Mast cells positive to c-kit receptor and to tryptase in normal to cancer pancreatic tissue and the correlation with angiogenesis.

2020 ◽  
Vol 38 (15_suppl) ◽  
pp. e16502-e16502
Author(s):  
Carmelo Laface ◽  
Michele Ammendola ◽  
Valeria Zuccalà ◽  
Francesco Luposella ◽  
Nicola Zizzo ◽  
...  
Keyword(s):  
Standard Deviation ◽  
Mast Cells ◽  
Secretory Granules ◽  
Mean Value ◽  
T Test ◽  
Ductal Adenocarcinoma ◽  
Cancer Tissue ◽  
Test Analysis ◽  
Kit Receptor ◽  
The Mean

e16502 Background: In the last years published studies demonstrated that mast cells (MCs) contain pro-angiogenic factors associated with tumoral angiogenesis. Tryptase is the most abundant and potent pro-angiogenic substance contained in MCs secretory granules and it can be released in tumour microenvironment. Up to now few data have been published on the role of MCs in angiogenesis in both pancreatic ductal adenocarcinoma cancer tissue (PDACT) and adjacent normal tissue (ANT). Methods: In this study MCs density positive to C-Kit receptor (MCDP-C-KitR), MCs density positive to tryptase (MCDPT), MCs area positive to tryptase (MCAPT), angiogenesis in terms of microvascular density (MVD) and endothelial area (EA) were evaluated by immunohistochemistry and image analysis in both PDACT and ANT. All tissue samples were obtained from 45 patients with stage T2-3N0-1M0 (by AJCC for Pancreas Cancer Staging 7th Edition) who had undergone surgery. For each analyzed tissue parameter mean ± standard deviation was evaluated in both PDACT and ANT and differences were evaluated by Student t-test. Each analysed tissue parameter was then correlated each other by Pearson t-test analysis. Results: The mean value ± standard deviation (SD) regarding MCDP-C-KitR, MCDPT, MCAPT, MVD and EA in TT was 14.69±4.57, 13.31± 4,23, 171.41±62,39 µ2, 29.11±7.93, 201.82±70.05 µ2 respectively and the mean value ± SD in ANT was 5.61 ± 2.39, 5.13 ± 2.03, 54.43 ± 16.73 µ2, 11.45 ± 4.96, 67.60 ± 21.96 µ2, respectively. Differences in terms of mean value ± SD between PDACT and ANT were significant for each analyzed tissue biomarker (p ranged from 0,001 to 0,004 by t-test analysis; Table). Data demonstrated that MCDP-C-KitR MCDPT, MCAPT, MVD and EA significantly increased from ANT to PCT. In PCT it was showed a correlation between MCDP-C-KitR and MCDPT (r = 0.87, p = 0.01), MCDP-C-KitR and MVD (r = 0.74, p = 0.02), MCDP-C-KitR and MCAPT (r = 0.81, p = 0.01), MCDPT and MVD (r = 0.72, p = 0.02), MCD-C-KitR and EA (r = 0.73, p = 0.02), MCDPT and MCAPT (r = 0.85, p = 0.01), MCAPT and MVD (r = 0.76, p = 0.02), MCAPT and EA (r = 0.66, p = 0.03), MCDPT and EA (r = 0.69, p = 0.03), MVD and EA (r = 0.82, p = 0.01). Conclusions: Our data suggest that assessed tissue parameters increased from ANT to PDACT and that MCs are associated with angiogenesis in PDACT. On this basis inhibition of MCs by tyrosine kinase inhibitors such as masitinib or inhibition of tryptase by gabexate mesylate may be a novel antiangiogenetic approach in pancreatic cancer therapy.

scholarly journals Mast Cells Positive for c-Kit Receptor and Tryptase Correlate with Angiogenesis in Cancerous and Adjacent Normal Pancreatic Tissue

Cells ◽  
2021 ◽  
Vol 10 (2) ◽  
pp. 444
Author(s):  
Michele Ammendola ◽  
Giuseppe Currò ◽  
Carmelo Laface ◽  
Valeria Zuccalà ◽  
Riccardo Memeo ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Mast Cells ◽  
Kinase Inhibitors ◽  
Pancreatic Tissue ◽  
T Test ◽  
Ductal Adenocarcinoma ◽  
Test Analysis ◽  
Kit Receptor ◽  
Student’S T ◽  
Few Data

Background: Mast cells (MCs) contain proangiogenic factors, in particular tryptase, associated with increased angiogenesis in several tumours. With special reference to pancreatic cancer, few data have been published on the role of MCs in angiogenesis in both pancreatic ductal adenocarcinoma tissue (PDAT) and adjacent normal tissue (ANT). In this study, density of mast cells positive for c-Kit receptor (MCDP-c-KitR), density of mast cells positive for tryptase (MCDPT), area of mast cells positive for tryptase (MCAPT), and angiogenesis in terms of microvascular density (MVD) and endothelial area (EA) were evaluated in a total of 45 PDAT patients with stage T2–3N0–1M0. Results: For each analysed tissue parameter, the mean ± standard deviation was evaluated in both PDAT and ANT and differences were evaluated by Student’s t-test (p ranged from 0.001 to 0.005). Each analysed tissue parameter was then correlated to each other one by Pearson t-test analysis (p ranged from 0.01 to 0.03). No other correlation among MCDP-c-KitR, MCDPT, MCAPT, MVD, EA and the main clinical–pathological characteristics was found. Conclusions: Our results suggest that tissue parameters increased from ANT to PDAT and that mast cells are strongly associated with angiogenesis in PDAT. On this basis, the inhibition of MCs through tyrosine kinase inhibitors, such as masitinib, or inhibition of tryptase by gabexate mesylate may become potential novel antiangiogenetic approaches in pancreatic cancer therapy.

scholarly journals Pengaruh Pelatihan Kader Posbindu Terhadap Perilaku Deteksi Dini Hipertensi Pada Usia Dewasa

2020 ◽  
Vol 5 (1) ◽  
pp. 43-52
Author(s):  
Asri ◽  
Sigit Mulyono ◽  
Uswatul Khasanah
Keyword(s):  
Early Detection ◽  
Total Sample ◽  
Mean Value ◽  
T Test ◽  
Test Analysis ◽  
Before And After ◽  
Post Test ◽  
Change In The Mean ◽  
The Mean ◽  
Paired T Test

The problem of hypertension in adulthood is very important to be a concern because it can cause both acute and chronic diseases such as heart and blood vessel disease, Posbindu cadre training is an activity carried out as an effort to improve skills and knowledge of early detection of hypertension so that the presence of cadres who are the spearhead in health services in the community are able to detect hypertension early. The purpose of this study was to determine the effect of posbindu cadre training on early detection of hypertension in adulthood. This research design uses the Quasi One Group Experiment pre-test Post Test with Paired T-Test. The population in this study was all people suffering from hypertension with a total sample of 84 people. The results showed that there was a change in the mean value before and after the training that was equal to 82 then to 87. The results of the Paired T-test analysis showed that there was an influence of the posbindu cadre training on the behavior of early detection of hypertension where the value (P = 0.001).

scholarly journals Model Pembelajaran Advance Organizer: Dampak Terhadap Hasil Belajar Kognitif Peserta Didik

2019 ◽  
Vol 2 (2) ◽  
pp. 150-161
Author(s):  
Levti Norisa Bely ◽  
Saiful Bahri ◽  
Mukarramah Mustari
Keyword(s):  
Significant Influence ◽  
Cognitive Abilities ◽  
Mean Value ◽  
T Test ◽  
Advance Organizer ◽  
Vocational High School ◽  
Test Analysis ◽  
Quasi Experimental ◽  
Advanced Organizer ◽  
The Mean

Abstract: The purpose of this study is 1) To find out whether there is a significant effect with the Advanced Organizer learning model 2) To improve the cognitive abilities of students on the subject of dynamic fluid Vocational High School. The method used in this study is quasi-experimental with the hypothesis that there is no significant influence on the cognitive abilities of students who are taught using advance organizer learning models so that the cognitive abilities of students are increased. The results of this study indicate that there is a significant influence on the cognitive abilities of students who are taught using an advanced organizer model so that the cognitive abilities of students increase. This can be seen from the results of the pretest and posttest in the experimental class has increased. Significant influence can be proven by the test results from the t-test analysis, where in the t-test analysis the value of t-count> t-table or significant value <significant level (0.05) is equal to 21,921> 2,045. While the increase in cognitive abilities of experimental class students can be seen from the results of the mean mean value of students at the pretest that is 40.16, an increase after the posttest results of the mean mean becomes 81.94. This means that there is a very good increase in the cognitive abilities of students due to the influence of the Advanced Organizer of Dynamic Fluid SMK models.Abstrak: Tujuan pada penelitian ini adalah 1) Untuk mengetahui apakah terdapat pengaruh yang signifikan dengan model pembelajaran Advance Organizer 2) Untuk meningkatkan kemampuan kognitif peserta didik pada pokok bahasan fluida dinamis  SMK. Metode yang digunakan pada penelitian ini adalah quasi eksperimen dengan hipotesis ada atau tidak pengaruh yang signifikan terhadap kemampuan kognitif peserta didik yang diajar dengan menggunakan model pembelajaran advance organizer sehingga kemampuan kognitif peserta didik lebih meningkat. Hasil dari penelitian ini menunjukkan bahwa terdapat pengaruh yang signifikan terhadap kemampuan kognitif peserta didik yang diajar dengan menggunakan model advance  organizer sehingga kemampuan kognitif peserta didik meningkat. Hal ini dapat dilihat dari hasil pretest dan posttest pada kelas eksperimen mengalami peningkatan. Pengaruh signifikan dapat terbukti dengan adanya hasil pengujian dari analisis Uji-t ,dimana pada analisis Uji-t  nilai > atau nilai signifikan < taraf signifikan (0.05) yaitu sebesar 21.921 >  2.045. Sedangkan peningkatan kemampuan kognitif peserta didik kelas eksperimen dapat dilihat dari hasil rata-rata nilai mean peserta didik pada pretest yaitu 40.16, terjadi peningkatan setelah posttest hasil rata-rata nilai mean menjadi 81.94. Artinya terjadi peningkatan yang sangat baik pada kemampuan kognitif peserta didik akibat pengaruh dari model Advance Organizer pokok bahasan Fluida Dinamis SMK.

scholarly journals BLACKBOARD APPLICATION TO PROMOTE STUDENTS’ WRITING SKILL AT SENIOR HIGH SCHOOL IN PALEMBANG

2020 ◽  
Vol 7 (2) ◽  
pp. 74-83
Author(s):  
Santi Mayasari ◽  
Marleni Marleni ◽  
Masagus Firdaus
Keyword(s):  
High School ◽  
High School Students ◽  
Positive Influence ◽  
Mean Value ◽  
T Test ◽  
Control Group ◽  
School Students ◽  
Test Analysis ◽  
The Mean ◽  
Experimental Group

The purpose of this study was to improve the writing skills of XI grade high school students in Palembang. Researchers used a quasi method involving two groups of high school students in Palembang (experimental group and control group). The results of the study were (1) the experimental group pretest and the control group found that the experimental group got the lowest score of 21 and the highest was 63, while the control group got the lowest score of 23 and the highest score was 70, (2) the posttest of the experimental group and the Control Group, the results obtained were that the experimental group was able to obtain a mean value greater than the mean value of the control group. (3) Paired t-test; The results of the Pretest-Posttest Experimental Group showed that there was a very significant increase that occurred in the experimental group as a result of the implementation of LMS in the experimental group students' writing learning, the results of the Independent t-Test were obtained that the mean value of the experimental group was greater than the mean value of the control group, based on the results independent test analysis, it was found that the sig. (two-tailed) which is 0.000 with t-obtained 14,433. This can be interpreted that there is a positive influence on the application of LMS-based learning methods for the writing ability of high school students. Then, it can be seen that the F test value is 0.379 with sig. 0.539.

PERBEDAAN PENGARUH COGNITIVE THERAPY (CT) DAN LOGO THERAPY TERHADAP DEPRESI PADA PASIEN DENGAN HEMODIALISIS DI RS WAVA HUSADA KEPANJEN

2017 ◽  
Vol 3 (2) ◽  
Author(s):  
Nia Agustiningsih ◽  
Setyawati Soeharto ◽  
Rinik Eko Kapti
Keyword(s):  
Cognitive Therapy ◽  
Hemodialysis Patient ◽  
Sampling Procedure ◽  
Mean Value ◽  
T Test ◽  
Physical Aspect ◽  
Test Design ◽  
Test Analysis ◽  
Post Test ◽  
Quasi Experimental

Abstract : Patient with chronical diease such as Hemodialysis more likely need psycotherapy because until now medical atention only focus on physical aspect. Psycotherapy that can be used on Hemodialysis that going through depression is cognitive therapy and logo therapy. This study was to analysed the difference of influence between cognitive therapy and logo therapy on Hemodialysis patient that going through depression. This study was used quasi experimental pre–post test design. Respondent taking part in this study was 15 respondent for cognitive therapy and 15 respondent for logo therapy with puporsive sampling procedure. Study was conducted on Hemodialysis unit on RS Wava Husada Kepanjen from 21 April until 26 Mey 2017. Data analysis used on this study was dependent t test  and independent t test. Dependent t test  analysis showed  significant value is 0,000 (less than < 0,05).Analysis showed  significant value is 0,000 (less than < 0,05) that means there is difference between cognitive therapy and logo therapy to decrease depression on hemodialysis patient with mean value cognitive therapy (1,62) dan logo therapy (3,82). Conclussion on this study is that logo therapy more effective to reduce depression on Hemodialysis patient than cognitive therapy so logo therapy can applicated in hemodialysis patient.Keyword : cognitive therapy, logo therapy, depression in hemodialysis patient Abstrak : Pasien dengan penyakit kronis dengan hemodialisis diperlukan psikoterapi karena selama ini fokus penanganan di pelayanan kesehatan hanya pada masalah fisik. Psikoterapi yang bisa digunakan pada pasien hemodialisis yang mengalami depresi adalah cognitive therapy dan logo therapy. Penelitian ini bertujuan untuk menganalisis perbedaan pengaruh cognitive therapy dan logo therapy terhadap depresi pada pasien dengan hemodialisis. Penelitian ini menggunakan desain penelitian quasi experimental pre – post test design. Jumlah responden dalam penelitian ini 15 responden untuk kelompok cognitive therapy dan 15 responden untuk kelompok logo therapy yang didapatkan dengan menggunakan tehnik purposive sampling. Penelitian dilakukan di unit hemodialisis RS Wava Husada Kepanjen mulai tanggal 21 April – 26 Mei 2017. Pemberian terapi dilakukan oleh peneliti sendiri yang telah mendapatkan lisensi dari perawat spesialis jiwa. Analisis data yang digunakan dalam penelitian ini adalah dependent t test dan independent t test. Hasil analisis dependent t test  pada kelompok sebelum dan setelah diberikan cognitive therapy dan logo therapy didapatkan hasil nilai signifikansi 0,000 < 0,05 yang berarti bahwa ada perbedaan skor depresi antara sebelum dan sesudah diberikan pemberian cognitive therapy dan logo therapy  Sedangkan hasil analisis independent t test menunjukkan bahwa nilai signifikansi 0,000 < 0,05 yang berarti  ada perbedaan yang bermakna antara cognitive therapy dan logo therapy dalam menurunkan depresi pada pasien dengan hemodialisis yaitu dengan rata – rata penurunan terhadap depresi untuk cognitive therapy dan logo therapy masing – masing yaitu 1,62 dan 3,86.  Hal ini berarti bahwa logo therapy lebih efektif menurunkan depresi pada pasien hemodialisis dari pada cognitive therapy. Berdasarkan hasil penelitian tersebut diharapkan bahwa logo therapy bisa diaplikasikan sebagai alternatif psikoterapi pada pasien hemodialisis.Kata Kunci: cognitive therapy, logo therapy, depresi pada pasien hemodialisis

scholarly journals Blood Oxygenation Level Dependent Magnetic Resonance Imaging (MRI), Dynamic Contrast Enhanced MRI and Diffusion Weighted MRI for Benign and Malignant Breast Cancer Discrimination: A Preliminary Experience

Cancers ◽  
2021 ◽  
Vol 13 (10) ◽  
pp. 2421
Author(s):  
Roberta Fusco ◽  
Vincenza Granata ◽  
Mauro Mattace Raso ◽  
Paolo Vallone ◽  
Alessandro Pasquale De Rosa ◽  
...  
Keyword(s):  
Standard Deviation ◽  
Univariate Analysis ◽  
Mean Value ◽  
Blood Oxygenation ◽  
Breast Lesions ◽  
Dce Mri ◽  
Malignant Lesions ◽  
The Mean ◽  
And Diffusion ◽  
Skewness And Kurtosis

Purpose. To combine blood oxygenation level dependent magnetic resonance imaging (BOLD-MRI), dynamic contrast enhanced MRI (DCE-MRI), and diffusion weighted MRI (DW-MRI) in differentiation of benign and malignant breast lesions. Methods. Thirty-seven breast lesions (11 benign and 21 malignant lesions) pathologically proven were included in this retrospective preliminary study. Pharmaco-kinetic parameters including Ktrans, kep, ve, and vp were extracted by DCE-MRI; BOLD parameters were estimated by basal signal S0 and the relaxation rate R2*; and diffusion and perfusion parameters were derived by DW-MRI (pseudo-diffusion coefficient (Dp), perfusion fraction (fp), and tissue diffusivity (Dt)). The correlation coefficient, Wilcoxon-Mann-Whitney U-test, and receiver operating characteristic (ROC) analysis were calculated and area under the ROC curve (AUC) was obtained. Moreover, pattern recognition approaches (linear discrimination analysis and decision tree) with balancing technique and leave one out cross validation approach were considered. Results. R2* and D had a significant negative correlation (−0.57). The mean value, standard deviation, Skewness and Kurtosis values of R2* did not show a statistical significance between benign and malignant lesions (p > 0.05) confirmed by the ‘poor’ diagnostic value of ROC analysis. For DW-MRI derived parameters, the univariate analysis, standard deviation of D, Skewness and Kurtosis values of D* had a significant result to discriminate benign and malignant lesions and the best result at the univariate analysis in the discrimination of benign and malignant lesions was obtained by the Skewness of D* with an AUC of 82.9% (p-value = 0.02). Significant results for the mean value of Ktrans, mean value, standard deviation value and Skewness of kep, mean value, Skewness and Kurtosis of ve were obtained and the best AUC among DCE-MRI extracted parameters was reached by the mean value of kep and was equal to 80.0%. The best diagnostic performance in the discrimination of benign and malignant lesions was obtained at the multivariate analysis considering the DCE-MRI parameters alone with an AUC = 0.91 when the balancing technique was considered. Conclusions. Our results suggest that the combined use of DCE-MRI, DW-MRI and/or BOLD-MRI does not provide a dramatic improvement compared to the use of DCE-MRI features alone, in the classification of breast lesions. However, an interesting result was the negative correlation between R2* and D.

Rigorous time-domain analysis of statistically oriented graphene sheet fluctuations

2017 ◽  
Vol 36 (5) ◽  
pp. 1351-1363 ◽  
Author(s):  
Athanasios N. Papadimopoulos ◽  
Stamatios A. Amanatiadis ◽  
Nikolaos V. Kantartzis ◽  
Theodoros T. Zygiridis ◽  
Theodoros D. Tsiboukis
Keyword(s):  
Monte Carlo ◽  
Standard Deviation ◽  
Finite Difference ◽  
Surface Waves ◽  
Time Domain ◽  
Finite Difference Time Domain ◽  
Mean Value ◽  
Content Type ◽  
The Mean ◽  
Difference Time

Purpose Important statistical variations are likely to appear in the propagation of surface plasmon polariton waves atop the surface of graphene sheets, degrading the expected performance of real-life THz applications. This paper aims to introduce an efficient numerical algorithm that is able to accurately and rapidly predict the influence of material-based uncertainties for diverse graphene configurations. Design/methodology/approach Initially, the surface conductivity of graphene is described at the far infrared spectrum and the uncertainties of its main parameters, namely, the chemical potential and the relaxation time, on the propagation properties of the surface waves are investigated, unveiling a considerable impact. Furthermore, the demanding two-dimensional material is numerically modeled as a surface boundary through a frequency-dependent finite-difference time-domain scheme, while a robust stochastic realization is accordingly developed. Findings The mean value and standard deviation of the propagating surface waves are extracted through a single-pass simulation in contrast to the laborious Monte Carlo technique, proving the accomplished high efficiency. Moreover, numerical results, including graphene’s surface current density and electric field distribution, indicate the notable precision, stability and convergence of the new graphene-based stochastic time-domain method in terms of the mean value and the order of magnitude of the standard deviation. Originality/value The combined uncertainties of the main parameters in graphene layers are modeled through a high-performance stochastic numerical algorithm, based on the finite-difference time-domain method. The significant accuracy of the numerical results, compared to the cumbersome Monte Carlo analysis, renders the featured technique a flexible computational tool that is able to enhance the design of graphene THz devices due to the uncertainty prediction.

Synchronous Issue of IR-Based Large Scale Volume Localization System

2014 ◽  
Vol 496-500 ◽  
pp. 1643-1647
Author(s):  
Ying Feng Wu ◽  
Gang Yan Li
Keyword(s):  
Standard Deviation ◽  
Mobile Robot ◽  
Large Volume ◽  
Large Scale ◽  
Image Acquisition ◽  
Mean Value ◽  
Network Synchronization ◽  
Localization System ◽  
Localization Performance ◽  
The Mean

IR-based large scale volume localization system (LSVLS) can localize the mobile robot working in large volume, which is constituted referring to the MSCMS-II. Hundreds cameras in LSVLS must be connected to the control station (PC) through network. Synchronization of cameras which are mounted on different control stations is significant, because the image acquisition of the target must be synchronous to ensure that the target is localized precisely. Software synchronization method is adopted to ensure the synchronization of camera. The mean value of standard deviation of eight cameras mounted on two workstations is 12.53ms, the localization performance of LSVLS is enhanced.

A STUDY ON THE EFFECTIVENESS OF USING ALPHABET CARDS GAME IN TEACHING VOCABULARY FOR COMMERCIAL BUSINESS ADMINISTRATION STUDENTS

2017 ◽  
Vol 1 ◽  
pp. 54
Author(s):  
Arita Destianingsih ◽  
Ari Satria
Keyword(s):  
Business Administration ◽  
Mean Value ◽  
T Test ◽  
Control Group ◽  
Business Administration Students ◽  
Post Test ◽  
Quasi Experimental ◽  
The Mean ◽  
Experimental Group ◽  
Administration Students

The aim of this study was to know the effectiveness of the use of alphabet cards game as interesting tool to explain vocabularies and it make it easier to remember their meanings. This study belongs to the quasi experimental research and presents pre-test, post test and to investigate the effect of using alphabet cards game on vocabulary mastery of commercial business administration students. The participants were the students from commercial business administration students at the third semester (N=54) of State Polytechnic Bengkalis and divided into two groups. Both groups were taught vocabulary, however, the experimental group students who are exposed to alphabet cards game and the controlled group students who received conventional method. Pre-test and post-test were given to both experimental group students and controlled group students. The score of the vocabulary tests were compared through independent sample t-test. The mean value of pre-test of experimental class was 61.35, while the control class was 52.23. After learning using alphabet card games in experimental class the mean value obtained in post-test was 78.85, while in control class was 59.04.  The improved of learning outcomes can be seen from the level of significance was 0.000 and it was lower than t test 0.000<0.05.  It means that the hypothesis null is not accepted. Therefore, it can be concluded that the score of the students in learning vocabulary between the experimental group and control group was significantly different. The experimental group students who learned vocabulary using alphabet cards game had increased their vocabulary mastery.

Precise computation of the direct and indirect topographic effects of Helmert's 2nd method of condensation using SRTM30 digital elevation model

2011 ◽  
Vol 1 (4) ◽  
pp. 305-312 ◽  
Author(s):  
Y. Wang
Keyword(s):  
Standard Deviation ◽  
Digital Elevation Model ◽  
Outer Zone ◽  
Mean Value ◽  
Constant Density ◽  
Topographic Effects ◽  
Topographic Effect ◽  
Digital Elevation ◽  
The Mean ◽  
Elevation Model

Precise computation of the direct and indirect topographic effects of Helmert's 2nd method of condensation using SRTM30 digital elevation modelThe direct topographic effect (DTE) and indirect topographic effect (ITE) of Helmert's 2nd method of condensation are computed using the digital elevation model (DEM) SRTM30 in 30 arc-seconds globally. The computations assume a constant density of the topographic masses. Closed formulas are used in the inner zone of half degree, and Nagy's formulas are used in the innermost column to treat the singularity of integrals. To speed up the computations, 1-dimensional fast Fourier transform (1D FFT) is applied in outer zone computations. The computation accuracy is limited to 0.1 mGal and 0.1cm for the direct and indirect effect, respectively.The mean value and standard deviation of the DTE are -0.8 and ±7.6 mGal over land areas. The extreme value -274.3 mGal is located at latitude -13.579° and longitude 289.496°, at the height of 1426 meter in the Andes Mountains. The ITE is negative everywhere and has its minimum of -235.9 cm at the peak of Himalayas (8685 meter). The standard deviation and mean value over land areas are ±15.6 cm and -6.4 cm, respectively. Because the Stokes kernel does not contain the zero and first degree spherical harmonics, the mean value of the ITE can't be compensated through the remove-restore procedure under the Stokes-Helmert scheme, and careful treatment of the mean value in the ITE is required.

Sign in / Sign up

Export Citation Format

Share Document