scholarly journals Relationship between Toll-Like Receptor 8 Gene Polymorphisms and Pediatric Pulmonary Tuberculosis

2011 ◽  
Vol 31 (1) ◽  
pp. 33-38 ◽  
Author(s):  
Nazan Dalgic ◽  
Deniz Tekin ◽  
Zeliha Kayaalti ◽  
Erkan Cakir ◽  
Tulin Soylemezoglu ◽  
...  
Keyword(s):  
Pulmonary Tuberculosis ◽  
Strong Association ◽  
Research Priorities ◽  
Turkish Population ◽  
Host Susceptibility ◽  
Pulmonary Tb ◽  
Healthy Control ◽  
Pediatric Tuberculosis ◽  
Tuberculosis In Children ◽  
And Control

Objectives:Genetic variants in Toll-like receptors (TLRs) are considered a potential indicator for host susceptibility to and outcome of several infectious diseases including tuberculosis. The aim of this study was to determine whether −129 C/G and Met1Val polymorphisms of TLR8 were associated with pediatric pulmonary tuberculosis in Turkish population.Methods:The −129 C/G and Met1Val polymorphisms were studied in 124 children with pulmonary tuberculosis compared to 150 age-matched healthy control subjects.Results:We did not identify any statistically significant differences between the patients with TB and control groups with regard to the frequency of genotypes GG or G/(−), CG, and CC or C/(−); and alleles G and C at rs3764879 (p> 0.05). We found a strong association with genotype A/(−) at rs3764880 with susceptibility to pulmonary TB in males (OR 2.87, 95%CI 1.38–5.98,p= 0.007).Conclusions:Our results provide evidence, for the first time, of a role for the TLR8 gene in susceptibility to pulmonary TB in male children. Additional research to verify our results are necessary. Tuberculosis in children presents particularly difficult challenges, but research priorities and advances in pediatric tuberculosis could provide wider insights and opportunities for tuberculosis control.

scholarly journals Tuberculosis in Poland in 2017

2019 ◽  
pp. 211-226 ◽  
Author(s):  
Maria Korzeniewska- Koseła
Keyword(s):  
Pulmonary Tuberculosis ◽  
Incidence Rate ◽  
Prevention And Control ◽  
Incidence Rates ◽  
Age Group ◽  
Pulmonary Tb ◽  
Mdr Tb ◽  
Tuberculosis In Children ◽  
And Control ◽  
The Eu

AIM OF THE STUDY. To evaluate the main features of TB epidemiology in 2017 in Poland and to compare with the situation in the EU/EEA countries. METHODS. Analysis of case- based data on TB patients from National TB Register, data on anti-TB drug susceptibility testing results in cases notified in 2017, data from National Institute of Public Health- National Institute of Hygiene on cases of tuberculosis as AIDS-defining disease, data from Central Statistical Office on deaths from tuberculosis based on death certificates, data from ECDC report „European Centre for Disease Prevention and Control/WHO Regional Office for Europe. Tuberculosis surveillance and monitoring in Europe 2019-2017 data. Stockholm: European Centre for Disease Prevention and Control, 2019”. RESULTS. In 2017, 5 787 TB cases were reported in Poland. The incidence rate was 15.1 cases per 100 000, with large variability between voivodeships from 8.9 to 21.9 per 100 000. The mean annual decrease of TB incidence in 2013-2017 was 4.2%. In 2017, 5127 cases were newly diagnosed with no history of previous treatment i.e. 13.3 per 100 000. 660 cases i.e. 1.7 per 100 000 – 11.4% of all registered subjects were previously treated for tuberculosis. In 2017, the number of all pulmonary tuberculosis cases was 5 531 i.e. 14.4 per 100 000. Pulmonary cases represented 95.6% of all TB cases. In 2017, 256 extrapulmonary TB cases were found. In the whole country there were 68 pediatric cases of tuberculosis. TB in children represented 1.2% of all cases notified in Poland in 2017. The incidence rates of tuberculosis were growing along with the age group from 1.2 per 100 000 among children to 25.6 per 100 000 among subjects in the age group 45-64 years (the highest incidence rate). In 2017, the incidence rate in the age group ≥65 years was 22.6 per 100 000. The TB incidence among men i.e. 22.2 per 100.000 was 2.4 times higher than among women i.e. 8,4 per 100 000. The biggest difference in the TB incidence between the two sex groups occurred in persons aged 45 to 49 years – 36.1 vs. 8.1 and in age group 55- 59 years – 45.2 vs. 10.7. The TB incidence in rural population was lower than in urban, respectively 14.2 per 100.000 and 15.6 per 100 000. The number of all registered culture positive TB cases was 4 179. Pulmonary tuberculosis was bacteriologically confirmed in 4 057 subjects. Culture-confirmed cases represented 72.2% of all TB cases and 73.4% of all pulmonary TB cases. The number of smear-positive pulmonary TB cases reported in 2017 was 2 472 i.e. 6.4 per 100 000 accounting for 44.7% of all pulmonary TB cases and 60.9% of culture confirmed pulmonary TB cases.. TB was AIDS indicative disease in 16 subjects. In all patients with tuberculosis in Poland in 2017 there were 44 cases with MDR-TB (among them 12 foreigners) and 85 patients with resistance to isoniazid only, representing respectively 1.2% and 2.2% of cases with known DST results (DSTs were available in 90.5% of all cultureconfirmed TB cases). In 2017, there were 108 patients of foreign origin among all cases of tuberculosis in Poland. TUBERCULOSIS MORTALITY. There were 543 deaths due to tuberculosis reported in 2016 – 1.4 per 100 000; 526 people died from pulmonary and 17 from extrapulmonary tuberculosis. Mortality among males – 2.2 per 100 000 – was 3.7 X higher than among females – 0.6. 37.9% of all TB deaths were cases 65 years old and older – 3.3 per 100 000. In 2016, there was one death from tuberculosis in children and no deaths in adolescents. In 2016, tuberculosis represented 0.14% of total mortality in Poland and 28.1% of mortality from infectious diseases. CONCLUSIONS. In 2017, the incidence of tuberculosis in Poland was lower than in 2016. Despite a continuous decline it is still higher than the average in the EU/EEA countries. The highest incidence rates were observed in older age groups. The incidence in males was more than 2 times higher than in females. The impact of migration on the characteristics of tuberculosis in Poland is not substantial. In Poland, tuberculosis in children, tuberculosis in persons infected with HIV and MDR-TB is less common than the average in the EU/EEA countries.

scholarly journals KEPADATAN HUNIAN, VENTILASI DAN PENCAHAYAAN TERHADAP KEJADIAN TB PARU DI WILAYAH KERJA PUSKESMAS BINANGA KABUPATEN MAMUJU SULAWESI BARAT

2018 ◽  
Vol 3 (2) ◽  
pp. 75
Author(s):  
Dina Mariana ◽  
Miftah Chairani Hairuddin
Keyword(s):  
Pulmonary Tuberculosis ◽  
Home Environment ◽  
Case Control Study ◽  
Control Sample ◽  
Case Control ◽  
Residential Density ◽  
Pulmonary Tb ◽  
Potential Factors ◽  
And Control ◽  
Control Study

The home environment is one of the potential factors in the spread of Pulmonary Tuberculosis incidence. This study aims to analyze the environmental risk factors of the incidence of Pulmonary Tuberculosis in the working area Puskesmas Binanga Mamuju 2016. The study design is a case-control study. Sample size of 93 with a comparison between case and control 1: 2. TB case sample 31 patient and control sample 62 people. TB cases are pulmonary TB patients and controls, not the lungs. The data were collected by interview using questionnaire. Bivariate statistic test using Odds Ratio with α = 0,05. The results showed that residential density (OR 1.969, 95% CI: 0.641 - 6.049), Ventilation (OR 1.492, 95% CI: 0.576-3.863), and Lighting (OR 6.471, 95% CI: 0.795 - 52.6) significant to the incidence of pulmonary TB.

The Microbiome in Paediatric Crohn’s Disease—A Longitudinal, Prospective, 
Single-Centre Study

2019 ◽  
Vol 13 (8) ◽  
pp. 1044-1054 ◽  
Author(s):  
Shivani Kansal ◽  
Anthony G Catto-Smith ◽  
Karen Boniface ◽  
Sarah Thomas ◽  
Donald J Cameron ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Statistical Significance ◽  
Strong Association ◽  
Limited Information ◽  
Single Centre ◽  
Single Centre Study ◽  
Healthy Control ◽  
Gut Mucosa ◽  
And Control

AbstractBackground and AimsThe gut mucosa is the principal site where Crohn’s disease [CD] inflammation occurs. Limited information is available about the gut mucosal microbiome during CD relapse and remission. The aim of our study was to characterize specific changes in the gut microbiome during relapse and remission in a large single-centre paediatric CD cohort.MethodsWe analysed the microbiome of 345 biopsies from 204 patients, including 88 CD first diagnosis [CDFD] patients, 38 relapse [CDRL] patients, 12 remission [CDRM] patients, and 66 controls. Species identification was conducted using oligotyping in combination with ARB/SILVA taxonomic annotation.ResultsWe observed 45 bacteria to differ between CDFD samples and controls with statistical significance, with Fusobacterium being the most implicated species in CDFD patients. We also identified gender-specific differences in CD. Five species showed a strong association with CDRL patients and 10 species with CDRM patients. Three taxa showed a positive co-occurrence across the two groups. Hespellia porcina [closest taxonomic neighbour to Clostridium oroticum] was the most strongly associated with CDRL samples. Interestingly, Fusobacterium was not part of the CDRL-associated taxa group. Faecalibacterium prausnitzii was equally present in CDFD and control samples.ConclusionThis is the first study that has investigated the gut mucosal microbiome in a paediatric CD cohort with longitudinal sampling. Importantly, the microbiome of patients in CDRM did not return to a healthy control state. Neither did the microbiome of patients with CDRL return to the profile seen at CDFD.

scholarly journals Effect of Pursed Lip Breathing Exercise on Respiratory Frequency Among Tuberculosis Patients at Balai Besar Kesehatan Paru Masyarakat Makassar

2021 ◽  
pp. 545-552
Author(s):  
I Kade Wijaya ◽  
. Hasriany ◽  
Rioh Gunawan
Keyword(s):  
Pulmonary Tuberculosis ◽  
Intervention Group ◽  
Respiratory Frequency ◽  
Wilcoxon Test ◽  
Control Group ◽  
Breathing Frequency ◽  
Breathing Exercise ◽  
Tuberculosis Patients ◽  
Pulmonary Tb ◽  
And Control

Pulmonary tuberculosis patients tend to experience high respiratory frequency. The breathing muscles in patients who experience shortness of breath can work when respiratory abnormalities occur. This study aims to determine the effect of Pursed Lip Breathing Exercise on Respiratory Frequency among Pulmonary Tuberculosis Patients. The design in this study is a Quasi-Experimental design with a two-group approach, and a pre-test and post-test design. The sample is comprised of 20 patients in the Balai Besar Kesehatan Paru Masyarakat Makassar between 6 January – 8 February 2020. The instruments used in this study were the standard operational procedure of the Pursed Lip Breathing Exercise and the Respiratory Frequency Observation Sheet to determine the changes in the respiratory frequency of patients in the treatment and control groups. Statistics were analyzed using the T dependent test and Wilcoxon test. The Wilcoxon test result on the intervention group obtained the value of p = 0.004 or p < 0.05 and control group achieved p value = 0.157 or p > 0.05, it means the intervention group indicated influence and control group did not get any it. The intervention group that was treated by Pursed Lip Breathing Exercise acquired influence of breathing frequency on the pulmonary TB patients, but in another hand control group that only was measured the breathing frequency did not get any influence on the pulmonary TB patients.   Keywords: Tuberculosis, Breathing Frequency, Pursed Lip Breathing Exercise

scholarly journals ESTIMATE OF RISK FACTORS AND THE PHYSICAL ENVIRONMENT TO THE BEHAVIORS OF TUBERCULOSIS INCIDENCE IN THE WORKING AREA OF SIDRAP

2017 ◽  
Author(s):  
rahmi rahmi
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Pulmonary Tuberculosis ◽  
Rural Areas ◽  
Protective Factor ◽  
World Health ◽  
Observational Research ◽  
Pulmonary Tb ◽  
Humid Environment ◽  
And Control

The World Health Organization (WHO) in the Annual Report on Global TB Control states that there are 22 countries categorized as high burden countris against Pulmonary TB, including Indonesia. The prevalence of pulmonary tuberculosis in Indonesia ranks third after India and China that is almost 700 thousand cases, the death rate is still 275/100 thousand inhabitants. Characteristics of rural areas become a determinant of the incidence of pulmonary TB disease. The purpose of this study is how the estimation of physical environmental factors (home ventilation, humid environment, and occupancy density) is a risk factor for the incidence of TB Lung who live in the model stage house and How behavior factor estimation (Smoking, length of contact and stigma treatment) is a risk factor for the Lung TB incidence that resides in the stage model house.This research is an observational research with case control study approach. Where the population in this study were all positive pulmonary tuberculosis patients and suspected pulmonary tuberculosis in the work area of puskesmas Bilokka. While the sample in this study is divided into two, namely the case of 30 people and control samples as many as 60 people with a ratio between case and control 1: 2. Data collection through interviews that refer to the questionnaire and observation directly, Data analysis using bivariate statistical test with Odss Ratio through SPSS Version 19 program.Based on the results showed that the estimated risk factor proven as a risk factor for pulmonary TB incidence was the condition of ventilation (OR 13.02, 95% CI: 3.25-71.50). And non-risk factors were density (OR 1.36, 95% CI: 0.22-1.39), humid environment (OR 1.89, 95% CI: 0.19-1.27), smoking behavior (OR 1.57, 95% CI: 0.22-1,81), length of contact (OR 1.93, 95% CI: 0.38-2.61), and stigma behavior was a protective factor with (OR 0 , 32, 95% CI: 0.27-3.63).

scholarly journals GENETIC POLYMORPHISMS OF IL-17A IN ASSOCIATION WITH THE RISK OF PULMONARY TUBERCULOSIS IN IRAQI PATIENTS

2018 ◽  
Vol 11 (10) ◽  
pp. 428
Author(s):  
Nada Yas Ameen ◽  
Mohammed Qais Abed ◽  
Nawal Mohammed Utba ◽  
Ahmed Asmar Mankhi
Keyword(s):  
Infectious Disease ◽  
Mycobacterium Tuberculosis ◽  
Serum Level ◽  
Pulmonary Tuberculosis ◽  
Control Sample ◽  
Control Group ◽  
Case Group ◽  
Pulmonary Tb ◽  
Genotype Frequencies ◽  
Healthy Control

Objectives: Tuberculosis (TB) is an infectious disease that usually affects the lungs caused by Mycobacterium tuberculosis, TB is the second biggest killer, globally. The aim of this study was to examine the association between IL-17A rs2275913 SNP and pulmonary TB susceptibility in Iraqi population.Methods: From January 2017 to April 2017, 80 pulmonary TB patients were selected as the case group, another 40 healthy control were enrolled as the control group. The genotype frequencies of IL-17A rs2275913 was detected using amplification refractory mutation system.Results: The results of IL-17A serum level demonstrated that there were significant differences (p<0.05) between patients groups. The result showed that A allele have a higher frequency (55% vs. 50%) in TB patients than the control sample with OR value of 1.22 and EF value 0.1 and G have lower frequency (45% vs. 50%) in TB patients than control sample with OR value of 0.82 with PF value of 0.09, but this difference was not statistically significant (p>0.05).Conclusion: There were no significant associations between IL-17A rs2275913 polymorphism and risk of TB in Iraqi population.

scholarly journals Tuberculosis in Poland in 2018

2020 ◽  
pp. 239-257
Author(s):  
Maria Korzeniewska-Koseła
Keyword(s):  
Disease Prevention ◽  
Pulmonary Tuberculosis ◽  
Incidence Rate ◽  
Prevention And Control ◽  
Incidence Rates ◽  
Age Group ◽  
Pulmonary Tb ◽  
Mdr Tb ◽  
And Control ◽  
The Eu

AIM OF THE STUDY. To evaluate the main features of tuberculosis (TB) epidemiology in 2018 in Poland and to compare with the situation in the EU/EEA countries. METHODS. Analysis of case- based data on TB patients from National TB Register, data on anti-TB drug susceptibility testing results in cases notified in 2018, data from National Institute of Public Health- National Institute of Hygiene on HIV-positive subjects for whom TB was an AIDS-defining disease, data from Central Statistical Office on deaths from tuberculosis based on death certificates, data from the report „ European Centre for Disease Prevention and Control/WHO Regional Office for Europe. Tuberculosis surveillance and monitoring in Europe 2020- 2018 data. Stockholm: European Centre for Disease Prevention and Control, 2020”. RESULTS. In 2018, 5487 TB cases were reported in Poland. The incidence rate was 14.3 cases per 100000, with large variability between voivodeships from 7.3 to 23.4 per 100 000. The mean annual decrease of TB incidence in 2014- 2018 was 3.8%. In 2018, 4852 cases were newly diagnosed with no history of previous treatment i.e. 12.6 per 100 000. 635 cases i.e. 1.7 per 100 000 – 11.6% of all registered subjects were previously treated for tuberculosis. In 2018, the number of all pulmonary tuberculosis cases was 5224 i.e. 13.7 per 100000. Pulmonary cases represented 95.2% of all TB cases. In 2018, 243 extrapulmonary TB cases were found i.e. 0.6 per 100 000. In the whole country there were 52 pediatric cases of tuberculosis. TB in children represented 0.9% of all cases notified in Poland in 2018. The incidence rates of tuberculosis were growing along with the age group from 0.9 per 100 000 among children to 24.7 per 100 000 among subjects in the age group 45-64 years (the highest incidence rate). In 2018, the incidence rate in the age group ≥65 years was 21.3 per 100 000. The TB incidence among men i.e. 21.0 per 100 000 was 2.6 times higher than among women i.e. 8.0 per 100 000. The biggest difference in the TB incidence between the two sex groups occurred in persons aged 55 to 59 years – 44.9 vs. 9.8 and in age group 60- 64 years – 43.7 vs. 10.2. The TB incidence in rural population was lower than in urban, respectively 13.4 per 100 000 and 14.9 per 100 000. The number of all registered culture positive TB cases was 4075. Pulmonary tuberculosis was bacteriologically confirmed in 3935 subjects. Cases confirmed by culture represented 74.3% of all TB cases and 75.3% of all pulmonary TB cases. The number of smear-positive pulmonary TB cases reported in 2018 was 2324 i.e. 6.1 per 100 000 accounting for 44.3% of all pulmonary TB cases and 59.1% of pulmonary TB cases confirmed by culture. In all patients with tuberculosis in Poland in 2018 there were 48 cases with MDR-TB (among them 14 foreigners) and 83 patients with resistance to isoniazid only, representing respectively 1.3% and 2.2% of cases with known DST results (DSTs were available in 90.7% of all culture-confirmed TB cases). In 2018, there were 97 patients of foreign origin among all cases of tuberculosis in Poland. TB was AIDS-indicative disease in 14 subjects with HIV co-infection. There were 490 deaths due to tuberculosis reported in 2017 – 1.3 per 100 000; 468 people died from pulmonary and 22 from extrapulmonary tuberculosis. Mortality among males – 2.1 per 100 000 – was 3.6 X higher than among females – 0.5. 40.2% of all TB deaths were cases 65 years old and older – 3.1 per 100 000. In 2017, there was no death from tuberculosis in children and no deaths in adolescents. In 2017, tuberculosis represented 0.1% of total mortality in Poland and 25.4% of mortality from infectious and parasitic diseases. CONCLUSIONS. In 2018, the incidence of tuberculosis in Poland was lower than in 2017. Despite a continuous decline it is still higher than the average in the EU/EEA countries. The highest incidence rates were observed in older age groups. The participation of pediatric cases is smaller than average in the EU/EEA countries. The incidence in males was more than 2 times higher than in females. The impact of migration on the characteristics of tuberculosis in Poland is not substantial. In Poland, MDR-TB is less common than the average in the EU/EEA countries.

scholarly journals Hubungan antara pemberian imunisasi BCG, status gizi dan lingkungan rumah dengan kejadian penyakit TB paru pada anak balita

2020 ◽  
Vol 14 (3) ◽  
pp. 420-428
Author(s):  
Heny Noor Wijayanti ◽  
Didik Tamtomo ◽  
Nunuk Suryani
Keyword(s):  
Pulmonary Tuberculosis ◽  
Nutritional Status ◽  
Home Environment ◽  
Univariate Analysis ◽  
Case Control ◽  
Chi Square ◽  
Pulmonary Tb ◽  
Children Under Five ◽  
Under Five ◽  
Tuberculosis In Children

BCG vaccines, nutritional status, home environment and incidence of pulmonary tuberculosis among under five childrenBackground: Tuberculosis in children is an infectious disease in the respiratory tract that is difficult to detect, but its impact is sufficient to affect the child's development and health status of the child and even cause death. Therefore, it is necessary to take preventive measures by understanding the risk factors for the occurrence of tuberculosis in children, namely not receiving BCG vaccines, poor nutritional status and an unhealthy home environment.Purpose: To determine the relationship between BCG vaccines, nutritional status and home environment with the incidence of pulmonary TB disease in children under five at BKPM Semarang.Method: This study is an analytic observational study with a case control approach. The population of this study is all children under 5 years of age who are currently undergoing treatment at BKPM Semarang. The sample size in this study was 60 respondents consisting of two groups: 30 case groups and 30 control groups. Univariate analysis used percentage analysis, while bivariate analysis used Chi Square test (p = 0.05) and multivariate analysis used logistic regression.Results: There was no relationship between BCG vaccines and the incidence of pulmonary TB disease in children under five (p = 0.076; OR = 2.111). There is a relationship between nutritional status and the incidence of pulmonary tuberculosis in children under five (p = 0.000; OR = 2.750). Home environment: There is a relationship between occupancy density and the incidence of pulmonary TB disease in children under five (p = 0.000; OR = 7.538).Conclusion: Statistically, there is no significant between BCG vaccinesrelationship with the incidence of pulmonary TB disease in children under five. Several factors such as; Nutritional status and environmental conditions are closely related to the incidence of pulmonary TB.Keywords: Toddler; Pulmonary TB; BCG vaccines; Nutritional status; Home environmentPendahuluan: Tuberkulosis pada anak merupakan salah satu penyakit infeksi pada saluran pernafasan yang sulit terdeteksi, namun dampaknya cukup mempengaruhi perkembangan anak dan status kesehatan anak bahkan dapat menimbulkan kematian. Oleh karena itu, perlu dilakukan tindakan pencegahan dengan memahami faktor-faktor yang beresiko untuk terjadinya kejadian Tuberkulosis pada anak yaitu belum mendapatkan imunisasi BCG, status gizi yang kurang dan lingkungan rumah yang kurang sehat.Tujuan: Diketahui hubungan antara pemberian imunisasi BCG, status gizi dan lingkungan rumah dengan kejadian penyakit TB paru pada anak Balita di BKPM Semarang.Metode: Penelitian ini merupakan penelitian observasional analitik dengan pendekatan case control. Populasi penelitian ini yaitu seluruh anak yang usianya dibawah 5 tahun yang sedang melakukan pengobatan di BKPM Semarang. Besar sampel dalam penelitian ini adalah 60 responden yang terdiri dari dua kelompok: 30 kelompok kasus dan 30 kelompok kontrol. Analisis univariat digunakan analisis prosentase, sedangkan analisis bivariat digunakan uji Chi Square (p = 0,05) dan analisis multivariat digunakan regresi logistik. Hasil: Tidak ada hubungan antara pemberian imunisasi BCG dengan kejadian penyakit TB paru pada anak balita (p = 0,076; OR = 2,111). Ada hubungan antara status gizi dengan kejadian penyakit TB paru pada anak balita (p = 0,000; OR = 2,750). Lingkungan rumah: Ada hubungan antara kepadatan hunian dengan kejadian penyakit TB paru pada anak balita (p = 0,000; OR = 7,538).Simpulan: Secara statistik pemberian imunisasi BCG, tidak ada hubungan yang signifikan bermakna dengan kejadian penyakit TB paru pada anak balita. Beberapa faktor seperti; status gizi dan kondisi lingkungan rumah sangat berhubungan dengan kejadian penyakit TB paru 

Kualitas Hidup Pasien Tuberkulosis Paru yang Mengalami Stigma Diri (Quality of Life Pulmonary Tuberculosis Patients With Self Stigma))

2019 ◽  
Vol 3 (2) ◽  
pp. 17-27
Author(s):  
Yunita Sari
Keyword(s):  
Quality Of Life ◽  
Pulmonary Tuberculosis ◽  
Descriptive Study ◽  
Negative Influence ◽  
Questionnaire Data ◽  
Average Quality ◽  
Tuberculosis Patients ◽  
Pulmonary Tb ◽  
Life Score

Pulmonary tuberculosis (TB) is a chronic disease that can bring about the sufferer's self-stigma and also affect his quality of life. A number of studies report that living with TB has a negative influence on the quality of life of sufferers even with or without self-stigma. The purpose of this study was to identify the quality of life of TB patients who experienced self-stigma. This research is a descriptive study, sample were 31 pulmonary TB patients. Data was collected using a questionnaire. Data analyzed by using frequency distribution and percentage. The researcher first screened TB patients who experienced self-stigma. The results showed that 25 people (80.64%) respondents experienced mild self-stigma. A total of 9 respondents (36%) had a quality of life score in the good category and as many as 16 respondents (64%) had enough category with an average quality of life score is 56.57. While respondents who had moderate self-stigma were 6 people (19.36%) with a good quality of life score was 1 person (16.67%) and enough category quality of life score were 5 people (83.33%) with an average quality of life score is 49.92.

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