Re-emergence of syphilis in women of reproductive age and its association with the increase in congenital syphilis in Mexico during 2010–2019: an ecological study

Abstract Background Syphilis is a sexually transmitted infection that is re-emerging in different parts of the world. This infection can be transmitted during pregnancy, causing neonatal syphilis. The objective of this study was to examine trend in syphilis, congenital syphilis, and neonatal deaths among the Mexican population during 2010–2019. Methods An ecological study was carried out to collect information about the incidence of syphilis, the incidence of congenital syphilis, and the incidence of neonatal death from congenital syphilis. The variables were described considering age, sex, Mexican state, and year. Trends across time (calendar year) were analyzed using linear regression, increases were estimated with 95% confidence intervals, and p < 0.05 was considered statistically significant. Results The incidence of syphilis increased by an average of 0.336 cases/100,000 per year and was higher among women aged 15–19 years (0.693 cases). Cases of congenital syphilis increased from 62 cases in 2010 to 372 cases in 2019; furthermore, the increase in syphilis cases among women aged 20 to 24 years was associated with an increase in cases of congenital syphilis. In 2010, 50% of Mexican states did not report cases of congenital syphilis, but in 2018, only 10% did not report cases of congenital syphilis. Between 2010 and 2018, 83 neonatal deaths were reported, with the highest incidence in 2018 (0.88 deaths/100,000 newborns). Conclusion The incidence of congenital syphilis is increasing in Mexico. As a consequence of the reemergence of syphilis among the population of reproductive age, it is necessary to address and treat syphilis in various population groups.

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Re-emergence of syphilis in women of reproductive age and its association with the increase in congenital syphilis, the case of Mexico during the years 2010-2019

10.21203/rs.3.rs-607054/v1 ◽

2021 ◽

Author(s):

Santa García-Cisneros ◽

Antonia Herrera-Ortiz ◽

Maria Olamendi-Portugal ◽

Miguel A. Sanchez-Aleman

Keyword(s):

Linear Regression ◽

Confidence Intervals ◽

Sexually Transmitted Infection ◽

Congenital Syphilis ◽

Reproductive Age ◽

Women Of Reproductive Age ◽

Transmitted Infection ◽

Sexually Transmitted ◽

The World ◽

Different Parts

Abstract BackgroundSyphilis is a sexually transmitted infection that is re-emerging in different parts of the world. This infection can be transmitted during pregnancy causing neonatal syphilis. The objective of the study was to determine the trend of syphilis, congenital syphilis, and mortality from congenital syphilis among the Mexican population between the years 2010-2019. MethodsWe formed databases about the incidence of syphilis, the incidence of congenital syphilis, cases of congenital syphilis, and deaths of congenital syphilis using information from the Morbidity and Mortality Yearbooks and the Bulletin of the Mexican Ministry of Health, considering age, sex, the states of Mexico, and year. The trend was analyzed using linear regression, the increase was estimated with 95% confidence intervals, and p<0.05 was considered statistically significant. ResultsThe incidence of syphilis increases on average 0.336 cases/100,000, being higher among women aged 15-19 years (0.693 cases). Congenital syphilis has grown, from 62 cases in the year 2010 to 372 cases in the year 2019; the cases of congenital syphilis have relation to the increase of syphilis among women aged 20-24 years. Fifty percent of the states of Mexico without cases of congenital syphilis in 2010, but only 10% in 2018. Between the years 2010 to 2017, 62 deaths from congenital syphilis were reported. ConclusionCongenital syphilis is increasing in Mexico, as a consequence of the reemergence of syphilis among the population of reproductive age, it is necessary to attend to syphilis in various population groups.

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Re-Emergence of Syphilis in Women of Reproductive Age and its Association with the Increase in Congenital Syphilis, The Case of Mexico During the Years 2010-2019

10.21203/rs.3.rs-607054/v2 ◽

2021 ◽

Author(s):

Santa García-Cisneros ◽

Antonia Herrera-Ortiz ◽

Maria Olamendi-Portugal ◽

Miguel A. Sanchez-Aleman

Keyword(s):

Linear Regression ◽

Confidence Intervals ◽

Sexually Transmitted Infection ◽

Congenital Syphilis ◽

Reproductive Age ◽

Women Of Reproductive Age ◽

Transmitted Infection ◽

Sexually Transmitted ◽

The World ◽

Different Parts

Abstract Background: Syphilis is a sexually transmitted infection that is re-emerging in different parts of the world. This infection can be transmitted during pregnancy causing neonatal syphilis. The objective of the study was to determine the trend of syphilis, congenital syphilis, and mortality from congenital syphilis among the Mexican population between the years 2010-2019. Methods. We formed databases about the incidence of syphilis, the incidence of congenital syphilis, cases of congenital syphilis, and deaths of congenital syphilis using information from the Morbidity and Mortality Yearbooks and the Bulletin of the Mexican Ministry of Health, considering age, sex, the states of Mexico, and year. The trend was analyzed using linear regression, the increase was estimated with 95% confidence intervals, and p<0.05 was considered statistically significant. Results. The incidence of syphilis increases on average 0.336 cases/100,000, being higher among women aged 15-19 years (0.693 cases). Congenital syphilis has grown, from 62 cases in the year 2010 to 372 cases in the year 2019; the cases of congenital syphilis have relation to the increase of syphilis among women aged 20-24 years. Fifty percent of the states of Mexico without cases of congenital syphilis in 2010, but only 10% in 2018. Between the years 2010 to 2017, 62 deaths from congenital syphilis were reported. Conclusion. Congenital syphilis is increasing in Mexico, as a consequence of the reemergence of syphilis among the population of reproductive age, it is necessary to attend to syphilis in various population groups.

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Prevalence of High Risk HPV in HIV-Infected Women From Belém, Pará, Amazon Region of Brazil: A Cross-Sectional Study

Frontiers in Public Health ◽

10.3389/fpubh.2021.649152 ◽

2021 ◽

Vol 9 ◽

Author(s):

Jacqueline Cortinhas Monteiro ◽

Ricardo Roberto de Souza Fonseca ◽

Tuane Carolina de Sousa Ferreira ◽

Luana Lorena Silva Rodrigues ◽

Andreza Reis Brasil da Silva ◽

...

Keyword(s):

Cervical Cancer ◽

High Risk ◽

Hpv Infection ◽

Cross Sectional Study ◽

Reproductive Age ◽

Transmitted Infection ◽

Cross Sectional ◽

Multiple Sexual Partners ◽

Sexually Transmitted ◽

High Risk Hpv

Human papillomavirus (HPV) is the most common sexually transmitted infection in the world. Several studies have shown a higher prevalence of HPV infection in HIV-infected women. The aim of this study was to determine the prevalence and the genotype diversity of HPV infection in HIV-infected women. From April 2010 to December 2012 cervical specimens were collected from 169 HIV-infected women who screening for cervical cancer at Reference Unit in Belém. The detection of HPV infection was performed by nested PCR and HPV type was performed using a commercial system. The prevalence of HPV infection was 63.3%. Of the 47 genotyped samples, 40.4% was found positive for high risk-HPV 16 and 12.8% for high risk-HPV 52. HPV infection was predominant in the group of women with no incidence of cytological abnormalities and more prevalent in women of reproductive age, unmarried, low education level, and who reported use condoms during sexual intercourse. It was observed an association between HPV infection and independent variables, such as condom use, multiple sexual partners, and history of sexually transmitted diseases. High-risk types of HPV infection were prevalent in our study. Infection with multiple high-risk HPV genotypes may potentiate the development of cervical cancer in HIV-infected women.

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Association between intensity of STI screening and development of antimicrobial resistance in N. gonorrhoeae in 12 cities in the USA: An ecological study

F1000Research ◽

10.12688/f1000research.15569.3 ◽

2018 ◽

Vol 7 ◽

pp. 1237

Author(s):

Chris R. Kenyon

Keyword(s):

United States ◽

Antimicrobial Resistance ◽

Ecological Study ◽

Geometric Mean ◽

The United States ◽

Transmitted Infection ◽

Sexually Transmitted ◽

Antimicrobial Sensitivity ◽

The Usa ◽

Sex With Men

In this study, we assessed if there was a city-level association between sexually transmitted infection (STI) screening intensity in men who have sex with men and antimicrobial sensitivity in Neisseria gonorrhoeae in the United States, 2007 to 2013. We found positive associations between STI screening intensity and increases in minimum inhibitory concentrations for cefixime and azithromycin, but not ceftriaxone when using change in city geometric mean N. gonorrhoeae MIC between 2005 and 2013.

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Prevalence of sexually transmitted infections at a tertiary hospital in Tamil Nadu

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20173487 ◽

2017 ◽

Vol 6 (8) ◽

pp. 3573

Author(s):

Durga K. ◽

Karthika K.

Keyword(s):

Risk Factors ◽

Sexually Transmitted Infections ◽

Tamil Nadu ◽

Tertiary Hospital ◽

Good Evidence ◽

Reproductive Age ◽

Women Of Reproductive Age ◽

Asymptomatic Group ◽

Major Health Problem ◽

Sexually Transmitted

Background: Sexually transmitted infections (STIs) present a huge burden of disease and adversely affect the reproductive health of people. The disease prevalence is about 6% in India. This study is done to determine the prevalence of STIs in women of reproductive age (15-49yrs) attending gynaec outpatient block at Institute of Obstetrics and Gynaecology, Chennai and to identify the risk factors.Methods: It is a prospective analytical study conducted at IOG from Febraury 2010 to January 2011 where 1000 women of reproductive age attending gynec op were included of which 500 women were asymptomatic and 500 women were symptomatic for STIs. A well-structured proforma was prepared for selection of women, history, examination, investigations and treatment. Asymptomatic women were also screened and treated. Partners were also screened and treated. Depending upon the statistical data, the risk factors were identified and analysed.Results: Overall prevalence of STI was 27.2% of which 22.5% was in symptomatic group and 4.7% in asymptomatic group. Bacterial vaginosis was the commonest STI. The important risk factors identified were age group between 26-30 years, high risk sexual behaviours, poor socioeconomic factors, poor menstrual hygiene and lack of contraception.Conclusions: STIs cause major health problem and it is important to diagnose and treat them at the earliest. The importance of STIs has been more widely recognised since the advent of the HIV/AIDS epidemic, and there is good evidence that their control can reduce HIV transmission. Women diagnosed with one STI should be screened for other STI due to coexistant infections. Screening and treatment of partners and follow-up tests of cure should be performed wherever possible.

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Short Review on Polycystic Ovarian Syndrome

Journal of Medicine ◽

10.3329/jom.v19i1.34843 ◽

2017 ◽

Vol 19 (1) ◽

pp. 49-53

Author(s):

Rabia Farooq

Keyword(s):

Polycystic Ovarian Syndrome ◽

Endocrine System ◽

Short Review ◽

Reproductive Age ◽

Women Of Reproductive Age ◽

The World ◽

Long Time ◽

System Disorder ◽

Ovarian Syndrome

Polycystic ovarian syndrome (PCOS) is a metabolic disease and a common endocrine system disorder among women of reproductive age. Infrequent or prolonged menstrual periods, excess hair growth, acne, and obesity can occur in women with PCOS. Early diagnosis and treatment along with weight loss may reduce the risk of long-term complications. Now a days PCOS is also the cause of infertility. India is PCOS capital of the world. PCOS management is necessary to reduce its long time complications.J MEDICINE Jan 2018; 19 (1) : 49-53

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Aberrant cervical innate immunity predicts onset of dysbiosis and sexually transmitted infections in women of reproductive age

PLoS ONE ◽

10.1371/journal.pone.0224359 ◽

2020 ◽

Vol 15 (1) ◽

pp. e0224359 ◽

Cited By ~ 3

Author(s):

Raina N. Fichorova ◽

Charles S. Morrison ◽

Pai-Lien Chen ◽

Hidemi S. Yamamoto ◽

Yashini Govender ◽

...

Keyword(s):

Innate Immunity ◽

Sexually Transmitted Infections ◽

Reproductive Age ◽

Women Of Reproductive Age ◽

Sexually Transmitted

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Clinical manifestations of neurosyphilis in women of reproductive age

Pediatrician (St Petersburg) ◽

10.17816/ped7257-62 ◽

2016 ◽

Vol 7 (2) ◽

pp. 57-62

Author(s):

Maria L Chuhlovina ◽

Denis V Zaslavsky ◽

Ekaterina A Bichun

Keyword(s):

Rating Scale ◽

Congenital Syphilis ◽

Clinical Manifestations ◽

Reproductive Age ◽

Women Of Reproductive Age ◽

Clinical Dementia Rating ◽

Clock Drawing Test ◽

Mattis Dementia Rating Scale ◽

Moderate Dementia ◽

Dementia Rating Scale

The research objective is investigation of clinical manifestations of neurosyphilis in women of reproductive age. The diagnoses were based on complaints, anamnestic information, neurological examinations, dermatovenerology consultations, serological blood and liquor tests. All the patients underwent psychometric tests. The following methods were used: mini-mental state examination (MMSE), “Frontal Assessment Battery”, Clinical Dementia Rating scale, Clock drawing test, “Information-Memory-Consideration Concentration” test, Mattis Dementia Rating Scale. Nine patients with early neurosyphilis (between the ages of 18 to 40) and eight patients with late neurosyphilis (between the ages of 28 to 43) were surveyed. Syphilitic meningitis (six cases), meningovascular neurosyphilis (three cases) were found in patients with early neurosyphilis. As for the patients with late neurosyphilis, two of them were diagnosed to have syphilitic meningitis, two patients had meningovascular neurosyphilis, two had progressive paralysis, tabes dorsalis was identified in one patient, one had taboparalysis. Only three patients showed specific skin and mucic manifestations. The patients at all the stages of neurosyphilis demonstrated mild cognitive impairments. Moderate dementia was found in one patient with early meningovascular neurosyphilis and one patient with progressive paralysis. This article considers a clinical case of a female patient with early syphilitic meningitis who had a baby with congenital syphilis.

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Features of Pap smears in women of reproductive life with papillomavirus 16, 18

Ukrainian journal of Perinatology and Pediatrics ◽

10.15574/pp.2021.86.96 ◽

2021 ◽

pp. 96-97

Author(s):

Shafag Eldar Aliyeva ◽

Keyword(s):

Cervical Cancer ◽

Epithelial Cells ◽

Pap Smear ◽

Reproductive Age ◽

Pap Smears ◽

Pathological Changes ◽

Women Of Reproductive Age ◽

Hpv 16 ◽

Sexually Transmitted ◽

Cervical Disease

Introduction. According to modern data, cervical diseases do not occur by chance. Precancerous lesions vary from person to person and become invasive over time. The need for specific diagnostic methods for early detection of cervical cancer in women of reproductive age always remains relevant. Over the years, numerous diagnostic, cytological and histological studies have been carried out to identify malignant lesions of the cervix. Human papillomavirus (HPV) is a widespread sexually transmitted infection that affects both women and men around the world and plays an important role in the development of cervical disease. It is the most common sexually transmitted virus in the United States of America. For the first time in 1942, Papanicolaou emphasized the possibility of using smears (PAP smears) from the cervix and from the vagina to diagnose cervical disease. PAP preparations of smears are mainly multilayered flat epithelial cells of the ectocervix and vagina, endocervical cylindrical cells, including mononuclear and polynuclear inflammatory cells that enter the vagina through diapedesis from the surface of the epithelial layer, mixing with the mucoid fluid produced by the endocervical epithelial fluid. Purpose — using objective criteria for cytological examination to identify neoplastic changes in the cervix. Materials and methods. The study included 100 women of reproductive age (18–45 years old) during 2015–2020. Of these, 20 were in the control group (group I — control) and 80 — in the high-risk group for cervical cancer (group II — the main group). Group II women were also divided into 2 subgroups: II A — with pathology of the cervix (n=41), II B — without pathology of the cervix (n=39). The study included patients with a positive result on HPV 16/18 including patients whose PAP smears revealed intracellular damage. Pap smears were included in the study according to the following criteria. The smears contained a sufficient number of squamous epithelial cells and their integrity was preserved. Endocervical cells were monitored in all PAP smears. The examination was carried out with at least 5 cells in each, not completely, and with 2 clusters of endocervical glandular or squamous metaplastic cells. Squamous epithelial cells covered at least 10% of the preparation. Bloody, technically artifactic preparations without clinical data have not been studied. The deficit rate did not exceed 3%, and high interest rates on artifacts were not included in the study. Despite the small number of cells in the presence of abnormal cells, this was unequivocally considered sufficient. Results. Interpretation of PAP smear results identified n=35 ASCUS patients, n=24 LSIL, n=21 HSIL patients in the PAP smear positive reproductive age group. HPV serotypes 16.18 were found in 24 of these patients. In women of the II B subgroup, no pathological changes in the cervix were observed. Conclusions. In women of reproductive age with positive HPV 16, 18, for the diagnosis of precancerous diseases of the cervix, taking pap smears is an integral part of the study. As a result of the study, it was revealed that, despite the absence of a clinical picture, pathological changes at the cell level are detected. Key words: HPV16, 18, ASCUS, LSIL, HSIL, PAP.

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PERILAKU SEKSUAL BERISIKO INFEKSI MENULAR SEKSUAL

Jurnal Ilmiah PANNMED (Pharmacist, Analyst, Nurse, Nutrition, Midwivery, Environment, Dentist) ◽

10.36911/pannmed.v16i1.1024 ◽

2021 ◽

Vol 16 (1) ◽

pp. 150-154

Author(s):

Lenny Irmawaty Sirait

Keyword(s):

Sexually Transmitted Infections ◽

Health Center ◽

Sexual Intercourse ◽

Reproductive Age ◽

P Value ◽

Childbearing Age ◽

District Health ◽

Transmitted Infection ◽

Sexually Transmitted ◽

The Relationship

Sexually Transmitted Infections (STIs) are various infections that can be transmitted from one person to another through sexual contact. The spread of STIs to women and men (90%) occurs through sexual intercourse, both vaginal, anal and oral, the rest through blood products or tissue transfer that has been exposed to pathogens or can be transmitted through medical devices, as well as from mother to fetus in the womb or while birth process. This study aims to determine the relationship between sexual intercourse patterns and the incidence of sexually transmitted infections in women of reproductive age at the Makassar District Health Center, East Jakarta 2019. This research method is a type of quantitative research with a cross-sectional research design, using the inclusion and exclusion criteria for a sample of 55 people, the type of data. primer, measuring instrument questionnaire and laboratory results, analysis of chi square test data. The results showed that out of 46 women of childbearing age who had a poor pattern of sexual relations and sexually transmitted infections were 41 people (89.1%) and 5 people (10.9%) had sexually transmitted infections while 9 people had a pattern of sexual intercourse. well and sexually transmitted infections were 1 person (11.1) and sexually transmitted infections were 8 people (89.9%) pvalue = 0.01 (p <0.05). Conclusion The Relationship between Sexual Relationship Patterns and the Incidence of Sexually Transmitted Infection in Women of Fertile Age at the Makassar District Health Center 2019 (p value = 0.01)

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