scholarly journals Semiconductor Quantum Dots (CdX, X = S, Te, Se) Modify Titanium Dioxide Nanoparticles for Photodynamic Inactivation of Leukemia HL60 Cancer Cells

2021 ◽  
Vol 2021 ◽  
pp. 1-24
Author(s):  
Qilin Pan ◽  
Miaomiao Li ◽  
Mucang Xiao ◽  
Yulu He ◽  
Guangyu Sun ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Titanium Dioxide ◽  
Visible Light ◽  
Separation Efficiency ◽  
Titanium Dioxide Nanoparticles ◽  
Semiconductor Quantum Dots ◽  
Photogenerated Carrier ◽  
Cdse Qds ◽  
Tio2 Nps ◽  
Targeting Ability

Titanium dioxide nanoparticles (TiO2-NPs) are highly efficient photosensitizers in traditional photodynamic therapy (PDT). The particle size of TiO2-NPs is small, only about 20 nm. However, the demands of ultraviolet light (UV) excitation feature shallow tissue penetration depth and may lead to severe tissue photon damage. Thus, in this research, TiO2-NPs are modified with semiconductor quantum dots (QDs) CdX (X = S, Te, Se) in various methods, such as ultrasonic, hydrothermal, sol-gel, aqueous phase, and hydrolysis precipitation. The transmission electron microscopy (TEM) images show that the size of CdSe-TiO2 is ranging from 6 to 14 nm. The ultraviolet-visible (UV-Vis) spectrum demonstrates that the CdX (X = S, Te, Se) modification can successfully extend the absorption range of TiO2-NPs into a different visible light region. CdSe QDs have the narrowest band gap compared with CdX (X = S, Te, Se) QDs. Visible light-activated CdSe-TiO2 nanocomposite shows the highest PDT inactivation efficiency toward HL60 cells compared with CdX-TiO2. The photogenerated carrier separation efficiency of CdSe-TiO2 nanocomposite is the highest shown in a fluorescence spectrum (FS). Furthermore, when conjugated with folic acid (FA), the prepared FA-CdX-TiO2 (X = S, Se) exhibits excellent cancer-targeting ability during PDT treatment. Optimum PDT efficiency of FA-CdSe-TiO2 indicates that photocatalytic and targeting ability is much higher than pure TiO2 and CdSe-TiO2. Our results provided a detailed investigation on the PDT performance of CdX (X = S, Te, Se) modified TiO2 and may act as a guide for further design of highly targeted performance visible-light response TiO2-NPs.

scholarly journals Salt Stress Mitigation via the Foliar Application of Chitosan-Functionalized Selenium and Anatase Titanium Dioxide Nanoparticles in Stevia (Stevia rebaudiana Bertoni)

Molecules ◽  
2021 ◽  
Vol 26 (13) ◽  
pp. 4090
Author(s):  
Morteza Sheikhalipour ◽  
Behrooz Esmaielpour ◽  
Gholamreza Gohari ◽  
Maryam Haghighi ◽  
Hessam Jafari ◽  
...  
Keyword(s):  
Titanium Dioxide ◽  
Salt Stress ◽  
Titanium Dioxide Nanoparticles ◽  
Chitosan Nanoparticles ◽  
Stevia Rebaudiana ◽  
High Salt ◽  
Steviol Glycosides ◽  
Rebaudioside A ◽  
Tio2 Nps ◽  
Stevia Rebaudiana Bertoni

High salt levels are one of the significant and major limiting factors on crop yield and productivity. Out of the available attempts made against high salt levels, engineered nanoparticles (NPs) have been widely employed and considered as effective strategies in this regard. Of these NPs, titanium dioxide nanoparticles (TiO2 NPs) and selenium functionalized using chitosan nanoparticles (Cs–Se NPs) were applied for a quite number of plants, but their potential roles for alleviating the adverse effects of salinity on stevia remains unclear. Stevia (Stevia rebaudiana Bertoni) is one of the reputed medicinal plants due to their diterpenoid steviol glycosides (stevioside and rebaudioside A). For this reason, the current study was designed to investigate the potential of TiO2 NPs (0, 100 and 200 mg L−1) and Cs–Se NPs (0, 10 and 20 mg L−1) to alleviate salt stress (0, 50 and 100 mM NaCl) in stevia. The findings of the study revealed that salinity decreased the growth and photosynthetic traits but resulted in substantial cell damage through increasing H2O2 and MDA content, as well as electrolyte leakage (EL). However, the application of TiO2 NPs (100 mg L−1) and Cs–Se NPs (20 mg L−1) increased the growth, photosynthetic performance and activity of antioxidant enzymes, and decreased the contents of H2O2, MDA and EL under the saline conditions. In addition to the enhanced growth and physiological performance of the plant, the essential oil content was also increased with the treatments of TiO2 (100 mg L−1) and Cs–Se NPs (20 mg L−1). In addition, the tested NPs treatments increased the concentration of stevioside (in the non-saline condition and under salinity stress) and rebaudioside A (under the salinity conditions) in stevia plants. Overall, the current findings suggest that especially 100 mg L−1 TiO2 NPs and 20 mg L−1 Cs–Se could be considered as promising agents in combating high levels of salinity in the case of stevia.

Impact of titanium dioxide nanoparticles on intestinal community in the 2,4,6-Trinitrobenzenesulfonic acid (TNBS)-induced acute colitis mice and the intervention effect of vitamin E

Nanoscale ◽  
2020 ◽  
Author(s):  
Yanjun Gao ◽  
Tingyu Li ◽  
Shuming Duan ◽  
Lizhi Lv ◽  
Yuan Li ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Titanium Dioxide ◽  
Vitamin E ◽  
Titanium Dioxide Nanoparticles ◽  
Trinitrobenzenesulfonic Acid ◽  
Acute Colitis ◽  
Intervention Effect ◽  
Tio2 Nps

Titanium dioxide nanoparticles (TiO2-NPs) is widely applicated as additives in foods for its excellent whitening and brightening capability. Although the toxicity and antibacterial activity of TiO2-NPs has been extensively studied,...

Effects the Surface of Solar-light Photocatalytic Activity of Ag-doped TiO2 Nanohybrid Material prepared with a Novel Approach

2021 ◽  
Author(s):  
G. Nagaraj ◽  
Mustafa K. A. Mohammed ◽  
Haider G. Abdulzahraa ◽  
S. Tamilarasu
Keyword(s):  
Visible Light ◽  
Degradation Rate ◽  
Titanium Dioxide Nanoparticles ◽  
Resonance Phenomenon ◽  
Bandgap Energy ◽  
Effective Strategy ◽  
Tio2 Nps ◽  
Photodegradation Efficiency ◽  
Novel Approach ◽  
Nanohybrid Material

Abstract Surface modification with a nanomaterial has been confirmed to be an effective strategy to enhance the visible-light photodegradation efficiency of titanium dioxide nanoparticles (TiO2-NPs). In this regard, we used silver as an additive into TiO2-NPs to improve their photodegradation activity under visible light irradiation. Herein, a novel and eco-friendly process was developed to prepare the Ag-doped TiO2 nanohybrid and named as photon-induced method (PIM). The XRD technique showed that the prepared Ag-doped TiO2 has mixed phases of anatase and rutile. However, the rutile-only phase was detected for the pure TiO2-NPs at 700°C of calcination. Ultraviolet-visible (UV-vis) absorption spectra revealed a reduction in the bandgap energy of TiO2 after Ag doping. Besides, the addition of Ag resulted in a significant improvement of TiO2 morphology. Methlyene blue (MB) dye was chosen to be an organic target to investigate the photocatalyst activity of the TiO2-NPs. In this regard, the degradation rate of MB was found to be 100% for the Ag-doped TiO2, which is higher than that of pure rutile TiO2. The incorporation of Ag additive plays a significant role in the improvement of TiO2 stability and photodegradation performance due to the surface plasmon resonance phenomenon.

scholarly journals Impact of Titanium Dioxide Nanoparticles on Cd Phytotoxicity and Bioaccumulation in Rice (Oryza sativa L.)

2020 ◽  
Vol 17 (9) ◽  
pp. 2979 ◽  
Author(s):  
Wei Zhang ◽  
Jinghua Long ◽  
Jianmin Geng ◽  
Jie Li ◽  
Zhongyi Wei
Keyword(s):  
Titanium Dioxide ◽  
Oryza Sativa ◽  
Plant Height ◽  
Oryza Sativa L ◽  
Titanium Dioxide Nanoparticles ◽  
Engineered Nanoparticles ◽  
Control Treatment ◽  
Booting Stage ◽  
Tio2 Nps ◽  
The Impact

The impact of engineered nanoparticles (ENPs) on the migration and toxicity of coexisting pollutants is still unclear, especially in soil media. This study aims to evaluate the impact of titanium dioxide nanoparticles (TiO2 NPs) on the phytotoxicity of cadmium (Cd) to Oryza sativa L., and the migration of cadmium (Cd) in the soil-rice system. Three different Cd stress groups (C1 group: 1.0 mg kg−1, C2 group: 2.5 mg kg−1 and C3 group: 5.0 mg kg−1) were set in the pot experiment, and the target concentration of TiO2 NPs in each group were 0 mg kg−1 (T0), 50 mg kg−1 (T1), 100 mg kg−1 (T2) and 500 mg kg−1 (T3). Plant height and biomass decreased with the increasing of Cd content in paddy soil. TiO2 NPs could lower the phytotoxicity of Cd in terms of the changes in the morphological and biochemical characteristics, especially in the tillering and booting stage. In the tillering stage, TiO2 NPs addition caused a significant increase in plant height, biomass and the total chlorophyll content in the leaves of Oryza saliva L. In the booting stage, TiO2 NPs addition caused a 15% to 32% and 24% to 48% reduction of malondialdehyde (MDA) content for the C2 and C3 group, respectively, compared to that of the respective control treatment (T0). TiO2-NPs addition reduced the activity of peroxidase (POD) in the leaves in the booting and heading stage, and the activity of catalase (CAT) in the tillering stage. In the C1 and C2 group, the grain Cd content in the 100 and 500 mg kg−1 TiO2 NPs treatments reached 0.47–0.84 mg kg−1, obviously higher than that of the treatment without TiO2 NPs (0.27–0.32 mg kg−1), suggesting that TiO2-NPs could promote Cd migration in the soil-rice system.

scholarly journals Internalization of Titanium Dioxide Nanoparticles Is Cytotoxic for H9c2 Rat Cardiomyoblasts

Molecules ◽  
2018 ◽  
Vol 23 (8) ◽  
pp. 1955 ◽  
Author(s):  
Elizabeth Huerta-García ◽  
Iván Zepeda-Quiroz ◽  
Helen Sánchez-Barrera ◽  
Zaira Colín-Val ◽  
Ernesto Alfaro-Moreno ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Cell Cycle ◽  
Cell Proliferation ◽  
Cell Death ◽  
Titanium Dioxide ◽  
Titanium Dioxide Nanoparticles ◽  
Membrane Integrity ◽  
The Body ◽  
Potential Health ◽  
Tio2 Nps

Titanium dioxide nanoparticles (TiO2 NPs) are widely used in industry and daily life. TiO2 NPs can penetrate into the body, translocate from the lungs into the circulation and come into contact with cardiac cells. In this work, we evaluated the toxicity of TiO2 NPs on H9c2 rat cardiomyoblasts. Internalization of TiO2 NPs and their effect on cell proliferation, viability, oxidative stress and cell death were assessed, as well as cell cycle alterations. Cellular uptake of TiO2 NPs reduced metabolic activity and cell proliferation and increased oxidative stress by 19-fold measured as H2DCFDA oxidation. TiO2 NPs disrupted the plasmatic membrane integrity and decreased the mitochondrial membrane potential. These cytotoxic effects were related with changes in the distribution of cell cycle phases resulting in necrotic death and autophagy. These findings suggest that TiO2 NPs exposure represents a potential health risk, particularly in the development of cardiovascular diseases via oxidative stress and cell death.

scholarly journals Titanium Dioxide Nanoparticles – Prospects and Applications in Medicine

2020 ◽  
Author(s):  
Daniel Ziental ◽  
Beata Czarczynska-Goslinska ◽  
Dariusz T. Mlynarczyk ◽  
Arleta Glowacka-Sobotta ◽  
Beata Stanisz ◽  
...  
Keyword(s):  
Titanium Dioxide ◽  
Metallic Nanoparticles ◽  
Malignant Tumors ◽  
Uv Light ◽  
Titanium Dioxide Nanoparticles ◽  
Aqueous Media ◽  
Resistant Bacteria ◽  
Antibiotic Resistant ◽  
Tio2 Nps ◽  
Wide Range

Metallic nanoparticles (NPs), among polymeric NPs, liposomes, micelles, quantum dots, dendrimers, or fullerenes, are becoming more and more important due to their potential use in the novel medical therapies. Titanium dioxide (titanium(IV) oxide, titania, TiO2) is an inorganic compound that owes its recent rise in scientific interest to photoactivity. After the illumination in aqueous media with UV light, TiO2 produces an array of reactive oxygen species (ROS). The capability to produce ROS and thus induce cell death has found application in the photodynamic therapy (PDT) for the treatment of a wide range of maladies, from psoriasis to cancer. Titanium dioxide NPs were studied as photosensitizing agents in the treatment of malignant tumors as well as in photodynamic inactivation of antibiotic-resistant bacteria. Both TiO2 NPs themselves, as well as their composites with other molecules, can be successfully used as photosensitizers in PDT. Moreover, various organic compounds can be grafted on TiO2 NPs, leading to hybrid materials. These nanostructures can reveal increased light absorption allowing their further use in targeted therapy in medicine. In order to improve efficient anticancer therapy, many approaches utilizing titanium dioxide were tested. The most significant studies are discussed in this review.

scholarly journals FOURIER TRANSFORM INFRARED SPECTROSCOPY CONTRIBUTION TO DISENTANGLE NANOMATERIAL (DWCNT, TIO2) IMPACTS ON TOMATO PLANTS

2021 ◽  
Author(s):  
Clarisse Liné ◽  
Juan Reyes-Herrera ◽  
Mansi Bakshi ◽  
Mohammad Wazne ◽  
Valentin Costa ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Titanium Dioxide ◽  
Fourier Transform ◽  
Infrared Spectroscopy ◽  
Fourier Transform Infrared Spectroscopy ◽  
Titanium Dioxide Nanoparticles ◽  
Fourier Transform Infrared ◽  
Terrestrial Ecosystems ◽  
Tomato Plants ◽  
Tio2 Nps

Carbon nanotubes (CNTs) and titanium dioxide nanoparticles (TiO2-NPs) are among the most used nanomaterials (NMs). However, their impacts especially on the terrestrial ecosystems and on plants are still controversial. Apart...

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