Broiler Chickens ◽  
Body Weight Gain ◽  
The Body ◽  
Growth Promoter ◽  
Commercial Feed ◽  
Significant Difference ◽  
Group A ◽  
Group B

An experiment was conducted at the Khanpura Poultry Farm, near to the Babugonj campus of Patuakhali Science and Technology University, Patuakhali during the period from August to September, 2011 to evaluate the effect of growth promoter and multivitamin-mineral premix on the body weight gain in broiler chickens. A total of 90 ‘Cobb 500’ day-old broiler chickens were randomly divided into three equal groups (n = 30), namely Groups A, B and C. Broiler birds in groups A and B were supplemented with growth promoter and multivitamin-mineral premix, respectively in addition to commercial feed from day 4 till day 25. The dose of both the growth promoter and multivitamin-mineral premix was 2.5 g/kg of feed. Chickens of group C served as control and supplemented with commercial feed only. Body weight was recorded at three times as on day 11, 18 and 25, respectively. The mean body weight was insignificantly (p > 0.05) higher in birds of groups A (992.5±139.6g) and B (978.3±147.0g) than those of group C (926.7±133.2g). The percent increase in body weight gain compare to control was increased in both the supplemented groups (5.8% in group A and 8.8% in group B) though there was no significant difference. Based on the results, it is suggested that supplementation of growth promoter and multivitamin-mineral premix in broilers even after feeding of commercial feed has positive effect on the growth of broilers.DOI: http://dx.doi.org/10.3329/jbau.v10i2.14914 J. Bangladesh Agril. Univ. 10(2): 245-248, 2012

scholarly journals Toxicological characteristics of the preparation FORTICEPTTM Hoof Oinment

2018 ◽  
Vol 20 (92) ◽  
pp. 117-120
Author(s):  
V. D. Ishchenko ◽  
A. M. Shevchenko ◽  
N. M. Slobodyuk ◽  
R. O. Vasiv ◽  
H. V. Yarova ◽  
...  
Keyword(s):  
Body Weight ◽  
Acute Toxicity ◽  
The Body ◽  
Average Weight ◽  
Intragastric Administration ◽  
Laboratory Mice ◽  
White Rats ◽  
Medicinal Preparations ◽  
Medicinal Substances

Antibiotic resistance of the main infectious disease pathogens is one of the biggest problems of present time, which causes the need for searching for new antimicrobial medicinal substances and developing effective medicinal agents. One of the innovative medicinal preparations with the antimicrobial action, which is recommended for application for animals with hoof diseases, is ForticeptTM Hoof Oinment. Integration in the practice new medicinal preparations needs their strict toxicological control, which involves the exploring of acute and chronic toxicity and remote effects of possible side effect. The purpose of work was the determination of the acute toxicity parameters of the ForticeptTM Hoof Oinmentduring the oral administration to white laboratory mice and evaluation of the skin resorptive action of the preparation after it was administrated on rats’ skin. For determination of the acute toxicity there were used male laboratory mice with the average weight of the body 20 g – two groups with 10 animals in each. For the first group (the control one) with the help of the probe there was injected the distilled water (0.1 ml) into stomach. For the second group there was injected ForticeptTM Hoof Oinment (0.1 g), where the dose of the preparation is equal 500 mg/kg. For evaluation of the skin resorptive action of the preparation there were used 6 white rats with the average weight of the body 175 g. On the pre-prepared patch of skin there was administrated the preparation in the number that is equal 2857 mg/kg of body weight. For control there was leaved a free from preparation patch of bare skin. Exposition lasted for 4 hours. The indicators were explored in dynamics after 6, 24, 48 hours from the exposition started. After the research results there was established that ForticeptTM Hoof Oinment doesn’t cause death after its intragastric administration to the white laboratory mice in the number that is equal 5000 mg/kg of the body weight, that’s why depending on the degree of toxicity it belongs to the V toxicity class (Practically nontoxic). After one-time application of the preparation to the white rats in the number which is equal 2857 mg/kg of the body weight there wasn’t observes no death or pronounced changes in the behavior reactions, motor activity, state of the nervous system, amount of the consumed food and water. Therefore ForticeptTM Hoof Oinmentaccording to the results of the determination of the acute toxicity after its administration on the skin to the white rats depending on the degree of toxicity it belongs to the V toxicity class (Practically nontoxic). ForticeptTM Hoof Oinment doesn’t detect skin resorptive action, that points on the absence of toxic effects of the preparation due to its application on the skin.

scholarly journals Pengaruh Penambahan Sargassum sp. dan Inositol dalam Pakan terhadap Pertumbuhan dan Daya Tahan Juvenil Ikan Gurami (Osphronemus gouramy Lac.)

2017 ◽  
Vol 16 (2) ◽  
pp. 72
Author(s):  
Dwi Lestari ◽  
E. L. Widiastuti ◽  
N. Nurcahyani ◽  
G. N. Susanto
Keyword(s):  
Growth Rate ◽  
Body Weight ◽  
Survival Rate ◽  
Body Length ◽  
Growth Parameters ◽  
Freshwater Fishes ◽  
The Body ◽  
Body Width ◽  
Treatment Groups ◽  
Commercial Feed

Gourami (Osphronemus gouramy Lac.) as one of the freshwater fishes, are easily to be cultured but slow in growth rate. One of the ways to enhance their growth rate is by feeding them with high nutritious food. Sargassum sp. and inositol are known compound able to stimulate the growth of some fishes. The study was conducted to determine the effect of Sargassum sp and inositol on commercial feed to the growth rate and survival of juvenile gouramy. The study was conducted from January to April 2015 in Aquatic Laboratory of Biology Department - University of Lampung. Completely randomized designed was used with 4 treatment groups and 5 replications. Anova and Tukey at 5% levels were applied to this study. The result indicated that addition of inositol and Sargassum sp on commercial food significantly affected the gourami growth parameters such as the body weight, body length, body width as well as juvenile gouramy spesific growth rate and their survival rate.

Embelin modulates metabolic endotoxemia and associated obesity in high fat diet fed C57BL/6 mice

2020 ◽  
Vol 40 (1) ◽  
pp. 60-70
Author(s):  
P Bansal ◽  
U Bhandari ◽  
K Sharma ◽  
P Arya
Keyword(s):  
Body Weight ◽  
High Fat Diet ◽  
Serum Lipid ◽  
The Body ◽  
Histopathological Study ◽  
Histopathological Analysis ◽  
Lipid Levels ◽  
High Fat ◽  
Serum Lipid Levels ◽  
Metabolic Endotoxemia

The present study was designed to investigate the effect of embelin in metabolic endotoxemia (ME) mediated inflammation and associated obesity in high fat diet (HFD)-fed C57BL/6 mice. The molecular docking of embelin confirms its binding with the toll-like receptor-4 (TLR-4). In vivo study, mice were treated with HFD for 8 weeks to induce ME mediated inflammation and associated obesity. Further, mice were treated with embelin (50 and 100 mg/kg/day, p.o.) and orlistat (10 mg/kg/day, p.o.) from 5th to 8th week along with HFD to improve associated changes. After 8 weeks, mice were euthanized and assessed for body weight, body mass index (BMI), fat pad weights (mesenteric, retroperitoneal, and epididymal), intestinal permeability, TLR-4, tumor necrosis factor-α, interleukin-6, lipopolysaccharide, and serum lipid levels followed by histopathological analysis of liver and adipose tissues. Embelin significantly decreased the body weight, BMI, serum lipid levels, ME, and inflammation manifested by above parameters. Further, results of histopathological study showed that embelin restored the vacuolization, inflammation, one side shifting of nucleus in liver tissue, and decreased adipocyte cells size in adipose tissue in HFD-fed mice. Thus, our findings provide the strong evidence first time that embelin could modulate ME, mediate inflammation, and consequently reduce body weight gain, BMI, and serum lipid levels in HFD-fed mice.

scholarly journals Effects of commercial layer feed supplementation on haematological and reproductive parameters of indigenous duck in rural area

2016 ◽  
Vol 5 (1) ◽  
pp. 35-40 ◽  
Author(s):  
F Akter ◽  
MMR Howlader ◽  
MK Hossain ◽  
MMI Hasan ◽  
S Islam ◽  
...  
Keyword(s):  
Body Weight ◽  
Egg Production ◽  
Body Weight Gain ◽  
The Body ◽  
Total Leukocyte Count ◽  
Control Group ◽  
Feed Supplementation ◽  
Commercial Feed ◽  
Haematological Profile ◽  
Haemoglobin Content

This study was carried out to evaluate the effects of supplementation of commercial layer feed on body weight, egg production and haematological profile of the laying ducks rearing under the rural condition of Bangladesh. Twenty indigenous ducks (Khaki Campbell x Local duck) of 24 weeks old was selected from a farm and randomly divided into four equal groups (n=5) and numbered as group T0, T1, T2 & T3. The different amount of feed was supplied into four groups for three months. The all four groups (T0, T1, T2 and T3) were fed with routine feeding in scavenging condition. But T1 group supplemented with 120 gm, T2 group 60 gm and T3 group 30 gm of commercial feed. Significant differences were found in both egg production and haematological profile of ducks in compared to control group. Egg production was significantly (P<0.01) higher in T1 group compared to other groups. During the study the body weight gain were shown the same pattern being significantly (P<0.05) higher in T1 group compared to T0, T2 and T3 groups. On the other hand, the values of total erythrocyte count (TEC), total leukocyte count (TLC), haemoglobin content (Hb) and packed cell volume (PCV) increased significantly (P<0.05) in the groups of T1 and T2 compared to the control group (T0). But the value of MCV, MCH and MCHC of T1, T2 & T3 groups decreased significantly (P<0.05) than that of the control group. Results of the present study revealed that the amount of supplementation of commercial layer feeds was very important for improving the haematological profile and egg production of ducks. So, the additional commercial layer feed supplementation may be beneficial for duck farming.International Journal of Natural Sciences (2015), 5(1) 35-40

scholarly journals Effects of zeolite inclusion in aflatoxin B1-contaminated diet on the performance of laying duck

2019 ◽  
Vol 44 (3) ◽  
pp. 277
Author(s):  
I. Sumantri ◽  
H. Herliani ◽  
A. N. Rajibi ◽  
R. Edriantina
Keyword(s):  
Body Weight ◽  
Aflatoxin B1 ◽  
Egg Production ◽  
Liver Weight ◽  
The Body ◽  
Final Body Weight ◽  
Randomized Design ◽  
Commercial Feed ◽  
Feed Control

The researchwas objected to study the effect of zeolite inclusion in aflatoxin B1 (AFB1) contaminated diet on the performance of laying duck. A completely randomized design was adopted in the in vivo experiment that consisted of 4 treatments, namely: (1) commercial feed (Control); (2) AFB1-contaminated feed 70 ppb (AFC); (3) Control + 2% zeolite; and (4) AFC + 2% zeolite. Each treatment had 4 replications with 4 ducks in each replication. A total of 64 eight months-female Alabio duck (Anas platyrinchos Borneo) were used in 28 days of the feeding experiment. Data were analyzed according to the general linear model of SPSS 21.0 statistical software. Results indicated that AFB1 exposure significantly (P<0.05) decreased the body weight of laying duck by 1.12%. Zeolite inclusion could prevent the adverse effect of AFB1 on body weight that increased by 2.95% in AFC+2% zeolite. Treatments had no significant effect on egg production and egg weight (P>0.05). Zeolite inclusion resulted in the highest final body weight whilst AFB1 diet without zeolite resulted in the lowest final body weight (P<0.05). Relative liver weight of duck fedAFC diet was 16.62% and to be 15.4% by zeolite addition in the diet. In conclusion, 2% of zeolite inclusion could reduce the adverse effects of AFB1 exposure on the performance of laying duck.

scholarly journals Castration of Iraqi local bucks by bilateral spermatic cord torsion compared with double ligation of spermatic cord

2011 ◽  
Vol 10 (2) ◽  
pp. 21
Author(s):  
A. K. Munahi And Th. A.Abid
Keyword(s):  
Body Weight ◽  
Spermatic Cord ◽  
Serum Testosterone ◽  
Testicular Tissue ◽  
The Body ◽  
Control Group ◽  
Histopathological Study ◽  
Complete Suppression ◽  
Spermatic Cord Torsion ◽  
Black Goat

This study aimed to investigate the efficacy of using spermatic cord torsion as one of the easy castration techniques in Iraqi local black goat, and compared with double ligation of the spermatic cord also to be acquainted if the age of animals has an effect on spermatic cord torsion technique. This present study was done in the animals farm of the college of the veterinary medicine of Al-Qadissiya university, 30 local male blackbucks (15 kids of 2.5 - 3 months) (15 adult bucks of 13 - 15 months) with body weight (13.4 ± 2.21) and (31.9 ± 3.25) Kg respectively, were supplied for two symmetrical experiments, each one included division the animals randomly to three groups, first group (G1) left as control , Second group (G2) had spermatic cord ligation of both testes and third group (G3) had bilateral spermatic cord torsion and after two months orchiectomy of all tests were done to study the dimensions, the weight, histopathology of the testes and the level of serum testosterone hormone. The results revealed that the castration lead significance (P<0.01) to increase the body weight of both kids and bucks as compared with control, the maximum weight gained was in the bilateral spermatic cord torsion, while in the kids was the ligation group. Weights, lengths, and circumferences of both testes of all animals showed a significant decrease (P<0.01) as compared with control animals. Testosterone hormone analysis revealed a significant decrease (P<0.01) in its level in all castrated groups when compared with control group. Seminal analysis showed a significant decrease (P<0.01) (seminal plasma only) for the volume, concentration, viability, individual and mass motility of the sperms of the all castrated animals as compared with control. The histopathological study of all treated testes corroborated there were a severe degeneration and fibrosis in the testicular tissue as well as in the Sertoli and Leydig cells and complete suppression of spermatogenesis in all treated groups. The conclusion that spermatic cord torsion caused damage to the testes as ligation did with no effect of age of animals on this technique.

L-Ascorbic Acid Addition to Chitosan Reduces Body Weight in Overweight Women

2014 ◽  
Vol 84 (1-2) ◽  
pp. 5-11 ◽  
Author(s):  
Eun Y. Jung ◽  
Sung C. Jun ◽  
Un J. Chang ◽  
Hyung J. Suh
Keyword(s):  
Ascorbic Acid ◽  
Body Weight ◽  
Fat Body ◽  
Body Weight Gain ◽  
Skinfold Thickness ◽  
The Body ◽  
Control Group ◽  
Percentage Body Fat ◽  
Overweight Women ◽  
Body Weights

Previously, we have found that the addition of L-ascorbic acid to chitosan enhanced the reduction in body weight gain in guinea pigs fed a high-fat diet. We hypothesized that the addition of L-ascorbic acid to chitosan would accelerate the reduction of body weight in humans, similar to the animal model. Overweight subjects administered chitosan with or without L-ascorbic acid for 8 weeks, were assigned to three groups: Control group (N = 26, placebo, vehicle only), Chito group (N = 27, 3 g/day chitosan), and Chito-vita group (N = 27, 3 g/day chitosan plus 2 g/day L-ascorbic acid). The body weights and body mass index (BMI) of the Chito and Chito-vita groups decreased significantly (p < 0.05) compared to the Control group. The BMI of the Chito-vita group decreased significantly compared to the Chito group (Chito: -1.0 kg/m2 vs. Chito-vita: -1.6 kg/m2, p < 0.05). The results showed that the chitosan enhanced reduction of body weight and BMI was accentuated by the addition of L-ascorbic acid. The fat mass, percentage body fat, body circumference, and skinfold thickness in the Chito and Chito-vita groups decreased more than the Control group; however, these parameters were not significantly different between the three groups. Chitosan combined with L-ascorbic acid may be useful for controlling body weight.

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