scholarly journals The relationship between headache-attributed disability and lost productivity: 2. Empirical evidence from population-based studies in nine disparate countries

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Hallie Thomas ◽  
Simple Futarmal Kothari ◽  
Andreas Husøy ◽  
Rigmor Højland Jensen ◽  
Zaza Katsarava ◽  
...  
Keyword(s):  
Cost Saving ◽  
Medication Overuse Headache ◽  
Cost Effective ◽  
Disability Weight ◽  
Population Based ◽  
Regression Equations ◽  
Headache Disorders ◽  
Global Campaign ◽  
Lost Productivity ◽  
The Relationship

Abstract Background Headache disorders are disabling, with major consequences for productivity, yet the literature is silent on the relationship between headache-attributed disability and lost productivity, often erroneously regarding the two as synonymous. We evaluated the relationship empirically, having earlier found that investment in structured headache services would be cost saving, not merely cost-effective, if reductions in headache-attributed disability led to > 20% pro rata recovery of lost productivity. Methods We used individual participant data from Global Campaign population-based studies conducted in China, Ethiopia, India, Nepal, Pakistan and Russia, and from Eurolight in Lithuania, Luxembourg and Spain. We assessed relationships in migraine and probable medication-overuse headache (pMOH), the most disabling common headache disorders. Available symptom data included headache frequency, usual duration and usual intensity. We used frequency and duration to estimate proportion of time in ictal state (pTIS). Disability, in the sense used by the Global Burden of Disease study, was measured as the product of pTIS and disability weight for the ictal state. Impairment was measured as pTIS * intensity. Lost productivity was measured as lost days (absence or < 50% productivity) from paid work and corresponding losses from household work over the preceding 3 months. We used Spearman correlation and linear regression analyses. Results For migraine, in a linear model, we found positive associations with lost paid worktime, significant (p < 0.05) in many countries and highly significant (p < 0.001) in some despite low values of R2 (0–0.16) due to high variance. With lost household worktime and total lost productivity (paid + household), associations were highly significant in almost all countries, although still with low R2 (0.04–0.22). Applying the regression equations for each country to the population mean migraine-attributed disability, we found pro rata recoveries of lost productivity in the range 16–56% (> 20% in all countries but Pakistan). Analysing impairment rather than disability increased variability. For pMOH, with smaller numbers, associations were generally weaker, occasionally negative and mostly not significant. Conclusion Relief of disability through effective treatment of migraine is expected, in most countries, to recover > 20% pro rata of lost productivity, above the threshold for investment in structured headache services to be cost saving.

scholarly journals The relationship between headache-attributed disability and lost productivity: 1. A review of the literature

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Simple Futarmal Kothari ◽  
Rigmor Hølland Jensen ◽  
Timothy J Steiner
Keyword(s):  
English Language ◽  
Empirical Studies ◽  
Review Of The Literature ◽  
Headache Disorders ◽  
Search Terms ◽  
Lost Productivity ◽  
Text Reading ◽  
Disease Study ◽  
The Relationship ◽  
Language Literature

Abstract Background Headache disorders are disabling and have a significant impact on productivity. The relationship between these two consequences is of considerable economic and political interest. We enquired into it through a systematic search of the English-language literature. Methods We followed PRISMA guidelines in specifying search terms and syntax and in article selection. We used the term “disability” in the search, accepting any meaning that authors attached to it, but this proved problematic. Accordingly, we adopted the definition used in the Global Burden of Disease study. In article selection, we included only those that purported to measure disability as so defined and lost productivity. We reviewed the full texts of those selected. We included further articles identified from review of the bibliographies of selected articles. Results The literature search found 598 studies, of which 21 warranted further review. Their bibliographies identified another four of possible relevance. On full-text reading of these 25, all were rejected. Ten applied incompatible definitions of disability and/or lost productivity. Two did not measure both. Four reported lost productivity but not disability. Eight studies reported and measured both but did not assess the association between them or provide the means of doing so. One was purely methodological. Conclusions The literature is silent on the relationship between headache-attributed disability and lost productivity. In view of its health economic and political importance, empirical studies are required to remedy this. A prerequisite is to clarify what is meant by “disability” in this context.

scholarly journals Primary headache disorders among the adult population of Mongolia: prevalences and associations from a population-based survey

2019 ◽  
Vol 20 (1) ◽  
Author(s):  
Otgonbayar Luvsannorov ◽  
Byambasuren Tsenddorj ◽  
Dorjkhand Baldorj ◽  
Selenge Enkhtuya ◽  
Delgermaa Purev ◽  
...  
Keyword(s):  
Health Policy ◽  
Medication Overuse Headache ◽  
Adult Population ◽  
Population Based ◽  
Local Health ◽  
Headache Disorders ◽  
Primary Headache Disorders ◽  
Local Health Policy ◽  
High Prevalence ◽  
Headache Yesterday

Abstract Background In the ongoing Global Campaign endeavour to improve knowledge and awareness of headache prevalence worldwide, Mongolia is a country of interest. It sits between Russia and China, in which prevalence is, respectively, much higher and much lower than the estimated global mean. We conducted a population-based study in Mongolia both to add to knowledge and to inform local health policy. Methods Using standardized methodology with cluster random sampling, we selected Mongolian adults (aged 18–65 years) from five regions reflecting the country’s diversities. They were interviewed by trained researchers, cold-calling at their homes, using the Headache-Attributed Restriction, Disability, Social Handicap and Impaired Participation (HARDSHIP) structured questionnaire following pilot-testing. ICHD-3 beta diagnostic criteria were applied. Results N = 2043 (mean age 38.0 [±13.4] years, 40% urban-dwelling and 60% rural), with a non-participation proportion of 1.7%. Males were somewhat underrepresented, for which corrections were made. The crude 1-year prevalence of any headache was 66.1% (95% CI: 64.0–68.2%), with a strong female preponderance (OR: 2.2; p < 0.0001). Age- and gender-adjusted prevalences were: migraine 23.1% (for females, OR = 2.2; p < 0.0001); tension-type headache (TTH) 29.1% (no gender difference); probable medication-overuse headache (pMOH) 5.7% (trending towards higher in females); other headache on ≥15 days/month 5.0% (for females, OR = 2.2; p = 0.0008). Unclassified cases were only 35 (1.7%). Any headache yesterday was reported by 410 (20.1%; for females, OR = 2.4; p < 0.0001). Only pMOH showed a strong association with age, peaking in middle years with a 5-fold increase in prevalence. Migraine showed a consistent association with educational level, while pMOH showed the reverse, and was also more common among other groups than among participants who were single (never married). Migraine was less common among rural participants than urban (OR: 0.80; p = 0.0326), while pMOH again showed the reverse (OR: 2.4; p < 0.0001). Finally, pMOH (but not migraine or TTH) was significantly associated with obesity (OR: 1.8; p = 0.0214). Conclusion Headache disorders are common in Mongolia, with, most notably, a very high prevalence of headache on ≥15 days/month corroborated by the high prevalence of headache yesterday. The picture is very like that in Russia, and dissimilar to China. There are messages for national health policy.

Lifestyle intervention to prevent diabetes in men and women with impaired glucose tolerance is cost-effective

2007 ◽  
Vol 23 (2) ◽  
pp. 177-183 ◽  
Author(s):  
Peter Lindgren ◽  
Jaana Lindström ◽  
Jaakko Tuomilehto ◽  
Matti Uusitupa ◽  
Markku Peltonen ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Cost Saving ◽  
Glucose Tolerance ◽  
Impaired Glucose Tolerance ◽  
Lifestyle Intervention ◽  
Intervention Program ◽  
Lifestyle Modification ◽  
Screening Program ◽  
Cost Effective ◽  
Population Based

Objectives: The Finnish Diabetes Prevention Study (DPS) was a randomized intervention program that evaluated the effect of intensive lifestyle modification on the development of diabetes mellitus type 2 in patients with impaired glucose tolerance. As such, a program is demanding in terms of resources; it is necessary to assess whether it would be money well spent. This determination was the purpose of this study.Methods: We developed a simulation model to assess the economic consequences of an intervention like the one studied in DPS in a Swedish setting. The model used data from the trial itself to assess the effect of intervention on the risk of diabetes and on risk factors for cardiovascular disease. Results from the United Kingdom Prospective Diabetes Study were used to estimate the risk of cardiovascular disease and stroke. Cost data were derived from Swedish studies. The intervention was assumed to be applied to eligible patients from a population-based screening program of 60-year-olds in the County of Stockholm from which the baseline characteristics of the patients was used.Results: The model predicted that implementing the program would be cost-saving from the healthcare payers' perspective. Furthermore, it was associated with an increase in estimated survival of .18 years. Taking into consideration the increased consumption by patients due to their longer survival, the predicted cost-effectiveness ratio was 2,363€ per quality-adjusted life-year gained.Conclusions: Lifestyle intervention directed toward high-risk subjects would be cost-saving for the healthcare payer and highly cost-effective for society as a whole.

THE MODEL FOR MANAGING INVESTMENTS IN THE MOSCOW ENVIRONMENT BASED ON A POWER REGRESSION EQUATION

2020 ◽  
Vol 2 (7) ◽  
pp. 91-99
Author(s):  
E. V. KOSTYRIN ◽  
◽  
M. S. SINODSKAYA ◽  
Keyword(s):  
Solid Waste ◽  
Influencing Factors ◽  
Pair Correlation ◽  
Approximation Error ◽  
Regression Equation ◽  
Regression Equations ◽  
The Impact ◽  
The Relationship ◽  
Average Approximation ◽  
Average Approximation Error

The article analyzes the impact of certain factors on the volume of investments in the environment. Regression equations describing the relationship between the volume of investment in the environment and each of the influencing factors are constructed, the coefficients of the Pearson pair correlation between the dependent variable and the influencing factors, as well as pairwise between the influencing factors, are calculated. The average approximation error for each regression equation is determined. A correlation matrix is constructed and a conclusion is made. The developed econometric model is implemented in the program of separate collection of municipal solid waste (MSW) in Moscow. The efficiency of the model of investment management in the environment is evaluated on the example of the growth of planned investments in the activities of companies specializing in the export and processing of solid waste.

Pound Wise and Penny Foolish? Weight Loss and The Dynamics of Health Care Spending

2011 ◽  
Vol 14 (2) ◽  
Author(s):  
Thomas G Koch
Keyword(s):  
Weight Loss ◽  
Cost Savings ◽  
Cost Effective ◽  
Economic Consequences ◽  
Health Care Spending ◽  
Order Of Magnitude ◽  
Dynamic Measures ◽  
The Cost ◽  
The Impact ◽  
The Relationship

Current estimates of obesity costs ignore the impact of future weight loss and gain, and may either over or underestimate economic consequences of weight loss. In light of this, I construct static and dynamic measures of medical costs associated with body mass index (BMI), to be balanced against the cost of one-time interventions. This study finds that ignoring the implications of weight loss and gain over time overstates the medical-cost savings of such interventions by an order of magnitude. When the relationship between spending and age is allowed to vary, weight-loss attempts appear to be cost-effective starting and ending with middle age. Some interventions recently proven to decrease weight may also be cost-effective.

scholarly journals Sodium Metasilicate Cemented Analogue Material and Its Mechanical Properties

2016 ◽  
Vol 2016 ◽  
pp. 1-17 ◽  
Author(s):  
Songlin Yue ◽  
Yanyu Qiu ◽  
Pengxian Fan ◽  
Pin Zhang ◽  
Ning Zhang
Keyword(s):  
Complex Geometry ◽  
Sodium Metasilicate ◽  
Raw Material ◽  
Fine Aggregate ◽  
Regression Equations ◽  
Deformation And Failure ◽  
Orthogonal Experiments ◽  
Low Modulus ◽  
New Type ◽  
The Relationship

Analogue material with appropriate properties is of great importance to the reliability of geomechanical model test, which is one of the mostly used approaches in field of geotechnical research. In this paper, a new type of analogue material is developed, which is composed of coarse aggregate (quartz sand and/or barite sand), fine aggregate (barite powder), and cementitious material (anhydrous sodium silicate). The components of each raw material are the key influencing factors, which significantly affect the physical and mechanical parameters of analogue materials. In order to establish the relationship between parameters and factors, the material properties including density, Young’s modulus, uniaxial compressive strength, and tensile strength were investigated by a series of orthogonal experiments with hundreds of samples. By orthogonal regression analysis, the regression equations of each parameter were obtained based on experimental data, which can predict the properties of the developed analogue materials according to proportions. The experiments and applications indicate that sodium metasilicate cemented analogue material is a type of low-strength and low-modulus material with designable density, which is insensitive to humidity and temperature and satisfies mechanical scaling criteria for weak rock or soft geological materials. Moreover, the developed material can be easily cast into structures with complex geometry shapes and simulate the deformation and failure processes of prototype rocks.

Sign in / Sign up

Export Citation Format

Share Document