Influence of Single-Digit Exclusions on Grip Strength in Healthy Male Adults

2021 ◽  
pp. 229255032110555
Author(s):  
Krishnakumar Sankar ◽  
Jobin Christ
Keyword(s):  
Grip Strength ◽  
Repeated Measures ◽  
Pearson Correlation ◽  
Statistical Significance ◽  
Human Hand ◽  
P Value ◽  
Hand Dominance ◽  
F Test ◽  
Single Digit ◽  
Age Range

Grip strength (GS) of the human hand is vital to deal with objects of various sizes and shapes in daily life. The strength deteriorates if one or more digits of the hand are amputated. The main aim of this study was to determine the influence of single-digit exclusions on the GS. Healthy adults ( n = 102, male) with an age range of 20 to 70 years (mean ± SD, 31.92 ± 13.14 years) participated in the study. The movements of unused digits were restrained using splints to avoid digit enslaving effects. T (Thumb), (I) Index, M (Middle), R (Ring), L (Little) digits were chosen for exclusion based on the digit configurations. The digit configurations were IMRL, MRLT, IMRT IRLT and, IMLT with exclusions T, I, L, M, and, R respectively. The results of two-way ANOVA with repeated measures showed no significant interaction ( p = 0.923) between hand dominance and digit configurations. But statistical significance ( p = 0.000) was observed in digit configurations and hand dominance individually. The results of posthoc analysis using Bonferroni corrected pairwise comparisons showed no statistical significance ( p = 0.004) between IRLT and IMLT of both hands since the corrected p-value was 0.003. The outcomes of the F-test showed no statistical significance ( p > 0.05) between the digit configurations IMRLT, IMRL; IMRL, MRLT; MRLT, IMRT; IRLT, IMLT individually within dominant (D) and non-dominant (ND) hands. When the F-test was performed using the same digit configurations between both hands, statistical significance was not observed in all the configurations except IMLT ( p < 0.05). The results of the Pearson correlation of GS were observed to be very strong between the same digit configurations of D and ND hands.

scholarly journals Alterations in gait velocity and grip strength of stroke survivors following a 12-week structured therapeutic exercise programme

2018 ◽  
Vol 10 (1) ◽  
pp. 76-80 ◽  
Author(s):  
Hammed I. Adebisi ◽  
Adodo S. Monikhe ◽  
Agwubike E. Okey
Keyword(s):  
Grip Strength ◽  
Repeated Measures ◽  
Statistical Significance ◽  
Exercise Programme ◽  
Training Data ◽  
Gait Velocity ◽  
P Value ◽  
Stroke Survivors ◽  
Therapeutic Exercise ◽  
Hemiparetic Stroke

Summary Study aim: This study investigated the alterations in gait velocity and grip strength of stroke survivors following a structured therapeutic exercise programme (STEP). Material and methods: This was a pre-test, post-test experimental study of the effectiveness of a 12-week STEP on gait veloc­ity and grip strength of stroke survivors. A total of 30 hemiparetic stroke survivors participated in the study. The instrument for this study was an adaptation of a training protocol for the training and assessment of gait velocity and grip strength. The participants underwent a 12-week STEP of a frequency of 3 times per week and the training programme focused on exercises aimed at improving the gait velocity and grip strength of the participants. The gait velocity and grip strength were measured before and after the training. Data generated were analysed using descriptive statistics of mean and standard deviation to sum­marize the profile of the participants. The analysis of variance for repeated measures (ANOVA) was used to test the hypotheses. Statistical significance was accepted for a p value of <0.05. Results: The outcome of this study showed that the STEP had significant (p < 0.05) effects on the gait velocity and grip strength of stroke survivors. Meanwhile, there was no significant (p > 0.05) effect of haemorrhagic and ischaemic groups of stroke sur­vivors on gait velocity and grip strength.Conclusion: It was therefore concluded that the use of the STEP can substantially improve the gait velocity and grip strength of stroke survivors.

scholarly journals Adolescent Pitcher Fatigue: Ulnar Collateral Ligament Stress, Flexor-Pronator Mass Energy Depletion, and Correlation to Pitch Count

2021 ◽  
Vol 9 (7_suppl4) ◽  
pp. 2325967121S0024
Author(s):  
Manuel Schubert ◽  
Tariq Awan ◽  
Aaron Sciascia ◽  
Emily Pacheco ◽  
Jennifer DeMink ◽  
...  
Keyword(s):  
Grip Strength ◽  
Muscle Glycogen ◽  
Repeated Measures ◽  
Statistical Significance ◽  
Ulnar Collateral Ligament ◽  
Glycogen Storage ◽  
Collateral Ligament ◽  
Time Points ◽  
Subjective Fatigue ◽  
Forearm Flexor

Objectives: There has been a rise in elbow ulnar collateral ligament (UCL) injuries in youth pitchers over recent years. With forearm flexor-pronator mass fatigue, the dynamic stability provided could be diminished placing greater stress on the UCL. Pitch count limits have been instituted in an attempt to help curtail this rise in throwing injuries, especially in youth athletes. In order to provide more objective data regarding current pitch count limits for youth pitchers, the purpose of this pilot study was to evaluate for potential fatigue of the flexor-pronator mass by assessing changes in medial elbow laxity, noninvasively characterizing changes in muscle glycogen storage within the forearm flexor-pronator mass, and evaluating changes in subjective fatigue, strength, range of motion (ROM), pitching velocity, and accuracy with increasing number of pitches thrown by 10-year-old pitchers up to their recommended 75 pitch count limit. Methods: After appropriate power analysis, male pitchers 10 years of age were recruited for the study (n=22). Pitchers threw a total of 75 pitches divided into sets of 25 pitches, with standardized periods of rest in between throws and sets to best simulate a game. Bilateral medial elbow laxity was measured by applying 10 decanewtons of valgus force with a standardized stress device and utilizing ultrasound imaging (Figures 1A-B) prior to pitching and after each pitching set. The change in medial ulnohumeral joint distance (Figure 1C) after stress was applied was calculated from baseline without stress. Relative changes in muscle glycogen storage, detected as changes in echogenicity, within the flexor carpi radialis (FCR) and the flexor digitorum superficialis (FDS)/flexor carpi ulnaris (FCU) muscles were measured non-invasively with ultrasound-based software (Figures 1D-E) and recorded as fuel percentile. Repeated measures analysis of variance and post-hoc testing were used to determine statistical significance (alpha=0.05). Results: There were no significant differences in medial elbow laxity between arms or time points. There was a trend for similar decline in FCR fuel percentile values between each arm, indicating relative decreases in glycogen storage bilaterally. However, only the throwing arm demonstrated a statistically significant decline in fuel percentile from baseline to after 75 pitches (p=0.05). There were no statistically significant differences across time points for FDS/FCU fuel percentile values. Fatigue measurements for both arms were significantly higher at all time points compared to baseline (p≤0.03). Grip strength of the dominant arm after 75 pitches was significantly decreased compared to after 25 pitches (p=0.02). There were no statistically significant changes in other strength measurements, ROM, velocity, or accuracy between all time points. Conclusions: By the recommended 75 pitch count limit in 10-year-olds, subjective fatigue and a decrease in grip strength had occurred. Furthermore, relative glycogen storage of the flexor-pronator mass of the throwing arm decreased between pitching 50 to 75 pitches, but without an increase in medial elbow gapping. This study provides a foundation and raises questions for further objective testing of physiologic changes that occur throughout increasing pitching to better guide pitch count limits and ensure the safety of young athletes

scholarly journals ULTRASOUND PREDICTABILITY OF LOWER UTERINE SEGMENT CESAREAN SECTION SCAR THICKNESS

2020 ◽  
pp. 9-11
Author(s):  
Madhu Kumari ◽  
Kumari Bibha ◽  
Abha Sinha ◽  
Debarshi Jana
Keyword(s):  
Cesarean Section ◽  
Gestational Age ◽  
Statistical Significance ◽  
P Value ◽  
Chi Square ◽  
Medical College ◽  
Chi Square Test ◽  
Uterine Scar ◽  
Age Range ◽  
The Given

Objective: The objective of this study is to find out association between scar thickness, assessed sonographically, and intraoperative findings (IOF). Study Design: Descriptive study. Place and Duration of Study: Department of Obstetrics and Gynecology, Sri Krishna Medical College and Hospital, Muzaffarpur, Bihar from June 2019 to May 2020. Methodology: A total of 70 pregnant patients were included in this study. Transabdominal ultrasound was done for scarred uteri. Sonographic findings were co-related with introperative findings. All the given data were entered on SPSS version 23. Age was expressed as mean ± SD. Parity, gestational age, and interval between cesarean sections were expressed as frequencies with percentages. Statistical analysis was done by using Chi-square test for categorical data for association between sonographic scar thickness and intraoperative findings. The statistical significance was set at p-value <0.05. Results: The age range of the patients was 20- 36 years with a mean of 27.91 ±3.690 years. Gestational age at the time of cesarean section was between 27-40 weeks of gestation with a mean of 37 ±2.126 weeks. The interval from previous cesarean was 10 months at the minimum, and 6 years at the maximum with a mean of 2.29 ±1.0 months. Mean scar thickness was 2.5 mm. Association between scar thickness (<1-3 mm) and intaoperative findings of dehiscence and rupture showed a p-value of <0.001. Conclusion: Sonographic assessment of a uterine scar has a practical application to determine the thickness of previous scar, and assess its integrity.

Important Role of B2-Glycoprotien in Females with Recurrence Abortion

2018 ◽  
Vol 9 (01) ◽  
Author(s):  
Ahmed Abbas Hasan ◽  
Radhia Hussain Fadel ◽  
Saeed Hilal Khudhair ◽  
Doaa Hashim Jawad
Keyword(s):  
Pearson Correlation ◽  
Mean Value ◽  
Enzyme Linked Immunosorbent Assay ◽  
Control Group ◽  
P Value ◽  
Recurrent Abortion ◽  
Significant Difference ◽  
Medical City ◽  
And Gender ◽  
Age Range

Recurrent abortion consider as one of the most common problem in world. There are different causes associated with recurrent abortion, these may be occur due to complication of microorganism infection or associated with immunological disturbance like abortion caused by Anti-phospholipid syndrome, or associated with SLE. The anti-b2glucoprotien antibodies have a role in abortion. In this study, we wish to determine whether there is a relationship between the levels of these anti-b2glucoprotien antibodies and abortion. Thirty females patients with spontaneous abortion (10 of them with Antiphospholipid syndrome,10 of them with systemic lupus erthymatosus and final 10 with toxoplasmosis with ages ranged between (20-46) where taken from (Al-Hussein Medical City/Kerbala). Control group consisted of 20 healthy people who were free from history of abortion who matched in age and gender with patients. B2gp(IgMandIgG) EASIA Kit, generic assay) and was studied using the enzyme-linked immunosorbent assay (ELISA) method. T-test and ANOVA and Pearson correlation used to analyze results by using SPSS version 24. P-value ≤ 0.05 was considered significant. The patients with age range blow 30 years show high percent(63.3%) among the other groups .most of the patients have high percent of 3 times abortion were reported in all different groups .The mean value of anti-B2gP-I IgG (45.354) show highly a significant difference results in aborted patients with APS and significant difference in patients with SLE when compared with controls groups. the Anti-B2gPI IgM not give statistically significant difference when camper to health cases. we conclude that the Anti-B2GPI IgG levels were increased significantly in aborted females with APS and SLE .

Safety profile of ripretinib, including impact of alopecia, and Palmar-Plantar Erythrodysesthesia Syndrome (PPES) on patient-reported outcomes (PROs), in ≥ fourth-line advanced gastrointestinal stromal tumors (GIST): Analyses from INVICTUS.

2020 ◽  
Vol 38 (15_suppl) ◽  
pp. 11539-11539
Author(s):  
Suzanne George ◽  
Michael C. Heinrich ◽  
John Raymond Zalcberg ◽  
Sebastian Bauer ◽  
Hans Gelderblom ◽  
...  
Keyword(s):  
Safety Profile ◽  
Repeated Measures ◽  
Fixed Effects ◽  
Statistical Significance ◽  
P Value ◽  
Tolerability Profile ◽  
Patient Reported ◽  
The Impact ◽  
Advanced Gist ◽  
Over Time

11539 Background: Ripretinib is a novel switch-control TKI that broadly inhibits KIT and PDGFRA kinase signaling. In INVICTUS (NCT03353753), a randomized, double-blind, placebo (PBO)-controlled trial of ripretinib in ≥4th-line advanced GIST, ripretinib reduced the risk of disease progression or death by 85% vs PBO with a favorable overall safety profile. Common ( > 20%) adverse events (AEs) included, but were not limited to, alopecia and PPES. Exploratory analyses evaluated the impact of alopecia and PPES on quality of life (QoL). Methods: Patients (pts) with advanced GIST previously treated with at least imatinib, sunitinib, and regorafenib were randomized (2:1) to ripretinib 150 mg QD or PBO. AEs were graded using CTCAE v4 and PROs collected using EQ-5D-5L (EQ5D) and EORTC QLQ-C30 (C30). Repeated measures (RM) models assessed the impact of alopecia and PPES on 5 PROs (EQ5D visual analogue scale; and C30 physical functioning, role functioning, and the overall health and overall QoL questions) within the ripretinib arm. Fixed effects were sex, alopecia/PPES, and ECOG scores at baseline. Results: 128/129 randomized pts received treatment (85 ripretinib 150 mg QD; 43 PBO). Alopecia, regardless of causality, occurred in 44 (51.8%) on ripretinib (34 [40.0%] grade 1; 10 [11.8%] grade 2) and 2 (4.7%) on PBO (both grade 1). PPES occurred in 18 (21.2%) on ripretinib (11 [12.9%] grade 1; 7 [8.2%] grade 2); none on PBO. The median times in days to first occurrence and worst severity grade with ripretinib were 57.0 and 62.5 for alopecia; 56.5 and 57.0 for PPES. The RM models showed a slight trend towards improvement in PRO score over time for pts with alopecia; the only association reaching a P-value of < 0.05 was between alopecia and increased overall QoL. None of the associations between PPES and PRO scores reach P < 0.05. All PRO p-values are nominal, and no statistical significance is being claimed. Conclusions: Ripretinib had a favorable overall safety and tolerability profile. When stratified by alopecia and PPES, patient-reported assessments of function, overall health, and overall QoL were maintained over time. For both alopecia and PPES, onset and maximum severity occurred almost simultaneously, indicating that these events generally did not progressively worsen. These results suggest that alopecia and PPES are manageable and do not have a negative effect on function, overall health, and QoL. Clinical trial information: NCT03353753 .

Same Day Dosing of Pegfilgrastim in Elderly Patients Receiving Fractionated Dose Chemotherapy.

Blood ◽  
2004 ◽  
Vol 104 (11) ◽  
pp. 2215-2215
Author(s):  
Larry Y. Watt ◽  
Istvan Redei ◽  
Robert D. Levin ◽  
Joel Granick ◽  
Rakhshanda Neelam ◽  
...  
Keyword(s):  
Elderly Patients ◽  
Statistical Significance ◽  
Stage Iv ◽  
Severe Neutropenia ◽  
Control Group ◽  
P Value ◽  
Concurrent Administration ◽  
Patient Demographics ◽  
Stage Iv Cancer ◽  
Age Range

Abstract Background: We have previously reported that same day dosing (SDD) of pegfilgrastim (PG) did not result in an increased incidence of negative outcomes as compared to filgrastim (G) administered the next day. (Watt et al. Pharmacotherapy. 2003;23:406. #105). Age (≥ 65 years) is known to be a risk factor for febrile neutropenia in patients undergoing myelosuppressive chemotherapy. Purpose/Methods: This study aims to assess the efficacy and safety of SDD of PG among older cancer patients for severity of neutropenia (grade 4), infection/neutropenia- related hospitalization, incidence of delayed administration (or dose reduction) of chemotherapy or any unplanned MD visits due to leukopenia (table). G administered subsequent to chemotherapy served as the control group. Patients ≥ 65 years with solid tumors who received fractionated dose chemotherapy at our institution between January 2001 and March 2004 were reviewed retrospectively. Patients who received chemotherapy initially at substandard doses were excluded. Results: Patient demographics indicated that the two groups were evenly matched, with similar mean baseline absolute neutropenic counts (ANC). Distribution of cancer diagnoses is as follows: PG: breast (7), lung (8), GI (18) and others (2); G: breast (5), lung (9), GI (7) and others (4). Twenty-six (87%) and 21 (84%) patients had stage IV cancer in the PG and G groups, respectively. The mean ANC nadirs for PG and G were 2790±2190 cells/mm³ and 1820±1930 cells/mm³, respectively (p=0.01). For the outcome endpoints, although certain trends seemed to favor SDD of PG, none of the odd ratios (OR) performed reached statistical significance. Doses of PG and G were generally well-tolerated by all patients. Conclusion: Concurrent administration of PG showed safety and efficacy at least comparable to G in elderly patients receiving fractionated dose chemotherapy. Such administration schedule has the potential to further simplify the outpatient management of chemotherapy-induced neutropenia, providing the needed convenience for elderly patients as well as caregivers. However, further prospective study is warranted. PG G p-value; OR (95% CI) data were analyzed based on cycles No. patients 30 25 No. cycles 59 54 Age (range) 68.8 (65–79) 68.3 (65–72) Gender (female) 18 (60%) 15 (60%) ANC before chemo±SD(cells/mm³) 4530±1850 4790±2600 p=0.539 ANC nadir±SD (cells/mm³) 2790±2190 1820±1930 p=0.01 Severe Neutropenia (grade IV) 9 (15%) 15 (28%) OR=0.47; (0.19, 1.18) Unplanned MD visit 7 (12%) 3 (5.6%) OR=2.28; (0.56, 9.34) Chemo delayed/dose reduced 9 (15%) 11 (20%) OR=0.70; (0.27, 1.86) Hospitalization 7 (12%) 5 (9.3%) OR=1.32; (0.39, 4.44)

scholarly journals P0012SHOULD WE DEFINE A NEW STANDARD PRESCRIPTION OF BICARBONATE (HCO3-) IN HEMODIALYSIS (HD)?

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Ana Rita Valerio Alves ◽  
Cátia Figueiredo ◽  
HernÂNi Ricardo Martins GonÇAlves ◽  
Karina Lopes ◽  
Flora Sofia ◽  
...  
Keyword(s):  
Renal Disease ◽  
Repeated Measures ◽  
Statistical Significance ◽  
Small Sample ◽  
Categorical Variables ◽  
Blood Levels ◽  
P Value ◽  
Disease Etiology ◽  
Time Points ◽  
Time Point

Abstract Background and Aims One of the aims of the regular, intermittent HD therapy prescribed for patients with end-stage chronic kidney disease, is correction of metabolic acidosis by addition of HCO3- to dialysate fluid. The KDOQI guidelines therapeutic goal is to maintain pre-dialysis HCO3-≥22mmol/L. The aim of the study was to evaluate an individualized HCO3-hemodialysis prescription as a preventing factor of metabolic changes in a HD facility and define a new standard HCO3-prescription. Method 36-month prospective study of patients on online high-flux hemodiafiltration. Every 3 months (13 time points) HCO3-, Calcium (Ca2+), Phosphorus (P+), intact Parathyroid hormone (iPTH) and protein C reactive (PCR) blood levels were analyzed. HCO3-prescription was changed using the following rules: The data collected comprised demographic information, renal disease etiology, comorbidities, HD treatment information and lab results. Categorical variables are presented as frequencies and percentages, continuous variables as means and standard deviations, or medians and interquartile ranges (IQR) for variables with skewed distributions. A p-value&lt;0.05 was considered statistically significant. Statistical analysis was performed using SPSS version 23 for Mac OS X. Results From the 50 patients that were evaluated at Time point 0, only 24 patients completed the follow-up period. Sixteen (66.7%) were males, 54.2% (n=13) diabetic and 58.3% (n=14) hypertensives and the median age was 76 years (IQR 13). At baseline (time point 0), median pH was 7.4 (IQR 0.09) and serum HCO3-26.5 mmol/L (IQR 2.32). At time point 12, pH was 7.35 (IQR 0.12) and serum HCO3-23.25mmol/L (IQR 1.93). A repeated measures ANOVA determined that prescribed HCO3- differed with statistical significance during time (F(2.787,83.308)=39.055, p=0.001), and the post Hoc tests confirmed those assumptions between time point 1 and all the others time points, as an example the mean difference between initial prescribed HCO3-and time point 12 was 5.39mmol/L (p=0.001). Wilcoxon Sign-Rank Tests determined that throughout the analyzed period the serum HCO3- approached the reference serum HCO3- (23mmol/L) that we have defined as ideal (at time point 0, median=26.5mmol/L, Z=4.144, p=0-001; at time point 12, median 23.25mmol/L, Z=1.243, p=0.214). On the other hand, a one sample T-Test determined that the HCO3- prescription differed more in each time point from the 32mmol/L defined as standard (at time point 12, t=-2.798, p=0.01) and approached a new suggested value of 26mmol/L. However, at time point 8, 62.5% (n=15) patients had a HCO3-prescription of 28mmol/L, (t(23)=0.001,p=1) and at that time we had hypothesized that that a prescription of 28 mmol/L should be the new standard. Gender, Diabetes Mellitus, Hypertension, and renal disease etiology did not influence the HCO3- prescription neither serum HCO3-. Conclusion HCO3-prescription and serum HCO3- were not influenced by comorbidities like DM and Hypertension. Our findings suggest that the standard HCO3- prescription of 32mmol/L should be rethought, as an individualized HCO3- prescription could be beneficial for the patient. At this time, we suggest that a prescription of 26 mmol/L should be the new standard. However, the limitations of our findings include the small sample size, so further studies with larger samples should be attempted.

scholarly journals Differential GFR estimation of the double moiety kidneys by modified GATE’S formula

2021 ◽  
Vol 3 (3) ◽  
pp. 01-05
Author(s):  
Sivasubramaniyan V
Keyword(s):  
Gamma Camera ◽  
Pearson Correlation ◽  
P Value ◽  
Mean Values ◽  
Nephron Sparing ◽  
Two Samples ◽  
Significant Difference ◽  
The Mean ◽  
The Individual ◽  
Age Range

Aim: This retrospective analysis of the GFR values of the individual moieties obtained by using a novel software with modified GATE’S formula in the in house software created at SSSIHL, compared and evaluated with the value derived by the combined GFR value of the single kidney GFR as obtained from the Icon software loaded in the gamma camera. Materials and Method: This retrospective study of 10patients diagnosed with unilateral double moiety and 5 patients with bilateral duplication was undertaken to validate the modified GATE’S formula in house software created at SSSIHL. This group had 12 males in the age range of 03-66 years with the mean age of 26.5 ± 2 years and 3 females in the age range of 29 – 31 years with mean age of 31 ± 2 years. Renal scans were done using Siemens dual head gamma camera (E.CAM). The radiopharmaceutical 99mTc-DTPA 5 mCi was injected as a bolus intravenously for the adult patients and 3 mCi was injected for the children. The images were obtained and processed by using GFR/Renal differential processing protocol in icon software. Later the raw data of the scan study transferred to the workstation loaded with the in house software created at SSSIHL with modified GATE’S formula created by us. The individual moiety GFR values were calculated using the software with modified Gate’s formula developed in MATLAB GUI algorithm and tabulated. Then the combined value of individual moiety GFR values compared with that of the individual whole kidney GFR value obtained by the Icon software protocol. Result: The T test evaluation done in the online statistical calculator of Maths Portal org revealed that the mean values of the two groups showed no significant difference at p < 0.05. The calculated t value is smaller than the critical value (0.0217 < 2.024), so the means are not significantly different. Pearson Correlation performed between the above two samples using statistical online calculators also showed the correlation coefficient of r = 0.9247 and a mean difference of 0.09 indicating that the high correlation between them. The observed significance p value < 0.0001 at t value of 10.27, showed no significant difference detected between the two samples. Conclusion: It can be concluded that the in house software created at SSSIHL with modified GATE’S formula method of GFR calculating software showed identical values with that of the GFR calculated with the original Gate’s formula. This was found to be useful in calculating the GFR of individual moieties separately in the cases of Double moieties in both Unilateral and Bilateral involvement effectively. The utility and usefulness of the separate estimation of individual moieties GFR needed for Nephron Sparing Surgery.

scholarly journals A study on knowledge regarding different aspects of injection safety among injection providers at different levels of health care

2017 ◽  
Vol 4 (5) ◽  
pp. 1737
Author(s):  
Uroosa Farooq Allaqband ◽  
Anjum B. Fazili ◽  
Rohul Jabeen Shah ◽  
Ab. Majid Ganai ◽  
Walied K. Balwan ◽  
...  
Keyword(s):  
Statistical Significance ◽  
Healthcare Providers ◽  
P Value ◽  
Cross Sectional ◽  
Healthcare Facilities ◽  
Definition Of ◽  
Unsafe Injection ◽  
Exposure Prophylaxis ◽  
Age Range ◽  
Injection Safety

Background: Estimates suggest that at least 50% of the world’s injections administered each year are unsafe, particularly in developing countries. Unsafe injection practices put patients and healthcare providers at risk of infectious and non-infectious adverse events, sound knowledge of healthcare providers is vital to break the chain of blood borne diseases transmission caused by unsafe injection practices.Methods: Cross sectional observational questionnaire based study was carried out amongst 152 injection providers of 40 healthcare facilities of two districts of Kashmir valley (one rural and one urban) selected purposively. Results are summarised and presented in the form of tables and chi (x2) test was used for test of association with statistical significance set at p-value of less than 0.05.Results: In this study out of 152 injection providers, majority (81.57%) were in the age range of 21-40 years and 74.3% were females. 43.4% of the participants were FMPHWs, 30.9% were nurses and 13.8% pharmacists. Overall 65.8% and 67.1% of injection providers had correct knowledge regarding WHO definition of safe injection and infections transmitted by unsafe injections respectively. Majority (90.8%) were aware about the biomedical waste management rules.Conclusions: We conclude that over all the knowledge of different aspects of injection safety was good among the participants except the poor knowledge ofpost exposure prophylaxis and disposal of injection related waste despite the use of color coded bags at the sites of waste generation. 

scholarly journals CORRELATION BETWEEN HRCT SCORE AND SERUM FERRITIN IN COVID-19 PATIENTS WITH PNEUMONIA IN TERTIARY CARE HOSPITAL, MGM HOSPITAL AURANGABA

2021 ◽  
pp. 52-54
Author(s):  
Saurabh Govind Pad ◽  
Devidas Dahiph ◽  
Saurabh Kakani ◽  
Vimal Dugad
Keyword(s):  
Serum Ferritin ◽  
Pearson Correlation ◽  
Tertiary Care ◽  
P Value ◽  
Care Hospital ◽  
The Social ◽  
Severe Group ◽  
Positive Correlations ◽  
Age Range

This study was aimed to correlate the HRCT score and serum ferritin in diagnosed cases of COVID19 patients with pneumonia.During the pandemic of COVID-19,there was sudden surge in the numbers of HRCT chest scans and along with this amongst the various laboratory investigations serum ferritin was done to observe the role of cytokines which helps in disease progression.The main purpose of this study was to correlate the severity of disease on HRCT chest scan with serum ferritin levels. Aim:To correlate the HRCT score and serum ferritin in diagnosed cases of COVID19 patients with pneumonia. Materials and methods: We included 59 patients (38 men, 21 women age range 18-78years) with documented COVID19 were reviewed. All patients underwent RTPCR tests and had a noncontrast HRCT scan done at presentation. Estimation of serum ferritin was analyzed by using chemiluminescence method.The subjects were divided into three groups:mild,moderate and severe on the basis of HRCT score. Each group's HRCT score correlated with serum ferritin. The details were recorded on a prestructured proforma. The Pearson correlation coefficient test was used for correlations, and p value less than 0.05 was defined as statistically significant.The data was analyzed using Statistical Package for the Social Sciences (SPSS). Results: Out of 59 patients,21 patients were included in the mild group,31 were included in the moderate group and 7 were included in the severe group.CT severity score was found to be positively correlated with ferritin levels (p < 0.001). Strong positive correlations were found between CT scores and serum ferritin in mild (r = 0.84),Moderate (r = 0.92) and severe group (r = 0.082)

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