scholarly journals Efficacy and Mechanism of Action of Aloe Vera, Cinnamomum Zeylanicum, Curcuma Longa, Garcinia Cambogia, and Garcinia Mangostana Extracts in Lowering Body Weight in Obesity: A Literature Review

2021 ◽  
Vol 14 (4) ◽  
pp. 1791-1797
Author(s):  
Eko Fuji Ariyanto ◽  
Nurul Ovifa Multom ◽  
Afiat Berbudi ◽  
Enny Rohmawaty ◽  
Budi Sujatmiko

The habits of today's society, which are influenced by economic growth and globalization have brought new lifestyles, especially those related to diet, resulting in minimal physical activity accompanied by a high calorie intake. This energy imbalance can lead to the metabolic syndrome, including obesity, which is still a burden on the world today. Some plants in Indonesia are believed to help lose weight, such as Aloe vera, Cinnamomum zeylanicum, Curcuma longa, Garcinia cambogia, and Garcinia mangostana. This literature review was conducted to determine the effects of Aloe vera, Cinnamomum zeylanicum, Curcuma longa, Garcinia cambogia, and Garcinia mangostana on weight loss and preventing obesity. The review of twelve relevant articles concluded that Aloe vera, Cinnamomum zeylanicum, Curcuma longa, Garcinia cambogia, and Garcinia mangostana have the potential to prevent and treat obesity but further research is required.

2020 ◽  
Vol 11 (2) ◽  
pp. 1716-1728
Author(s):  
Siti Nurul Najiha Othman ◽  
Pei Teng Lum ◽  
Aina Akmal Mohd Noor ◽  
Nurul Azima Mazlan ◽  
Puteri Zarith Sofea Yusri ◽  
...  

Malaysia is rich in natural and herbal resources which have the potential to be used as traditional medicine as well as cosmetics. These plant sources are used by the folklore to help in enriching their beauty. Leaves, fruits, flowers and roots of medicinal plants in Malaysia are used in cosmetic formulations to get different biological effects. Health issues with particular reference to skin issues, such as acne, dry skin, dull skin and alopecia can be alleviated by using these plants. Since time immemorial, herbal products have been used in maintaining and enhancing physical appearance of humans. Herbal cosmetics have growing demand in the world market and is an invaluable gift of nature. This review is about ten commonly available medicinal plants in Malaysia used in the cosmetic formulations which includes Aloe vera, Curcuma longa, Cocos nucifera, Cucumis sativus, Melaleuca alternifolia, Punica granatum, Garcinia mangostana, Carica papaya, Lawsonia inermis and Hibiscus rosasinensis. These are the ten plants that are commonly used traditionally in treating many skin conditions and hair problems. Different parts of the plant may produce different beneficial effects to the consumers. Using the herbal and natural ingredients in cosmetics alleviates the side effects almost to nil. This is predominantly lower than the side effects caused by synthetic cosmetics.


2020 ◽  
Author(s):  
Smith G. Nkhata ◽  
Theresa Nakoma-Ngoma ◽  
Praise M Chilenga

Abstract SARS-CoV 2 continues to disproportionately kill people across the world. To understand the reasons for such heterogeneity, we isolated dietary and environmental factors that can either prime or suppress human immunity. We grouped phytochemical and micronutrient rich food (fruits, vegetable and spices) as immunity primers while smoking, alcohol consumption, pollution, high calorie intake and diabetes as immunity suppressing factors and determined correlations with Covid-19 death per million populations (C19DM) using multiple linear regressions or where necessary, best fit trend lines. We also determined correlations between life expectancy alone or in combination with other factors and C19DM. Based on the data, we found no evidence that immunity primers explain C19DM heterogeneity across countries. This observation did not change even after including immunity suppressing factors in the models. Of all the factors under study, life expectancy (years), calorie intake (Kcal/person/day) and prevalence of diabetes (%) had significant association with C19DM (R2 = 0.301, p < 0.000). Therefore, these three factors should be further explored when trying to understand Covid-19 disproportionate mortality across countries.


2020 ◽  
Author(s):  
Smith G. Nkhata ◽  
Theresa Nakoma-Ngoma ◽  
Praise M Chilenga

Abstract SARS-CoV 2 continues to disproportionately kill people across the world. To understand the reasons for such heterogeneity, we isolated dietary and environmental factors that can either prime or suppress human immunity. We grouped phytochemical and micronutrient rich food (fruits, vegetable and spices) as immunity primers while smoking, alcohol consumption, pollution, high calorie intake and diabetes as immunity suppressing factors and determined correlations with Covid-19 death per million populations (C19DM) using multiple linear regressions or where necessary, best fit trend lines. We also determined correlations between life expectancy alone or in combination with other factors and C19DM. Based on the data, we found no evidence that immunity primers explain C19DM heterogeneity across countries. This observation did not change even after including immunity suppressing factors in the models. Of all the factors under study, life expectancy (years), calorie intake (Kcal/person/day) and prevalence of diabetes (%) had significant association with C19DM (R2 = 0.301, p < 0.000). Therefore, these three factors should be further explored when trying to understand Covid-19 disproportionate mortality across countries.


2013 ◽  
Vol 1 (1) ◽  
pp. 100
Author(s):  
Selçuk Yurtsever

It has been known that both in the world and in Turkey a continuous change has been experienced in the provision of health services in recent years. In this sense by adopting the customer(client) focused approach of either public or private sector hospitals; it has been seen that they are in the struggle for presenting a right, fast, trustuble, comfy service. The purpose of this research is to measure the satisfaction degree, expectations and perceptions of the patients in Karabük State Hospital through comparison. In this context, the patient satisfaction scale which has been developed as a result of literature review has been used and by this scale it has been tried to measure the satisfaction levels of the patients in terms of material and human factors which are the two main factors of the service that was presented. In the study, with the scales of Servqual and 0-100 Points together, in the part of the analysis MANOVA have been used. The expectations and the perceptions of the patient has been compared first by generally and then by separating to different groups according to the various criterias and in thisway it has been tried to be measured their satisfaction levels. According to the results that were obtained, although, the satisfaction levels of the patients who have taken service from Karabük State Hospital are high in terms of thedoctors and the nurses; it has been reached to the result that their satisfaction levels are low in terms of the materials that have been used at the presenting of the service and the management.


2020 ◽  
Vol 01 ◽  
Author(s):  
Ruqia Bibi ◽  
Saima Gul ◽  
Abdul Wahab ◽  
Mohammad Iqbal Khan ◽  
Murad Ali Khan

Background: The incidence of dementia is increasing as the aging population of the world is increasing. Alzheimer’s disease (AD) is the neurodegenerative disorder of the central nervous system. There are presently 7.3 million patents of AD and the number may rise to 34 million at this pace in the coming thirty years. In the disease, the level of Acetylcholine is reduced and as a result, causes the loss of cholinergic neurons in the brain. The disease is less common in Asian countries as compared to the western nations of the world. This work aimed to establish the role of the common medicinal and food plants against Alzheimer. Methods: The enzyme acetylcholinesterase (AChE) is the enzyme responsible for hydrolysis and reduction of Acetylcholine. The anti-acetylcholinesterase activity of different extracts of three local plants used as spices in the daily food, Curcuma longa, Cinnnamomum tamala, and Zingiber officinale, were determined using the Microplate Assay method. Results: The phytochemical study of the selected plants revealed the presence of alkaloids, terpenes, flavones, saponins, and tannins in these plants. The chloroform extract of all the three plants presented promising AChE inhibiting activity having IC50 >200μg/ml. A probable reason will be the alkaloids and terpenes present in the chloroform extract. Conclusion: The chloroform extract of all three plants presented promising AChE inhibiting activity and can become a reasonable therapy for the cure/ prevention of Alzheimer disease. The frequent use of these spices may be a possible reason for the fever incidence of Alzheimer in Asian countries. Further in vivo studies are required to find its action and studies to find the exact compound responsible for the action.


Author(s):  
Fabrizio Coticchia

Since the end of the bipolar era, Italy has regularly undertaken military interventions around the world, with an average of 8,000 units employed abroad in the twenty-first century. Moreover, Italy is one of the principal contributors to the UN operations. The end of the cold war represented a turning point for Italian defence, allowing for greater military dynamism. Several reforms have been approved, while public opinion changed its view regarding the armed forces. This chapter aims to provide a comprehensive perspective of the process of transformation that occurred in post-cold-war Italian defence, looking at the evolution of national strategies, military doctrines, and the structure of forces. After a brief literature review, the study highlights the process of transformation of Italian defeshnce policy since 1989. Through primary and secondary sources, the chapter illustrates the main changes that occurred, the never-ending cold-war legacies, and key challenges.


Author(s):  
Dayani Pavalakumar ◽  
Madhura Jayasinghe ◽  
Maharsha Edirisinghe ◽  
Isuru Wijesekara ◽  
Subhashinie Senadheera

Metabolites ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 267
Author(s):  
Anna Bartosiewicz ◽  
Edyta Łuszczki ◽  
Małgorzata Nagórska ◽  
Łukasz Oleksy ◽  
Artur Stolarczyk ◽  
...  

The metabolic syndrome, also known as syndrome X or the insulin resistance, is defined by the World Health Organization as a pathologic condition characterized by abdominal obesity, insulin resistance, hypertension, and hyperlipidemia. Both all over the world and in Poland, there is a shortage of nurses; most of those employed are in the pre-retirement age. However, the requirements in this profession and the patient’s right to care at the highest level remain unchanged and do not take into account the poor condition or age of working nurses, so special attention should be paid to the state of health in this professional group. There is an emphasis on the importance of the adopted attitude toward health and the resulting behaviors, such as regular weight control, following dietary recommendations, regular physical activity and participation in preventive examinations. The aim of the study was to assess the frequency of the occurrence of the metabolic syndrome, its individual components and determining the factors influencing its development in Polish nurses. The research conducted among the nurses in question included DXA (Dual Energy X-ray Absorptiometry) measurements, assessment of glucose concentration, lipid profile, blood pressure and a questionnaire survey. Almost half of the surveyed nurses have metabolic syndrome, which significantly increases the risk of developing cardiovascular diseases or diabetes. After multivariate analysis, it was found that being overweight and obesity were significant factors influenced the MS (metabolic syndrome) occurrence among Polish nurses. Being overweight increases the chances of MS occurrence 8.58 times in relation to BMI (Body Mass Index) <25, obesity increases the chances of MS occurrence 8.085 times in relation to BMI <25, and obesity class II/III increases the chances of MS occurrence 16.505 times in relation to BMI <25. Preventive and supportive measures for this professional group are needed.


2021 ◽  
Vol 14 (3) ◽  
pp. 217
Author(s):  
Jiri Patocka ◽  
Kamil Kuca ◽  
Patrik Oleksak ◽  
Eugenie Nepovimova ◽  
Martin Valis ◽  
...  

Since December 2019, SARS-CoV-2 (COVID-19) has been a worldwide pandemic with enormous consequences for human health and the world economy. Remdesivir is the only drug in the world that has been approved for the treating of COVID-19. This drug, as well as vaccination, still has uncertain effectiveness. Drug repurposing could be a promising strategy how to find an appropriate molecule: rapamycin could be one of them. The authors performed a systematic literature review of available studies on the research describing rapamycin in association with COVID-19 infection. Only peer-reviewed English-written articles from the world’s acknowledged databases Web of Science, PubMed, Springer and Scopus were involved. Five articles were eventually included in the final analysis. The findings indicate that rapamycin seems to be a suitable candidate for drug repurposing. In addition, it may represent a better candidate for COVID-19 therapy than commonly tested antivirals. It is also likely that its efficiency will not be reduced by the high rate of viral RNA mutation.


2020 ◽  
Vol 5 (2) ◽  
pp. 434-443
Author(s):  
Syarul Azman Shaharuddin ◽  
Mariam Abd Majid ◽  
Muhammad Yusof Marlon Abdullah ◽  
Abur Hamdi Usman ◽  
Siti Nor Atiqah Amran

The world of entrepreneurs in Malaysia has been led by Muslims. This has contributed to the growth of the Muslim economy. There are issues of failure in business management based on Islamic spiritual values. Spirituality is the process of the internal development of the soul. In Islam, it is based on faith in life, believing and trust in Allah Almighty, while application of the tauhid paradigm in both in this world and hereafter are related affairs. The purpose of the study is to analyze the potential of spiritual elements in the success of Muslim entrepreneurs. In this article, the researchers applied the Systematic Literature Review methodology, which focuses on research objectives. This article uses three (3) steps to analyze selected articles, i.e., by identification, screening, and eligibility. The outcome of this study had established five (5) journal articles that discussed spiritual elements that played an important role in the success of Muslim entrepreneurs, based on religious practices and values that were applied in entrepreneurship. The analysis found that the belief in Allah and the practice of religious values helped to enhance confidence and build the strong personality and traits of successful entrepreneurs. This is contributed by the elements of gratitude (Shukr), approval (riḍā), and reliance (tawakkal) after the best effort. Therefore, this study is expected to contribute to the research on entrepreneurship in Malaysia, especially for the Muslim community.


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