scholarly journals Flavonoid Glycosides from Siparuna gigantotepala Leaves and Their Antioxidant Activity

2016 ◽  
Vol 64 (5) ◽  
pp. 502-506 ◽  
Author(s):  
Harlen Gerardo Torres Castañeda ◽  
Ana Julia Colmenares Dulcey ◽  
José Hipólito Isaza Martínez
Keyword(s):  
Antioxidant Activity ◽  
Flavonoid Glycosides

Chemical characterization and in vivo antioxidant activity of parsley (Petroselinum crispum) aqueous extract

2020 ◽  
Vol 11 (6) ◽  
pp. 5346-5356
Author(s):  
Neide Mara de Menezes Epifanio ◽  
Lynn Rykiel Iglesias Cavalcanti ◽  
Karine Falcão dos Santos ◽  
Priscila Soares Coutinho Duarte ◽  
Piotr Kachlicki ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Aqueous Extract ◽  
Chemical Characterization ◽  
Flavonoid Glycosides ◽  
Petroselinum Crispum

Twenty-nine flavonoid glycosides were identified in the aqueous extract (PC) of Petroselinum crispum var. crispum leaves and apiin, the major compound, was isolated thereof.

scholarly journals Evaluation of Antioxidant Capacity ofSolanum sessiliflorum(Cubiu) Extract: AnIn VitroAssay

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Diego Rocha de Lucena Herrera Mascato ◽  
Janice B. Monteiro ◽  
Michele M. Passarinho ◽  
Denise Morais Lopes Galeno ◽  
Rubén J. Cruz ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Antioxidant Capacity ◽  
Antioxidant Activities ◽  
Flavonoid Glycosides ◽  
Specific Staining ◽  
Native Populations ◽  
Chemical Groups ◽  
Solanaceae Family ◽  
Hydroethanolic Extract

Cubiu is a vegetable of Solanaceae family, native to the Amazon, which is widely distributed through Brazil, Peru, and Colombia. It is used in food, medicine, and cosmetics by native populations. Research has shown that cubiu extracts have antioxidant activities with great biological relevance. We performed a phytochemical screening to identify the main chemical groups that could confer antioxidant activity to this extract. Several tests and qualitative precipitation specific staining for major classes of secondary metabolites were used. Antioxidant capacityin vitrotests (DPPH and ABTS) were also used to assess the extract’s ability to sequester free radicals of 70% hydroethanolic and aqueous extracts of cubiu flour. Alkaloids, organic acids, phenols, flavonoid glycosides, and coumarins were found in the hydroethanolic extract while the aqueous extract presented anthocyanins, gums, tannins and mucilage, amino groups, and volatile and fixed acids. Forin vitrotests, theIC50value obtained in the DPPH assay was 606.3 ± 3.5 μg/mL while that for the ABTS assay was 290.3 ± 10.7 µg/mL. Although cubiu extracts present chemical compounds directly related to antioxidant activity, our results show that it has a low antioxidant activity. Additional studies will be needed to isolate and characterize specific compounds to further assess antioxidant activity.

scholarly journals Identification of phenolic secondary metabolites from Schotia brachypetala Sond. (Fabaceae) and demonstration of their antioxidant activities in Caenorhabditis elegans

2016 ◽  
Author(s):  
Mansour Sobeh ◽  
Esraa A ElHawary ◽  
Herbenya Peixoto ◽  
Rola M Labib ◽  
Heba Handoussa ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Caenorhabditis Elegans ◽  
Nuclear Translocation ◽  
Antioxidant Activities ◽  
In Vitro Assays ◽  
Flavonoid Glycosides ◽  
Alcoholic Extract ◽  
C Elegans

Background: Schotia brachypetala Sond. (Fabaceae) is an endemic tree of Southern Africa whose phytochemistry and pharmacology were slightly studied.The present work aimed at profiling the major phenolics compounds present in the hydro-alcoholic extract from S. brachypetala leaves (SBE) using LC/HRESI/MS/MS and NMR and prove their antioxidant capabilities using novel methods. Methods: In vitro assays; DPPH, TEAC persulfate decolorizing kinetic and FRAP assays, and in vivo assays: Caenorhabditis elegans strains maintenance, Intracellular ROS in C. elegans, Survival assay, GFP expression and Subcellular DAF-16 localization were employed to evaluate the antioxidant activity. Results: More than forty polyphenols ,including flavonoid glycosides, galloylated flavonoid glycosides, isoflavones, dihydrochalcones, procyanidins, anthocyanins, hydroxybenzoic acid derivatives, hydrolysable tannins, and traces of methylated and acetylated flavonoid derivatives were identified. Three compounds were isolated and identified from the genus Schotia for the first time, namely gallic acid, myricetin-3-O-α-L-1C4-rhamnoside and quercetin-3-O-L-1C4-rhamnoside.The tested extract was able to protect the worms against juglone induced oxidative stress and attenuate the reactive oxygen species (ROS) accumulation. SBE was also able to attenuate the levels of heat shock protein (HSP) expression. Discussion: A pronounced antioxidant activity in vivo, which can be attributed to its ability to promote the nuclear translocation of DAF-16/FOXO, the main transcription factor regulating the expression of stress response genes. The remarkable antioxidant activity in vitro and in vivo correlates to SBE rich phenolic profile.

scholarly journals The Effect of Adding the Leaves and Fruits of Morus alba to Rape Honey on Its Antioxidant Properties, Polyphenolic Profile, and Amylase Activity

Molecules ◽  
2019 ◽  
Vol 25 (1) ◽  
pp. 84 ◽  
Author(s):  
Monika Tomczyk ◽  
Michał Miłek ◽  
Ewelina Sidor ◽  
Ireneusz Kapusta ◽  
Wojciech Litwińczuk ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Phenolic Content ◽  
Antioxidant Properties ◽  
Inhibitory Effect ◽  
Flavonoid Glycosides ◽  
Total Phenolic ◽  
Antioxidant Compounds ◽  
Mulberry Leaves ◽  
Hydrolyzing Enzymes ◽  
Polyphenolic Profile

Two various species of mulberry (Morus sp.) were selected to enrich rape honey with dried leaves or lyophilized fruits (4% w/v). Finally, fruits and leaves of the ‘Ukraińska’ clone were introduced into the honey during creaming in concentrations from 1 to 4% w/v. The total phenolic content, antioxidant activity, anthocyanins content, and polyphenolic profile were tested in plant extracts and enriched honeys. Moreover, α-glucosidase, β-galactosidase, and diastase activities were investigated in honeys. For mulberry extracts, chlorogenic acid isomers and rutin were considered main antioxidant compounds. The antioxidant activity of honey enriched with mulberry leaves increased even more than 50 times, due to introducing numerous phenolic acids and flavonoid glycosides. A significant decrease in the diastase activity in honey depending on the content of added mulberry leaves (almost 50% decrease in the case of 4% addition) was found, suggesting the inhibitory effect of honey with mulberry leaves against carbohydrate hydrolyzing enzymes.

scholarly journals Dietary Burden of Phenolics per Serving of “Mountain Tea” (Sideritis) from Macedonia and Correlation to Antioxidant Activity

2011 ◽  
Vol 6 (9) ◽  
pp. 1934578X1100600 ◽  
Author(s):  
Jasmina Petreska ◽  
Marina Stefova ◽  
Federico Ferreres ◽  
Diego. A. Moreno ◽  
Francisco. A. Tomás-Barberán ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Antioxidant Capacity ◽  
Phenolic Content ◽  
Flavonoid Glycosides ◽  
Total Phenolic ◽  
Equal Distribution ◽  
Water Extracts ◽  
Aerial Parts ◽  
Phenolics Content ◽  
Points Of View

This work was afforded from 2 points of view, phytochemical evaluation and relation to antioxidant activity and dietary burden of phenolics of a cup of “Mountain tea”, a drink obtained by domestic infusion of Sideritis. Phytochemically, two extraction protocols using water and methanol as solvent were used for comparison. Methanol and boiling water extracts (by domestic infusion procedure) showed that extracts were rich in bound forms of phenolics such as hydroxycinnamic acids, phenylethanoid glycosides and flavonoid glycosides. The total phenolic content for Sideritis species ranged around 190 mg per serving (2 g infusion bag) for methanol extracts and around 72 mg per serving in water extracts. Among the two different Macedonian Sideritis species, Sideritis raeseri (wild growing) showed the highest phenolics content in both extracts (212 mg and 89 mg per serving, respectively). Concerning the phenolic content in the different aerial parts, leaf was the richest plant organ in phenolics followed by flower and stem with the lowest amount. The methanol extract from Sideritis raeseri (wild growing) showed the highest antioxidant capacity as shown by DPPH, ABTS and FRAP assays. The antioxidant capacity was linearly correlated with phenolic content. Nutritionally, the dietary burden of phenolics of a “Mountain tea” bag for domestic infusion (serving size) was established at 89 mg for an homogeneous and equal distribution of the different aerial parts (leaf, flower and stem). However, and according to our results a rate of 60% leaf and 40% flower would increase the content of bioavailable phenolics and also the total phenolics content of a serving bag of “Mountain tea”.

scholarly journals Inhibition of Digestive Enzymes and Antioxidant Activity of Extracts from Fruits of Cornus alba, Cornus sanguinea subsp. hungarica and Cornus florida–A Comparative Study

Plants ◽  
2020 ◽  
Vol 9 (1) ◽  
pp. 122
Author(s):  
Joanna Truba ◽  
Iwona Stanisławska ◽  
Marta Walasek ◽  
Wioleta Wieczorkowska ◽  
Konrad Woliński ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Digestive Enzymes ◽  
Flavonoid Glycosides ◽  
Cornus Florida ◽  
Fruit Extract ◽  
Cornus Alba ◽  
Biological Potential ◽  
Phytochemical Profile ◽  
Dpph Scavenging ◽  
Dpph Scavenging Assay

The fruits of some Cornus species (dogwoods) are used in traditional medicine and considered potential anti-diabetic and hypolipemic agents. The aim of the study was to determine the ability of extracts from Cornus alba (CA), Cornus florida (CF), and Cornus sanguinea (CS) to inhibit digestive enzymes namely α-amylase, pancreatic lipase, and α-glucosidase, as well as isolation of compounds from plant material with the strongest effect. In addition, the phytochemical profile and antioxidant activity of extracts from three dogwoods were compared with HPLC-DAD-MS/MS and DPPH scavenging assay, respectively. Among the aqueous-ethanolic extracts, the activity of α-amylase was the most strongly inhibited by the fruit extract of CA (IC50 = 115.20 ± 14.31 μg/mL) and the activity of α-glucosidase by the fruit of CF (IC50 = 38.87 ± 2.65 μg/mL). Some constituents of CA fruit extract, such as coumaroylquinic acid, kaempferol, and hydroxytyrosol derivatives, were isolated. Among the three species of dogwood studied, the greatest biological potential was demonstrated by CA extracts, which are sources of phenolic acids and flavonoid compounds. In contrast, iridoid compounds or flavonoid glycosides found in fruits of CF or CS extracts do not play a significant role in inhibiting digestive enzymes but exert antioxidant activity.

Phytochemical screening and antioxidant activity of a edible, medicinally important plant taxa Mollugo pentaphylla L. (Molluginaceae)

2016 ◽  
Vol 5 (07) ◽  
pp. 4707
Author(s):  
Debasree Ghosh ◽  
Prarthita Samanta ◽  
Amal Kumar Mondal* ◽  
Sanjukta Mondal
Keyword(s):  
Antioxidant Activity ◽  
Ascorbic Acid ◽  
Volatile Oil ◽  
The Other ◽  
Flavonoid Glycosides ◽  
Phytochemical Screening ◽  
High Concentration ◽  
Medicinal Value ◽  
Phytochemical Compounds ◽  
Phytochemical Constituents

Mollugo pentaphylla L. is a medicinally important plants in India. Many rural peoples are consumed this plants as a food mainly leaf and stem portion. But the other parts like stem and root of this plant is also has a great medicinal value. The objective of the present study to evaluate the identification of phytochemical constituents that are present on this plants. In qualitative analysis, the phytochemical compounds such as carbohydrates, proteins, polyphenols, carotenoid, ascorbic acid, alkaloid, tannin, flavonoid, glycosides, volatile oil etc. Besides this, these plants also have antioxidant potential in high concentration.

scholarly journals New Flavonoids from Baeckea Frutescens and their Antioxidant Activity

2008 ◽  
Vol 3 (5) ◽  
pp. 1934578X0800300 ◽  
Author(s):  
Tran Hong Quang ◽  
Nguyen Xuan Cuong ◽  
Chau Van Minh ◽  
Phan Van Kiem
Keyword(s):  
Antioxidant Activity ◽  
Ethyl Acetate Extract ◽  
Radical Scavenging ◽  
2D Nmr ◽  
Flavonoid Glycosides ◽  
Dpph Radical ◽  
Aerial Parts ◽  
Baeckea Frutescens ◽  
New Compounds ◽  
Dpph Radical Scavenging

From the ethyl acetate extract of the aerial parts of Baeckea frutescens, a new flavonoid, 6,8-di- C-methylkaempferol (1), and three new flavonoid glycosides, 6,8-di- C-methylkaempferol 3- O-α-L-rhamnopyranoside (2), 6- C-methylquercetin 3- O-α-L-rhamnopyranoside (3), and 6- C-methylquercetin 4′- O-β-D-glucopyranoside (4), along with four known flavonoids were isolated. Their structures were elucidated by extensive spectroscopic methods including 1D and 2D NMR experiments, as well as ESI-MS analysis. All the new compounds were tested for their antioxidant activity in the 1,1-diphenyl-2-pecrylhydrazyl (DPPH) radical scavenging assay system. Compounds 3 and 4 showed potent activity with IC50 values of 12.1 ± 0.5 and 13.5 ± 0.9 (μM), respectively.

scholarly journals Narrow-Banded UVB Affects the Stability of Secondary Plant Metabolites in Kale (Brassica oleracea var. sabellica) and Pea (Pisum sativum) Leaves Being Added to Lentil Flour Fortified Bread: A Novel Approach for Producing Functional Foods

Foods ◽  
2019 ◽  
Vol 8 (10) ◽  
pp. 427 ◽  
Author(s):  
Klopsch ◽  
Baldermann ◽  
Voss ◽  
Rohn ◽  
Schreiner ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Functional Foods ◽  
Ultraviolet B ◽  
Flavonoid Glycosides ◽  
Uvb Radiation ◽  
Plant Metabolites ◽  
Minor Response ◽  
Secondary Plant Metabolites ◽  
Lentil Flour ◽  
Secondary Plant

Young kale and pea leaves are rich in secondary plant metabolites (SPMs) whose profile can be affected by ultraviolet B (UVB) radiation. Carotenoids and flavonoids in kale and pea exposed to narrow-banded UVB, produced by innovative light-emitting diodes (LEDs), and subsequently used for breadmaking were investigated for the first time, thus combining two important strategies to increase the SPMs intake. Breads were also fortified with protein-rich lentil flour. Antioxidant activity in the ‘vegetable breads’ indicated health-promoting effects. Lentil flour increased the antioxidant activity in all of the ‘vegetable breads’. While carotenoids and chlorophylls showed a minor response to UVB treatment, kaempferol glycosides decreased in favor of increasing quercetin glycosides, especially in kale. Additionally, breadmaking caused major decreases in carotenoids and a conversion of chlorophyll to bioactive degradation products. In ‘kale breads’ and ‘pea breads’, 20% and 84% of flavonoid glycosides were recovered. Thus, kale and pea leaves seem to be suitable natural ingredients for producing innovative Functional Foods.

scholarly journals PHYTOCHEMICAL CONSTITUENTS AND ANTIOXIDANT EFFECT OF SOLANUM ROSTRATUM SPECIES FROM ALGERIA T

2018 ◽  
Vol 11 (6) ◽  
pp. 219
Author(s):  
Tebboub Omar ◽  
Labib Noman ◽  
Bouhroume Mohamed ◽  
Feyza Oke Altuntas ◽  
Ibrahim Demirtas
Keyword(s):  
Antioxidant Activity ◽  
Structure Elucidation ◽  
High Performance ◽  
Radical Scavenging ◽  
Chloroform Extract ◽  
Antioxidant Effect ◽  
Flavonoid Glycosides ◽  
Aerial Parts ◽  
Solanum Rostratum ◽  
Radical Scavenging Ability

Objective: The aim of this study was to isolate the constituents and evaluate the antioxidant activity of Solanum rostratum Dunal (Solanaceae) from Algeria. Methods: In this study, phytochemical analyses of the chloroform, ethyl acetate, and n-butanol extracts obtained from the aerial parts of S. rostratum were performed by column chromatography, thin-layer chromatography, and high-performance liquid chromatography techniques. The antioxidant activity was performed by 2,2-diphenyl-1-picrylhydrazyl scavenging assay method.Results: The identification and structure elucidation of the isolated compounds were compared with their nuclear magnetic resonance spectra and the literature led to identify one monoterpene glycoside (linalyl-β-glucopyranoside) (1) and three flavonoid glycosides: Apigenin-7-O-glucoside (2), astragalin (3) and (isorhamnetin-3-O-glucoside (4).Conclusion: This is the first report on the isolation and structure elucidation of compound (1) (linalyl-β-glucopyranoside) and compound (2) (apigenin-7-O-glucoside) from this species. In addition, antioxidant effect of the chloroform extract from S. rostratum was evaluated. The chloroform extract exhibited the remarkable radical scavenging ability (IC50=0066±0.001 mg/mL).

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