scholarly journals Case–Control Research Study of Auto-Brewery Syndrome

2019 ◽  
Vol 8 ◽  
pp. 216495611983756 ◽  
Author(s):  
Barbara Jean Cordell ◽  
Anup Kanodia ◽  
Gregory K Miller
Keyword(s):  
Medical History ◽  
Case Control ◽  
Survey Study ◽  
Control Group ◽  
Asymptomatic Group ◽  
Health History ◽  
Bowel Movements ◽  
Control Research ◽  
Control Survey ◽  
Gut Fermentation

Background Auto-brewery syndrome (ABS), also known as Gut Fermentation Syndrome and Endogenous Ethanol Fermentation, is afflicting people worldwide, but little is known about ABS patients’ demographics, health history, lifestyle factors, and diet. Method We conducted a broad-based case–control survey study on 52 patients known to have a diagnosis of ABS and their household members. The research compares the symptomatic group (N = 28) to the asymptomatic group (N = 18) regarding lifestyle and health, diet, and medical history. Results With a response rate of 88% and using rank-sum tests, the data demonstrate that patients with ABS have significant differences compared to people without ABS in lower quality bowel movements ( P = .048), more frequent bowel movements ( P = .038), more reports of malodorous breath ( P = .0001), and self-classify as having poorer health ( P = .009). Furthermore, participants with ABS consume more water ( P = .038), consume less tea and coffee ( P = .033), eat fewer dairy products ( P = .0185), eat less candy ( P = .032), eat out less and rely on food prepared at home ( P = .043), have more aversion to starch ( P = .008), and have more food sensitivities ( P = .043) than the group without ABS. The ABS group also reports more diarrhea ( P = .048), higher amounts of yeast in their gastrointestinal tract ( P = .015), and using acne medication for a longer time ( P = .037) than the control group. Conclusion Patients with ABS have significant differences in their lifestyle and health, diet, and medical history compared to non-ABS participants and these differences warrant further research.

scholarly journals Factors in an Auto-Brewery Syndrome group compared to an American Gut Project group: a case-control study

F1000Research ◽  
2021 ◽  
Vol 10 ◽  
pp. 457
Author(s):  
Barbara Cordell ◽  
Anup Kanodia ◽  
Gregory K. Miller
Keyword(s):  
Case Control Study ◽  
Case Control ◽  
Food Allergies ◽  
Striking Difference ◽  
Control Group ◽  
General Group ◽  
Health History ◽  
Bowel Movements ◽  
Household Members ◽  
Control Study

Background: Auto-Brewery Syndrome (ABS), also known as Gut Fermentation Syndrome, is a rare but underdiagnosed condition. While scores of case studies of ABS are published, only one previous study examined ABS patients’ demographics, health history, lifestyle factors, and diet compared to a control group of household members. Methods: We designed a case-control study to identify factors that individuals with a diagnosis of ABS and those who live with them might have that differ from a larger general group. We administered a survey to 46 patients known to have a diagnosis of ABS and their household members. Here, we compare our group of survey takers to a cohort of the American Gut Project (AGP) participants (N=11,297) for the 30 questions that were identical. Results: With a response rate of 88% and using Rank Sum Tests, the data demonstrate that patients with ABS and their household members are more likely than participants of the AGP to own a pet (p=.03 for cat; p=.0001 for dog), get less sleep (p=.0001), and have lesser quality of bowel movements (p=.03). In addition, the ABS group consumes more water (p=.02) and less alcohol (p=.0004), eats at home more often (p=.0056), and reports more aversion to sweets (p=.01). The most striking difference is a higher presence of non-food allergies in all five subcategories of the survey in the ABS group compared to the AGP group. Conclusion: Patients with ABS and their household members show several significant differences in their lifestyle and health, diet, and medical history compared to a large group of AGP participants. These differences lead to several hypotheses about co-morbidities that warrant further research.

HUBUNGAN RIWAYAT SAKIT DENGAN KEJADIAN STUNTING PADA BALITA

2021 ◽  
Vol 3 (3) ◽  
pp. 213
Author(s):  
Hasanah Nurbawena ◽  
Martono Tri Utomo ◽  
Esti Yunitasari
Keyword(s):  
Case Control ◽  
Control Group ◽  
Case Group ◽  
Chi Square ◽  
Purposive Sampling ◽  
Group Data ◽  
Control Research ◽  
History Of ◽  
And Gender ◽  
Relationship Of

AbstrakLatar belakang : Kejadian stunting merupakan salah satu  masalah gizi pada anak yang memiliki prevalensi tinggi di Indonesia. Cut off point  kejadian stunting tidak boleh lebih dari 20%, sedangkan jumlah kejadian stunting di Surabaya sebanyak 22,8%. Salah satu penyebab tingginya kejadian stunting yaitu penyakit infeksi. Penelitian ini bertujuan untuk mengetahui hubungan riwayat sakit dengan kejadian stunting pada balita. Metode : Penelitian ini merupakan penelitian analitik observasional dengan menggunakan rancang penelitian case control. Jumlah sampel yang diteliti sebanyak 40 balita dengan usai 24-36 bulan di wilayah kerja Puskesmas Simomulyo Surabaya. Sampel penelitian balita stunting merupakan kelompok kasus dan balita non-stunting merupakan kelompok kontrol. Pengambilan data untuk kelompok kasus menggunakan purposive sampling dan pada kelompok kasus menggunakan matching sampling dengan menyesuaikan usia bayi dan jenis kelamin pada kelompok kasus. Pengumpulan data mengguanakan instrumen kuisioner. Uji statistik menggunakan chi square Hasil : Hasil penelitian ini didapatkan balita stunting memiliki riwayat sakit sebanyak 90%, sedangkan pada balita non-stunting sebanyak 45%. Uji statistik menggunakan mengenai hubungan riwayat sakit dengan kejadain stunting pada balita dengan uji Chi square didapatkan hasil yang signifikan yaitu p=0,002 (<0,05) dan OR 4,889. Kesimpulan : Balita stunting memiliki riwayat sakit lebih sering daripada balita non-stunting.AbstractBackground: . The incidence of stunting is one of the nutritional problems in children who have a high prevalence in Indonesia. The cut off point for stunting events should not be more than 20%, while the number of stunting events in Surabaya is 22.8%. One of the causes of the high incidence of stunting is an infectious disease. This study aimed to determine the relationship of a history of illnes with the incidence of stunting in infants. Method: This research was an observational analytic study using a case control research design. The number of samples were 40 toddlers (20 toodlers with stunting and 20 toodlers with non-stunting) aged 24-36 months in the working area of the Simomulyo Primary Health Care in Surabaya. The stunting toddlers belonged to a case group and non-stunting toddlers belonged to a control group. Data collection of case group had used purposive sampling and that control group used matching sampling by adjusting the baby's age and gender in the case group. Data was obtained by questionnaire instrument.Data was analysis by Chi square Results: The persentage of stunting toddlers who had a history of illness was 90%, while the non-stunting toddlers had a history of illness was 45%. There was relationship between the history of infectious diseases and the occurrence of stunting in toodler p=0,022 (<0,05) and OR=4,338. Conclusion: Stunting toddlers have a history of pain more often than non-stunting toddlers 

scholarly journals Outcomes of mentored, grant-funded fellowship training in haemostasis /thrombosis: findings from a nested case-control survey study

Haemophilia ◽  
2011 ◽  
Vol 18 (3) ◽  
pp. 326-331 ◽  
Author(s):  
N. A. GOLDENBERG ◽  
R. KRUSE-JARRES ◽  
N. FRICK ◽  
S. W. PIPE ◽  
C. A. LEISSINGER ◽  
...  
Keyword(s):  
Fellowship Training ◽  
Case Control ◽  
Survey Study ◽  
Control Survey ◽  
Nested Case Control

scholarly journals Factors of Incidence of Hypertension in Southwest Sumba

2020 ◽  
Vol 2 (2) ◽  
pp. 86-96
Author(s):  
Apliana Lupu Kaka ◽  
Johny A.R Salmun ◽  
Agus Setyo Budi
Keyword(s):  
Blood Pressure ◽  
Case Control ◽  
Smoking Habits ◽  
Observational Research ◽  
Control Group ◽  
Case Group ◽  
A Value ◽  
Control Research ◽  
And Control ◽  
The Relationship

Hypertension in conditions when blood pressure is at a value of 130/80 mmHg or more with the number of cases experiencing an increase from 2016-2018, Tana Mete Village, Kodi Balaghar District. in 2016 there were 880 (8.8%), cases in 2017 were 2,580 (25.8%) cases and in 2018 there were 3. 410 (34.1%) cases. Hypertension in influenced by factors of age, smoking habits, stress, and alcohol consumption. This study aims to analyze the relationship between age, smoking habits, stress, and alcohol comsuption. This research is an analytic observational research with a case control research design. The number of cases in Tana Mete Village, Kodi Balaghar District, Southwest Sumba Regency was 220 (22%) and the sample was 80 respondents and divided into two groups, namely the case and control group, the case group was 40 respondents and the control group was 40 respondents. These variables have been analyzed univariately and bivariately, the results of this study incidate that there are three risk factor variables for the incidence of hypertentsion. Namely age with a value p= 0.003, OR=4.059 (95% CI: 1.568-10.510), smoking habits with a value p=0.001, OR: 6.378 (95%CI:2.280-17.842), stress with a value of p=0.014, OR: 3.095 (95%CI: 3.095-7.706) while the variable alcohol comsumption has no relationship with the value of p=0.133. To prevent the occurrence of hypertension, the activities undertaken include avoiding smoking, stress and taking time for recreation.

scholarly journals SNP G-1082A IL-10 GENE: ALLELE AND GENOTYPE DISTRIBUTION OF PERIODONTITIS PATIENT IN YOGYAKARTA

2016 ◽  
Vol 19 (2) ◽  
pp. 117-120
Author(s):  
Rezmelia Sari ◽  
Prayitno Prayitno ◽  
Alya Nur Fadhilah
Keyword(s):  
Gene Polymorphism ◽  
Case Control ◽  
Control Group ◽  
Case Group ◽  
Genotype Distribution ◽  
Inclusion Criteria ◽  
Cotton Swab ◽  
Periodontitis Patient ◽  
Pcr Rflp ◽  
Control Research

Periodontitis is multifactorial inflamation process and related to disproportion of cytokine. IL-10 is a dominant noninflammatory cytokines that related to gene polymorphism. Polymorphism G-1082A IL-10 genes has been reported to increase the risk of periodontitis occurs in Italian populations, apart from different result found in Brazilian. The purpose of this research was to determine the polymorphism G-1082A IL-10 in periodontitis patients in Indonesia, especially among Yogyakarta’s Javanese. This is a case-control research with subjects according to the inclusion criteria. DNA was taken by cotton swab from the epithelial cells of buccal mucosa, and was isolated using a PrestoTM (GeneAid) kit. Genotyping analysis by using the PCR RFLP technique and descriptive results were presented. The result showed that A allele frequency is 100% and no G allele was found. AA genotype in case group has lower frequency than in control group and vice versa. From this research, it was concluded that A allele was dominant in Yogyakarta’s Javanese, and AA genotype frequency is lower in individual with periodontitis.

scholarly journals Correlation Between Craniovertebral Angle and Thickness of Longus Colli in Women with and Without Forward Head Posture

2021 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Fatemeh Bokaee ◽  
Ehsan Ghasemi ◽  
Fateme Etemadi ◽  
Sedighe Sadat Naimi
Keyword(s):  
Case Control ◽  
Control Group ◽  
Control Groups ◽  
Forward Head Posture ◽  
Head Posture ◽  
Longus Colli ◽  
Control Research ◽  
Craniovertebral Angle ◽  
And Control ◽  
The Relationship

Background: Forward head posture (FHP) of the craniocervical region is one of the most common poor postures. The craniovertebral angle (CVA) is one of the most common methods to evaluate this posture. The longus colli (LCo) muscle is an important muscle to control head posture. Objectives: This study aimed to evaluate the relationship between CVA and thickness of LCo in women with FHP. Methods: This case-control research included 35 women with FHP and a control group. Sagittal view photography of the cervical spine was used for measurement of CVA. An ultrasonography device measured the thickness of the LCo. Correlation between CVA and thickness of LCo was determined using correlation coefficient in both groups. Results: Our findings showed a non-significant correlation between the CVA and thickness of LCo in case and control groups. Conclusions: According to the results of this study, there was no significant correlation between a lower CVA and smaller thickness of LCo.

scholarly journals HUBUNGAN KEBERADAAN BREEDING PLACE DENGA DAN RESTING PLACE DENGAN KEJADIAN DBD DI KELURAHAN KALOSI KECAMATAN ALLA

2020 ◽  
Vol 3 (1) ◽  
pp. 9
Author(s):  
Rahmi Amir ◽  
Sona Sona
Keyword(s):  
Dengue Fever ◽  
Case Control ◽  
Control Group ◽  
P Value ◽  
Case Group ◽  
Control Instrument ◽  
Control Research ◽  
Relationship Of ◽  
The Village ◽  
Breeding Place

Abstrak            Keberadaan breeding place dan resting place nyamuk merupakan faktor yang mendukung untuk meningkatnya vektor penular DBD karena apabila semakin banyak breeding place menampung air yang berada di sekitar dan dalam rumah maka menjadi kesempatan untuk nyamuk bertelur dan berkembangbiak sehingga meningkatkan risiko kejadian DBD.Penyakit Demam Berdarah Dengue (DBD) merupakan salah satu masalah kesehatan masyarakat di Indonesia yang cenderung meningkat jumlah penderita serta semakin luas penyebarannya.Penelitian ini bertujuan untuk mengetahui hubungan breeding place dan resting place dengan kejadian DBD di Kelurahan Kalosi Kecamatan Alla.Jenis penelitian yang dilakukan adalah analitik observasional dengan desain penelitian case control yang diarahkan untuk menjelaskan suatu keadaan atau situasi yang dilakukan dengan cara membandingkan antara kelompok kasus dengan kelompok control. Instrument yang digunakan dalam penelitian ini menggunakan kuesioner dengan jumlah sampel kasus 15 kontrol 15 responden.Hasil penelitian menunjukkan  tidak ada hubungan bermakna antara keberadaan breeding place dengan kejadian demam berdarah dengue di Kelurahan Kalosi Kecamatan Alla dengan p value .000 sebesar (OR=21.79 CI= 8.38-56.66)ada hubungan bermakna antara keberadaan resting place dengan kejadian demam berdarah dengue di Kelurahan Kalosi Kecamatan Alla dengan p value sebesar .000 (OR=11.56, CI= 5.08-26.31) Diharapkan bagi masyarakat agar ikut serta berpartisipasi dalam upaya Pemberantasan Sarang Nyamuk Demam Berdarah Dengue (PSN-DBD). Kepada petugas Puskesmas melakukan pemeriksaan jentik secara rutin 3 bulan sekali, pelaksanaan fogging dan meningkatkan promosi kesehatan kepada masyarakat tentang cara mencegah DBD dengan melaksanakan 3M.Kata Kunci : DBD, Breeding Place dan Resting Place  Abstract             The existence of breeding place and resting place mosquitoes is a contributing factor to the increase of the DBD vector of the snake because if more and more breeding place holds water around and inside the house then it becomes a chance for mosquitoes Spawn and breeding, thereby increasing the risk of DBD events. Dengue Fever disease (DBD) is one of the problems of public health in Indonesia that tends to increase the number of sufferers and the wider spread. This research aims to determine the relationship of breeding place and resting place with DBD events in the village Kalosi district of Alla.    The type of research conducted is observational analytic with case control research design which is directed to explain a circumstance or situation that is done by comparing between case group with control group. The Instrument used in this study used a questionnaire with a case sample of 15 control 15 respondents.There is a relationship link between the existence of breeding place with dengue fever occurrence in the village of Alla subdistrict Kalosi with a P value of .000(OR=21.79 CI= 8.38-56.66) , there is a relationship between The existence of resting place with dengue fever occurrence in the village Kalosi District Alla with P value .000 (OR=11.56, CI= 5.08-26.31). Expected for the community to participate in the efforts to eradicate the Mosquito Nest Dengue fever (PSN-DBD). To the Puskesmas officers conduct routine checkups routinely 3 months, the implementation of fogging and improving health promotion to the public on how to prevent DBD by implementing 3M.Keywords: DBD, Breeding Place and Resting Place

scholarly journals Association between hyperemesis gravidarum and psychological symptoms, psychosocial outcomes and infant bonding: a two-point prospective case–control multicentre survey study in an inner city setting

BMJ Open ◽  
2020 ◽  
Vol 10 (10) ◽  
pp. e039715
Author(s):  
Nicola Mitchell-Jones ◽  
Kim Lawson ◽  
Shabnam Bobdiwala ◽  
Jessica Alice Farren ◽  
Aurelio Tobias ◽  
...  
Keyword(s):  
Mental Health ◽  
Data Collection ◽  
Hyperemesis Gravidarum ◽  
Case Control ◽  
Psychological Morbidity ◽  
Survey Study ◽  
Secondary Outcome ◽  
Control Group ◽  
Case Group ◽  
Probable Depression

ObjectivesTo assess if there is any association between hyperemesis gravidarum (HG), psychological morbidity and infant bonding and to quantify any psychosocial consequences of HG.DesignTwo-point prospective case–control, multicentre survey study with antenatal and postnatal data collection.SettingThree London hospitals.ParticipantsPregnant women at ≤12 completed weeks gestation recruited consecutively over 2 years. Women with HG were recruited at the time of admission; controls recruited from a low risk antenatal clinic. 106 women were recruited to the case group and 108 to the control. Response rates at antenatal data collection were 87% and 85% in the case and control groups, respectively. Postnatally, the response rate was 90% in both groups.Primary and secondary outcome measuresPrimary outcomes were psychological morbidity in the antenatal and postnatal periods, infant bonding in the postnatal period and psychosocial implications of HG. Secondary outcomes were the effects of severity and longevity of HG and assessment of correlation between Edinburgh Postnatal Depression Scale scores and maternal-to-infant bonding scores.ResultsAntenatally, 49% of cases had probable depression compared with 6% of controls (OR 14.4 (5.29 to 39.44)). Postnatally, 29% of cases had probable depression versus 7% of controls (OR 5.2 (1.65 to 17.21)). There was no direct association between HG and infant bonding. 53% of women in the HG group reported needing four or more weeks of sick leave compared with 2% in the control group (OR 60.5 (95% CI 8.4 to 2535.6)).ConclusionsLong-lasting psychological morbidity associated with HG was evident. Significantly more women in the case group sought help for mental health symptoms in the antenatal period, however very few were diagnosed with or treated for depression in pregnancy or referred to specialist perinatal mental health services. HG did not directly affect infant bonding. Women in the case group required long periods off work, highlighting the socioeconomic impact of HG.

Faktor-Faktor Determinan yang melatar belakangi Kehamilan Remaja di Desa Pandansari Kecamatan Poncokusumo Kabupaten Malang

2020 ◽  
Vol 7 (2) ◽  
pp. 247-255
Author(s):  
Maria Magdalena Setyaningsih ◽  
Emy Sutiyarsih
Keyword(s):  
Sex Education ◽  
Teen Pregnancy ◽  
Teenage Pregnancy ◽  
Well Being ◽  
Case Control ◽  
Control Group ◽  
Case Group ◽  
The Family ◽  
History Of ◽  
First Time

Kehamilan remaja adalah kehamilan yang terjadi pada remaja berusia kurang dari 20 tahunan. Kehamilan remaja memberikan banyak kerugian bagi kesehatan, mental dan psikologis, kesejahteraan ekonomi dan peluang karier, kemiskinan dan prospek kehidupan masa depan remaja. Tujuan penelitian mengidentifikasi faktor determinan yang melatarbelakangi terjadinya kehamilan remaja. Jenis penelitian adalah penelitian analitik kategorik jenis survei kuantitatif dengan desain case control. Populasi semua perempuan yang bertempat tinggal di wilayah dusun Wonosari, Sukosari, dan Krajan Pandansari dan pernah/sedang hamil pertama kali pada usia kurang dari 20 tahun. Teknik pengambilan sampel cluster random sampling besar sampel 73. Berdasarkan hasil model akhir analisis multivariat, diketahui bahwa variabel pendidikan, riwayat kehamilan remaja pada keluarga dan usia menikah merupakan variabel yang berhubungan dengan kejadian kehamilan remaja setelah dikontrol oleh variabel akses informasi, responden berpendidikan rendah memiliki peluang 20,8 kali lebih tinggi, responden yang memiliki riwayat kehamilan remaja pada keluarga memiliki peluang 14,9 kali lebih tinggi, responden yang menikah pada usia <20 tahun memiliki peluang 12,1 kali lebih tinggi, responden dengan pemahaman yang kurang baik terkait penggunaan kondom memiliki peluang 5,9 kali lebih tinggi untuk terjadi kehamilan remaja. Oleh karena itu perlu dibangun karakter buiding, sosial karakter suport untuk para ibu remaja dan keluarga sehingga terbangun interaksi yang baik dalam keluarga yang dilandasi dengan pendidikan dan pemahaman yang baik tentang Pendidikan seksualitas. Teen pregnancy is a pregnancy that occurs in adolescents aged less than 20 years old. Teen pregnancy provides many disadvantages for health, mental, psychological, economic well-being, career opportunities, poverty, and the future life. The aim of the study was to identify the determinants underlying teen pregnancy incidence. This study was a quantitative study with categorical analytic method. The study design used a case control with two comparison groups. The groups were control group and case group. The population in this study was all women who lived in the Wonosari, Sukosari, and Krajan Pandansari district and had or were pregnant for the first time at the age of less than 20 years old. Seventy three respondents were recruited using cluster sampling technique. The case group consists of women who were or had pregnant for the first time at the age of less than 20 years old and their children are currently aged ≤ 1 years old. The control group consists of women who were pregnant for the first time at the age of > 20 years old. The data was collected using a questionnaire. The findings showed that education, history of teen pregnancy in family and the age of marriage were related to the incidence of teen pregnancy after being controlled by information access. Low-educated respondents had 20.8 times higher chance of experiencing teen pregnancy; respondents with a history of teen pregnancy in the family had 4.9 times higher chance of experiencing teen pregnancy; respondents who were married at the age of < 20 years old had 12.1 times higher chance of experiencing teen pregnancy; respondents with poor understanding of condom use had 5.9 times higher chance of teenage pregnancy. In conclusion, the findings suggest to build good interactions in the family based on education and a good understanding of sex education.

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