Abstract 13237: Impact of Pain and Heart Failure Symptom Severity on Physical Performance

Circulation ◽  
2014 ◽  
Vol 130 (suppl_2) ◽  
Author(s):  
Suzanne Wingate ◽  
Kushang V Patel ◽  
Jack Guralnik ◽  
Sarah Goodlin
Keyword(s):  
Heart Failure ◽  
Physical Performance ◽  
Symptom Severity ◽  
Kansas City ◽  
Brief Pain Inventory ◽  
Lower Extremity Function ◽  
Cross Sectional ◽  
Limited Mobility ◽  
Mobility Function ◽  
The Impact

Introduction: The purpose was to determine whether pain and heart failure (HF) symptom severity are associated with physical performance in patients with advanced HF. Methods: Cross-sectional data were analyzed on 160 adults with advanced HF (dyspnea or fatigue at rest or with minimal exertion despite optimal medical therapy). Demographics, comorbidity (Charlson), pain (Brief Pain Inventory), HF symptom severity (Kansas City Cardiomyopathy Questionnaire), and depression (Patient Health Questionnaire-9) data were obtained. Physical function was assessed with the Short Physical Performance Battery (SPPB), a measure of lower extremity function (timed walking speed, standing balance, chair rises). Scores range 0-12 (higher scores=better). Multivariable linear regression assessed the associations of pain and HF symptom severity with SPPB scores. Results: Subjects had a mean (standard deviation [SD]) age of 67.0 (15.9) years, 43% were women, and 19.6% were non-white. The mean (SD) SPPB score was 6.4 (3.6), indicating limited mobility function. Subjects in the highest quartile of pain (severe), as compared to those in the lowest quartile, had clinically significant decreased SPPB scores (b coefficient = -2.1; p<0.01), adjusting for demographics, comorbidity, and depression. However, this association was no longer significant when adjusting for HF symptom severity. For every SD increase in HF symptom severity, SPPB scores decreased 1.2 points (p<0.01). The combined effect of pain and HF symptom severity on SPPB scores (Table) suggests that pain exacerbates the impact of HF symptom severity on physical performance. Conclusions: Among patients with advanced HF, symptom severity was strongly associated with decreased physical performance. Pain may exacerbate HF symptom severity and contribute to decline in mobility function.

scholarly journals Composite Uremic Load and Physical Performance in Hemodialysis Patients: A Cross-Sectional Study

Toxins ◽  
2020 ◽  
Vol 12 (2) ◽  
pp. 135
Author(s):  
Karsten Vanden Wyngaert ◽  
Amaryllis H. Van Craenenbroeck ◽  
Els Holvoet ◽  
Patrick Calders ◽  
Wim Van Biesen ◽  
...  
Keyword(s):  
Muscle Strength ◽  
Exercise Capacity ◽  
Physical Performance ◽  
Ridge Regression ◽  
Handgrip Strength ◽  
Cross Sectional Study ◽  
Uremic Toxins ◽  
Sectional Study ◽  
Cross Sectional ◽  
The Impact

Impaired physical performance is common in patients on hemodialysis (HD) and is associated with poor prognosis. A patient relevant marker of adequacy of dialysis is lacking. Previous studies evaluated uremic toxicity by assessing the impact of different uremic toxins separately. However, such an approach is most likely not reflective of true uremic toxicity. Therefore, this cross-sectional study aimed to examine if the uremic syndrome, estimated as one composite of different uremic toxins (facilitated by ridge regression method) to reflect the kinetic behavior during dialysis, is associated with physical performance in patients on HD. Levels of p-cresyl glucuronide and sulfate, indole-acetic acid, indoxyl sulfate, uric acid, hippuric acid, and 3-carboxy-4-methyl-5-propyl-2-furanpropionic acid were assessed and associated by ridge regression to muscle strength, functional exercise capacity, and measures of balance and coordination. 75 HD patients were included (mean age 68 years, 57% male). The composite of different uremic toxins (i.e., uremic load) explained 22% of the variance in handgrip strength. Although there was an association between full body muscle strength and the composite uremic load independent of nutritional status, age and gender, the predictive power of composite uremic load for muscle weakness is limited. Single uremic toxins as well as composite uremic load were not associated with exercise capacity, coordination, and balance, indicating that the degree of uremia does not predict physical performance in patients on HD.

scholarly journals Social Support and Self- Care Behaviour among Heart Failure Patients

2019 ◽  
Vol 4 (12) ◽  
pp. 165
Author(s):  
Husna Ahmad Ainuddin ◽  
Siti Salwa Talib ◽  
Mohd Zhafran Zainal Abidin ◽  
Diana Katiman
Keyword(s):  
Heart Failure ◽  
Social Support ◽  
Clinical Training ◽  
Publishing House ◽  
Self Care ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Training Centre ◽  
Heart Failure Patients ◽  
The Impact

Heart failure is a disease that could cause a significant medical burden. This study aims to determine the relationship between social support and self-care behaviour among heart failure patients. Thirty patients from a Clinical Training Centre participated in this cross-sectional study. Instruments used in the study were the Multidimensional Scale of Perceived Social Support (MSPSS) and The European Heart Failure Self-care Behaviour Scale-9 item (EHFSCBC). The results showed that there was a relationship between social support and self-care behaviour (r=0.40, p<0.05). Awareness of the impact of social support on self-care behaviour is vital for heart failure patients and their families.Keywords: Heart failure, social support, self-care behavioureISSN: 2398-4287 © 2019. The Authors. Published for AMER ABRA cE-Bs by e-International Publishing House, Ltd., UK. This is an open-access article under the CC BYNC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia.DOI: https://doi.org/10.21834/e-bpj.v4i12.1906

scholarly journals Sports Participation, Demographic Factors and Knee Symptom Severity in Riyadh, Saudi Arabia

2021 ◽  
pp. 154-167
Author(s):  
Moaath A. Alamir ◽  
Abdulaziz F. Altammami ◽  
Faris H. Binyousef ◽  
Ahmed A. Alharbi ◽  
Feras A. Alrakaf
Keyword(s):  
Saudi Arabia ◽  
Symptom Severity ◽  
Online Survey ◽  
Sport Participation ◽  
Sports Participation ◽  
Exercise Duration ◽  
Severe Form ◽  
Cross Sectional ◽  
Lequesne Index ◽  
The Impact

Aims: to explore the prevalence of knee symptoms in the general population of Riyadh, Saudi Arabia, and evaluate the impact of sports participation and other demographic variables on the progression of knee symptoms in Riyadh, Saudi Arabia. Study design:  Cross-sectional study Place and duration of study: A self-administered online survey was conducted in Riyadh, Saudi Arabia between September 2020 to March 2021. Methodology: A total of 589 participants age 18 or older who reported concerns of knee symptoms and provided written informed consent were enrolled in the study. We excluded respondents who had undergone knee surgery (n = 16) and those diagnosed with rheumatoid arthritis or other types of arthritis (n = 25). We collected demographic information (eg, age, gender, types of engaged sports, sports participation hours, and frequency of participation per week) and knee symptoms and severity using the Lequesne index tool. Results: Advanced age was significantly associated with a higher severity score (P < .001). We found a statistically significant association between body mass index and knee symptom severity. We noted no severe knee symptoms in participants engaging in weightlifting. Most participants (64.7%) reported that walking was their most frequent exercise, and knee symptoms were common. Of respondents who walk as their primary sport, 10.6% of them are considered disabled with a severe form of knee pain according to the Lequesne index (which uses the term “handicapped” rather than disabled). Conclusion: Older and overweight respondents had a high prevalence of knee symptoms. Interestingly, the prevalence rates of individuals without knee symptoms did not differ regarding sport participation. Sports participation frequency did not change the prevalence or severity of knee symptoms, while longer exercise duration was associated with lower knee symptom severity rates.

scholarly journals Health Literacy but Not Frailty Predict Self-Care Behaviors in Patients with Heart Failure

2018 ◽  
Vol 15 (11) ◽  
pp. 2474 ◽  
Author(s):  
Youn-Jung Son ◽  
Dae Shim ◽  
Eun Seo ◽  
Eun Seo
Keyword(s):  
Heart Failure ◽  
Health Literacy ◽  
Chronic Diseases ◽  
Linear Regression Analysis ◽  
Self Care ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Educational Backgrounds ◽  
Key Factor ◽  
The Impact

Heart failure (HF) is a chronic condition requiring continuous self-care. Health literacy is increasingly recognized as a key factor of self-care behaviors in patients with chronic diseases. Recently, frailty in chronic diseases has also been associated with self-care behaviors. However, relationships among health literacy, frailty, and self-care in the HF population are not well understood. Therefore, this cross-sectional study aimed to identify the impact of health literacy and frailty on self-care behaviors in patients with HF. Data were collected from 281 adults attending a cardiovascular outpatient clinic in Korea. Health literacy, frailty, and self-care behaviors were measured using Korean-validated instruments. The mean scores of health literacy and self-care behaviors were 8.89 (±3.44) and 31.49 (±5.38), respectively. The prevalence of frailty was around 26.3%. Health literacy was significantly associated with frailty and self-care behaviors. In a hierarchical linear regression analysis, health literacy was a significant determinant of self-care behaviors after adjusting for confounding variables, but frailty was not. Educational level was also a significant predictor of self-care behaviors. Our main findings showed that health literacy can facilitate improvements in HF self-care behaviors. Healthcare professionals should assess patients’ health literacy and educational backgrounds when designing self-management programs.

scholarly journals COVID-19 prevalence and predictors in United States adults during peak stay-at-home orders

PLoS ONE ◽  
2021 ◽  
Vol 16 (1) ◽  
pp. e0245586
Author(s):  
Robert Morlock ◽  
Amy Morlock ◽  
Martha Downen ◽  
Sonali N. Shah
Keyword(s):  
Symptom Severity ◽  
Early Recognition ◽  
Nationwide Survey ◽  
Total Sample ◽  
International Travel ◽  
Community Based ◽  
Cross Sectional ◽  
The Us ◽  
The Impact ◽  
At Home

Background Early recognition of COVID-19 cases is essential for effective public health measures aimed at isolation of individuals infected with severe acute respiratory syndrome coronavirus 2 (SARS–COV-2). The objective of this study was to describe characteristics, self-reported symptoms, and predictors of testing positive for SARS-CoV-2 infection in a community-based sample. Methods and findings This was a cross-sectional nationwide survey of adults in the US conducted between April 24 through May 13, 2020. The survey targeted a representative sample of approximately 5,000 respondents. The rate of COVID-19 cases and testing, most frequently reported symptoms, symptom severity, treatment received, impact of COVID-19 on mental and physical health, and factors predictive of testing positive were assessed. Most of the 5,203 participants (85.6%) reported no COVID-19-like symptoms. Of the 747 (14.5%) participants reporting COVID-19-like symptoms, 367 (49.1%) obtained a diagnostic test. Eighty-nine participants (24.3%) reported a positive COVID-19 test result, representing 1.7% of the total sample. For those testing positive, the most common symptoms were dry cough, fever, and shortness of breath/difficulty breathing. Those who tested positive were more likely to report greater symptom severity versus those who tested negative. Severe dry cough, new loss of taste or smell, trouble waking up, living with someone experiencing symptoms, recent international travel, respiratory issues, and reporting ethnicity of Black or African American were predictive of testing positive. Conclusions This study assessed the impact of COVID-19 using community-level self-reported data across the US during the peak of most stay at home’ orders. Self-reported symptoms and risk factors identified in this study are consistent with the clinical profile emerging for COVID-19. In the absence of widespread testing, this study demonstrates the utility of a representative US community-based sample to provide direct-reported symptoms and outcomes to quickly identify high-risk individuals who are likely to test positive and should consider taking greater precautions.

scholarly journals Psychiatric morbidity and protracted symptoms in recovered COVID-19 patients

2020 ◽  
Author(s):  
Burç Çağrı Poyraz ◽  
Cana Aksoy Poyraz ◽  
Yeşim Olğun ◽  
Özge Gürel ◽  
Sena Alkan ◽  
...  
Keyword(s):  
Symptom Severity ◽  
Ptsd Symptom ◽  
Demographic Data ◽  
Acute Infection ◽  
Psychiatric Morbidity ◽  
Depression Scale ◽  
Binary Logistic Regression Analysis ◽  
Cross Sectional ◽  
Ptsd Symptom Severity ◽  
The Impact

AbstractWe investigated the psychiatric symptomatology and the protracted symptoms in recently recovered COVID-19 patients. This cross-sectional study assessed 284 patients recruited from a tertiary hospital. Patients completed a web-based survey on socio-demographic data, past medical/psychiatric history, and additional information relevant to the outbreak conditions. The psychiatric status was assessed using the Impact of Events Scale-Revised (IES-R), Hospital Anxiety and Depression Scale (HADS), Pittsburgh Sleep Quality Index (PSQI), and MINI suicidality scale. Patients completed a checklist for the acute symptom burden and protracted symptoms that were experienced after the acute infection. After a mean of 50 days following the diagnosis of COVID-19, 98 patients (34.5%) reported clinically significant PTSD, anxiety, and/or depression, with PTSD being the most common condition reported (25.4%). One hundred and eighteen patients (44.3%) reported one or more protracted symptom(s), with fatigue, muscle aches, alteration of smell/taste, headache and difficulty in concentration, being the most common symptoms reported. Predictors of PTSD symptom severity were the female gender, past traumatic events, protracted symptoms, perceived stigmatization, and a negative view on the seriousness of the COVID-19 pandemic. Binary logistic regression analysis showed that PTSD symptom severity was the sole independent predictor of the presence of protracted symptoms. Our results suggest that COVID-19 patients may be prone to substantial psychological distress in the first months after the infection. The protracted symptoms were also frequent in this period, and these were related to the posttraumatic psychiatric morbidity. Both the psychiatric morbidity and the protracted symptoms were independent of the initial infection severity. Further research on the neurobiological commonalities between the protracted symptoms and PTSD in COVID-19 patients is warranted.

Abstract 260: Coping and Health Related Quality of Life in Patients With Heart Failure: A Scoping Review

2020 ◽  
Vol 13 (Suppl_1) ◽  
Author(s):  
Mohammed O Alanazi ◽  
Gwen Wyatt ◽  
Ann Annis ◽  
Rebecca Lehto
Keyword(s):  
Quality Of Life ◽  
Heart Failure ◽  
Coping Strategies ◽  
Scoping Review ◽  
Health Related Quality ◽  
Cross Sectional ◽  
Related Quality ◽  
Health Related ◽  
The Impact

Purpose: Heart failure (HF) is associated with poor health-related quality of life (HRQoL) secondary to decrements in functional status. Patients’ adoption of coping strategies may affect their HRQoL. The review purpose was to characterize what is known about factors that impact selection of coping strategies that contribute to HRQoL among HF patients. Research Question/Hypothesis: What is known about: 1) the impact of coping strategies on HRQoL among patients with HF; and 2) factors affecting the adoption of coping strategies? Theoretical framework/rationale: This review was guided by Lazarus and Folkman’s stress and coping theory. Methods: A scoping review was conducted using the Arksey and O’Malley framework and a modified Preferred Reporting Items for Systematic Reviews and Meta-Analyses. Databases searched included PubMed, Web of Science, Cochrane, CINAHL, and PsycINFO. Keywords included: cope, coping, HF, congestive HF, HRQoL, coping strategies. Two investigators came to consensus on publications meeting eligibility criteria. Results: 674 articles were identified of which 471 articles were screened by title and abstract after duplicates were removed, with 27 meeting eligibility. 25 studies were quantitative and 2 qualitative. Six studies were randomized controlled trials, 18 were cross-sectional, and one was longitudinal. Participants’ ages ranged in age from 49-79. Most studies (n=18) reported a significant impact of coping strategies on HRQoL in HF patients, and six studies reported minimum to no impact. Factors that influenced the adoption of coping strategies were reported (n=7 studies): age, gender, religious belief, culture, depression and illness severity. Four of the seven studies reported depression as a significant factor in adopting coping strategies. Conclusion: Most studies found a significant impact on HRQoL through coping among HF patients. However, the majority of studies were cross-sectional in design, highlighting difficulties in determining causal relationships and changes over time. While only seven studies addressed factors that led to the use of coping strategies in HF, the leading contributors were sociodemographics along with depression. This review provides an overview of the state of science; lack of experimental studies suggests a gap in the literature and a need to explore this area of research.

scholarly journals High Inter-muscular Fat Is Associated with Poor Mobility Function in Older Adults, Only When Accompanied by Low Muscle Area (P01-026-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Samaneh Farsijani ◽  
Adam Santanasto ◽  
Peggy Cawthon ◽  
Robert Boudreau ◽  
Bret Goodpaster ◽  
...  
Keyword(s):  
Physical Performance ◽  
Univariate Analysis ◽  
Threshold Effect ◽  
Cross Sectional Area ◽  
Thigh Muscle ◽  
Sectional Area ◽  
Muscle Area ◽  
Cross Sectional ◽  
Mobility Function ◽  
Muscle Cross Sectional Area

Abstract Objectives To determine whether the associations between thigh inter-muscular-fat area, anthropometric characteristics and physical performance varies in old adults with low vs. high thigh muscle cross-sectional area. Methods Cross-sectional analysis of year 6 data from 1903 participants (52.2% women) of the Health ABC study aged 74–85y. Mid-thigh muscle composition (by CT), body composition (DXA) and physical performance were compared across quartiles of mid-thigh inter-muscular fat area. General linear model univariate analysis was used to study the associations between inter-muscular fat area and physical function according to low or high mid-thigh muscle cross-sectional area (using the 50th percentile). Results In participants with low mid-thigh muscle area, there was a threshold effect in which high inter-muscular fat was related to poor mobility function after the 2nd quartile (>23.7 cm2 in men and >21.3 cm2 in women). While, in participants with high mid-thigh muscle area, high inter-muscular fat was not associated with poor mobility function. Inter-muscular fat had no significant association with isokinetic knee strength in participants with either low or high muscle area. However, across all inter-muscular fat conditions, participants with low muscle area had lower leg strength than those with high muscle area. Conclusions The negative effects of inter-muscular fat in aging are greatly influenced by the presence of concurrent low muscle mass. Funding Sources NIA/NIH.

The Association of Physical-Performance Level with Attitude Toward Exercise in Older Adults

2003 ◽  
Vol 11 (2) ◽  
pp. 254-264 ◽  
Author(s):  
Milan Chang ◽  
Suzanne Leveille ◽  
Jiska Cohen-Mansfield ◽  
Jack M. Guralnik
Keyword(s):  
Older Adults ◽  
Physical Performance ◽  
Reference Group ◽  
Functional Limitations ◽  
Odds Ratios ◽  
Lower Extremity Function ◽  
Community Based ◽  
Cross Sectional ◽  
Positive Attitudes ◽  
Future Work

The Hebrew Home Study of Impairment and Exercise is a cross-sectional community-based study of nondisabled adults age 75–85 years that assessed attitude toward exercise by asking level of agreement with four statements evaluating participants’ perceptions of the health benefits and personal rewards of exercise. A physical-performance battery evaluated lower extremity function on a scale of 0 to 12. Attitude toward exercise was compared across 4 groups: non-vigorous exercisers with scores of 4–6 (n= 21), 7–9 (n= 90), or 10–12 (n= 113) and vigorous exercisers (n= 71). Vigorous exercisers had a significantly better attitude toward exercise than the reference group did, with odds ratios of 1.8-5.5 in all attitude statements. The lowest and moderate-performance groups had less positive attitudes toward exercise than the reference group did, with odds ratios of 0.27–0.62 for all statements. There was a highly significant gradient with better attitude toward exercise and higher functional-status level. Future work in improving older adults’ compliance with exercise should take into account the less positive attitude of those with functional limitations toward the benefits of exercise.

scholarly journals The role of physical and cognitive function in performance of activities of daily living in patients with mild-to-moderate Alzheimer’s disease – a cross-sectional study

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Frederikke K Clemmensen ◽  
Kristine Hoffmann ◽  
Volkert Siersma ◽  
Nanna Sobol ◽  
Nina Beyer ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Activities Of Daily Living ◽  
Physical Function ◽  
Physical Performance ◽  
Cognitive Functions ◽  
Daily Living ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
The Impact

Abstract Background Several factors may play a role in the ability of patients with Alzheimer’s disease to perform activities of daily living (ADL). The aim of this study was to examine the impact of different aspects of physical performance and cognitive functions on ADL in patients suffering from mild-to-moderate Alzheimer’s disease. Methods We conducted secondary analyses on cross-sectional baseline data from the randomized controlled multicentre study “Preserving quality of life, physical health and functional ability in Alzheimer’s Disease: The effect of physical exercise” (ADEX). In total, 185 AD patients (76 women and 109 men), with a mean age on 70,4 years, were included. Data from physical performance tests (Astrand cycle test, Timed up & Go (TUG), Sit to Stand test (STS)) and cognitive tests (Mini Mental Status Examination (MMSE), Symbol Digit Modalities Test (SDMT), Stroop Color and Word test (Stroop)) were used. Their associations with ADL, measured on the ADCS-ADL scale was assessed in multivariable regression analyses. Results SDMT and MMSE had significant, moderate correlations with total ADL (SDMT: r = 0.33, MMSE: r = 0.42) and instrumental ADL (SDMT: r = 0.31, MMSE: r = 0.42), but not with basic ADL. Adjusting for age and sex, the associations between SDMT and MMSE to total ADL and instrumental ADL persisted. No significant associations were found between Astrand, TUG, STS or Stroop and total ADL, basic ADL or instrumental ADL. Conclusion Total ADL and instrumental ADL are associated with cognitive functions, including executive function. No significant association between examined physical performance parameters and ADL functions was observed, and consequently does not support an impact of physical function on ADL functions in patients with mild-to-moderate Alzheimer’s disease and relatively well-preserved physical function. Strategies aimed to improve cognition may be better suited to improve ADL function in patients with mild-to-moderate Alzheimer’s disease. Trial registration NCT01681602. Registered 10 September 2012, retrospectively registered.

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