scholarly journals Restoration of bilateral motor coordination from preserved agonist-antagonist coupling in amputation musculature

Author(s):  
Tony Shu ◽  
Shan Shan Huang ◽  
Christopher Shallal ◽  
Hugh M. Herr

Abstract Background Neuroprosthetic devices controlled by persons with standard limb amputation often lack the dexterity of the physiological limb due to limitations of both the user’s ability to output accurate control signals and the control system’s ability to formulate dynamic trajectories from those signals. To restore full limb functionality to persons with amputation, it is necessary to first deduce and quantify the motor performance of the missing limbs, then meet these performance requirements through direct, volitional control of neuroprosthetic devices. Methods We develop a neuromuscular modeling and optimization paradigm for the agonist-antagonist myoneural interface, a novel tissue architecture and neural interface for the control of myoelectric prostheses, that enables it to generate virtual joint trajectories coordinated with an intact biological joint at full physiologically-relevant movement bandwidth. In this investigation, a baseline of performance is first established in a population of non-amputee control subjects ($$n = 8$$ n = 8 ). Then, a neuromuscular modeling and optimization technique is advanced that allows unilateral AMI amputation subjects ($$n = 5$$ n = 5 ) and standard amputation subjects ($$n = 4$$ n = 4 ) to generate virtual subtalar prosthetic joint kinematics using measured surface electromyography (sEMG) signals generated by musculature within the affected leg residuum. Results Using their optimized neuromuscular subtalar models under blindfolded conditions with only proprioceptive feedback, AMI amputation subjects demonstrate bilateral subtalar coordination accuracy not significantly different from that of the non-amputee control group (Kolmogorov-Smirnov test, $$P \ge 0.052$$ P ≥ 0.052 ) while standard amputation subjects demonstrate significantly poorer performance (Kolmogorov-Smirnov test, $$P < 0.001$$ P < 0.001 ). Conclusions These results suggest that the absence of an intact biological joint does not necessarily remove the ability to produce neurophysical signals with sufficient information to reconstruct physiological movements. Further, the seamless manner in which virtual and intact biological joints are shown to coordinate reinforces the theory that desired movement trajectories are mentally formulated in an abstract task space which does not depend on physical limb configurations.

Biosfer ◽  
2018 ◽  
Vol 7 (2) ◽  
pp. 22-26
Author(s):  
Rani Rahmahdini ◽  
Diana Vivanti ◽  
Erna Heryanti

A serious environmental problem has occurred due to the negative impact of household waste. Lack of knowledge and awareness of waste processing must be improved through an effective counseling method provided for housewives. The aim of this research was to determine different counseling methods about garbage toward housewives’ knowledge about processing of the household waste. This research carried out on Kampung Pulo, Jakarta Timur on April 2013. A quasi-experiment method with a randomized control group pretest-posttest design was used. Counseling methods of demonstration and movie display were given in two different groups as the treatment. Instrument of knowledge test was used to collect data. The normality testing of Kolmogorov-Smirnov test and the Homogeneity testing of F-test at α = 0.05 resulted a normal distribution and homogenous data. The hypothesis testing of t-test showed t count > t table on 3.34 > 2.03 which rejected the H0, meaning that different knowledge level about processing of the household waste obtained from different method of counseling. It is concluded that, demonstration method was more effective than movie display to increase the housewives’ knowledge about processing of the household waste.


Biosfer ◽  
2018 ◽  
Vol 7 (2) ◽  
pp. 4-9
Author(s):  
Dwiatri Harjanti Uswatun Hasanah ◽  
Tri Murtiati ◽  
Sri Rahayu

Understanding about narcotics, psychotropics, and addictive substances is beneficial to prevent drugs abuse among students. One of the ways to provide knowledge about this topic may be done by counseling. This research was aimed to know the effect of narcotics, psychotropics, and addictive substances counseling toward students’ knowledge about drug abuse. The study was conducted in SMK Negeri 34 Jakarta during May 2012 using an experimental method. Simulation method was performed in experimental class whether speech method was applied in control group. This research design was pretest-posttest control group using multiple choice knowledge test instrument. Samples were selected by simple random sampling. Normality testing of the Kolmogorov – Smirnov test and homogeneity testing of t-test showed a normal distribution and homogenous data. Meanwhile, hypothesis testing done by t-test at α = 0.05 result was –ttable < tcount < ttable at -3.23 < -0.67 < 2.03, meaning that there was no effect of narcotics, psychotropics, and addictive substances counseling toward students’ knowledge about drugs abuse.


2016 ◽  
Vol 4 (3) ◽  
pp. 242-249
Author(s):  
Yunita Yudaningsih ◽  
Nico L Kana ◽  
Untung Sujianto

Rumah Sakit Umum Daerah Kota Semarang merupakan rumah sakit milik Pemerintah Kota Semarang. Kinerja perawat merupakan bagian integral dalam meningkatkan mutu pelayanan yang diberikan rumah sakit, sehingga kinerja perawat harus selalu ditingkatkan. Tujuan penelitian ini adalah untuk menganalisis pengaruh pelatihan kepemimpinan spiritual terhadap peningkatan kinerja ketua tim keperawatan dalam memberikan pelayanan keperawatan di rumah sakit. Jenis penelitian adalah penelitian kuantitatif meggunakan design pre –post test with control group dengan cara melakukan intervensi, berupa kegiatan pelatihan dengan materi kepemimpinan spiritual pada kelompok eksperimen. Setelah dua bulan pelaksanaan pelatihan, dilakukan pengukuran kinerja ketua tim keperawatan, untuk melihat pengaruh kegiatan pelatihan tentang kepemimpinan spiritual terhadap peningkatan kinerja ketua tim keperawatan pada kelompok eksperimen. Cara pengambilan data kinerja ketua tim dengan menggunakan kuesioner yang diisi oleh perawat pelaksana. Populasi adalah seluruh ketua tim keperawatan dengan total sampling Analisis data menggunakan T test dengan Uji One Sample Kolmogorov-Smirnov Test untuk melihat pengaruh pelatihan terhadap peningkatan kinerja ketua tim keperawatan. Hasil penelitian menunjukkan rerata peningkatan kinerja ketua tim keperawatan pada kelompok ekperimen yang diukur sebelum pelaksanaan pelatihan, dengan nilai sebesar 58,66 dalam katagori kurang. Adapun setelah dilakukan pelatihan kepemimpinan spiritual terjadi peningkatan kinerja ketua tim keperawatan menjadi sebesar 77,04 dalam katagori baik. Dari analisis data mendapatkan dengan nilai mean (-43,422) artinya terjadi kecenderungan peningkatan kinerja ketua tim keperawatan yang cukup bermakna pada kelompok eksperimen, yaitu sebesar 43,422. Nilai tersebut menunjukkan bahwa pelatihan tentang kepemimpinan spiritual berpengaruh terhadap peningkatan kinerja ketua tim keperawatan Rumah Sakit Umum Daerah Kota Semarang.  


2019 ◽  
Vol 1 (1) ◽  
pp. 85
Author(s):  
Sonia Hadiyanti ◽  
Harmayetty Harmayetty ◽  
Ika Yuni Widyawati

AbstrakTHIS ARTICLE IS RETRACTED DUE TO REDUNDANT PUBLICATION. Berdasarkan penelitian terbaru, olahraga/ latihan mempunyai efek yang signifikan dalam menurunkan glukosa darah penelitian ini bertujuan untuk mengidentifikasi efek dari model latihan isometrik terhadap kadar glukosa darah pada mencit yang dikondisikan mengalami diabetes mellitus. Penelitian ini adalah penelitian eksperimen murni (True Experiment). Menggunakan rancangan eksperimen The Randomise Post Test Only Control Group Design. Sampel adalah mencit jantan dengan berat 20-27 gram. 27 ekor mencit jantan dibagi menjadi tiga kelompok yaitu kelompok control terdiri dari mencit normal yang diinjeksi NaCl sebagai placebo. Kelompok kedua adalah mencit diabetes yang tidak diberikan latihan isometrik dan kelompok ketiga adalah mencit diabetes diberikan latihan isometrik. Kelompok kedua dan ketiga diinjeksi streptozotocin (STZ) untuk meginduksi DM. Setelah 48 jam diinjeksi, kedua kelompok diberikan glukosa oral (Dextrose-40%). Kelompok ketiga diberikan latihan isometrik menggunakan treadmill selama 23.31 menit dengan kecepatan 21 cm/detik dan sudut elevasi 0°. Data dianalisa menggunakan One Kolmogorov-Smirnov test, ANOVA test dan Least Significance Difference (LSD) dengan α<0.05. Analisa One Kolmogorov-Smirnov test p=0.94 pada kelompok kontrol, p=0.50 pada kelompok mencit diabetes, and p=0.19 pada kelompok perlakuan. Hasil ANOVA tes adalah p=0.08. Hasil LSD untuk gluksa darah adalah p=0.23 untuk kelompok perlakuan. Hal ini mungkin terjadi karena pada kelompok kedua terdapat 2 mencit dengan glukosa darah normal dan pada kelompok ketiga kadar glukosa darah awal tidak diketahui. Sehingga, mungkin saja kelompok tersebut juga memiliki kadar glukosa darah normal. Dapat disimpulkan bahwa tidak ada efek latihan isometrik dalam menurunkan kadar glukosa darah. Penelitian selanjutnya disarankan mengidentifikasi lebih jauh tentang frekuensi dan intensitas latihan isometrik yang dapat mempengaruhi penurunan kadar glukosa darah.


Author(s):  
Nurhusnul Khatimah ◽  
Khaeruman Khaeruman ◽  
Yusran Khery

Lack of awareness of: courtesy, dishonesty while performing individual tasks, being dishonest in daily tests, and not being obedient to the teacher's instructions is due to the lack of Imtaq process. To solve it is by integrating Imtaq values with learning materials. This study aims to determine the effect of integration of Imtaq values on the material of atomic structure to motivation and religious character. The research was conducted in class X MAN 1 Mataram during August until September 2014. The subjects of the study were students of class X IPA-2 (as experiment) and X IPS-3 (as control) were 37 and 39 students respectively. This research is a quasi- experiment with posttest-control group design. Data of research result are motivation and religious character. The instrument of data collection is a questionnaire of motivation and questionnaire of religious character which has been tested its validity and reliability on 76 subjects who have the same characteristics of age and level of education with the subject of research. The data were analyzed using normality test followed by kolmogorov-smirnov test. The results showed that there is an effect of integration of imtaq values on the material of atomic structure to motivation and religious character.


2020 ◽  
Vol 17 (1) ◽  
pp. 1-8
Author(s):  
Ahwan Abdul ◽  
Fridah Wahyu Safitri ◽  
Rantika Purbowati

Fennel plants are plants that have various traditional properties, such as facilitating breast milk or lactagogum. The aim of this research was to give ethanol extract of fennel fruit to increase the level of the hormone prolactin in lactating mice, so that the milk produced was increased. Subjects consisted of 12 postpartum female rats, divided into 1 control group (1% CMC Na) and 3 treatment groups (doses of 100, 500 and 1000 mg / Kg BW). Fennel fruit extract was given orally for each group for 14 days, after the treatment of blood samples were taken and centrifuged, the serum was read by Elisa Reader. The data obtained were analyzed using the Kolmogorov-Smirnov test, one-way ANAVA and Tukey's Multiple Comparison (post hoc test). Fennel fruit extract given from a dose of 100; 500 and 1000 mg / kg BW can significantly increase levels of the hormone prolactin (p 0.05) in nursing mice, respectively by 42.11; 44.26 and 43.83 ng / mL compared to controls (32.64 ng/mL).


2018 ◽  
Vol 7 (1) ◽  
pp. 28-35
Author(s):  
Winanda Rizki Bagus Santosa ◽  
Riyono Riyono

Honey and crystals sugar was complementary materials for wound care in a modern era. In other easy to get it, the curative characteristic in the honey and crystal sugar, it can to cure of the injury soon. The injury can easy to heal so the cost is cheap. This research aims to determine comparation of the effect of honey compress and crystals sugar compress on the process of wound healing in mice. This type of research is a True Experiment Randomized Design with research design Post Test Only Control Group Design conducted on 15 white rats received artificial injury. The sample selected by RCT (Randomized Control Trial) it divided into three groups, namely honey compress treatment group (n = 5), crystal sugar compress the treated group (n = 5), and the control group (n = 5). Independent variables that influence honey compress and the crystals sugar compress, while the dependent variable healed wound (edema, hyperemia, pus, granulation) on the observation every day for seven days. The data obtained,  than it  analyzed using Kolmogorov-Smirnov test by level of significance p <0.05. The results showed the influence statistic significantly granting of honey compress and sugar crystals compress third day of observation. Kolmogorov-Smirnov test (edema p = 0.013, hyperemia p = 0.013, pus p = 0.013, and granulation p = 0.013). Compresses can be summed giving honey and crystals sugar compress significantly effect the process of wound healing. Based on these results, it  suggested in other that use a pack of honey or crystals sugar compress can be applied as comprehensive wound care


2017 ◽  
Vol 68 (2) ◽  
pp. 358-361
Author(s):  
Camelia Busila ◽  
Mariana Cretu Stuparu ◽  
Aurel Nechita ◽  
Camelia Ana Grigore ◽  
Gabriela Balan

The study is a prospective and operational one, ant its was conducted on 58 patients with diabetes type 1 and 2. The patients sex distribution was homogenious and they come from both rural and urban environment. The statistical analisys was carried out using the programme SPSS 17.0 for Windows. The distribution normality was cheked using the Kolmogorov - Smirnov Z test. he values of glycemia, glycosylated hemoglobin, lipid panel, blood pressure have been measured and compared to the ones belonging to the control group.


2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Mohammadreza Azimi ◽  
Seyed Ahmad Rasoulinejad ◽  
Andrzej Pacut

AbstractIn this paper, we attempt to answer the questions whether iris recognition task under the influence of diabetes would be more difficult and whether the effects of diabetes and individuals’ age are uncorrelated. We hypothesized that the health condition of volunteers plays an important role in the performance of the iris recognition system. To confirm the obtained results, we reported the distribution of usable area in each subgroup to have a more comprehensive analysis of diabetes effects. There is no conducted study to investigate for which age group (young or old) the diabetes effect is more acute on the biometric results. For this purpose, we created a new database containing 1,906 samples from 509 eyes. We applied the weighted adaptive Hough ellipsopolar transform technique and contrast-adjusted Hough transform for segmentation of iris texture, along with three different encoding algorithms. To test the hypothesis related to physiological aging effect, Welches’s t-test and Kolmogorov–Smirnov test have been used to study the age-dependency of diabetes mellitus influence on the reliability of our chosen iris recognition system. Our results give some general hints related to age effect on performance of biometric systems for people with diabetes.


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