scholarly journals Occlusion and Temporomandibular Disorders: A Long-Standing Controversy in Dentistry

2020 ◽  
Vol 9 (1) ◽  
pp. 43-48
Author(s):  
Ziad Al-Ani
Keyword(s):  
Temporomandibular Disorders ◽  
Scientific Evidence ◽  
Contemporary Literature ◽  
Primary Factor ◽  
Specific Association ◽  
The Relationship ◽  
Disease Specific

The relationship between temporomandibular disorders (TMDs) and occlusion remains controversial. Some authors believe that occlusion is the primary factor in the onset of TMD symptoms, whereas others feel that occlusion has no role in this at all. The majority of reasoning behind causation is based upon anecdotal rather than scientific evidence. Existing evidence in the literature supports the absence of a disease-specific association. This article describes this controversy and provides the reader with findings from contemporary literature.

scholarly journals The knowledge level of dental surgeons regarding the relationship between occlusal factors and Temporomandibular Disorders (TMD)

2015 ◽  
Vol 44 (6) ◽  
pp. 360-367 ◽  
Author(s):  
Jefferson Filippo Castro de ASSIS ◽  
Pâmela Lopes Pedro da SILVA ◽  
Jully Anne Soares de LIMA ◽  
Franklin Delano Soares FORTE ◽  
André Ulisses Dantas BATISTA
Keyword(s):  
Temporomandibular Disorders ◽  
Software Package ◽  
Orofacial Pain ◽  
Scientific Evidence ◽  
Dental Occlusion ◽  
Knowledge Level ◽  
Chi Square ◽  
Standard Response ◽  
Spss Software ◽  
The Relationship

AbstractIntroductionThe relationship between dental occlusion and temporomandibular disorders (TMD) remains a subject of disagreement. Many professionals erroneously base diagnosis and treatment strictly on the occlusal factor, despite the fact that current scientific evidence does not show such a relationship.ObjectiveTo evaluate the knowledge of dental surgeons (DSs) from João Pessoa (PB)-Brazil, regarding the relationship between occlusal factors and TMD.Materials and methodA sample of 100 DSs who do not have expertise in TMD and orofacial pain (CG Group) and seven DSs with this specialty (EG Group) completed a questionnaire that addresses issues concerning knowledge of TMD and its relationship with occlusal factors. The questionnaire also contained information used to characterize the sample, such as age, gender, and length of experience. The current literature's degree of consensus was established as the "gold standard" response for each statement and was compared with the responses of the specialists and non-specialists. Data were tabulated using the SPSS software package and analyzed descriptively (by percentage) and statistically using the chi-square and Fisher's exact tests (p < 0.05).ResultA wide divergence could be observed between the knowledge of DSs who do not specialize in TMD and orofacial pain and that of professionals who do.ConclusionThere was low agreement between specialists and non-specialists. The relationship between dental occlusion and TMD remains unclear for the vast majority of participating professionals, which may prove to be reflected in diagnostic behaviors and inappropriate occlusal treatment for the management of TMD.

Influence of the Intestinal Microbiota on Diabetes Management

2020 ◽  
Vol 21 (15) ◽  
pp. 1603-1615
Author(s):  
Eva Alvarez-Vieites ◽  
Arora López-Santamarina ◽  
José M. Miranda ◽  
Alicia del Carmen Mondragón ◽  
Alexandre Lamas ◽  
...  
Keyword(s):  
Immune System ◽  
Intestinal Microbiota ◽  
Diabetes Management ◽  
Scientific Evidence ◽  
Focused Attention ◽  
Economic Implications ◽  
Experimental Animals ◽  
Low Intensity ◽  
New Treatments ◽  
The Relationship

In recent decades, there has been a very rapid increase in the prevalence of diabetes globally, with serious health and economic implications. Although today there are several therapeutic treatments for this disease, these do not address the causes of the disease and have serious side effects, so it is necessary to seek new treatments to replace or complement the existing ones. Among these complementary treatments, a strong link between the intestinal microbiota and diabetes has been demonstrated, which has focused attention on the use of biotherapy to regulate the function of the intestinal microbiota and, thus, treat diabetes. In this way, the main objective of this work is to provide a review of the latest scientific evidence on diabetes, gathering information about new trends in its management, and especially, the influence of the intestinal microbiota and microbiome on this pathology. It is possible to conclude that the relationship between the intestinal microbiota and diabetes is carried out through alterations in energy metabolism, the immune system, changes in intestinal permeability, and a state of low-intensity systemic inflammation. Although, currently, most of the experimental work, using probiotics for diabetes management, has been done on experimental animals, the results obtained are promising. Thus, the modification of the microbiota through biotherapy has shown to improve the symptoms and severity of diabetes through various mechanisms related to these alterations.

Explore the Possible Impact of BCG Vaccination Policy on the Morbidity, Mortality, and Recovery Rates due to COVID-19 Infection. (Preprint)

2020 ◽  
Author(s):  
Yue-Cune Chang
Keyword(s):  
Odds Ratio ◽  
Randomized Clinical Trials ◽  
Vaccination Policy ◽  
Bacille Calmette Guerin ◽  
Recovery Rates ◽  
Bcg Vaccination ◽  
The World ◽  
New Form ◽  
The Relationship ◽  
Disease Specific

BACKGROUND The Coronavirus Disease-19 (COVID-19) is the new form of an acute infectious respiratory disease and has quickly spread over most continents in the world. Recently, it has been shown that Bacille Calmette-Guerin (BCG) might protect against COVID-19. This study aims to investigate the possible correlation between BCG vaccination and morbidity/mortality/recovery rate associated with COVID-19 infection. OBJECTIVE Our findings confirm that the BCG vaccination might protect against COVID-19 virus infection. METHODS Data of COVID-19 confirmed cases, deaths, recoveries, and population were obtained from https://www.worldometers.info/coronavirus/ (Accessed on 12 June, 2020). To have meaningful comparisons among countries’ mortality and recovery rates, we only choose those countries with COVID-19 infected cases at least 200. The Poisson regression and logistic regression were used to explore the relationship between BCG vaccination and morbidity, mortality and recovery rates. RESULTS Among those 158 countries with at least 200 COVID-19 infected cases, there were 141 countries with BCG vaccination information available. The adjusted rates ratio of COVID-19 confirmed cases for Current BCG vaccination vs. non-Current BCG vaccination was 0.339 (with 95% CI= (0.338,0.340)). Moreover, the adjusted odds ratio (OR) of death and recovery after coronavirus infected for Current BCG vaccination vs. non-Current BCG vaccination were 0.258 (with 95% CI= (0.254,0.261)) and 2.151 (with 95% CI= (2.140,2.163)), respectively. CONCLUSIONS That data in this study show the BCG might provide the protection against COVID-19, with consequent less COVID-19 infection and deaths and more rapid recovery. BCG vaccine might bridge the gap before the disease-specific vaccine is developed, but this hypothesis needs to be further tested in rigorous randomized clinical trials. INTERNATIONAL REGISTERED REPORT RR2-https://doi.org/10.1101/2020.06.14.20131268

scholarly journals New Insights into Molecular Mechanism behind Anti-Cancer Activities of Lycopene

Molecules ◽  
2021 ◽  
Vol 26 (13) ◽  
pp. 3888
Author(s):  
Boon-Peng Puah ◽  
Juriyati Jalil ◽  
Ali Attiq ◽  
Yusof Kamisah
Keyword(s):  
Immune Cells ◽  
Scientific Evidence ◽  
Special Role ◽  
Real Potential ◽  
Wide Range ◽  
Anti Cancer ◽  
The Family ◽  
The Relationship ◽  
Cancer Activity ◽  
Reduced Risk

Lycopene is a well-known compound found commonly in tomatoes which brings wide range of health benefits against cardiovascular diseases and cancers. From an anti-cancer perspective, lycopene is often associated with reduced risk of prostate cancer and people often look for it as a dietary supplement which may help to prevent cancer. Previous scientific evidence exhibited that the anti-cancer activity of lycopene relies on its ability to suppress oncogene expressions and induce proapoptotic pathways. To further explore the real potential of lycopene in cancer prevention, this review discusses the new insights and perspectives on the anti-cancer activities of lycopene which could help to drive new direction for research. The relationship between inflammation and cancer is being highlighted, whereby lycopene suppresses cancer via resolution of inflammation are also discussed herein. The immune system was found to be a part of the anti-cancer system of lycopene as it modulates immune cells to suppress tumor growth and progression. Lycopene, which is under the family of carotenoids, was found to play special role in suppressing lung cancer.

scholarly journals Mechanics of the small punch test: a review and qualification of additive manufacturing materials

2021 ◽  
Vol 56 (18) ◽  
pp. 10707-10744
Author(s):  
Jonathan Torres ◽  
Ali P. Gordon
Keyword(s):  
Additive Manufacturing ◽  
Material Properties ◽  
Materials Science ◽  
Contemporary Literature ◽  
The Body ◽  
Small Punch Test ◽  
Small Punch ◽  
Punch Test ◽  
Testing Data ◽  
The Relationship

AbstractThe small punch test (SPT) was developed for situations where source material is scarce, costly or otherwise difficult to acquire, and has been used for assessing components with variable, location-dependent material properties. Although lacking standardization, the SPT has been employed to assess material properties and verified using traditional testing. Several methods exist for equating SPT results with traditional stress–strain data. There are, however, areas of weakness, such as fracture and fatigue approaches. This document outlines the history and methodologies of SPT, reviewing the body of contemporary literature and presenting relevant findings and formulations for correlating SPT results with conventional tests. Analysis of literature is extended to evaluating the suitability of the SPT for use with additively manufactured (AM) materials. The suitability of this approach is shown through a parametric study using an approximation of the SPT via FEA, varying material properties as would be seen with varying AM process parameters. Equations describing the relationship between SPT results and conventional testing data are presented. Correlation constants dictating these relationships are determined using an accumulation of data from the literature reviewed here, along with novel experimental data. This includes AM materials to assess the fit of these and provide context for a wider view of the methodology and its interest to materials science and additive manufacturing. A case is made for the continued development of the small punch test, identifying strengths and knowledge gaps, showing need for standardization of this simple yet highly versatile method for expediting studies of material properties and optimization.

scholarly journals How much is too much? (Part 1) International Olympic Committee consensus statement on load in sport and risk of injury

2016 ◽  
Vol 50 (17) ◽  
pp. 1030-1041 ◽  
Author(s):  
Torbjørn Soligard ◽  
Martin Schwellnus ◽  
Juan-Manuel Alonso ◽  
Roald Bahr ◽  
Ben Clarsen ◽  
...  
Keyword(s):  
Consensus Statement ◽  
Scientific Evidence ◽  
Research Priorities ◽  
Well Being ◽  
International Olympic Committee ◽  
Load Management ◽  
Risk Of Injury ◽  
Practical Guidelines ◽  
Relationship Of ◽  
The Relationship

Athletes participating in elite sports are exposed to high training loads and increasingly saturated competition calendars. Emerging evidence indicates that poor load management is a major risk factor for injury. The International Olympic Committee convened an expert group to review the scientific evidence for the relationship of load (defined broadly to include rapid changes in training and competition load, competition calendar congestion, psychological load and travel) and health outcomes in sport. We summarise the results linking load to risk of injury in athletes, and provide athletes, coaches and support staff with practical guidelines to manage load in sport. This consensus statement includes guidelines for (1) prescription of training and competition load, as well as for (2) monitoring of training, competition and psychological load, athlete well-being and injury. In the process, we identified research priorities.

scholarly journals Influence de la charge sur la production et la croissance de la vigne (c.v. Merlot)

OENO One ◽  
1987 ◽  
Vol 21 (2) ◽  
pp. 81
Author(s):  
M. Nikov
Keyword(s):  
Leaf Area ◽  
Shoot Growth ◽  
Inhibitory Effect ◽  
Yield Ratio ◽  
Primary Factor ◽  
First Year ◽  
Parabolic Curve ◽  
Grape Quality ◽  
Single Shoot ◽  
The Relationship

<p style="text-align: justify;">L'étude est menée avec le cépage Merlot conduit en forme haute et à une distance de 3,40 x 1,20 m. Les vignes supportent des charges individuelles de 26, 32, 38 ... jusqu'à 62 bourgeons par cep. La relation entre le nombre d'yeux et le rendement par souche se caractérise par une courbe parabolique avec un maximum autour de 50 bourgeons par cep. L'augmentation de charge au-delà de l'optimum exerce une influence inhibitrice sur la croissance des rameaux individuels depuis la première année. Le rapport entre la surface foliaire et la production représente un facteur essentiel pour la qualité du raisin.</p><p style="text-align: justify;">+++</p><p style="text-align: justify;">The study involves Merlot variety trained with an high trunk and a 3,40 x 1,20 m spacing. The vines support individual pruning levels of 26, 32, 38 ... up to 62 buds/vine. The relationship between bud number and yield per vine is characterized by a parabolic curve with a maximum around 50 buds/vine. The increase in pruning level beyond the optimum induces an inhibitory effect on single shoot growth since the first year. The leaf area : yield ratio represents a primary factor of grape quality.</p>

scholarly journals Impact of reverse globalization on the competition in EU digital markets

Industrija ◽  
2021 ◽  
Vol 49 (2) ◽  
pp. 7-24
Author(s):  
Snežana Radukić ◽  
Andrija Popović
Keyword(s):  
Competition Policy ◽  
Business Strategy ◽  
Contemporary Literature ◽  
Secondary Data ◽  
Relevant Information ◽  
Business Owners ◽  
Goods And Services ◽  
Number Of Individuals ◽  
The Relationship ◽  
The Eu

This paper aims to analyze the relationship between reverse globalization, the digital markets, and competition policy within the EU. Based on the review of contemporary literature, this paper provides an insight into the EU adaptation to the changes caused by the COVID-19 pandemic. Reverse globalization is identified through the trends in the international trade and FDI flows, while the digital markets' development is evaluated through the Number of individuals using the Internet to order goods and services and ECommerce sales. While this paper uses secondary data sources, it uniquely connects the identified reverse globalization and digital markets expansion with necessary changes in the competition policy pre and during the COVID19 pandemic. Additionally, this paper provides policymakers and business owners with relevant information and possible avenues to improve the competition policy and business strategy.

scholarly journals Ankyloglossia and breastfeeding: what is the evidence of association between them?

Revista CEFAC ◽  
2020 ◽  
Vol 22 (3) ◽  
Author(s):  
Mariana do Rêgo Barros de Andrade Fraga ◽  
Kamilla Azoubel Barreto ◽  
Thaís Christine Barbosa Lira ◽  
Pâmella Robertha Rosselinne Paixão Celerino ◽  
Izi Tuanny da Silva Tavares ◽  
...  
Keyword(s):  
Neonatal Screening ◽  
Scientific Evidence ◽  
Integrative Review ◽  
Future Research ◽  
Evaluation Instrument ◽  
Review Of The Literature ◽  
Early Weaning ◽  
Maternity Hospitals ◽  
The Relationship

ABSTRACT Purpose: to investigate the scientific evidence, in the literature, of the relationship between ankyloglossia and breastfeeding difficulties. Methods: an integrative review of the literature. The MEDLINE and PubMed databases were searched, using the following descriptors in combination: "ankyloglossia", "newborn" and "breastfeeding". The searches included articles published between 2014 and 2019, in Portuguese, English and Spanish. Original articles demonstrating an association between ankyloglossia and breastfeeding issues were selected. Results: a total of 31 articles was fully read in the analysis, 22 of which were excluded and 9 included in the review. There was a diversity of instruments used for the diagnosis of ankyloglossia. In four studies, no standardized evaluation instrument was used for the diagnosis of ankyloglossia, which may limit the analysis of the results. However, most studies have evidenced a possible influence of ankyloglossia on breastfeeding. According to the studies, babies with altered lingual frenulum were more likely to experience difficulties in sucking, showing early weaning, which shows the importance of neonatal screening as a routine protocol in maternity hospitals for the cases of ankyloglossia. Conclusions: ankyloglossia may be related to impaired breastfeeding. The standardization of instruments for the diagnosis of ankyloglossia is necessary to improve the evidence in future research.

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