Comparison of fasting blood sugar between patients with schizophrenia and control group

Objective: This research has been carried out to evaluate the levels of [25(OH)D3] as well as the correlation between the deficiency levels with the risk of experiencing T2DM in sample of Iraqi population. Methods: The levels regarding the 25-hydroxy vitamin D3 and the fasting blood sugar (FBG) have been estimated in group of 58 T2DM patients and 31 control subjects of age between (25 - 65 year). The 25-hydroxy vitamin D3 has been estimated via ELISA and fasting blood sugar (FBG) was measured spectrophotometrically. Results: The levels of 25-hydroxy vitamin D3 have been considerably lower in individuals experiencing T2DM (9.465 ± 3.567 ng/ml) than in the control group (14.146 ± 11.045 ng/ml), (P = 0.02) whereas FBG levels were considerably higher in patients experiencing T2DM (218 ± 66 mg/dl) widespread in comparison to control group (89.8 ± 9 mg/dl), (P = 0.009). The levels related to the 25-hydroxy vitamin D3 are inversely related to FBG in both diabetic and control group (P = 0.01, r2 = 0.1), (P < 0.01, r2 = 0.2) respectively. VDD is considered to be related to the hazard of experiencing T2DM; also it is highly prevalent in subjects of Iraqi nationality. Conclusion: VDD is associated to the risk of experiencing T2DM. hypovitaminosis D is very prevalent among the study participants and its percent was higher in female and have a therapeutic implications as cautious supplementation of vitamin D could enhance glycemic control in T2DM.

Download Full-text

Effectiveness of Gita Gymnastics on Blood Sugar Level Among Elderly With Diabetes Mellitus in Kediri

Healthy-Mu Journal ◽

10.35747/hmj.v4i1.539 ◽

2020 ◽

Vol 4 (1) ◽

pp. 60

Author(s):

Anindini Winda Amalia ◽

Paramita Ratna Gayatri ◽

Hartati Tuna

Keyword(s):

Diabetes Mellitus ◽

Blood Sugar ◽

The Elderly ◽

Fasting Blood Sugar ◽

Control Group ◽

Mean Deviation ◽

Significant Difference ◽

Group 10 ◽

Sugar Levels ◽

And Control

The Elderly has a high risk of degenerative diseases. Diabetes Mellitus is a degenerative disease that occurred in the elderly. Excercise regularly can reduce blood sugar levels in the elderly. GITA gymnastic is a mild exercise that can be applied and not burdensome if done routinely by elderly. The purpose of this study was to determine the effect of GITA gymnastic on blood sugar levels in the elderly with diabetes mellitus. This research is an experimental design of the field with pre-post group design. Respondents are elderly with diabetes mellitus in Clinic Bandar Lor Kediri. Respondent 20 people, divided into two groups, gymnastic group 10 people and control group 10 people. In gymnastic group is given training of GITA gymnastic for 8 weeks, 3 times a week, with a duration of 30 minutes each session. The control group did not have treatment. The result of this study indicates the post-test of fasting blood sugar levels in the gymnastic group is significantly lower than the pre-test of fasting blood sugar levels (p= 0.003). In the independent T test, there was a significant difference in the mean deviation of fasting blood sugar levels in the gymnastic group and control group (p=0,001). GITA gymnastic for eight weeks is effective in reducing blood sugar levels among the elderly with diabetes mellitus.

Download Full-text

Biochemical Profile and Assessment of risk factors for Patients Diagnosed with Myocardial Infarction in Al-Ramadi City, Iraq

Kurdistan Journal of Applied Research ◽

10.24017/science.2017.2.10 ◽

2017 ◽

Vol 2 (2) ◽

pp. 78-83

Author(s):

Marwan Mahmood Saleh

Keyword(s):

Risk Factors ◽

Myocardial Infarction ◽

Blood Sugar ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Fasting Blood Sugar ◽

Total Serum ◽

Control Group ◽

Enzymatic Markers ◽

And Control

Myocardial infarction (MI) continues to be a major cause of mortality and also death at early ages all over the world. This study is undertaken to evaluate the effect of MI on the levels of lipid profile, two enzymatic markers, fasting blood sugar (FBS), urea, creatinine and total serum bilirubin (TSB), rather than to assess the risk factors which lead to MI and its relation to these variables. The sample of the study consisted of (50) patients admitted to the Cardiac Care Unit in Al-Ramadi General hospital. MI patients had significantly (P≤0.05) higher levels of triglyceride (TG) (201.4 mg/dl) as compared with the controls (142.8 mg/dl), while high density lipoprotein (HDL) significantly (P≤0.05) decreased in patients (42.24 mg/dl) compared with control group (58.7mg/dl). Total cholesterol (TC) (183.6 mg/dl) and low density lipoprotein (LDL) (109.3mg/dl) were not affected significantly (P≤0.05) in MI group when compared with control group with the average of (172.2 mg/dl), (116 mg/dl) respectively. Aspartate aminotransferase (AST) increased significantly (P≤0.05) in patients (61.38 IU/L) compared to the control group (23.5 IU/L) , while there was no significant (P≤0.05) difference in alkaline phosphatase (ALP) between MI and control group. Levels of fasting blood sugar (FBS) in the serum of MI group (206 mg/dl) increased significantly (P≤0.05) comparing with the control group (122.1 mg/dl). This study showed increase in urea (55.6 mg/dl) and creatinine (1.26 mg/dl) levels in the MI group contrast with the control group which its mean was (29.8 mg/dl), ( 0.85 mg/dl) respectively. There was no difference in the level of TSB. Findings of this study, stating differences in levels of some biochemical parameters can use as a biomarker of myocardial infarction. There is an increase in the incidence of myocardial infarction and some differences in the level of parameters in the presence of one or more major risk factors.

Download Full-text

Detection of Anti-Helicopacter pylori IgG Antibody, Anti-GAD antibody, Anti-Beta islets cell in a sample of serum with type-2 Diabetes mellitus patients

Baghdad Science Journal ◽

10.21123/bsj.10.4.1157-1161 ◽

2013 ◽

Vol 10 (4) ◽

pp. 1157-1161

Author(s):

Baghdad Science Journal

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Type 2 Diabetes Mellitus ◽

Blood Sugar ◽

Fasting Blood Sugar ◽

Control Group ◽

Acid Decarboxylase ◽

Igg Antibody ◽

H Pylori

We have investigated twenty five patients with type-2 diabetes mellitus aged (35-60) years and fifteen healthy persons as control group to detect Anti-Helicobacter pylori IgG antibody. All studied groups were carried out to measure fasting blood sugar, anti- Glutamic acid decarboxylase (GAD), anti-? islets cells antibody by IFAT, Anti-H. pylori IgG antibody by ELISA technique. There was significant elevation in the concentration of fasting blood sugar than in control group (P < 0.05), the patients had negative results for anti-GAD antibody and anti- ? islets cells antibody, there were significant differences (P < 0.05) of anti-H. pylori IgG antibody in 28 % of patients had type-2 diabetes than control group. This lead to suggestion that type -2 diabetes mellitus patients are more susceptible to H. pylori .

Download Full-text

Effects Of Music Therapy On Clinical And Biochemical Parameters Of Metabolic Syndrome

Journal of Bangladesh Society of Physiologist ◽

10.3329/jbsp.v6i2.9760 ◽

1970 ◽

Vol 6 (2) ◽

pp. 108-115 ◽

Cited By ~ 2

Author(s):

Madhuri Sharma ◽

Dr Rajnee ◽

Kamlesh Chandra Mathur

Keyword(s):

Blood Pressure ◽

Metabolic Syndrome ◽

Music Therapy ◽

Blood Sugar ◽

Biochemical Parameters ◽

Conventional Treatment ◽

Fasting Blood Sugar ◽

Control Group ◽

Study Group ◽

Waist Hip Ratio

Background: Music therapy is a new approach being used for the management of metabolic abnormalities and stress related illness. Objective: To study the effect of Music therapy on various clinical and biochemical parameters of Metabolic Syndrome. Methods: This cross sectional study was carried out on 100 patients of metabolic syndrome selected randomly. These patients were divided into two equal groups after age, sex adjustment. In control group (group I) 50 patients underwent the conventional treatment. 50 patients in study group were treated with supervised music protocol along with conventional treatment. The Body Mass Index, ;Waist-Hip ratio, Blood pressure, Fasting blood sugar were monitored weekly while HbA1c and lipid profile were determined at the baseline and after three months of exposure to music therapy. Statistical analysis was performed by employing student t- test. Results: In the study group there was a significant decrease in BMI (27.18±5.02 to 25.44±3.49 kg/m2, p<0.05), waist hip ratio (0.95±0.05 to 0.93±0.05 cm, p<0.05), Fasting blood sugar (196.00±47.80mg/ dl to152.00±16.19mg/dl , p<0.001), HbA1c (8.41±1.31% to 7.08±0.78 % p<0.001), Systolic Blood Pressure (151.00±12.10 to 136±9.04 mmHg p<0.001), Diastolic Blood Pressure (94±4.80 to 86.44±3.16 mmHg, p<0.01), Mean serum cholesterol (257.80±18.92 to 229.12±17.82mg/dl, p<0.001) and triglycerides (180.86±14.04 to 136.50±8.92mg/dl, p<0.001), LDL (167.97±14.40 to 140.20±15.41mg/dl, p<0.001), and VLDL (33.60±2.88 to 28.04±3.08mg/dl, p<0.001) and increase in HDL (33.32±3.38 to 39.71±3.41mg/dl, p<0.001), when compared with those of control group not receiving the music therapy along with the conventional treatment. Conclusion: The promising outcomes of Music therapy showed that it may be considered as a useful adjunct to conventional treatment in management of the metabolic syndrome. This study advocates music therapy to establish it from a general well being concepts to a neuroscience guided model. DOI: http://dx.doi.org/10.3329/jbsp.v6i2.9760 JBSP 2011 6(2): 108-115

Download Full-text

Diabetes mellitus patients’ fasting blood sugar levels and quality of life following brief pharmacist counseling with reminders and motivational messages

International Journal of Basic & Clinical Pharmacology ◽

10.18203/2319-2003.ijbcp20214885 ◽

2021 ◽

Vol 11 (1) ◽

pp. 13

Author(s):

Okta Muthia Sari ◽

Ginanjar Zukhruf Saputri ◽

Akrom .

Keyword(s):

Quality Of Life ◽

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Blood Sugar ◽

Short Form ◽

Fasting Blood Sugar ◽

Control Group ◽

Motivational Messages

Background: For chronic disease patients, pharmacist counselling with motivating reminder messages has been developed throughout time to promote the success of patient treatment. Diabetes mellitus is a long-term condition. Blood sugar control and an improved quality of life are therapeutic goals in the treatment of diabetes mellitus. The objective of this study was to determine whether changes in fasting blood sugar and quality of life occurred in individuals with diabetes mellitus who received pharmacist counselling coupled by motivating reminder messages.Methods: This quasi-experimental study used a pre-test-post-test design with control and intervention groups. Data on patients with type 2 diabetes were obtained prospectively at Jetis 1 primary health care in Bantul, Yogyakarta, Indonesia. Seventy-two respondents who met the inclusion criteria were separated into two groups: the control group (36 participants) and the intervention group (36 participants). The patients’ quality of life was assessed using the 36-item Short Form (SF-36) questionnaire.Results: Following pharmacist counselling coupled by motivating reminder messages, patients’ mean fasting blood sugar reduced significantly (∆ 34.85±63.36), while their mean quality of life score increased considerably (∆ 13.73±9.22).Conclusions: Pharmacist counselling combined with motivating reminder messages can help patients with type 2 diabetes lower their fasting blood sugar and enhance their quality of life. The provision of pharmacist counselling followed by brief reminders and motivational messages may be considered to improve type 2 diabetes patient management.

Download Full-text

Gestational Diabetes and Dietary Management with Split Meal Technique

Indian Journal of Pure & Applied Biosciences ◽

10.18782/2582-2845.8687 ◽

2021 ◽

Vol 9 (3) ◽

pp. 23-26

Author(s):

V. Lakshmi Prasanna ◽

Keyword(s):

Gestational Diabetes ◽

Blood Sugar ◽

Control Group ◽

Dietary Management ◽

Diet Survey ◽

Group Control Group ◽

And Control ◽

Biochemical Assessment ◽

Urine Sugar ◽

Experimental Group

Gestational diabetes and dietary management with split meal technique was studied with 90 sample which were collected through purposive sampling. Among 90 GDM patients were categorized into 2 equal groups I.e, Experimental group and control group. Control group consists of (n=45) and Experimental group also consists of (n=45). Anthropometric measurements, Biochemical assessment, and Diet survey were taken as parameters. Positive results were obtained in Experimental group. Significant decrease observed in weight, BMI, blood sugar and urine sugar in Split meal technique group. The results were decreased (from160.11 to 133.36 mg/dl in fasting blood sugar, 2.25 - 0.35 mg/dl urine sugar, 67.58- 64.11 kg in body weight).

Download Full-text

A study on the status of serum High Sensitive C - Reactive Protein and Fasting Blood Sugar in Patients with Hyperlipidemia attending a Super Specialty Teaching Hospital in North Kerala

International Journal of Research in Pharmaceutical Sciences ◽

10.26452/ijrps.v11i4.3677 ◽

2020 ◽

Vol 11 (4) ◽

pp. 6908-6912

Author(s):

Mohammed Muneersha T K ◽

Saravanakumar R T ◽

Revikumar K G ◽

Fathima Habeeba T E ◽

Jobin Louis ◽

...

Keyword(s):

Lipid Profile ◽

Blood Sugar ◽

Teaching Hospital ◽

Blood Sugar Level ◽

Fasting Blood Sugar ◽

Control Group ◽

Newly Diagnosed ◽

Significant Difference ◽

The Status ◽

Hs Crp

This study was aimed to analyses the serum Hs-CRP level and fasting Blood Sugar level in patients with Hyperlipidemia in a Super Specialty Teaching Hospital in north Kerala. This was a hospital-based prospective observational study which was conducted to study the status of Hs-CRP and Fasting Blood sugar level on lipid profile status of newly diagnosed Hyperlipidemia patients which was compared with Normal Lipid Profile people. Healthy subjects were recruited as a control group and newly Diagnosed Hyperlipidemia patients were recruited as Test group. Study subjects of both gender in an age group of 30 to 70 were selected for the study. Serum Hs CRP, Fasting Blood sugar and serum lipid profile were estimated after overnight fasting condition. After the biochemical estimation, values were entered in an Excel sheet and level of test and control group was statistically analyzed by using Student's t-test using SPSS software. The values were expressed in Mean ± Standard Deviation (SD) and The status of serum Hs CRP, fasting Blood Sugar and Lipid Profile Parameters were shown a statistically significant difference (p<0.01) between Control and Test groups. The result of the study points out that the elevated level serum Hs-CRP and Fasting Blood Sugar can be used as predictive markers of Hyperlipidemia.

Download Full-text

A STUDY ON SOMATIC DNA DAMAGES IN HYPERTENSIVE YOUNG ADULTS AND ITS CORRELATION WITH BIOCHEMICALAND DEMOGRAPHIC PARAME

10.36106/ijsr/1034356 ◽

2020 ◽

pp. 1-4

Author(s):

Sumina Cheriyan ◽

Deepti G N ◽

Dinesh Roy D ◽

Jaideep Mahendra ◽

Viji Krishnan

Keyword(s):

Oxidative Stress ◽

Dna Damage ◽

Young Adults ◽

Blood Sugar ◽

Venous Blood ◽

Fasting Blood Sugar ◽

Abdominal Circumference ◽

Control Group ◽

Cross Sectional ◽

Dna Damages

Introduction: Incidence of hypertension is increasing in young population. Aggressive control is mandatory to preserve and protect public health in India. Several socio-demographic, anthropometric, environmental, lifestyle, biochemical and genetic factors contribute for the development of hypertension in young adults. Hypertension and its chronic complications are also linked to oxidative stress and DNA damage. Methods: The cross sectional study involves 180 young hypertensives between the age group of 18 – 39 years and 140 apparently healthy age and sex matched controls. After obtaining relevant history, anthropometric measurements were taken. Socio-demographic characters were recorded using proforma. After taking written informed consent, five ( 5 ml) of venous blood was collected after 8-12 hours of fasting. 2 ml of blood was transferred aseptically to a sodium heparinised vacutainer for evaluating somatic DNA damages by Cytokinesis-block Micronuclei assay (CBMN assay). Remaining 3 ml of blood is allowed to clot; serum separated and was used for other biochemical investigations such as fasting blood sugar, lipid profile, urea, creatinine and malondialdehyde (MDA). Statistical analysis done using SPSS software. Results: Fasting blood sugar, Total cholesterol, LDL cholesterol, triglycerides, urea and creatinine were significantly elevated in young hypertensives. Oxidative stress and DNA damage is significantly elevated in young hypertensives compared to control group. BMI and abdominal circumference are also significantly elevated in young hypertensive adults compared to control group. Conclusion: Increased oxidative stress and DNA damage in young hypertensives contribute to the complications associated with hypertension.

Download Full-text

An Analysis of the Hypothalamic-Pituitary-Adrenal Axis Functions in Cirrhotic Rats in Response to Surgical Stress

Surgery Research and Practice ◽

10.1155/2018/7606304 ◽

2018 ◽

Vol 2018 ◽

pp. 1-6

Author(s):

Fahimeh Yarigholi ◽

Ali Zare Mehrjardi ◽

Zahra Azizi ◽

Massoud Baghai Wadji

Keyword(s):

Mortality Rate ◽

Adrenal Gland ◽

Blood Sugar ◽

Hpa Axis ◽

Surgical Stress ◽

Control Group ◽

Hypothalamic Pituitary Adrenal ◽

Significant Difference ◽

The Mean ◽

And Control

Introduction. The activation of hypothalamic-pituitary-adrenal (HPA) axis through severe diseases and stress courses leads to a rise in circulatory cortisol for an adequate response to stress. This axis is one of the important systems that involve in neuroendocrine response to the surgical stress. Hepatoadrenal syndrome that is a manifestation of adrenal insufficiency (AI) in the course of liver disease is described as insufficient production of steroid hormones mainly cortisol due to primary dysfunction of the adrenal gland or secondary malfunction of the HPA axis to provoke the adrenal gland leading to severe illness and increased mortality. Through this evidence, we presented this question as to whether cirrhotic patients have a greater mortality rate than other patients after surgery and if the HPA axis is partly responsible for this phenomenon. Also how the adrenal gland functions during surgery in cirrhotic rats. We conducted this study to assess the effect of cirrhosis on the HPA axis through surgery in cirrhotic rats by evaluating the changes in serum corticosterone level and blood sugar before, immediately, and 30 minutes after surgery. Method. This study was performed in the animal lab approved by the Ethics Committee of Tehran University of Medical Sciences in 2014, on 25 male Wistar rats. Thioacetamide was used for induction of cirrhosis in rats with new method of monitoring weekly changes of rats’ weight which had 100% success in procedure and reduction in mortality rate. Laparotomy was performed on all of the rats during 9–12 in the morning within 10–15 minutes. Laparotomy was chosen as surgical stress because of its simplicity and feasibility. Three blood samples were obtained from each rat immediately after inducing anesthesia, immediately after the conclusion of surgery, and 30 minutes after surgery. The plasma concentration of corticosterone was measured with enzyme-linked immunosorbent assay test. P value of 0.05 or less was considered as statistical significance. Result. Cirrhotic rat group consisted of 15 rats and control group consisted of 10 rats. There was a significant difference in the mean level of corticosterone and blood sugar between the cirrhotic rat group and control group in the 3 time levels (P=0.044/P<0.001). Pairwise comparison of mean corticosterone and blood sugar levels between case (mean: 249.359 ± 3.90) and control (mean: 262.40 ± 4.69) showed a significant difference (P=0.04, 95% CI = 0.30–25.79/P<0.001, 95% CI = 129.62–233.96). Unlike the control group, the level of serum corticosterone was compared in the cirrhotic rat group (group 1) before, immediately, and 30 minutes after surgery, which showed a significant difference in our study (P value = 0.005). However, this result was also significant in comparing the blood sugar in 3 time levels of surgery in the control group (P value < 0.001) but not in the cirrhotic rat group (P value = 0.233). Conclusion. There was a significant rise in corticosterone levels during 3 time levels of surgery in cirrhotic rats; nevertheless, this elevation was significantly lower than the control group. Also the mean level of blood sugar was higher in the control group than in cirrhotic rats. However, this difference was significant in comparison with the same times of surgery between the two groups. These results approximately can substantiate our hypothesis that AI in the field of cirrhosis would also affect the response of HPA axis to stress during and after surgery that can be concomitant with higher rate of cardiovascular unsteadiness incidences, deteriorating the severity of illness and rise in mortality rate.

Download Full-text