scholarly journals Sex Differences in Statin Prescribing in Diabetic and Heart Disease Patients in FQHCs: A Comparison of the ATPIII and 2013 ACC/AHA Cholesterol Guidelines

2019 ◽  
Vol 6 ◽  
pp. 233339281882541
Author(s):  
Nazia Naz S. Khan ◽  
Karen Kelly-Blake ◽  
Zhehui Luo ◽  
Adesuwa Olomu
Keyword(s):  
Heart Disease ◽  
Heart Association ◽  
Atherosclerotic Cardiovascular Disease ◽  
Recommended Dosage ◽  
Men And Women ◽  
Outcomes Measures ◽  
Significant Difference ◽  
Quasi Experimental ◽  
The Difference ◽  
Cholesterol Guidelines

Purpose: The purpose of this study was to determine the difference in the rate of statin prescribing based on the Adult Treatment Panel (ATP) III and 2013 American College of Cardiology (ACC)/American Heart Association cholesterol guidelines across sex in Federally Qualified Health Centers (FQHCs), and to determine the proportion of patients on recommended statin dosage based on the 2013 cholesterol guideline. Methods: The Office Guidelines Applied to Practice (Office-GAP) study is a quasi-experimental, 2 FQHCs center study that enrolled patients with coronary heart disease and diabetes mellitus (DM). We computed 10-year atherosclerotic cardiovascular disease (ASCVD) risks scores based on ACC guidelines and determined the rate of statin prescribing across sex in FQHCs using both guidelines. Main outcomes measures were (1) rate of statin prescribing based on ATPIII and 2013 cholesterol guidelines across sex and (2) proportion of patients on recommended statin dosage based on the 2013 cholesterol guideline. Results: The 2013 cholesterol guideline did not increase the rate of eligibility of statin for men and women compared to ATPIII guideline. No significant difference between men and women in statin prescribing under ATPIII (67% vs 57%, P = .13) and 2013 cholesterol guidelines (66% vs 63%, P = .69) and in the recommended dosage of statin per the 2013 cholesterol guidelines between men and women in FQHCs (12% vs 22%, P = .22). Conclusions: We found statin underprescribing for both men and women with ASCVD and DM in FQHCs. Utilizing both the ATPIII and the 2013 cholesterol guidelines, men with ASCVD and DM were prescribed statin more than women. However, fewer men were found to be on the recommended dosage of statin based on the 2013 cholesterol guideline. Our findings suggest that Office-GAP may have improved the prescription/use of statin in both men and women.

Attention Deficit Hyperactivity Disorder, Creativity, and the Effects of Methylphenidate

PEDIATRICS ◽  
1993 ◽  
Vol 91 (4) ◽  
pp. 816-819
Author(s):  
Jeanne B. Funk ◽  
John B. Chessare ◽  
Michael T. Weaver ◽  
Anita R. Exley
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Attention Deficit ◽  
Repeated Measures ◽  
Creative Thinking ◽  
Adhd Group ◽  
Hyperactivity Disorder ◽  
Significant Difference ◽  
Quasi Experimental ◽  
The Difference ◽  
Clinically Significant

Given that children with attention deficit hyperactivity disorder (ADHD) are more impulsive than peers, this study explored whether they are correspondingly more creative, and whether creativity declines when impulsivity is decreased through methylphenidate (Ritalin) therapy. A repeated-measures quasi-experimental design was used to compare the performance of 19 boys with previously diagnosed ADHD and 21 comparison boys aged 8 through 11 on two administrations of alternate forms of the Torrance Tests of Creative Thinking-Figural (nonverbal). Boys with ADHD received prescribed methylphenidate only for the first session. Overall, mean Torrance summary scores for comparison boys (mean = 115.1, SD = 16.1) were higher than for boys with ADHD (mean = 107.6, SD = 12.7). However, the difference between means was small (7%) and did not meet the 25% criterion for a clinically significant difference. No changes in performance over time (comparison group) or medication state (ADHD group) were observed. These data suggest that, when measured nonverbally, the creative thinking performance of boys with ADHD is not superior to that of peers who do not have ADHD. Regarding the effects of methylphenidate, prescribed therapy did not influence performance on this measure of creative thinking.

Effect of Tobacco on Lipoprotein Profile: A Comparative study among Smokers and Chewers

2021 ◽  
pp. 4973-4976
Author(s):  
Roshan Kumar Jha ◽  
Ranjit S. Ambad ◽  
Priya Koundal ◽  
Akansha Singh
Keyword(s):  
Risk Factors ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Total Cholesterol ◽  
Sample Processing ◽  
Exclusion Criteria ◽  
Future Studies ◽  
Area Of Interest ◽  
Significant Difference ◽  
The Difference

It has been proved that tobacco is one of the cholesterol dependent risk factors pathogenically, and in addition with other risk factors it may lead to coronary heart disease. Thus, a strong interaction exists between hypercholesterolemia and tobacco ingesting in the genesis of coronary heart disease. The aim of this study was to study the effect of tobacco smoking and chewing and compare its effect on lipoproteins. 60 subjects were included in the study, and were grouped into 3 three groups, tobacco smokers, tobacco chewers and tobacco non-abusers. Each group comprises 20 participants: selected on the basis of inclusion and exclusion criteria. Proper sampling and sample processing methods were employed to evaluate lipid profile. Total cholesterol and triglycerides levels were increased in smokers in comparison to non-smokers/non-chewers, and the differences were significant p<0.0001. HDL level was decreased in smokers as compared to non-smokers/non-chewers and the difference was statistically significant p<0.0001. Total cholesterol and LDL levels were increased in smokers in comparison to chewers. HDL level was decreased in chewers as compared to chewers. There was no significant association in any of the parameters. Present study observed increased and significant p<0.0001 differences in levels of total cholesterol and triglycerides while, HDL levels were decreased significantly p<0.0001, and also observed there was no significant difference among tobacco smokers and chewers. This may be a new area of interest for future studies.

scholarly journals The Level of the Functional Movement Screen Among Traditional Dancers

2021 ◽  
Vol 17 (11) ◽  
pp. 103
Author(s):  
Segar A/L A. Maniveloo ◽  
Borhannudin Abdullah ◽  
Shamsulariffin Samsudin
Keyword(s):  
Descriptive Analysis ◽  
Rotational Stability ◽  
Functional Movement Screen ◽  
Stability Tests ◽  
Functional Movement ◽  
Risk Of Injury ◽  
Significant Difference ◽  
Quasi Experimental ◽  
The Difference ◽  
Deep Squat

Movement assessments are commonly used to assess athlete&rsquo;s risk of injury as well as basic and specific skill movement patterns; however, dance is identified to be differing from sports because the average dancer&rsquo;s training load is higher than the athletes. This study aims to identify the difference in the Functional Movement Screen (FMS) level among traditional dancers in Malaysia. A quasi-experimental study design was adopted, which involved 66 dancers (M = 33; F = 33). The study comprised traditional dancers from three ethnic backgrounds, namely, Malay, Chinese and Indian. The descriptive analysis described the level of the dancers&rsquo; FMS, as follows: Malay (M = 16.18, SD = 2.062), Chinese (M = 18.50, SD = 1.102), Indian (M = 18.23, SD = 1.445). The ANOVA analysis found a significant difference in the FMS scores among all three groups of dancers, F (2,63) = 14.026, p &gt;.000. The deep squat, hurdle step, shoulder mobility, active straight leg raise and trunk stability tests for push-up indicated a significant difference, whereas the inline lunges test and rotational stability tests showed no significance difference. However, the Post Hoc analysis showed no significant difference between the Chinese and Indian dancers. It can be concluded that there is a difference in FMS scores between Malay, Chinese and Indian dancers. FMS may be a useful tool to help identify dancers about the risk of injury and improve their movement quality.

scholarly journals The difference in saliva pH before and after brushing with fluoride containing toothpaste and without toothpaste

2008 ◽  
Vol 20 (3) ◽  
Author(s):  
Samuel Setiawan ◽  
Edeh Rolleta Haroen ◽  
Dede Hadidjah
Keyword(s):  
Drinking Water ◽  
Research Method ◽  
Control Group ◽  
Research Subjects ◽  
Male And Female ◽  
Significant Difference ◽  
Salivary Ph ◽  
Before And After ◽  
Quasi Experimental ◽  
The Difference

In administering fluoride through drinking water there is the risk of overdose, higher cost and inadequate availability of drinking water containing fluoride in developing countries like Indonesia. A safe fluoride source is contained in toothpaste. The purpose of this research was to obtain data concerning difference in saliva pH before and after brushing with toothpaste containing fluoride and without toothpaste. The research method used was the quasi-experimental method. Samples were collected by the way of purposive sampling, conducted on 43 male and female research subjects. The data were analyzed by statistical analysis using the t test at 95% confidence level. In this research a control group consisting of 43 people was used. Research results indicated that the average saliva pH before brushing was 7.174; after brushing with fluoride containing toothpaste salivary pH was 7.593. Result research of brushing without toothpaste showed an average saliva of 7.163 before brushing and 7.379 after brushing without toothpaste. The average changes in saliva pH before and after brushing using fluoride containing toothpaste was 0.216. The conclusion of this research was that there was significant difference in saliva pH before and after brushing with toothpaste containing fluoride; there was significant difference in saliva pH before and after brushing without toothpaste, and there was significant difference in saliva pH before and after brushing with toothpaste containing fluoride and without toothpaste.

scholarly journals Lower is better: ezetimibe and PCSK9 inhibition join the mainstream of lipid‑lowering therapy

2016 ◽  
Vol 7 (1) ◽  
pp. 17-25
Author(s):  
Cezary Wójcik
Keyword(s):  
Statin Therapy ◽  
Heart Association ◽  
Lipid Lowering ◽  
Atherosclerotic Cardiovascular Disease ◽  
Lipid Lowering Therapy ◽  
Pcsk9 Inhibitors ◽  
Level Of Evidence ◽  
Cholesterol Guidelines ◽  
Pcsk9 Inhibition ◽  
Current Guidelines

The focus of 2013 cholesterol guidelines to prevent atherosclerotic cardiovascular disease (ASCVD) released by American College of Cardiology (ACC) and American Heart Association (AHA) is the administration of high intensity statin therapy to specific four groups of patients, which were found to benefit the most from such therapy. They no longer promote achieving specific LDL-C goals with a combination therapy involving statins and other drugs, as advocated by the former ATP-III guidelines as well as current guidelines of European Atherosclerosis Society, International Atherosclerosis Society or National Lipid Association. Such approach has been dictated by the strict reliance on randomized controlled trials as the only acceptable level of evidence. However, since publication of the 2013 ACC/AHA guidelines, cardiovascular benefits of ezetimibe added to statin therapy have been established. Moreover, the advent of PCSK9 inhibitors, providing a powerful supplement and/or alternative to statin therapy, further complicates the therapeutic horizon in dyslipdiemias. It is very likely that a new set of ACC/AHA guidelines will be published in 2016, with a return of specific LDL-C and Non-HDL-C goals of therapy as well as integration of drugs other than statins. As the treatment of dyslipidemias becomes more complex, the need for the subspecialty of clinical lipidology to be officially recognized becomes more evident.

The effect of ear acupressure medicine at the “Shen Men” point on the nausea and vomiting during pregnancy

2021 ◽  
Vol 15 (5) ◽  
pp. 1774-1779
Author(s):  
Sanaz Nehbandani ◽  
Hajar Salehi ◽  
Khadije Rezaie Keikhaie ◽  
Hossein Rashki Ghalenow ◽  
Fatemeh Mirzaie ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Gestational Age ◽  
Intervention Group ◽  
Nausea And Vomiting ◽  
Control Group ◽  
Health Clinics ◽  
Significant Difference ◽  
Quasi Experimental ◽  
The Mean ◽  
The Difference

Introduction & Objective: Nausea and vomiting during pregnancy is one of the most common gastrointestinal disorders that more than 85% of pregnant women experience. However, controlling and treating this complication is still one of the most important issues in antenatal care. Therefore, the aim of this study was to investigate the effect of ear acupressure at Shen Men point on relieving nausea, vomiting and retching during pregnancy. Materials and Methods: In this quasi-experimental study, 100 pregnant women with a gestational age of less than 16 weeks attending the health clinics of Zabol city during 2019-2020 were studied in two control and intervention groups (n = 50 in each group). The samples in the intervention group were trained to apply pressure on their ears’ Shen Men point with the thumb for three minutes three times a day (morning, noon, and night), for a duration of one month. At the end of second and fourth weeks, the data were collected using the Rhodes index form and then, were analyzed by SPSS software version 22. Results: According to the results, there was no significant difference between the two groups in terms of age, gestational age, occupation and education. The difference in the mean scores of nausea, vomiting and retching was not statistically significant between the control and intervention groups before the study. But four weeks after the study, a significant difference was observed in the mean scores of vomiting, nausea and retching between the two groups, so that the mean scores of vomiting, nausea and retching were significantly lower in the intervention group than in the control group. Conclusion: The ear acupressure medicine at the Shen men point can be used as a non-invasive, safe and inexpensive method to relieve nausea, vomiting and retching during pregnancy. Keywords: Acupressure medicine, Shen Men, Vomiting, Pregnancy, Nausea, Retching, Rhodosis

Establishment of the Standardized Uptake Values of 99mTc-MDP in Normal Vertebrae for SPECT/CT Quantification

2020 ◽  
Author(s):  
Na Qi ◽  
Qingyuan Meng ◽  
Zhiwen You ◽  
Huiqian Chen ◽  
Yi Shou ◽  
...  
Keyword(s):  
Standardized Uptake Value ◽  
Female Group ◽  
Sample Population ◽  
Strong Negative Correlation ◽  
Men And Women ◽  
Male And Female ◽  
Ct Value ◽  
Standardized Uptake Values ◽  
Significant Difference ◽  
The Difference

Abstract PurposeTo establish the standardized uptake value (SUV) of Tc-99m-methylene diphosphonate (MDP) for normal vertebra in both Chinese male and female by using a SPECT/CT scanner.MethodsA retrospective study was carried out involving 116 men and 105 women who underwent SPECT/CT scan using 99mTc-MDP. We acquired the SUV, CT value of 2416 normal vertebra in total and analyzed the difference of SUV between men and women. We analyzed the vertebra data with no significant difference of SUVmax in male and female group. The correlations between SUVmax value and CT value, age, height, weight in each group were also analyzed.ResultsThe SUVmax, SUVmean of vertebra in men were markedly higher than those in women(P < 0.0009). Specifically, for males, the SUVmax of C1, C2-4 and C5-L5 vertebra appeared to have significant differences(P < 0.05), while no significant difference of the SUVmax of C1-L5 vertebra were observed in females(P < 0.05). The SUVmax of each vertebral segment showed a strong negative correlation with CT values in both men and women(r=-0.89,-0.92;P < 0.0009). The SUVmax of vertebra showed weak significant correlation with weight and height in male (r = 0.4,P < 0.0009;r = 0.28,P = 0.005),and weak significant correlation with weight in females(r = 0.32,P = 0.009).ConclusionThis article study initially established SUVmax, SUVavgmean of normal vertebra in both Chinese men and women with a large sample population,and summarized the SUVmax of vertebra with no significant difference. The results could provide a quantitative reference for clinical diagnosis and the evaluation of therapeutic response in vertebral lesions.

scholarly journals Beliefs About Medicines: Differences in cholesterol treatment adherence among the Visegrad countries

2019 ◽  
Vol 29 (Supplement_4) ◽  
Author(s):  
K Boruzs ◽  
Z Fekete ◽  
V Dombrádi ◽  
G Bányai ◽  
A Nagy ◽  
...  
Keyword(s):  
Lipid Lowering ◽  
The European Union ◽  
Cholesterol Lowering ◽  
Development Fund ◽  
Lipid Lowering Drugs ◽  
Beliefs About Medicines ◽  
Significant Difference ◽  
The Difference ◽  
Cholesterol Guidelines ◽  
Visegrad Group

Abstract Background Raised cholesterol is a risk factor for cerebrovascular and cardiovascular diseases. New cholesterol guidelines highlight more personalized risk assessments and new cholesterol-lowering drugs for people at the highest risk for cardiovascular disease. Methods The aim of our study was to investigate the possible differences in the beliefs about the necessity and concerns regarding lipid-lowering drugs among the Visegrad Group countries. For this the Beliefs About Medicines Questionnaire (BMQ-Specific) was used. The statistical analyses included 235 Czech, 205 Hungarian, 200 Polish, and 200 Slovak respondents, all of who were taking cholesterol lowering drugs. Results After comparing the answers of the citizens of the Visegrad Group countries, no statistically significant difference could be found regarding the concerns about the lipid-lowering drugs. However, related to the beliefs in necessity, a significant difference was shown between Poland and Hungary for the benefit of Polish participants. These results suggest, that the citizens of Visegrad Group countries do not differ regarding their beliefs about the fear of the treatment, while the beliefs about benefits are the most emphasized among the Polish citizens and less among the Hungarian citizens. Conclusions While policy makers in the Visegrad Group countries can use the same strategy to address the concerns regarding cholesterol lowering medication, the reasons behind the difference in the beliefs in necessity should be further investigated in order to implement country specific interventions. The research was funded by the GINOP-2.3.2-15-2016-00005 project which is co-financed by the European Union under the European Regional Development Fund. Key messages No differences exist regarding the concerns for cholesterol lowering medication among the Visegrad Group countries. Concerning necessity significant differences were observed among the same countries, which prompts further research questions.

scholarly journals PENGARUH TERAPI MUROTTAL TERHADAP TINGKAT KONSENTRASI SISWA KELAS VIII. G DI MTSN 2 MUARA ENIM TAHUN 2018

2019 ◽  
Vol 9 (01) ◽  
pp. 44-48
Author(s):  
Shinta Maharani ◽  
Devy Dwi Putri
Keyword(s):  
Standard Deviation ◽  
Experimental Design ◽  
Average Concentration ◽  
A Value ◽  
Significant Difference ◽  
Before And After ◽  
Quasi Experimental ◽  
The Difference ◽  
The One ◽  
Mean Concentration

One of the tasks of the development of children aged 11-15 years is to think in a more abstract and logical way and more idealistic thinking. This ability to think will be disrupted if teenagers have difficulty concentrating during learning. Therefore we need a method that is fun and can make children relax in learning so that they can concentrate their concentration on ongoing learning. One method that can be used is the Murrotal Al-Qur'an therapy. The aim of the study was to determine whether there was any effect of murottal therapy on the concentration of students at Muara Enim 2 MTsN. This study used a quasi-experimental design with the design of the one group pretest posttest. The sample used was all students of class VIII.G at MTsN 2 Muara Enim. The results showed that the average concentration score of class VIII.G students before Murottal therapy was given was 10.84 with a standard deviation of 3.043. While the average concentration score of class VIII.G students after being given murottal therapy was 17.90 with a standard deviation of 1.233, so that the difference in mean concentration scores before and after murottal therapy was 7.06 with a standard deviation of 1.81. Wilcoxon signed ranks test obtained ρ value = 0,000, with a value of α = 0.05 (p <0.05), this shows that there is a significant difference between the concentration of students before and after being given murottal therapy. It is expected that the school can make a policy about the application of murottal therapy in increasing student concentration.

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