Infections and ABO Blood Groups in Burn Patients.

Blood ◽  
2005 ◽  
Vol 106 (11) ◽  
pp. 4179-4179
Author(s):  
Areta Kowal-Vern ◽  
Leonard I. Boral ◽  
Mariano G. Yogore ◽  
Harita Patel ◽  
Susan Brown
Keyword(s):  
Blood Group ◽  
Inhalation Injury ◽  
Blood Groups ◽  
Burn Patients ◽  
Abo Blood Groups ◽  
Chi Square ◽  
Significant Difference ◽  
Study Population ◽  
Tract Infections ◽  
Burn Patient

Abstract Background: Lack of isohemmaglutinins may predispose individuals to infection. The purpose of this study was to determine if there was a relationship between infections and burn patient blood groups. Methods: This was a retrospective review of burn patient data on infections and ABO blood groups between March 1999-May 2004. Chi-square and Mann-Whitney U with one-way ANOVA statistical analyses were performed. Results: There were 1615 burn admissions; 794 patients were typed for blood groups; 179 patients received blood transfusions. Of the study population, African-Americans constituted 59%, Hispanics 21%, Caucasians 16%, and others 4%. Although age (mean±se: 37±2 years), % TBSA (11±2%), and inhalation injury (15%) were similar in all groups, patients with B blood group had longer BICU stays compared to the O blood group, p<0.01. There was no statistically significant difference among the blood groups in the number of nosocomial wound infections, episodes of sepsis, bacteremia, urinary tract infections (UTIs) or pneumonia. The bacterial etiology was similar in all blood groups without any species preponderance. Transfused patients had a higher frequency of infections compared to those who were not transfused and significance was only reached in the comparison for UTIs, p=0.02. Conclusions: Our data shows that burn patients with B and AB blood groups did not have an increased frequency of infections compared to the patients with A and O blood groups. Burn patients were immunosuppressed as part of their injury. Those who received transfusions probably had a further perturbation of their immune system, since blood products cause immunosuppression. Other factors such as inhalation injury and %TBSA also predisposed burn patients to infection. Transfusions rather than blood groups were associated with an increased number of nosocomial UTIs in burn patients. Demographic Characteristics of the Burn Population by ABO Groups Blood Groups AB A B O mean ± s.e. Study Population # (%) 27 (3) 258 (32) 134 (17) 375 (47) Study African American (%) 4 29 21 46 Study Hispanic (%) 1 36 7 56 Study Caucasian (%) 3 37 14 46 BICU stay (days) 15±6 13±2 23±4 11±1 PRBC Transfusions (units) 7±2 9±2 13±3 8±1 UTI/Transfused # (%) 5 (100) 12 (92) 8 (89) 20 (60) UTI/Not Transfused # (%) 0 1 (8) 1 (11) 13 (40)

scholarly journals Association of ABO blood groups with presentation and outcomes of confirmed SARS CoV-2 infection: A prospective study in the largest COVID-19 dedicated hospital in Bangladesh

PLoS ONE ◽  
2021 ◽  
Vol 16 (4) ◽  
pp. e0249252
Author(s):  
Reaz Mahmud ◽  
Mohammad Aftab Rassel ◽  
Farhana Binte Monayem ◽  
S. K. Jakaria Been Sayeed ◽  
Md Shahidul Islam ◽  
...  
Keyword(s):  
Blood Group ◽  
Blood Groups ◽  
Abo Blood Groups ◽  
Duration Of Symptoms ◽  
Presenting Symptoms ◽  
Blood Group A ◽  
Group I ◽  
Significant Difference ◽  
Group A ◽  
Group Ii

Background Globally, studies have shown conflicting results regarding the association of blood groups with SARS CoV-2 infection. Objective To observe the association between ABO blood groups and the presentation and outcomes of confirmed COVID-19 cases. Design, setting, and participants This was a prospective cohort study of patients with mild-to-moderately severe COVID-19 infections who presented in the COVID-19 unit of Dhaka Medical College Hospital and were enrolled between 01 June and 25 August, 2020. Patients were followed up for at least 30 days after disease onset. We grouped participants with A-positive and A-negative blood groups into group I and participants with other blood groups into group II. Results The cohort included 438 patients; 52 patients were lost to follow-up, five died, and 381 completed the study. The prevalence of blood group A [144 (32.9%)] was significantly higher among COVID-19 patients than in the general population (p < 0.001). The presenting age [mean (SD)] of group I [42.1 (14.5)] was higher than that of group II [38.8 (12.4), p = 0.014]. Sex (p = 0.23) and co-morbidity (hypertension, p = 0.34; diabetes, p = 0.13) did not differ between the patients in groups I and II. No differences were observed regarding important presenting symptoms, including fever (p = 0.72), cough (p = 0.69), and respiratory distress (p = 0.09). There was no significant difference in the median duration of symptoms in the two group (12 days), and conversion to the next level of severity was observed in 26 (20.6%) and 36 patients (13.8%) in group I and II, respectively. However, persistent positivity of RT-PCR at 14 days of initial positivity was more frequent among the patients in group I [24 (19%)] than among those in group II [29 (11.1%)]. Conclusions The prevalence of blood group A was higher among COVID-19 patients. Although ABO blood groups were not associated with the presentation or recovery period of COVID-19, patients with blood group A had delayed seroconversion.

Anti-Von Willebrand Factor Antibody Is Responsible for Lower Levels of Plasma vWF in Blood Group O Individuals.

Blood ◽  
2004 ◽  
Vol 104 (11) ◽  
pp. 254-254 ◽  
Author(s):  
Letian Dai ◽  
Shawn Cotton ◽  
Alistair Macartney ◽  
Geoffrey Savidge ◽  
Anwar Alhaq
Keyword(s):  
Blood Group ◽  
Blood Groups ◽  
Bleeding Tendency ◽  
Plasma Samples ◽  
Abo Blood Groups ◽  
Acquired Von Willebrand Syndrome ◽  
Significant Difference ◽  
Group A ◽  
Group B ◽  
Von Willebrand

Abstract Plasma levels of vWF are known to be influenced by ABO blood groups, although the mechanism remains unresolved. Group O individuals have a significantly lower level of plasma vWF than those with group A, B or AB. This relative lower level of plasma vWF may result in a bleeding tendency and a shorter half-life of infused factor VIII in group O individuals. The formation of immune complexes between vWF and autoantibodies has been shown to accelerate vWF clearance from plasma in acquired von Willebrand syndrome. However, so far no evidence has been presented that the presence of autoantibodies against vWF is involved in lowering plasma level of vWF in group O individuals. In the present study, plasma samples were obtained from 199 healthy blood donors of blood group O (50), group A (50), group B (49), and group AB (50). A time-resolved fluorescence immunoassay (TRFIA) was developed to detect anti-vWF IgG in plasma samples. Briefly, 100 μl of diluted plasma was loaded on to duplicated vWF-coated and untreated control wells of a microplate. After incubation and washing, 100 μl of Europium-labeled anti-human IgG conjugate (1:500 dilution) was added to the plate to detect vWF IgG. The time-delayed fluorescence was then measured with a Victor microplate reader (PerkinElmer, Turku, Finland). The fluorescence counts of the control wells were subtracted from those of the vWF-coated wells. The results show that anti-vWF IgG was present in all four blood groups (Table 1). Of these blood groups, group O had the highest anti-vWF IgG level with 9.8 x 105 fluorescence counts, which was 2.7- to 3.5-fold higher than that of group A, B or AB. There was a significant difference in the anti-vWF IgG levels between group O and the rest of group A, B or AB. Quantitative analysis of plasma vWF by ELISA showed that the concentration of plasma vWF of group O was 29 to 35% lower than that of group A, B or AB (Table 1). These results suggest that TRFIA is a sensitive assay for detection of anti-vWF IgG in plasma samples, and the presence of the high level of anti-vWF Ig G in group O individuals may be responsible for lowing plasma vWF by acceleration of vWF clearance. Anti-VWF IgG levels and vWF concentrations in diffeent ABO blood groups Group O (n=50) Group A (n=50) Group B (n=49) Group AB (n=50) Data are presented as a mean ± SD. *P<0.01 compared with group A, B or AB. +P<0.01 compared with group A,B or AB. Anti-vWF IgG (x 105 Fluorescence counts) 9.8 ± 6.9* 2.8 ± 2.8 3.1 ± 3.0 3.6 ± 3.5 Concentration of vWF (% of normal controls) 116 ± 42+ 165 ± 46 165 ± 42 179 ± 49

scholarly journals Frequency and correlation of lip prints, fingerprints and ABO blood groups in population of Sriganganagar District, Rajasthan

2018 ◽  
Vol 46 (2) ◽  
pp. 105
Author(s):  
Harpreet Sandhu ◽  
Pradhuman Verma ◽  
Sarfaraz Padda ◽  
Seetharamaiha Sunder Raj
Keyword(s):  
Blood Group ◽  
Blood Groups ◽  
Personal Identification ◽  
P Value ◽  
Type I ◽  
Abo Blood Groups ◽  
Chi Square ◽  
Team Members ◽  
Kappa Test ◽  
Type V

<div class="WordSection1"><p><strong>Objective. </strong>To investigate the frequency and uniqueness of different lip print patterns, fingerprint patterns in relation to gender and ABO Rh blood groups among a semi-urban population of Sriganganagar, Rajasthan. <strong>Materials and methods. </strong>The study was conducted on 1200 healthy volunteers aged 18-30 years. The cheiloscopic and der- matographic data of each subject were obtained and were analysed according to the Suzuki and Tsuchihashi and Henry systems of classification, respectively. Two forensic experts analyzed the patterns independently. The ABO Rh blood group was also recorded for each subject. The Chi square statistical analysis was done and tests were considered significant when p value &lt;0.001 and Cohen kappa test was applied to analyze inter-observer reliability. <strong>Results. </strong>The B+ blood group was noted as most common in both genders while least common were A− among males and AB− in females. Type II lip pattern was most predominant while the least common was Type I’ in males and Type I’ and Type V in females. The UL fingerprint pattern was the most common, while RL was least noted in both genders. All the fingerprint patterns showed correlation with different lip print patterns. A correlation was found between different blood groups and lip print patterns except Type I (vertical) lip pattern. A positive correlation was observed between all the blood groups and fingerprint patterns, except for RL pattern. <strong>Conclusion. </strong>There is an association between lip print patterns, fingerprint patterns and ABO blood groups in both the genders. Thus, correlating the uniqueness of these physical evidenc- es sometimes helps the forensic team members in accurate personal identification or it can at least narrow the search for an individual where there are no possible data referring to the identity of the subject.</p></div>

scholarly journals The Impact of ABO Blood Group on Clinical Outcomes and Susceptibility in COVID-19: A Retrospective Population Study of 3305 Patients

Blood ◽  
2020 ◽  
Vol 136 (Supplement 1) ◽  
pp. 32-33
Author(s):  
Waleed Alduaij ◽  
Sarah Al-Youha ◽  
Ahmad Al-Serri ◽  
Sulaiman Almazeedi ◽  
Mohannad Al-Haddad ◽  
...  
Keyword(s):  
General Population ◽  
Clinical Outcomes ◽  
Blood Group ◽  
Blood Groups ◽  
National Database ◽  
Abo Blood Group ◽  
Abo Blood Groups ◽  
Susceptibility To Infection ◽  
Significant Difference ◽  
Group A

Background: Factors determining inherent susceptibility to infection with the novel severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and the risk of severe outcomes in infected individuals remain poorly understood. Landsteiner ABO blood groups have been linked to host susceptibility to various infections through the interaction of the carbohydrate moieties defining ABO antigens with micro-organisms and the immune system. Previous studies of the original SARS coronavirus (SARS-CoV-1) demonstrated a decreased susceptibility to infection in group O individuals (Cheng et al. JAMA 2005; 293:1450-1) and the ability of plasma-derived anti-A antibodies to block the interaction between viral spike protein and human angiotensin-converting enzyme 2 receptor in vitro (Guillon et al. Glycobiology 2008; 18:1085-93). A recent genome-wide association study of patients with respiratory failure complicating coronavirus disease 2019 (COVID-19) suggested a higher risk of severe disease in group A, and a protective effect in group O (Ellinghaus et al. NEJM 2020 DOI:10.1056/NEJMoa2020283). Since the inception of the COVID-19 pandemic, a broad testing strategy was implemented in Kuwait and all individuals testing positive for SARS-CoV-2 were admitted to a single facility, including asymptomatic individuals. Here we examined the clinical outcomes of this cohort with respect to ABO blood group and compared its blood group distribution to that of the general population. Methods: All patients testing positive for SARS-CoV-2 by polymerase chain reaction assay of a nasopharyngeal swab specimen that were admitted to Jaber Hospital between February 24th to May 27th 2020 were included in the study. Relevant demographic and clinical data were extracted from hospital records. An anonymized summary of the distribution of blood types of the entire population of Kuwait was obtained from a national database and used as a control group. Clinical outcomes were in accordance with international consensus definitions. Appropriate statistical tests were used for bivariate analysis. Multivariate logistic regression was performed to determine relationships between variables of interest and outcome. Results: Of 3305 SARS-CoV-2 positive patients 37.1%, 25.5%, 28.9% and 8.5% were group O, A, B and AB respectively. 69.2% were male and 30.8% were female. Median age was 42 years. 48.1% were Kuwaiti citizens and 51.9% were non-Kuwaiti. Commonest comorbidities were hypertension (21.5%) and diabetes (20.1%). 17.4% were obese. 37.2% were asymptomatic on admission. There was no significant difference in baseline characteristics among the blood groups. Univariate analysis of clinical outcomes revealed no significant differences in need for oxygen support, admission to intensive care, intubation or death among the blood groups. However, rates of any adverse event and pneumonia differed significantly (Table 1). Multivariable analysis adjusted for age, sex, obesity and comorbidities showed that group A had higher odds of developing pneumonia compared to the other blood groups combined (adjusted odds ratio 1.32, 95% confidence interval 1.02-1.72, p&lt;0.0363). We found no relationship between pneumonia and other blood groups. Compared to the general population, the COVID-19 cohort had a lower frequency of group O, equivalent frequency of group A and higher frequency of groups B and AB (Table 2). This trend was independent of nationality (Kuwaiti versus non-Kuwaiti). Incorporation of Rh (D) status did not impact the trend observed with ABO blood groups. Finally, no significant difference in Rh (D) status was found between the COVID-19 and general populations (Rh positive 93.4% versus 93.6% respectively, p=0.99) Conclusion: In a large, unselected patient population, no association between blood group and severe clinical outcomes in COVID-19 was found. Consistent with reports in other populations, we found a lower prevalence of blood group O in SARS-CoV-2 positive individuals and higher prevalence of blood group B and AB implicating a potential role of ABO blood group in susceptibility to infection. No association between SARS-CoV-2 infection with blood group A or Rh (D) group was found. Further examination of the mechanistic link between ABO antigens, antibodies and SARS-CoV-2, and its implications on controlling the current pandemic is warranted. Disclosures No relevant conflicts of interest to declare.

The Relation between the Blood Groups, Rhesus Factor, and Breast Cancer in the Holy Karbala Governorate

2020 ◽  
pp. 31-33
Keyword(s):  
Breast Cancer ◽  
Blood Group ◽  
Type A ◽  
Blood Groups ◽  
Abo Blood Groups ◽  
Group Type ◽  
Rhesus Factor ◽  
Significant Difference ◽  
Healthy Control ◽  
Blood Group Type

The distribution ABO blood groups among patients with breast cancer were as follow: blood group type O (40.8%), blood group type A (25.0%), B (23.7%), and AB (10.4%), for the donor’s healthy control, ABO blood groups percentages were as follow: type O (39.9%) type A (28.1%), type B (22.0%), and type AB (9.9%). There is no significant association between blood types ABO and the breast cancer. (P > 0.05) Rh factor has a significant difference between patients with breast cancer and healthy control (P=0.002). There were significant differences in age categories among patients with breast cancer and controls. (p= 0.000) .

Variation of Both Blood Group H and ABO Glycans Is Associated with VWF Levels

Blood ◽  
2012 ◽  
Vol 120 (21) ◽  
pp. 3314-3314
Author(s):  
Jill M. Johnsen ◽  
Kerry W Lannert ◽  
Ermias Yohannes ◽  
Xiomara Castillo ◽  
Karl C. Desch
Keyword(s):  
Blood Group ◽  
Blood Groups ◽  
Buffy Coat ◽  
Abo Blood Group ◽  
Abo Blood Groups ◽  
Significant Difference ◽  
Post Hoc ◽  
Von Willebrand ◽  
The Impact ◽  
One Way Anova

Abstract Abstract 3314 ABO(H) is a carbohydrate blood group system primarily expressed on red cells, blood vessels, and mucosal surfaces. ABO blood group is known to influence von Willebrand Factor (VWF) levels, with low VWF associated with blood group O and increased diagnosis of von Willebrand Disease. Conversely, non-O blood group is associated with high VWF levels, and both non-O blood group and high VWF are associated with thrombotic vascular disease. We sought to characterize VWF levels relative to ABH glycan phenotypes in 1129 individuals from a healthy sibling cohort, the Genes and Blood Clotting Cohort (GABC). VWF:Ag levels were determined by AlphaLISA (Perkin Elmer) in platelet poor plasma. ABH forensic techniques were adapted to samples of RBC-rich, frozen buffy coat in the study repository. In brief, buffy coat fractions were diluted in TBS, applied to nitrocellulose, and A and B glycans detected using murine monoclonal anti-A (Immucor) or murine monoclonal anti-B (Immucor) followed by and streptavidin-conjugated donkey anti-mouse IgG HRP (Jackson ImmunoResearch). A biotinylated Ulex europaeus agglutinin (UEA lectin, Vector Labs) was used to detect H, followed by streptavidin-HRP. Blots were imaged using ImageQuant (GE) and scored semi-quantitatively for glycan density by two blinded independent observers using reference buffy coats from normal blood donors. ABO blood group frequencies were similar to that of the U.S. population (O=40%, A=42%, B=12%, AB=6%). Also consistent with previous reports, VWF:Ag levels varied significantly between ABO blood groups (O<A<B=AB, see Table 1). Within blood group A, we observed variation in A glycan density (scored 1+ to 3+). Lower A glycan density (similar to the A2 reference) correlated significantly (p<0.01) with lower VWF:Ag levels (see Table 1), and also appeared to have higher detectable H antigen. We also observed wide variation in H glycan density (scored 1+ to 5+). Overall, detection of A and B glycan density patterns were inversely related to H glycan, consistent with glycosylation of H by the ABO enzyme. Interestingly, higher H density correlated significantly (p<0.01) with lower VWF:Ag levels, even within blood group O (see Table 2). In summary, ABH glycan variation may impact VWF in a more complex fashion than previously suspected. Although these data are limited to semi-quantitative analyses by the heterogeneous nature of RBC-rich buffy coat, our findings are consistent with expectations for major ABO blood group frequencies and show that variation of RBC rich-buffy coat ABH glycan density within and between ABO blood groups correlates with VWF:Ag level. This work also suggests a previously unsuspected association between VWF and variation in H antigen, which we hypothesize may be due to variation in the FUT genes or other loci affecting H glcosylation patterns. Further work to characterize the complexity of the ABH carbohydrate system and its genetic determinants is warranted to better understand the impact of ABH subtypes on VWF and vascular phenotypes. Table 1. ABO Blood Groups, Buffy Coat A Glycan Density, and VWF:Ag Level Number of Subjects ABO Blood Group VWF:Ag (+/−1SD) VWF Difference (Ovs.Avs.Bvs.AB)* Difference from Group O* 454 O 90+/−35 473 A 119+/−45 p<0.01 p<0.01 138 B 130+/−50 p<0.01 p<0.01 64 AB 128+/−52 NS p<0.01 Number of Subjects A Glycan Density Avg H Glycan Density VWF:Ag (+/−1SD) VWF Difference (A1+vs.2+vs.3+)* Difference from A 1+* 68 1+ 3.5 98+/−40 195 2+ 2.4 123+/−44 p<0.01 p<0.01 210 3+ 2.0 123+/−45 NS p<0.01 * Each section above: One-way ANOVA; post-hoc Tukey's Least Significant Difference. Table 2. Buffy Coat H Glycan Density and VWF:Ag Level H Glycan Density in All Subjects Number of Subjects H Glycan Density VWF:Ag (+/−1SD) VWF Difference (H1vs.2vs.3vs.4vs.5)* Difference from H 1+* 52 1+ 135+/−46 257 2+ 130+/−53 NS NS 260 3+ 117+/−44 p<0.01 p<0.01 307 4+ 99+/−37 p<0.01 p<0.01 252 5+ 88+/−32 p<0.05 p<0.01 H Glycan Density in Blood Group O Subjects Number of Subjects H Glycan Density** VWF:Ag (+/−1SD) VWF Difference (H3+vs.4+vs.5+)* Difference from H 3+* 29 3+ 115+/−57 207 4+ 92+/−33 p<0.01 p<0.01 214 5+ 85+/−30 NS p<0.01 * One-way ANOVA; post-hoc: Tukey's Least Significant Difference. ** No blood group O individuals scored <3+ H glycan density. Disclosures: No relevant conflicts of interest to declare.

scholarly journals Association Between ABO Blood Groups And Myocardial Infarction In Jodhpur City of India

2012 ◽  
Vol 7 (1) ◽  
pp. 13-17
Author(s):  
Priyanka Garg ◽  
Jayant Kumar ◽  
Raghuveer Choudhary ◽  
VK Chawla
Keyword(s):  
Myocardial Infarction ◽  
Blood Group ◽  
Local Population ◽  
Cross Sectional Study ◽  
Blood Groups ◽  
Abo Blood Group ◽  
Abo Blood Groups ◽  
Chi Square ◽  
Cross Sectional ◽  
Group B

Background: Many reports have appeared in recent years showing an association between blood  groups and Myocardial Infarction. Clinical studies have shown a significant association between MI  and blood group B.Objective: To investigate correlation of ABO blood groups with risk of MI.Methods: The present cross sectional study analyzed ABO blood group among total 400 subjects of  any age from the local population of Jodhpur city from July to December 2011.Among them 200  subjects were normal health (135 male and 65 female) students of Dr. S.N. Medical College, Jodhpur  and another 200 (135 male, 65 female) were MI patients admitted in the CCU of Mathura Das  Memorial (MDM) Hospital, Jodhpur. ABO blood group of all subjects were determined by slide  agglutination method. Risk of MI was expressed by risk ratio. Data were analyzed by one sample chi  square test.Results: The results obtained in this study showed that the prevalence of MI in blood  group B is significantly higher than in all other ABO blood groups.Conclusion: The results may  conclude that there is a significant association between MI and blood group B. So this study reveals  MI risk is associated with the blood group B. DOI: http://dx.doi.org/10.3329/jbsp.v7i1.11154 J Bangladesh Soc Physiol. 2012, June; 7(1): 13-17

scholarly journals ABO Blood Group System and the Association with Cardiovascular Risk Factors between Men and Women with Cardiovascular Diseases—A Comparative Study

2020 ◽  
Vol 5 (02) ◽  
pp. 111-116
Author(s):  
Rachana Katna ◽  
Ch Srinivasa Rao ◽  
Aswin Kumar M. ◽  
Farheen Fatima ◽  
Madhuri Taranikanti
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Blood Group ◽  
Ldl Cholesterol ◽  
Density Lipoprotein ◽  
Blood Groups ◽  
Abo Blood Group ◽  
Abo Blood Groups ◽  
Significant Difference

Abstract Objectives The present study was designed to explore the relation between ABO blood group and cardiovascular risk factors in the patients attending tertiary care hospital in South India. Materials and Methods One hundred nine patients, each male and female with different cardiovascular diseases, were included in the study and their ABO blood groups were analyzed with the cardiovascular risk factors. A detailed history was taken from all the patients regarding cardiovascular risk factors like high blood pressure, diabetes, and lipidemic. Total cholesterol, high density lipoprotein (HDL) cholesterol, low density lipoprotein (LDL) cholesterol, and serum triglycerides were determined for assessing lipidemia. Blood grouping was done using standard tube technique. Red cell and serum grouping was performed and results documented. Association between ABO blood groups and cardiovascular risk factors was done using chi-square test and Spearman’s correlation. Results The distribution of ABO blood groups shows that blood group O (41.28%) was more common in patients followed by group B (29.36%), group A (19.27%), and group AB (10.09%). One-hundred six cases (97.2%) were Rh D positive. A statistically significant difference was observed between gender and total cholesterol, LDL cholesterol and BMI with p value <0.05. In the study population, distribution of major cardiovascular risk factors, especially diabetes mellitus and dyslipidaemia, with ABO blood groups shows that there was no significant difference observed between blood groups and these cardiovascular risk factors. However, statistical significance was there between blood group O and hypertension (p = 0.03). Conclusion There was no significant difference between the blood groups and the major cardiovascular risk factors were diabetes and lipids, but there was an association between blood group O and hypertension.

scholarly journals Influence of ABO and Rhesus Blood Group on Blood Pressure and Hypertension in Bayelsa State

2021 ◽  
pp. 33-40
Author(s):  
S. O. Ojeka ◽  
D. V. Dapper ◽  
A. M. Egbejimi
Keyword(s):  
Blood Pressure ◽  
Blood Group ◽  
Study Design ◽  
Teaching Hospital ◽  
Niger Delta ◽  
Blood Groups ◽  
University Teaching ◽  
Abo Blood Groups ◽  
Cross Sectional ◽  
Significant Difference

Aim: This present study was carried out to ascertain the influences of ABO and Rhesus blood groups on blood pressure and hypertension among normotensive and hypertensive patients attending cardiologic clinic in Niger delta University Teaching Hospital, Okolobiri in Yenagoa Local Government Area of Bayelsa State Nigeria. Study Design: Cross sectional study design was adopted. Place and Duration of Study: The study was carried out in the Cardiology Clinics in the Niger Delta University Teaching Hospital (NDUTH), Okolobiri, Bayelsa State, from February 2020 to November 2020. Methodology: This study was carried out on 800 participants, consisting of 400 each of apparently healthy Normotensive and Hypertensive individuals. The blood pressures were determined using palpatory and auscultatory (stethoscope and sphygmomanometer) method in both control and hypertensive groups and their ABO and Rhesus blood groups were determined using the slide haemagglutination technique. Statistical analysis was done using SPSS statistical software to perform Chi-square test. Results: The frequency of the various blood groups was A-20.0%, B-16.8%, AB-13.3% and O-50.0% for the normotensive individuals and A-12.0%, B-15.5%, AB-17.8% and O-54.8%, for the hypertensive individuals. The frequency of ABO blood groups in both the normotensive and hypertensive group was therefore found to be O>B>A>AB. The prevalence of blood group O and rhesus O-ve was found to be  associated with elevated blood pressure and the development of hypertension while prevalence of blood group AB was found to be lowest in the same group, but was not significant statistically (p>0.05). There was no significant difference between systolic and diastolic blood pressure of different blood groups. Conclusion: Blood group O was found to be the most common blood group in our study. Blood group O- was also found to be more prone to hypertension. However, there was no statistically significant association between ABO blood groups and Hypertension.

The association between ABO blood groups and TASC II classification in patients with peripheral artery disease

Vascular ◽  
2022 ◽  
pp. 170853812110687
Author(s):  
Zeki Yüksel Günaydın ◽  
Emre Yılmaz
Keyword(s):  
Blood Group ◽  
Peripheral Artery Disease ◽  
Multiple Logistic Regression Analysis ◽  
Blood Groups ◽  
Abo Blood Groups ◽  
Peripheral Artery ◽  
Entire Study ◽  
Study Results ◽  
Study Population ◽  
Artery Disease

Objective The aim of this study was to investigate the association between blood groups and severity of peripheral artery disease (PAD) using TASC II classification. Methods The patients who were diagnosed with PAD were retrospectively analyzed. The patients with 50% or more stenosis in the aorto-iliac or femoro-popliteal region detected by conventional or CT angiography were included in the study. These patients were divided into TASC II A, B, C, and D groups considering the severity of PAD. All patients’ blood groups were recorded and compared between TASC II groups. Results While 38% of the study population was O blood group, 61% were non-O group. On the other hand, 90% of the entire study population were RH positive and 10% were RH negative. Non-O blood ratio was found to be significantly higher in patients with higher TASC II groups. (TASC IIA 51.6% vs. TASC IIB 57.9% vs. TASC IIC 61.3% vs. TASC IID 76.6%, p< .001) However, the frequencies of Rh types were similar in all groups. Multiple logistic regression analysis was applied for determining the predictors of severity and complexity of PAD (TASC II C and TASC II D lesions) Conclusions Our study results revealed a clear association between ABO blood groups and severity of peripheral arterial disease. Non-O blood group was found to be the independent predictor of severe and complex PAD.

Sign in / Sign up

Export Citation Format

Share Document