scholarly journals Antimicrobial Effects of the Stinging Nettle (Urtica Dioica L.).

2017 ◽  
Vol 11 (2) ◽  
pp. 10-15
Author(s):  
Kornélia Kőszegi ◽  
Erika Bekassy-Molnar ◽  
Joseph Michael Kocsis ◽  
Gyula Vatai
Keyword(s):  
Medicinal Plants ◽  
Scientific Literature ◽  
Folk Medicine ◽  
Antimicrobial Activities ◽  
Urtica Dioica ◽  
Tea Consumption ◽  
Stinging Nettle ◽  
Synthetic Drugs ◽  
Scientific Experiments ◽  
Positive Effect

Nowadays increasing attention is being paid to herbs, one of the reasons is to avoid the undesirable side effects of synthetic drugs. This is the reason why the analysis of the antimicrobial activities of medicinal plants are increasingly in the focus of scientific experiments as well. One of the best-known medicinal plants is nettle. Among the nettle species in Hungary, Stinging nettle (Urtica dioica L.) can be found in the country and is most commonly utilised for medical purposes, with a focus on its leaves and roots. Nettle tea consumption is widespread in folk medicine for treating diabetes, allergies, abdominal pain, benign prostatic hyperplasia, rheumatoid arthritis and treatment of infections. This study gives a widespread summary of the reseach results about the antimicrobal impact of Stinging Nettle (Urtica dioica L.) in the scientific literature. The papers documented a positive effect of nettle for more than 30 Gram positive and Gram negative bacterias, yeasts and fungis.

scholarly journals Cytotoxic, Antimicrobial, Antioxidant Properties and Effects on Cell Migration of Phenolic Compounds of Selected Transylvanian Medicinal Plants

Antioxidants ◽  
2020 ◽  
Vol 9 (2) ◽  
pp. 166 ◽  
Author(s):  
Rita Csepregi ◽  
Viktória Temesfői ◽  
Sourav Das ◽  
Ágnes Alberti ◽  
Csenge Anna Tóth ◽  
...  
Keyword(s):  
Cell Migration ◽  
Medicinal Plants ◽  
Biological Effects ◽  
Folk Medicine ◽  
Antioxidant Properties ◽  
Animal Experiments ◽  
Human Keratinocytes ◽  
Time Lapse ◽  
Antimicrobial Activities ◽  
Cellular Migration

Medicinal plants are widely used in folk medicine but quite often their composition and biological effects are hardly known. Our study aimed to analyze the composition, cytotoxicity, antimicrobial, antioxidant activity and cellular migration effects of Anthyllis vulneraria, Fuchsia magellanica, Fuchsia triphylla and Lysimachia nummularia used in the Romanian ethnomedicine for wounds. Liquid chromatography with mass spectrometry (LC-MS/MS) was used to analyze 50% (v/v) ethanolic and aqueous extracts of the plants’ leaves. Antimicrobial activities were estimated with a standard microdilution method. The antioxidant properties were evaluated by validated chemical cell-free and biological cell-based assays. Cytotoxic effects were performed on mouse fibroblasts and human keratinocytes with a plate reader-based method assessing intracellular adenosine triphosphate (ATP), nucleic acid and protein contents and also by a flow cytometer-based assay detecting apoptotic–necrotic cell populations. Cell migration to cover cell-free areas was visualized by time-lapse phase-contrast microscopy using standard culture inserts. Fuchsia species showed the strongest cytotoxicity and the highest antioxidant and antimicrobial activity. However, their ethanolic extracts facilitated cell migration, most probably due to their various phenolic acid, flavonoid and anthocyanin derivatives. Our data might serve as a basis for further animal experiments to explore the complex action of Fuchsia species in wound healing assays.

scholarly journals Urtica dioica (Stinging Nettle): A Pharmacologically Important Medicinal Plant Species of Himalayan Region

2020 ◽  
pp. 49-58
Author(s):  
Geeta Rawat ◽  
Alka Bameta ◽  
A. K. Gaur
Keyword(s):  
Medicinal Plants ◽  
Fungal Infections ◽  
Hepatoprotective Activity ◽  
Urtica Dioica ◽  
Medical System ◽  
Himalayan Region ◽  
Diuretic Activity ◽  
Stinging Nettle ◽  
The Family ◽  
Important Medicinal Plant

Urtica dioica (Stinging nettle) belonging to the family Urticaceae is a medicinal plantfound in the Himalayas region from Kashmir to Kumaon region (Uttarakhand.). In Himalayan region, this plant is used for the daily purpose as food as well as to serve animals. It contains various phytochemicals like phenolic acid, coumarins, flavanols, bioflavonoids, Flavan-3-ols etc which is used to cure many diseases like arthritis, constipation, Pulmonary, Liver, Intestine, Kidney, Diabetes, Fungal infections, anti-inflammatory, internal injury and wounds. It also has hepatoprotective activity, anti‑hyperlipidemic activity, diuretic activity, antimicrobial activity, anticancer activity. Researchers have reported about 30 species with 47 genera and 1,300 species worldwide used to treat different diseases. Medicinal plants have proved to be the “backbone” of traditional medical system which signifies that developing countries depend upon medicinal plants for therapeutic use.

scholarly journals Ranking Tool Created for Medicinal Plants at Risk of Being Overharvested in the Wild

2014 ◽  
Vol 5 ◽  
pp. 77-88 ◽  
Author(s):  
Lisa Marie Castle ◽  
Susan Leopold ◽  
Rachel Craft ◽  
Kelly Kindscher
Keyword(s):  
At Risk ◽  
Life History ◽  
Medicinal Plants ◽  
Urtica Dioica ◽  
Panax Quinquefolius ◽  
Conservation Priorities ◽  
Stinging Nettle ◽  
Echinacea Angustifolia ◽  
In The Wild ◽  
Explicit Criteria

We developed an adaptable, transparent tool that can be used to quantify and compare vulnerability to overharvest for wild collected medicinal plants. Subsequently, we are creating a list of the most threatened medicinal plants in temperate North America. The new tool scores species according to their life history, the effects of harvest, their abundance and range, habitat, and demand. The resulting rankings, based on explicit criteria rather than expert opinion, will make it easier to discuss areas of vulnerability and set conservation priorities. Here we present scores for 40 species assessed using the At-Risk Tool and discuss the traits that led to different scores for six example species: echinacea (Echinacea angustifolia DC. Asteraceae), peyote (Lophophora williamsii (Lem. ex Salm-Dyck) J.M. Coult. Cactaceae), sandalwood (Santalum spp. L. Santalaceae), stinging nettle (Urtica dioica L. Urticaceae), American ginseng (Panax quinquefolius L. Araliaceae) and mayapple (Podophyllum peltatum L. Berberidaceae).

Persistency of the effect ofLactuca sativaandUrtica dioicaonin vitroacidosis

2005 ◽  
Vol 2005 ◽  
pp. 225-225
Author(s):  
K. E. Kliem ◽  
R. Morgan ◽  
F. L. Mould
Keyword(s):  
Lactuca Sativa ◽  
Fermentation Medium ◽  
Urtica Dioica ◽  
Simulation Technique ◽  
Stinging Nettle ◽  
Medium Ph ◽  
Rumen Microflora ◽  
Positive Effect ◽  
The Eu

As part of the EU Framework 5 project “Rumen-Up”, plants were screened for their effect on thein vitrofermentation medium pH. Common lettuce(Lactuca sativa)and stinging nettle(Urtica dioica)were identified as having a positive effect, maintaining a higher pH when fermented with wheat over 48 hours. It was considered that the rumen microflora may adapt to the inclusion of either plant in the diet, leading to negation of the effect, and therefore reducing the opportunities for use as a supplement to prevent acidosis. This study was designed to investigate the persistency of the anti-acidosis effect using the Rumen Simulation Technique (RUSITEC), together with batchin vitrofermentation using inoculum harvested from RUSITEC.

scholarly journals Characterization of antioxidant and antimicrobial activities of nettle leaves (Urtica dioica L.)

2012 ◽  
pp. 257-272 ◽  
Author(s):  
Zoran Kukric ◽  
Ljiljana Topalic-Trivunovic ◽  
Biljana Kukavica ◽  
Snjezana Matos ◽  
Svetlana Pavicic ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Antimicrobial Activity ◽  
Antioxidant Activity ◽  
Developmental Stages ◽  
Ethanol Extract ◽  
Antimicrobial Activities ◽  
Urtica Dioica ◽  
Total Phenolic ◽  
Stinging Nettle ◽  
Enzymatic Antioxidant

Samples of stinging nettle or common nettle (Urtica dioica L.) were collected from the area of Banja Luka. To measure and evaluate the content of chlorophyll (a and b), carotenoids, and soluble proteins, as well as peroxidase activity (POD, EC 1.11.1.7.), fresh nettle leaves of different developmental stages were used. Dried nettle leaves were used to obtain ethanol extract. The dry residue of ethanol extract was dissolved in methanol and the obtained solution was used to determine the content of total phenols, flavonoids, flavonols, as well as non-enzymatic antioxidant activity and antimicrobial activity. The non-enzymatic antioxidant activity was determined by different methods: FRAP, DPPH, and ABTS. The results were compared to those of standard substances like vitamin C, BHT, and BHA. Antimicrobial activity was screened by using macrodilution method. The obtained results showed insignificantly higher content of chlorophyll, carotenoids, and proteins in young nettle leaves as well as an increase in the soluble peroxidase activities. Native electrophoresis of the soluble fraction showed the presence of two peroxidase isophorms in the soluble protein fraction of nettle leaves. The total phenolic content in nettle extracts amounted to 208.37 mg GAE/gdw, the content of total flavonoids was 20.29 mg QE/gdw, and the content of total flavonols was 22.83 mg QE/gdw. The antioxidant activity determined by FRAP method was 7.50 mM Fe(II)/gdw, whereas the antioxidant activity measured by using DPPH and ABTS methods, with IC50 values, were 31.38 and 23.55 ?g mL-1, respectively. These results showed the weak and moderate antioxidant capacity of stinging nettle. Extract of Urtica dioica L. was tested for antibacterial acivity against various Grampositive and Gram-negative bacteria: Bacillus subtilis IP 5832, Lactobacillus plantarum 299v (Lp299v), Pseudomonas aeruginosa, and Escherichia coli isolated from food and Escherichia coli isolated from urine samples. Ampicillin, erythromycin, ciprofloxacin, and gentamicin were used as positive control. The results showed that minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of the extract ranged from 9.05 to more than 149.93 mg mL-1.

Potential Uses of Vinegar as a Medicine and Related in vivo Mechanisms

2016 ◽  
Vol 86 (3-4) ◽  
pp. 127-151 ◽  
Author(s):  
Zeshan Ali ◽  
Zhenbin Wang ◽  
Rai Muhammad Amir ◽  
Shoaib Younas ◽  
Asif Wali ◽  
...  
Keyword(s):  
Chemical Structure ◽  
Review Paper ◽  
Heart Diseases ◽  
Folk Medicine ◽  
Active Role ◽  
Current Review ◽  
Different Types ◽  
Positive Effect

While the use of vinegar to fi ght against infections and other crucial conditions dates back to Hippocrates, recent research has found that vinegar consumption has a positive effect on biomarkers for diabetes, cancer, and heart diseases. Different types of vinegar have been used in the world during different time periods. Vinegar is produced by a fermentation process. Foods with a high content of carbohydrates are a good source of vinegar. Review of the results of different studies performed on vinegar components reveals that the daily use of these components has a healthy impact on the physiological and chemical structure of the human body. During the era of Hippocrates, people used vinegar as a medicine to treat wounds, which means that vinegar is one of the ancient foods used as folk medicine. The purpose of the current review paper is to provide a detailed summary of the outcome of previous studies emphasizing the role of vinegar in treatment of different diseases both in acute and chronic conditions, its in vivo mechanism and the active role of different bacteria.

Rheumatoid Arthritis: History, Stages, Epidemiology, Pathogenesis, Diagnosis and Treatment

2017 ◽  
Vol 9 (02) ◽  
Author(s):  
Abeer Fauzi Al-Rubaye ◽  
Mohanad Jawad Kadhim ◽  
Imad Hadi Hameed
Keyword(s):  
Rheumatoid Arthritis ◽  
Medicinal Plants ◽  
Systemic Disease ◽  
Modern Medicine ◽  
Whole Body ◽  
Internal Organs ◽  
Synthetic Drugs ◽  
Relieve Pain ◽  
Medicinal Treatment ◽  
Natural Drugs

The pharmacological mechanisms of the medicinal plants traditionally used for RA in Persian medicine are discussed in the current review. Further investigations are mandatory to focus on bioefficacy of these phytochemicals for finding novel natural drugs. Rheumatoid arthritis is chronic, progressive, disabling autoimmune disease characterized by systemic inflammation of joints, damaging cartilage and bone around the joints. It is a systemic disease which means that it can affect the whole body and internal organs such as lungs, heart and eyes. Although numbers of synthetic drugs are being used as standard treatment for rheumatoid arthritis but they have adverse effect that can compromise the therapeutic treatment. Unfortunately, there is still no effective known medicinal treatment that cures rheumatoid arthritis as the modern medicine can only treat the symptoms of this disease that means to relieve pain and inflammation of joints. It is possible to use the herbs and plants in various forms in order to relieve the pain and inflammation in the joints. There are so many medicinal plants that have shown anti rheumatoid arthritis properties. So the plants and plant product with significant advantages are used for the treatment of rheumatoid arthritis. The present review is focused on the medicinal plants having anti rheumatoid arthritis activity

Natural products from the traditional Moroccan pharmacopoeia: A potential lead for the prevention and treatment of COVID-19

2020 ◽  
Vol 11 (SPL1) ◽  
pp. 1278-1285
Author(s):  
Mohamed Yafout ◽  
Amine Ousaid ◽  
Ibrahim Sbai El Otmani ◽  
Youssef Khayati ◽  
Amal Ait Haj Said
Keyword(s):  
Medicinal Plants ◽  
Plant Extracts ◽  
Molecular Mechanisms ◽  
Scientific Literature ◽  
Treatment Protocol ◽  
World Health ◽  
The World ◽  
Health Organization ◽  
Promising Source

The new SARS-CoV-2 belonging to the coronaviruses family has caused a pandemic affecting millions of people around the world. This pandemic has been declared by the World Health Organization as an international public health emergency. Although several clinical trials involving a large number of drugs are currently underway, no treatment protocol for COVID-19 has been officially approved so far. Here we demonstrate through a search in the scientific literature that the traditional Moroccan pharmacopoeia, which includes more than 500 medicinal plants, is a fascinating and promising source for the research of natural molecules active against SARS-CoV-2. Multiple in-silico and in-vitro studies showed that some of the medicinal plants used by Moroccans for centuries possess inhibitory activity against SARS-CoV or SARS-CoV-2. These inhibitory activities are achieved through the different molecular mechanisms of virus penetration and replication, or indirectly through stimulation of immunity. Thus, the potential of plants, plant extracts and molecules derived from plants that are traditionally used in Morocco and have activity against SARS-CoV-2, could be explored in the search for a preventive or curative treatment against COVID-19. Furthermore, safe plants or plant extracts that are proven to stimulate immunity could be officially recommended by governments as nutritional supplements.

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