scholarly journals Patented technologies for schistosomiasis control and prevention filed by Chinese applicants

2021 ◽  
Vol 10 (1) ◽  
Author(s):  
Yan-Hong Xiong ◽  
Xue-Nian Xu ◽  
Bin Zheng

Abstract Background Many valuable and productive patented technologies have been developed to control schistosomiasis in China in the past 70 years. We conducted a research to analyse patented technologies for schistosomiasis control and prevention filed by Chinese applicants for determining the future patent layout. Methods The patent databases of China National Intellectual Property Administration and Baiten were comprehensively searched, and patented technologies for schistosomiasis control and prevention, published between January 1950 and December 2020 filed by Chinese applicants were sorted on 30 December 2020. The patent types, technical fields, and patent development trends were analysed using patent indexing. Results There are 184 valid schistosomiasis control technology patents, among them 128 invention patents. The patents related to schistosomiasis control and prevention technology have gone through the germination, growth, and maturity stages. These phases correspond with three phases in schistosomiasis control in China. The main technical aspects were fundamental research (n = 37), detection (n = 13), chemotherapy (n = 61), and armamentarium/devices (n = 73), of which the number of patents for detection for diagnosis was smaller. The top three specialised technical fields for patents subgroups, focusing on antiparasitic agents, DNA or RNA, vectors and medicines, of which schistosomicides are the major dominant subgroup. Conclusions We recommend that technologies to be patented for schistosomiasis control and prevention be focused on detection, preliminary studies for molecular detection methods should be significantly enhanced, and patent layout must be performed, which will, in turn, promote accuracy of early diagnosis, not only in humans but also in livestock. It is necessary to develop more anti-schistosomal drugs safely and effectively, exceptionally eco-friendly molluscicides and herbal extracts anti-schistosomes, improve treatment, develop vaccines for use in humans. Graphic abstract

2012 ◽  
Vol 2012 ◽  
pp. 1-18 ◽  
Author(s):  
Nicholas Johnson ◽  
Katja Voller ◽  
L. Paul Phipps ◽  
Karen Mansfield ◽  
Anthony R. Fooks

Arthropod-borne viruses (arboviruses) have been responsible for some of the most explosive epidemics of emerging infectious diseases over the past decade. Their impact on both human and livestock populations has been dramatic. The early detection either through surveillance or diagnosis of virus will be a critical feature in responding and resolving the emergence of such epidemics in the future. Although some of the most important emerging arboviruses are human pathogens, this paper aims to highlight those diseases that primarily affect livestock, although many are zoonotic and some occasionally cause human mortality. This paper also highlights the molecular detection methods specific to each virus and identifies those emerging diseases for which a rapid detection methods are not yet developed.


2018 ◽  
Author(s):  
Pallabi Ghosh ◽  
Domenic Forte ◽  
Damon L. Woodard ◽  
Rajat Subhra Chakraborty

Abstract Counterfeit electronics constitute a fast-growing threat to global supply chains as well as national security. With rapid globalization, the supply chain is growing more and more complex with components coming from a diverse set of suppliers. Counterfeiters are taking advantage of this complexity and replacing original parts with fake ones. Moreover, counterfeit integrated circuits (ICs) may contain circuit modifications that cause security breaches. Out of all types of counterfeit ICs, recycled and remarked ICs are the most common. Over the past few years, a plethora of counterfeit IC detection methods have been created; however, most of these methods are manual and require highly-skilled subject matter experts (SME). In this paper, an automated bent and corroded pin detection methodology using image processing is proposed to identify recycled ICs. Here, depth map of images acquired using an optical microscope are used to detect bent pins, and segmented side view pin images are used to detect corroded pins.


2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Tao Zhang ◽  
Shuqi Wang ◽  
Duoquan Wang ◽  
Sarah Auburn ◽  
Shenning Lu ◽  
...  

Abstract Background Although autochthonous malaria cases are no longer reported in Anhui Province, China, imported malaria has become a major health concern. The proportion of reported malaria cases caused by Plasmodium ovale spp. increased to levels higher than expected during 2012 to 2019, and showed two peaks, 19.69% in 2015 and 19.35% in 2018. Methods A case-based retrospective study was performed using data collected from the China Information System for Disease Control and Prevention (CISDCP) and Information System for Parasitic Disease Control and Prevention (ISPDCP) from 2012 to 2019 to assess the trends and differences between Plasmodium ovale curtisi (P. o. curtisi) and Plasmodium ovale wallikeri (P. o. wallikeri). Epidemiological characteristics were analyzed using descriptive statistics. Results Plasmodium o. curtisi and P. o. wallikeri were found to simultaneously circulate in 14 African countries. Among 128 patients infected with P. ovale spp., the proportion of co-infection cases was 10.16%. Six cases of co-infection with P. ovale spp. and P. falciparum were noted, each presenting with two clinical attacks (the first attack was due to P. falciparum and the second was due to P. ovale spp.) at different intervals. Accurate identification of the infecting species was achieved among only 20.00% of cases of P. ovale spp. infection. At the reporting units, 32.17% and 6.96% of cases of P. ovale spp. infection were misdiagnosed as P. vivax and P. falciparum infections, respectively. Conclusion The present results indicate that the potential of P. ovale spp. to co-infect with other Plasmodium species has been previously underestimated, as is the incidence of P. ovale spp. in countries where malaria is endemic. P. o. curtisi may have a long latency period of > 3 years and potentially cause residual foci, thus posing challenges to the elimination of malaria in P. ovale spp.-endemic areas. Considering the low rate of species identification, more sensitive point-of-care detection methods need to be developed for P. ovale spp. and introduced in non-endemic areas.


Author(s):  
D.W. Baxter

In 1975, medical neurology is a well established, viable, growing specialty in Canada. There are now almost 250 neurologists scattered across the country, congregated largely in the hospitals associated with our 16 medical schools. Neurology is a major component of the undergraduate curriculum in each of these schools, and the majority of schools are approved for postgraduate training in our specialty. The Royal College has certified an average of 18 new neurologists each year for the past five years. In our hospitals we work closely with our internist and neurosurgical colleagues and we receive the support of highly competent teams of neuropathologists, clinical electrophysiologists and neuroradiologists. We believe that we provide a generally high standard of consultation service to our medical and surgical colleagues. We accept direct responsibility for patients suffering from a host of acute neurological problems, but we accept long term responsibility for very few. We do a great deal of teaching at both the undergraduate and graduate levels. In fact, the major role which neurology plays in undergraduate curricula, and the stimulus of postgraduate education, probably have been the two most influential factors shaping the number, work patterns and distribution of Canadian neurologists. Many of us are engaged in clinical investigation, but relatively few medical neurologists in Canada make fundamental research contributions.


2021 ◽  
pp. 1-10
Author(s):  
Jane A. Kent ◽  
Kate L. Hayes

The field of exercise physiology has enjoyed tremendous growth in the past 40 years. With its foundations in the natural sciences, it is an interdisciplinary field that is highly relevant to human performance and health. The focus of this review is on highlighting new approaches, knowledge, and opportunities that have emerged in exercise physiology over the last four decades. Key among these is the adoption of advanced technologies by exercise physiologists to address fundamental research questions, and the expansion of research topics to range from molecular to organismal, and population scales in order to clarify the underlying mechanisms and impact of physiological responses to exercise in health and disease. Collectively, these advances have ensured the position of the field as a partner in generating new knowledge across many scientific and health disciplines.


MRS Bulletin ◽  
1986 ◽  
Vol 11 (3) ◽  
pp. 17-29
Author(s):  
Gerold Yonas

Al the plenary session held December 4, 1985 during the annual MRS Fall Meeting in Boston, Dr. Gerold Yonas was the keynote speaker. He was introduced to the packed ballroom by 1985 MRS President Elton N. Kauftnann.Kaufmann: To introduce our plenary address this evening, I would like to make a few remarks on the context in which it is being presented. Iam sure you are all aware that materials research, as most fields of science, is a field where it is rare indeed that one can cleanly separate the technical aspects of a program from the social, economic, and political aspects. This evening's topic is certainly no exception. It involves the U.S. government's Strategic Defense Initiative, or SDI for short. It has broad technical and political implications and has raised highly contentious issues of both technical feasibility and political appropriateness. It is in every source of news available today. This evening we want to focus on those technical aspects of SDI which involve materials and which should therefore be of interest to this audience.Recently, in Space Business News, John McTague, Acting Director of OSTP (Office of Science and Technology Policy), indicated that “the technology of Swords and the technology of Plowshares have much in common.” Of course the degree of commonality between the Swords and the Plowshares becomes greateras one goes to more fundamental research. In the same article Gerold Yonas indicated that “several aspects of SDI are likely to have enormous implications in the private sector with spinoffs directed into every part of the economy.” In addition to the technical materials aspect of the program those larger issues will certainly impact our lives. In that spirit we want to make this presentation so you can evaluate the program with a maximum amount of information. Of course, because this is a publicly controversial issue, I need to stress that the Society is not endorsing one particular view or another. But, we are strongly advocating the wide dissemination of information on a topic such as this.


2018 ◽  
Vol 15 (1) ◽  
Author(s):  
Ameh S. James ◽  
Shawn Todd ◽  
Nina M. Pollak ◽  
Glenn A. Marsh ◽  
Joanne Macdonald

2021 ◽  
pp. 41-52
Author(s):  
Edyta Kot ◽  
◽  
Anna Jurga ◽  
Ewa Kartasińska ◽  
Ewa Lewansowska ◽  
...  

Biometrics is one of the basic detection techniques used in law enforcement activities on a daily basis. Like other techniques, it is constantly changing. This article aims to provide an overview of what was in the past, what is now, and what will be in the near future. It presents the selected methods of collecting some of the data, as well as the systems used to process them. In addition, practical guidance is provided on how individual biometric data should be collected and, for specific cases, it explains why the data collection procedure is carried out in one way and not another, and what it means for its subsequent processing. As problems sometimes arise during recovery of the material they have been presented together with an overview of the reasons for that. In addition to information on the technical aspects, the article also includes references to legal acts regulating issues related to biometrics.


Foods ◽  
2020 ◽  
Vol 9 (8) ◽  
pp. 1069 ◽  
Author(s):  
Abdo Hassoun ◽  
Ingrid Måge ◽  
Walter F. Schmidt ◽  
Havva Tümay Temiz ◽  
Li Li ◽  
...  

Animal origin food products, including fish and seafood, meat and poultry, milk and dairy foods, and other related products play significant roles in human nutrition. However, fraud in this food sector frequently occurs, leading to negative economic impacts on consumers and potential risks to public health and the environment. Therefore, the development of analytical techniques that can rapidly detect fraud and verify the authenticity of such products is of paramount importance. Traditionally, a wide variety of targeted approaches, such as chemical, chromatographic, molecular, and protein-based techniques, among others, have been frequently used to identify animal species, production methods, provenance, and processing of food products. Although these conventional methods are accurate and reliable, they are destructive, time-consuming, and can only be employed at the laboratory scale. On the contrary, alternative methods based mainly on spectroscopy have emerged in recent years as invaluable tools to overcome most of the limitations associated with traditional measurements. The number of scientific studies reporting on various authenticity issues investigated by vibrational spectroscopy, nuclear magnetic resonance, and fluorescence spectroscopy has increased substantially over the past few years, indicating the tremendous potential of these techniques in the fight against food fraud. It is the aim of the present manuscript to review the state-of-the-art research advances since 2015 regarding the use of analytical methods applied to detect fraud in food products of animal origin, with particular attention paid to spectroscopic measurements coupled with chemometric analysis. The opportunities and challenges surrounding the use of spectroscopic techniques and possible future directions will also be discussed.


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